id stringlengths 1 50 | document_id stringlengths 5 50 | passages listlengths 1 1 | entities listlengths 0 849 | events listlengths 0 0 | coreferences listlengths 0 18 | relations listlengths 0 818 |
|---|---|---|---|---|---|---|
1.0alpha7.train.172 | 25227450 | [
{
"id": "1.0alpha7.train.172.sent",
"type": "sentence",
"text": [
"In fact, channelologists have had this idea for some time, but a rather general experimental finding has been that standard calmodulin inhibitors that block the calcium-dependent binding of calmodulin to its target proteins do not ... | [
{
"id": "1.0alpha7.train.172.ent0_0",
"type": "chemical",
"text": [
"calcium"
],
"offsets": [
[
161,
168
]
],
"normalized": [
{
"db_name": "pubchem:compound",
"db_id": "5460341"
}
]
},
{
"id": "1.0alpha7.train.172.... | [] | [
{
"id": "1.0alpha7.train.172.coref0",
"entity_ids": [
"1.0alpha7.train.172.ent0_0",
"1.0alpha7.train.172.ent1_1"
]
},
{
"id": "1.0alpha7.train.172.coref1",
"entity_ids": [
"1.0alpha7.train.172.ent2_0",
"1.0alpha7.train.172.ent3_1"
]
}
] | [] |
1.0alpha7.train.173 | 2068117 | [
{
"id": "1.0alpha7.train.173.sent",
"type": "sentence",
"text": [
"The amount of S223F coat protein bound to GroEL increased when the GroEL concentration was raised regardless of temperature, suggesting that even at low temperatures the improper folding of S223F coat protein exceeded the capacity ... | [
{
"id": "1.0alpha7.train.173.ent0_0",
"type": "protein",
"text": [
"GroEL"
],
"offsets": [
[
42,
47
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "3329"
},
{
"db_name": "hgnc",
"db_id": "HSPD1"
... | [] | [
{
"id": "1.0alpha7.train.173.coref0",
"entity_ids": [
"1.0alpha7.train.173.ent0_0",
"1.0alpha7.train.173.ent1_1",
"1.0alpha7.train.173.ent2_2"
]
},
{
"id": "1.0alpha7.train.173.coref1",
"entity_ids": [
"1.0alpha7.train.173.ent3_0",
"1.0alpha7.train.173.ent4_1"
... | [
{
"id": "1.0alpha7.train.173.rel0s1.0alpha7.train.173.ent0_0.o1.0alpha7.train.173.ent3_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.173.ent0_0",
"arg2_id": "1.0alpha7.train.173.ent3_0",
"normalized": []
},
{
"id": "1.0alpha7.train.173.rel0s1.0alpha7.train.173.ent0_0.o1.0alpha7.train.1... |
1.0alpha7.train.174 | 9541858 | [
{
"id": "1.0alpha7.train.174.sent",
"type": "sentence",
"text": [
"The demonstration that Axin binds GSK-3 and beta-catenin and promotes GSK-3 phosphorylation of beta-catenin suggested that Axin might be the target of the dnXgsk-3."
],
"offsets": [
[
0,
164
]
... | [
{
"id": "1.0alpha7.train.174.ent0_0",
"type": "protein",
"text": [
"beta-catenin"
],
"offsets": [
[
44,
56
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "1499"
},
{
"db_name": "hgnc",
"db_id": "... | [] | [
{
"id": "1.0alpha7.train.174.coref0",
"entity_ids": [
"1.0alpha7.train.174.ent0_0",
"1.0alpha7.train.174.ent1_1"
]
},
{
"id": "1.0alpha7.train.174.coref1",
"entity_ids": [
"1.0alpha7.train.174.ent2_0",
"1.0alpha7.train.174.ent3_1"
]
},
{
"id": "1.0alpha7.t... | [
{
"id": "1.0alpha7.train.174.rel0s1.0alpha7.train.174.ent2_0.o1.0alpha7.train.174.ent5_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.174.ent2_0",
"arg2_id": "1.0alpha7.train.174.ent5_0",
"normalized": []
},
{
"id": "1.0alpha7.train.174.rel0s1.0alpha7.train.174.ent2_0.o1.0alpha7.train.1... |
1.0alpha7.train.175 | 7486370 | [
{
"id": "1.0alpha7.train.175.sent",
"type": "sentence",
"text": [
"In complex with the drug FK506, FKBP12 binds calcineurin, inhibiting calcineurin's phosphatase activity and thus its ability to activate the transcription factor NF-AT in the T-cell receptor signal transduction pathway ( 170)."
... | [
{
"id": "1.0alpha7.train.175.ent0_0",
"type": "protein-family",
"text": [
"T-cell receptor"
],
"offsets": [
[
175,
190
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.175.ent1_0",
"type": "protein",
"text": [
"calcineurin"
],
... | [] | [
{
"id": "1.0alpha7.train.175.coref0",
"entity_ids": [
"1.0alpha7.train.175.ent0_0"
]
},
{
"id": "1.0alpha7.train.175.coref1",
"entity_ids": [
"1.0alpha7.train.175.ent1_0",
"1.0alpha7.train.175.ent2_1"
]
},
{
"id": "1.0alpha7.train.175.coref2",
"entity_ids": ... | [
{
"id": "1.0alpha7.train.175.rel0s1.0alpha7.train.175.ent3_0.o1.0alpha7.train.175.ent5_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.175.ent3_0",
"arg2_id": "1.0alpha7.train.175.ent5_0",
"normalized": []
},
{
"id": "1.0alpha7.train.175.rel1s1.0alpha7.train.175.ent1_0.o1.0alpha7.train.1... |
1.0alpha7.train.176 | 1696385 | [
{
"id": "1.0alpha7.train.176.sent",
"type": "sentence",
"text": [
"CREB phosphorylation enhances CREB binding to CREB-binding protein, thus activating gene transcription via the CRE ( 29)."
],
"offsets": [
[
0,
121
]
]
}
] | [
{
"id": "1.0alpha7.train.176.ent0_0",
"type": "protein",
"text": [
"CREB"
],
"offsets": [
[
0,
4
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "1385"
},
{
"db_name": "hgnc",
"db_id": "CREB1"
... | [] | [
{
"id": "1.0alpha7.train.176.coref0",
"entity_ids": [
"1.0alpha7.train.176.ent0_0",
"1.0alpha7.train.176.ent1_1",
"1.0alpha7.train.176.ent2_2"
]
},
{
"id": "1.0alpha7.train.176.coref1",
"entity_ids": [
"1.0alpha7.train.176.ent3_0"
]
},
{
"id": "1.0alpha7.t... | [
{
"id": "1.0alpha7.train.176.rel0s1.0alpha7.train.176.ent0_0.o1.0alpha7.train.176.ent3_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.176.ent0_0",
"arg2_id": "1.0alpha7.train.176.ent3_0",
"normalized": []
},
{
"id": "1.0alpha7.train.176.rel0s1.0alpha7.train.176.ent1_1.o1.0alpha7.train.1... |
1.0alpha7.train.177 | 9608928 | [
{
"id": "1.0alpha7.train.177.sent",
"type": "sentence",
"text": [
"Still other mechanisms are likely to be highly receptor-specific: the binding of NHERF to the β2-adrenergic receptor and the binding of Homer to metabotropic glutamate receptors, for example, depend on the presence of precise motif... | [
{
"id": "1.0alpha7.train.177.ent0_0",
"type": "protein-family",
"text": [
"Homer"
],
"offsets": [
[
136,
141
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.177.ent1_0",
"type": "protein-domain",
"text": [
"PDZ"
],
"offset... | [] | [
{
"id": "1.0alpha7.train.177.coref0",
"entity_ids": [
"1.0alpha7.train.177.ent0_0"
]
},
{
"id": "1.0alpha7.train.177.coref1",
"entity_ids": [
"1.0alpha7.train.177.ent1_0"
]
},
{
"id": "1.0alpha7.train.177.coref2",
"entity_ids": [
"1.0alpha7.train.177.ent2_0"... | [
{
"id": "1.0alpha7.train.177.rel0s1.0alpha7.train.177.ent3_0.o1.0alpha7.train.177.ent4_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.177.ent3_0",
"arg2_id": "1.0alpha7.train.177.ent4_0",
"normalized": []
},
{
"id": "1.0alpha7.train.177.rel1s1.0alpha7.train.177.ent0_0.o1.0alpha7.train.1... |
1.0alpha7.train.178 | 6906183 | [
{
"id": "1.0alpha7.train.178.sent",
"type": "sentence",
"text": [
"( A) U1 snRNP binds to the dsx pre-mRNA independently of the ESE, whereas the ESE and U1 snRNP are required for the assembly of U2, U4/U6, and U5 snRNPs on the dsx pre-mRNA."
],
"offsets": [
[
0,
173
... | [
{
"id": "1.0alpha7.train.178.ent0_0",
"type": "RNA",
"text": [
"dsx pre-mRNA"
],
"offsets": [
[
27,
39
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.178.ent1_1",
"type": "RNA",
"text": [
"dsx pre-mRNA"
],
"offsets": [
... | [] | [
{
"id": "1.0alpha7.train.178.coref0",
"entity_ids": [
"1.0alpha7.train.178.ent0_0",
"1.0alpha7.train.178.ent1_1"
]
},
{
"id": "1.0alpha7.train.178.coref1",
"entity_ids": [
"1.0alpha7.train.178.ent2_0"
]
},
{
"id": "1.0alpha7.train.178.coref2",
"entity_ids": ... | [
{
"id": "1.0alpha7.train.178.rel0s1.0alpha7.train.178.ent0_0.o1.0alpha7.train.178.ent3_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.178.ent0_0",
"arg2_id": "1.0alpha7.train.178.ent3_0",
"normalized": []
},
{
"id": "1.0alpha7.train.178.rel0s1.0alpha7.train.178.ent0_0.o1.0alpha7.train.1... |
1.0alpha7.train.179 | 16348415 | [
{
"id": "1.0alpha7.train.179.sent",
"type": "sentence",
"text": [
"First, p21 binds PCNA ( 15) through a region found by Chuang et al. to be similar to, and to compete with, the site in DNA-MCMT that mediates PCNA binding."
],
"offsets": [
[
0,
155
]
]
}
] | [
{
"id": "1.0alpha7.train.179.ent0_0",
"type": "protein",
"text": [
"PCNA"
],
"offsets": [
[
17,
21
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "5111"
},
{
"db_name": "hgnc",
"db_id": "PCNA"
... | [] | [
{
"id": "1.0alpha7.train.179.coref0",
"entity_ids": [
"1.0alpha7.train.179.ent0_0",
"1.0alpha7.train.179.ent1_1"
]
},
{
"id": "1.0alpha7.train.179.coref1",
"entity_ids": [
"1.0alpha7.train.179.ent2_0"
]
},
{
"id": "1.0alpha7.train.179.coref2",
"entity_ids": ... | [
{
"id": "1.0alpha7.train.179.rel0s1.0alpha7.train.179.ent0_0.o1.0alpha7.train.179.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.179.ent0_0",
"arg2_id": "1.0alpha7.train.179.ent2_0",
"normalized": []
},
{
"id": "1.0alpha7.train.179.rel0s1.0alpha7.train.179.ent1_1.o1.0alpha7.train.1... |
1.0alpha7.train.180 | 11991611 | [
{
"id": "1.0alpha7.train.180.sent",
"type": "sentence",
"text": [
"As shown in Figure 7A (panels labeled ‘GAL4’), GAL4 WT, DB·CR and DB·AD bound more readily than the DNA-binding domain alone to an artificial promoter, which bears four GAL4 sites fused to an unrelated HIS4 basal promoter."
],... | [
{
"id": "1.0alpha7.train.180.ent0_0",
"type": "protein-region",
"text": [
"DB·AD"
],
"offsets": [
[
67,
72
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.180.ent1_0",
"type": "DNA",
"text": [
"DNA"
],
"offsets": [
[... | [] | [
{
"id": "1.0alpha7.train.180.coref0",
"entity_ids": [
"1.0alpha7.train.180.ent0_0"
]
},
{
"id": "1.0alpha7.train.180.coref1",
"entity_ids": [
"1.0alpha7.train.180.ent1_0"
]
},
{
"id": "1.0alpha7.train.180.coref2",
"entity_ids": [
"1.0alpha7.train.180.ent2_0"... | [
{
"id": "1.0alpha7.train.180.rel0s1.0alpha7.train.180.ent1_0.o1.0alpha7.train.180.ent4_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.180.ent1_0",
"arg2_id": "1.0alpha7.train.180.ent4_0",
"normalized": []
},
{
"id": "1.0alpha7.train.180.rel1s1.0alpha7.train.180.ent0_0.o1.0alpha7.train.1... |
1.0alpha7.train.181 | 9426278 | [
{
"id": "1.0alpha7.train.181.sent",
"type": "sentence",
"text": [
"The cytoplasmic domain of the cadherin can bind directly to p120ctn as well as beta-catenin, and either protein could play a role in growth suppression."
],
"offsets": [
[
0,
152
]
]
}
] | [
{
"id": "1.0alpha7.train.181.ent0_0",
"type": "protein-family",
"text": [
"cadherin"
],
"offsets": [
[
30,
38
]
],
"normalized": [
{
"db_name": "interpro",
"db_id": "IPR039808"
}
]
},
{
"id": "1.0alpha7.train.181.e... | [] | [
{
"id": "1.0alpha7.train.181.coref0",
"entity_ids": [
"1.0alpha7.train.181.ent0_0"
]
},
{
"id": "1.0alpha7.train.181.coref1",
"entity_ids": [
"1.0alpha7.train.181.ent1_0"
]
},
{
"id": "1.0alpha7.train.181.coref2",
"entity_ids": [
"1.0alpha7.train.181.ent2_0"... | [
{
"id": "1.0alpha7.train.181.rel0s1.0alpha7.train.181.ent0_0.o1.0alpha7.train.181.ent3_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.181.ent0_0",
"arg2_id": "1.0alpha7.train.181.ent3_0",
"normalized": []
},
{
"id": "1.0alpha7.train.181.rel1s1.0alpha7.train.181.ent0_0.o1.0alpha7.train.1... |
1.0alpha7.train.182 | 19533945 | [
{
"id": "1.0alpha7.train.182.sent",
"type": "sentence",
"text": [
"As a consequence, Armadillo is no longer bound by Axin, resulting in nuclear signaling by Armadillo."
],
"offsets": [
[
0,
100
]
]
}
] | [
{
"id": "1.0alpha7.train.182.ent0_0",
"type": "protein",
"text": [
"Axin"
],
"offsets": [
[
50,
54
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "8312"
},
{
"db_name": "hgnc",
"db_id": "AXIN1"
... | [] | [
{
"id": "1.0alpha7.train.182.coref0",
"entity_ids": [
"1.0alpha7.train.182.ent0_0"
]
},
{
"id": "1.0alpha7.train.182.coref1",
"entity_ids": [
"1.0alpha7.train.182.ent1_0",
"1.0alpha7.train.182.ent2_1"
]
}
] | [
{
"id": "1.0alpha7.train.182.rel0s1.0alpha7.train.182.ent0_0.o1.0alpha7.train.182.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.182.ent0_0",
"arg2_id": "1.0alpha7.train.182.ent1_0",
"normalized": []
},
{
"id": "1.0alpha7.train.182.rel0s1.0alpha7.train.182.ent0_0.o1.0alpha7.train.1... |
1.0alpha7.train.183 | 53656 | [
{
"id": "1.0alpha7.train.183.sent",
"type": "sentence",
"text": [
"Assay for CD22Rg Binding to HEC After washing with Medium 199, HEC were incubated with 2.5 mug/ ml CD22 mRg in Medium 199, 1% BSA at 4 degrees C for 2 h, in the absence or presence of alpha2-6-sLac or alpha2-3-sLac, plasma, IgM, ha... | [
{
"id": "1.0alpha7.train.183.ent0_0",
"type": "reagent",
"text": [
"alpha2-6-sLac"
],
"offsets": [
[
184,
197
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.183.ent1_0",
"type": "reagent",
"text": [
"CD22 mRg"
],
"offsets... | [] | [
{
"id": "1.0alpha7.train.183.coref0",
"entity_ids": [
"1.0alpha7.train.183.ent0_0"
]
},
{
"id": "1.0alpha7.train.183.coref1",
"entity_ids": [
"1.0alpha7.train.183.ent1_0"
]
},
{
"id": "1.0alpha7.train.183.coref2",
"entity_ids": [
"1.0alpha7.train.183.ent2_0"... | [] |
1.0alpha7.train.184 | 3650301 | [
{
"id": "1.0alpha7.train.184.sent",
"type": "sentence",
"text": [
"Moreover, it has been found that acetyl-CoA can enhance the transcription of naked DNA (greater than 5-fold) as well as the binding of TFIID to promoter DNA in the absence of histones ( 35)."
],
"offsets": [
[
... | [
{
"id": "1.0alpha7.train.184.ent0_0",
"type": "DNA",
"text": [
"DNA"
],
"offsets": [
[
83,
86
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "25782"
},
{
"db_name": "hgnc",
"db_id": "RAB3GAP2"
... | [] | [
{
"id": "1.0alpha7.train.184.coref0",
"entity_ids": [
"1.0alpha7.train.184.ent0_0",
"1.0alpha7.train.184.ent1_1"
]
},
{
"id": "1.0alpha7.train.184.coref1",
"entity_ids": [
"1.0alpha7.train.184.ent2_0"
]
},
{
"id": "1.0alpha7.train.184.coref2",
"entity_ids": ... | [
{
"id": "1.0alpha7.train.184.rel0s1.0alpha7.train.184.ent0_0.o1.0alpha7.train.184.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.184.ent0_0",
"arg2_id": "1.0alpha7.train.184.ent2_0",
"normalized": []
},
{
"id": "1.0alpha7.train.184.rel0s1.0alpha7.train.184.ent1_1.o1.0alpha7.train.1... |
1.0alpha7.train.185 | 2941370 | [
{
"id": "1.0alpha7.train.185.sent",
"type": "sentence",
"text": [
"Rapid regulation of Cdk5 activity could occur by increased binding of free p35 to monomeric Cdk5, particularly as the generally low cytoplasmic levels of p35 (30,54) are under strict regulation, with rapid p35 turnover (half-life 2... | [
{
"id": "1.0alpha7.train.185.ent0_0",
"type": "protein-complex",
"text": [
"proteasome"
],
"offsets": [
[
267,
277
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.185.ent1_0",
"type": "protein-family",
"text": [
"ubiquitin"
],... | [] | [
{
"id": "1.0alpha7.train.185.coref0",
"entity_ids": [
"1.0alpha7.train.185.ent0_0"
]
},
{
"id": "1.0alpha7.train.185.coref1",
"entity_ids": [
"1.0alpha7.train.185.ent1_0"
]
},
{
"id": "1.0alpha7.train.185.coref2",
"entity_ids": [
"1.0alpha7.train.185.ent2_0"... | [
{
"id": "1.0alpha7.train.185.rel0s1.0alpha7.train.185.ent3_0.o1.0alpha7.train.185.ent5_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.185.ent3_0",
"arg2_id": "1.0alpha7.train.185.ent5_0",
"normalized": []
},
{
"id": "1.0alpha7.train.185.rel0s1.0alpha7.train.185.ent3_0.o1.0alpha7.train.1... |
1.0alpha7.train.186 | 25321020 | [
{
"id": "1.0alpha7.train.186.sent",
"type": "sentence",
"text": [
"It is clear, however, that only a small fraction of TLN binds PS1 under steady-state conditions (Figure 1E), indicating that the interaction is functional and not structural."
],
"offsets": [
[
0,
174
... | [
{
"id": "1.0alpha7.train.186.ent0_0",
"type": "protein",
"text": [
"PS1"
],
"offsets": [
[
62,
65
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "5663"
},
{
"db_name": "hgnc",
"db_id": "PSEN1"
... | [] | [
{
"id": "1.0alpha7.train.186.coref0",
"entity_ids": [
"1.0alpha7.train.186.ent0_0"
]
},
{
"id": "1.0alpha7.train.186.coref1",
"entity_ids": [
"1.0alpha7.train.186.ent1_0"
]
}
] | [
{
"id": "1.0alpha7.train.186.rel0s1.0alpha7.train.186.ent0_0.o1.0alpha7.train.186.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.186.ent0_0",
"arg2_id": "1.0alpha7.train.186.ent1_0",
"normalized": []
}
] |
1.0alpha7.train.187 | 15528171 | [
{
"id": "1.0alpha7.train.187.sent",
"type": "sentence",
"text": [
"(C) Comparison of the binding of 10 JNK isoforms to JIP3."
],
"offsets": [
[
0,
57
]
]
}
] | [
{
"id": "1.0alpha7.train.187.ent0_0",
"type": "protein",
"text": [
"JNK"
],
"offsets": [
[
36,
39
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "5599"
},
{
"db_name": "hgnc",
"db_id": "MAPK8"
... | [] | [
{
"id": "1.0alpha7.train.187.coref0",
"entity_ids": [
"1.0alpha7.train.187.ent0_0"
]
},
{
"id": "1.0alpha7.train.187.coref1",
"entity_ids": [
"1.0alpha7.train.187.ent1_0"
]
}
] | [
{
"id": "1.0alpha7.train.187.rel0s1.0alpha7.train.187.ent0_0.o1.0alpha7.train.187.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.187.ent0_0",
"arg2_id": "1.0alpha7.train.187.ent1_0",
"normalized": []
}
] |
1.0alpha7.train.188 | 9155411 | [
{
"id": "1.0alpha7.train.188.sent",
"type": "sentence",
"text": [
"Despite a lack of significant sequence homology, the cadherin cytoplasmic domain, APC, and LEF/ Tcf bind competitively to beta-catenin (Hü ;lsken et al., 1994 ;."
],
"offsets": [
[
0,
165
]
... | [
{
"id": "1.0alpha7.train.188.ent0_0",
"type": "protein-family",
"text": [
"cadherin"
],
"offsets": [
[
53,
61
]
],
"normalized": [
{
"db_name": "interpro",
"db_id": "IPR039808"
}
]
},
{
"id": "1.0alpha7.train.188.e... | [] | [
{
"id": "1.0alpha7.train.188.coref0",
"entity_ids": [
"1.0alpha7.train.188.ent0_0"
]
},
{
"id": "1.0alpha7.train.188.coref1",
"entity_ids": [
"1.0alpha7.train.188.ent1_0"
]
},
{
"id": "1.0alpha7.train.188.coref2",
"entity_ids": [
"1.0alpha7.train.188.ent2_0"... | [
{
"id": "1.0alpha7.train.188.rel0s1.0alpha7.train.188.ent0_0.o1.0alpha7.train.188.ent3_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.188.ent0_0",
"arg2_id": "1.0alpha7.train.188.ent3_0",
"normalized": []
},
{
"id": "1.0alpha7.train.188.rel1s1.0alpha7.train.188.ent1_0.o1.0alpha7.train.1... |
1.0alpha7.train.189 | 19483256 | [
{
"id": "1.0alpha7.train.189.sent",
"type": "sentence",
"text": [
"The binding of Hh to Ptc alleviates the repressive action of Ptc on Smo and, when Smo is derepressed, Ci proteolysis is inhibited and Ci is converted into a transcriptional activator."
],
"offsets": [
[
0,
... | [
{
"id": "1.0alpha7.train.189.ent0_0",
"type": "protein",
"text": [
"Smo"
],
"offsets": [
[
68,
71
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "6608"
},
{
"db_name": "hgnc",
"db_id": "SMO"
... | [] | [
{
"id": "1.0alpha7.train.189.coref0",
"entity_ids": [
"1.0alpha7.train.189.ent0_0",
"1.0alpha7.train.189.ent1_1"
]
},
{
"id": "1.0alpha7.train.189.coref1",
"entity_ids": [
"1.0alpha7.train.189.ent2_0"
]
},
{
"id": "1.0alpha7.train.189.coref2",
"entity_ids": ... | [
{
"id": "1.0alpha7.train.189.rel0s1.0alpha7.train.189.ent2_0.o1.0alpha7.train.189.ent3_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.189.ent2_0",
"arg2_id": "1.0alpha7.train.189.ent3_0",
"normalized": []
},
{
"id": "1.0alpha7.train.189.rel0s1.0alpha7.train.189.ent2_0.o1.0alpha7.train.1... |
1.0alpha7.train.190 | 6233612 | [
{
"id": "1.0alpha7.train.190.sent",
"type": "sentence",
"text": [
"Although the cooperativity of Arg binding to F-actin precluded an accurate determination of the dissociation constant of Arg for F-actin ( 19), the apparent Kd was 0.3 muM."
],
"offsets": [
[
0,
172
... | [
{
"id": "1.0alpha7.train.190.ent0_0",
"type": "protein",
"text": [
"F-actin"
],
"offsets": [
[
45,
52
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.190.ent1_1",
"type": "protein",
"text": [
"F-actin"
],
"offsets": [
... | [] | [
{
"id": "1.0alpha7.train.190.coref0",
"entity_ids": [
"1.0alpha7.train.190.ent0_0",
"1.0alpha7.train.190.ent1_1"
]
},
{
"id": "1.0alpha7.train.190.coref1",
"entity_ids": [
"1.0alpha7.train.190.ent2_0",
"1.0alpha7.train.190.ent3_1"
]
},
{
"id": "1.0alpha7.t... | [
{
"id": "1.0alpha7.train.190.rel0s1.0alpha7.train.190.ent0_0.o1.0alpha7.train.190.ent4_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.190.ent0_0",
"arg2_id": "1.0alpha7.train.190.ent4_0",
"normalized": []
},
{
"id": "1.0alpha7.train.190.rel0s1.0alpha7.train.190.ent0_0.o1.0alpha7.train.1... |
1.0alpha7.train.191 | 2927656 | [
{
"id": "1.0alpha7.train.191.sent",
"type": "sentence",
"text": [
"Therefore, an initial recruitment of Sp1 may also facilitate the binding of Ets-1."
],
"offsets": [
[
0,
82
]
]
}
] | [
{
"id": "1.0alpha7.train.191.ent0_0",
"type": "protein",
"text": [
"Sp1"
],
"offsets": [
[
37,
40
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "6667"
},
{
"db_name": "hgnc",
"db_id": "SP1"
... | [] | [
{
"id": "1.0alpha7.train.191.coref0",
"entity_ids": [
"1.0alpha7.train.191.ent0_0"
]
},
{
"id": "1.0alpha7.train.191.coref1",
"entity_ids": [
"1.0alpha7.train.191.ent1_0"
]
}
] | [] |
1.0alpha7.train.192 | 15894566 | [
{
"id": "1.0alpha7.train.192.sent",
"type": "sentence",
"text": [
"We examined whether the PTB domain of DAB could also bind to activated SEV."
],
"offsets": [
[
0,
75
]
]
}
] | [
{
"id": "1.0alpha7.train.192.ent0_0",
"type": "protein",
"text": [
"SEV"
],
"offsets": [
[
71,
74
]
],
"normalized": [
{
"db_name": "uniprot",
"db_id": "P13368"
}
]
},
{
"id": "1.0alpha7.train.192.ent1_0",
"typ... | [] | [
{
"id": "1.0alpha7.train.192.coref0",
"entity_ids": [
"1.0alpha7.train.192.ent0_0"
]
},
{
"id": "1.0alpha7.train.192.coref1",
"entity_ids": [
"1.0alpha7.train.192.ent1_0"
]
},
{
"id": "1.0alpha7.train.192.coref2",
"entity_ids": [
"1.0alpha7.train.192.ent2_0"... | [
{
"id": "1.0alpha7.train.192.rel0s1.0alpha7.train.192.ent0_0.o1.0alpha7.train.192.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.192.ent0_0",
"arg2_id": "1.0alpha7.train.192.ent2_0",
"normalized": []
}
] |
1.0alpha7.train.193 | 15990177 | [
{
"id": "1.0alpha7.train.193.sent",
"type": "sentence",
"text": [
"Such a scenario has been documented for the JNK MAP kinases bound to c-Jun, which can phosphorylate heterodimer partners that lack a JNK-binding site ( 29)."
],
"offsets": [
[
0,
156
]
]
}
... | [
{
"id": "1.0alpha7.train.193.ent0_0",
"type": "protein-family",
"text": [
"JNK MAP kinases"
],
"offsets": [
[
44,
59
]
],
"normalized": [
{
"db_name": "interpro",
"db_id": "IPR008351"
}
]
},
{
"id": "1.0alpha7.trai... | [] | [
{
"id": "1.0alpha7.train.193.coref0",
"entity_ids": [
"1.0alpha7.train.193.ent0_0"
]
},
{
"id": "1.0alpha7.train.193.coref1",
"entity_ids": [
"1.0alpha7.train.193.ent1_0"
]
}
] | [
{
"id": "1.0alpha7.train.193.rel0s1.0alpha7.train.193.ent0_0.o1.0alpha7.train.193.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.193.ent0_0",
"arg2_id": "1.0alpha7.train.193.ent1_0",
"normalized": []
}
] |
1.0alpha7.train.194 | 20679901 | [
{
"id": "1.0alpha7.train.194.sent",
"type": "sentence",
"text": [
"The data presented in this study clearly show that I-DOX binds specifically to TTR amyloid fibrils in tissues from patients with FAP."
],
"offsets": [
[
0,
133
]
]
}
] | [
{
"id": "1.0alpha7.train.194.ent0_0",
"type": "protein",
"text": [
"TTR"
],
"offsets": [
[
79,
82
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "7276"
},
{
"db_name": "hgnc",
"db_id": "TTR"
... | [] | [
{
"id": "1.0alpha7.train.194.coref0",
"entity_ids": [
"1.0alpha7.train.194.ent0_0"
]
},
{
"id": "1.0alpha7.train.194.coref1",
"entity_ids": [
"1.0alpha7.train.194.ent1_0"
]
},
{
"id": "1.0alpha7.train.194.coref2",
"entity_ids": [
"1.0alpha7.train.194.ent2_0"... | [
{
"id": "1.0alpha7.train.194.rel0s1.0alpha7.train.194.ent0_0.o1.0alpha7.train.194.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.194.ent0_0",
"arg2_id": "1.0alpha7.train.194.ent1_0",
"normalized": []
}
] |
1.0alpha7.train.195 | 15727450 | [
{
"id": "1.0alpha7.train.195.sent",
"type": "sentence",
"text": [
"When sal-Gal4 was used to drive ectopic expression of E(spl)Mβ in the wing imaginal disc, Gbe-B1-lacZ was clearly repressed at the sites where Gal4, and thus Mβ, was being expressed at highest levels (Fig. 6A and B), demonstrating... | [
{
"id": "1.0alpha7.train.195.ent0_0",
"type": "experiment-tag",
"text": [
"Gal4"
],
"offsets": [
[
9,
13
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.195.ent1_1",
"type": "experiment-tag",
"text": [
"Gal4"
],
"offsets":... | [] | [
{
"id": "1.0alpha7.train.195.coref0",
"entity_ids": [
"1.0alpha7.train.195.ent0_0",
"1.0alpha7.train.195.ent1_1"
]
},
{
"id": "1.0alpha7.train.195.coref1",
"entity_ids": [
"1.0alpha7.train.195.ent2_0",
"1.0alpha7.train.195.ent3_0",
"1.0alpha7.train.195.ent4_1"
... | [
{
"id": "1.0alpha7.train.195.rel0s1.0alpha7.train.195.ent6_0.o1.0alpha7.train.195.ent7_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.195.ent6_0",
"arg2_id": "1.0alpha7.train.195.ent7_0",
"normalized": []
}
] |
1.0alpha7.train.196 | 9032293 | [
{
"id": "1.0alpha7.train.196.sent",
"type": "sentence",
"text": [
"Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain."
],
"offsets": [
[
0,
92
]
]
}
] | [
{
"id": "1.0alpha7.train.196.ent0_0",
"type": "DNA",
"text": [
"DNA"
],
"offsets": [
[
36,
39
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "25782"
},
{
"db_name": "hgnc",
"db_id": "RAB3GAP2"
... | [] | [
{
"id": "1.0alpha7.train.196.coref0",
"entity_ids": [
"1.0alpha7.train.196.ent0_0"
]
},
{
"id": "1.0alpha7.train.196.coref1",
"entity_ids": [
"1.0alpha7.train.196.ent1_0",
"1.0alpha7.train.196.ent2_1"
]
}
] | [
{
"id": "1.0alpha7.train.196.rel0s1.0alpha7.train.196.ent0_0.o1.0alpha7.train.196.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.196.ent0_0",
"arg2_id": "1.0alpha7.train.196.ent1_0",
"normalized": []
},
{
"id": "1.0alpha7.train.196.rel0s1.0alpha7.train.196.ent0_0.o1.0alpha7.train.1... |
1.0alpha7.train.197 | 9083350 | [
{
"id": "1.0alpha7.train.197.sent",
"type": "sentence",
"text": [
"Therefore, binding of the TGFβ family type I receptors and the huge IP3 receptor to the FK506 binding site of FKBP12 suggests that calcineurin, if also directly bound to FKBP12 in the receptor/FKBP12/calcineurin complex, must be bi... | [
{
"id": "1.0alpha7.train.197.ent0_0",
"type": "protein",
"text": [
"calcineurin"
],
"offsets": [
[
131,
142
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "5530"
},
{
"db_name": "hgnc",
"db_id": ... | [] | [
{
"id": "1.0alpha7.train.197.coref0",
"entity_ids": [
"1.0alpha7.train.197.ent0_0",
"1.0alpha7.train.197.ent1_1"
]
},
{
"id": "1.0alpha7.train.197.coref1",
"entity_ids": [
"1.0alpha7.train.197.ent2_0"
]
},
{
"id": "1.0alpha7.train.197.coref2",
"entity_ids": ... | [
{
"id": "1.0alpha7.train.197.rel0s1.0alpha7.train.197.ent4_0.o1.0alpha7.train.197.ent7_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.197.ent4_0",
"arg2_id": "1.0alpha7.train.197.ent7_0",
"normalized": []
},
{
"id": "1.0alpha7.train.197.rel0s1.0alpha7.train.197.ent4_0.o1.0alpha7.train.1... |
1.0alpha7.train.198 | 11052504 | [
{
"id": "1.0alpha7.train.198.sent",
"type": "sentence",
"text": [
"In favor of a role for cytochrome c is the fact that Dark contains, like Apaf-1 but in contrast to Ced-4, a carboxy-terminal WD-40 repeat region, which is required though not sufficient for the binding of cytochrome c to Apaf-1 (se... | [
{
"id": "1.0alpha7.train.198.ent0_0",
"type": "protein",
"text": [
"Dark"
],
"offsets": [
[
53,
57
]
],
"normalized": [
{
"db_name": "uniprot",
"db_id": "Q7KLI1"
}
]
},
{
"id": "1.0alpha7.train.198.ent1_0",
"ty... | [] | [
{
"id": "1.0alpha7.train.198.coref0",
"entity_ids": [
"1.0alpha7.train.198.ent0_0"
]
},
{
"id": "1.0alpha7.train.198.coref1",
"entity_ids": [
"1.0alpha7.train.198.ent1_0",
"1.0alpha7.train.198.ent2_1"
]
},
{
"id": "1.0alpha7.train.198.coref2",
"entity_ids": ... | [
{
"id": "1.0alpha7.train.198.rel0s1.0alpha7.train.198.ent1_0.o1.0alpha7.train.198.ent4_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.198.ent1_0",
"arg2_id": "1.0alpha7.train.198.ent4_0",
"normalized": []
},
{
"id": "1.0alpha7.train.198.rel0s1.0alpha7.train.198.ent1_0.o1.0alpha7.train.1... |
1.0alpha7.train.199 | 19808375 | [
{
"id": "1.0alpha7.train.199.sent",
"type": "sentence",
"text": [
"Deletion experiments suggest that these regions, as well as the C- and N-termini, are vital for forming the proper homotrimeric, native structure essential for the binding of PCNA to its target proteins ( Fukuda et al., 1995; Fein ... | [
{
"id": "1.0alpha7.train.199.ent0_0",
"type": "protein",
"text": [
"PCNA"
],
"offsets": [
[
175,
179
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "5111"
},
{
"db_name": "hgnc",
"db_id": "PCNA"
... | [] | [
{
"id": "1.0alpha7.train.199.coref0",
"entity_ids": [
"1.0alpha7.train.199.ent0_0"
]
}
] | [] |
1.0alpha7.train.200 | 3655981 | [
{
"id": "1.0alpha7.train.200.sent",
"type": "sentence",
"text": [
"Furthermore, G6P binding to GS induces a conformational change, increasing its susceptibility to dephosphorylation ( 5, 6)."
],
"offsets": [
[
0,
123
]
]
}
] | [
{
"id": "1.0alpha7.train.200.ent0_0",
"type": "protein-family",
"text": [
"G6P"
],
"offsets": [
[
13,
16
]
],
"normalized": [
{
"db_name": "interpro",
"db_id": "IPR016275"
}
]
},
{
"id": "1.0alpha7.train.200.ent1_0... | [] | [
{
"id": "1.0alpha7.train.200.coref0",
"entity_ids": [
"1.0alpha7.train.200.ent0_0"
]
},
{
"id": "1.0alpha7.train.200.coref1",
"entity_ids": [
"1.0alpha7.train.200.ent1_0"
]
}
] | [
{
"id": "1.0alpha7.train.200.rel0s1.0alpha7.train.200.ent0_0.o1.0alpha7.train.200.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.200.ent0_0",
"arg2_id": "1.0alpha7.train.200.ent1_0",
"normalized": []
}
] |
1.0alpha7.train.201 | 9270266 | [
{
"id": "1.0alpha7.train.201.sent",
"type": "sentence",
"text": [
"(A) The peptide analogous to the wild-type N terminus of KCNK9 (and KCNK3) binds beta-COP from rat brain, while peptides with the NQ mutation do not (left)."
],
"offsets": [
[
0,
156
]
]
}
... | [
{
"id": "1.0alpha7.train.201.ent0_0",
"type": "protein",
"text": [
"beta-COP"
],
"offsets": [
[
81,
89
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "1315"
},
{
"db_name": "hgnc",
"db_id": "COPB... | [] | [
{
"id": "1.0alpha7.train.201.coref0",
"entity_ids": [
"1.0alpha7.train.201.ent0_0"
]
},
{
"id": "1.0alpha7.train.201.coref1",
"entity_ids": [
"1.0alpha7.train.201.ent1_0"
]
},
{
"id": "1.0alpha7.train.201.coref2",
"entity_ids": [
"1.0alpha7.train.201.ent2_0"... | [
{
"id": "1.0alpha7.train.201.rel0s1.0alpha7.train.201.ent0_0.o1.0alpha7.train.201.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.201.ent0_0",
"arg2_id": "1.0alpha7.train.201.ent1_0",
"normalized": []
},
{
"id": "1.0alpha7.train.201.rel1s1.0alpha7.train.201.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.202 | 9539483 | [
{
"id": "1.0alpha7.train.202.sent",
"type": "sentence",
"text": [
"On the other hand, the SH2 domain of Crk can potentially bind to both p130Cas and paxillin."
],
"offsets": [
[
0,
91
]
]
}
] | [
{
"id": "1.0alpha7.train.202.ent0_0",
"type": "protein",
"text": [
"Crk"
],
"offsets": [
[
37,
40
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "1398"
},
{
"db_name": "hgnc",
"db_id": "CRK"
... | [] | [
{
"id": "1.0alpha7.train.202.coref0",
"entity_ids": [
"1.0alpha7.train.202.ent0_0"
]
},
{
"id": "1.0alpha7.train.202.coref1",
"entity_ids": [
"1.0alpha7.train.202.ent1_0"
]
},
{
"id": "1.0alpha7.train.202.coref2",
"entity_ids": [
"1.0alpha7.train.202.ent2_0"... | [
{
"id": "1.0alpha7.train.202.rel0s1.0alpha7.train.202.ent0_0.o1.0alpha7.train.202.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.202.ent0_0",
"arg2_id": "1.0alpha7.train.202.ent1_0",
"normalized": []
},
{
"id": "1.0alpha7.train.202.rel1s1.0alpha7.train.202.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.203 | 1814820 | [
{
"id": "1.0alpha7.train.203.sent",
"type": "sentence",
"text": [
"TAFII250 binds directly to TBP and multiple other TAFIIs, thus serving as a potential scaffold for the multiprotein complex ( 28, 29)."
],
"offsets": [
[
0,
134
]
]
}
] | [
{
"id": "1.0alpha7.train.203.ent0_0",
"type": "protein",
"text": [
"TAFII250"
],
"offsets": [
[
0,
8
]
],
"normalized": [
{
"db_name": "uniprot",
"db_id": "P51123"
}
]
},
{
"id": "1.0alpha7.train.203.ent1_0",
"... | [] | [
{
"id": "1.0alpha7.train.203.coref0",
"entity_ids": [
"1.0alpha7.train.203.ent0_0"
]
},
{
"id": "1.0alpha7.train.203.coref1",
"entity_ids": [
"1.0alpha7.train.203.ent1_0"
]
},
{
"id": "1.0alpha7.train.203.coref2",
"entity_ids": [
"1.0alpha7.train.203.ent2_0"... | [
{
"id": "1.0alpha7.train.203.rel0s1.0alpha7.train.203.ent0_0.o1.0alpha7.train.203.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.203.ent0_0",
"arg2_id": "1.0alpha7.train.203.ent1_0",
"normalized": []
},
{
"id": "1.0alpha7.train.203.rel1s1.0alpha7.train.203.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.204 | 10947020 | [
{
"id": "1.0alpha7.train.204.sent",
"type": "sentence",
"text": [
"Since TSA induced Sp1 binding to Sp1 consensus sequences in Hep3B cells, we investigated whether TSA affected Sp1 phosphorylation, a possible cause for the increase of Sp1 binding to its consensus DNA sequences."
],
"offset... | [
{
"id": "1.0alpha7.train.204.ent0_0",
"type": "DNA",
"text": [
"DNA"
],
"offsets": [
[
197,
200
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "25782"
},
{
"db_name": "hgnc",
"db_id": "RAB3GAP2"
... | [] | [
{
"id": "1.0alpha7.train.204.coref0",
"entity_ids": [
"1.0alpha7.train.204.ent0_0"
]
},
{
"id": "1.0alpha7.train.204.coref1",
"entity_ids": [
"1.0alpha7.train.204.ent1_0",
"1.0alpha7.train.204.ent2_1",
"1.0alpha7.train.204.ent3_2",
"1.0alpha7.train.204.ent4_3"
... | [
{
"id": "1.0alpha7.train.204.rel0s1.0alpha7.train.204.ent1_0.o1.0alpha7.train.204.ent5_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.204.ent1_0",
"arg2_id": "1.0alpha7.train.204.ent5_0",
"normalized": []
},
{
"id": "1.0alpha7.train.204.rel0s1.0alpha7.train.204.ent2_1.o1.0alpha7.train.2... |
1.0alpha7.train.205 | 21745005 | [
{
"id": "1.0alpha7.train.205.sent",
"type": "sentence",
"text": [
"Systemic administration of 3-NPA (30 mg kg-1 per day for 3 days) induced a 170% increase in [3]- PK 11195 binding, and expression of HSP27."
],
"offsets": [
[
0,
139
]
]
}
] | [
{
"id": "1.0alpha7.train.205.ent0_0",
"type": "protein",
"text": [
"HSP27"
],
"offsets": [
[
133,
138
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "3315"
},
{
"db_name": "hgnc",
"db_id": "HSPB1... | [] | [
{
"id": "1.0alpha7.train.205.coref0",
"entity_ids": [
"1.0alpha7.train.205.ent0_0"
]
},
{
"id": "1.0alpha7.train.205.coref1",
"entity_ids": [
"1.0alpha7.train.205.ent1_0"
]
},
{
"id": "1.0alpha7.train.205.coref2",
"entity_ids": [
"1.0alpha7.train.205.ent2_0"... | [] |
1.0alpha7.train.206 | 22146010 | [
{
"id": "1.0alpha7.train.206.sent",
"type": "sentence",
"text": [
"This interpretation is consistent with stopped flow experiments on the formation of the catalytic complex, which were interpreted as evidence that the second dIII binds to the dI dimer with a Kd of 20-50 M [ 24]."
],
"offse... | [
{
"id": "1.0alpha7.train.206.ent0_0",
"type": "protein",
"text": [
"dI"
],
"offsets": [
[
176,
178
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.206.ent1_0",
"type": "protein",
"text": [
"dIII"
],
"offsets": [
[
... | [] | [
{
"id": "1.0alpha7.train.206.coref0",
"entity_ids": [
"1.0alpha7.train.206.ent0_0"
]
},
{
"id": "1.0alpha7.train.206.coref1",
"entity_ids": [
"1.0alpha7.train.206.ent1_0"
]
}
] | [
{
"id": "1.0alpha7.train.206.rel0s1.0alpha7.train.206.ent0_0.o1.0alpha7.train.206.ent0_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.206.ent0_0",
"arg2_id": "1.0alpha7.train.206.ent0_0",
"normalized": []
},
{
"id": "1.0alpha7.train.206.rel1s1.0alpha7.train.206.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.207 | 10369809 | [
{
"id": "1.0alpha7.train.207.sent",
"type": "sentence",
"text": [
"75 89 90 91 Two of them, A63V and K70T, are located in exon 2b within the consensus pattern of sequence repeats of alpha-TM and could alter tropomyosin binding to actin."
],
"offsets": [
[
0,
169
... | [
{
"id": "1.0alpha7.train.207.ent0_0",
"type": "protein-family",
"text": [
"alpha-TM"
],
"offsets": [
[
115,
123
]
],
"normalized": [
{
"db_name": "pfam",
"db_id": "PF00261"
}
]
},
{
"id": "1.0alpha7.train.207.ent1_... | [] | [
{
"id": "1.0alpha7.train.207.coref0",
"entity_ids": [
"1.0alpha7.train.207.ent0_0"
]
},
{
"id": "1.0alpha7.train.207.coref1",
"entity_ids": [
"1.0alpha7.train.207.ent1_0"
]
},
{
"id": "1.0alpha7.train.207.coref2",
"entity_ids": [
"1.0alpha7.train.207.ent2_0"... | [
{
"id": "1.0alpha7.train.207.rel0s1.0alpha7.train.207.ent1_0.o1.0alpha7.train.207.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.207.ent1_0",
"arg2_id": "1.0alpha7.train.207.ent2_0",
"normalized": []
}
] |
1.0alpha7.train.208 | 639982 | [
{
"id": "1.0alpha7.train.208.sent",
"type": "sentence",
"text": [
"The majority of gp160 remained bound to calreticulin despite addition of ATP (not shown)."
],
"offsets": [
[
0,
89
]
]
}
] | [
{
"id": "1.0alpha7.train.208.ent0_0",
"type": "protein",
"text": [
"gp160"
],
"offsets": [
[
16,
21
]
],
"normalized": [
{
"db_name": "uniprot",
"db_id": "Q0H5Z4"
}
]
},
{
"id": "1.0alpha7.train.208.ent1_0",
"t... | [] | [
{
"id": "1.0alpha7.train.208.coref0",
"entity_ids": [
"1.0alpha7.train.208.ent0_0"
]
},
{
"id": "1.0alpha7.train.208.coref1",
"entity_ids": [
"1.0alpha7.train.208.ent1_0"
]
},
{
"id": "1.0alpha7.train.208.coref2",
"entity_ids": [
"1.0alpha7.train.208.ent2_0"... | [
{
"id": "1.0alpha7.train.208.rel0s1.0alpha7.train.208.ent0_0.o1.0alpha7.train.208.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.208.ent0_0",
"arg2_id": "1.0alpha7.train.208.ent2_0",
"normalized": []
}
] |
1.0alpha7.train.209 | 23900170 | [
{
"id": "1.0alpha7.train.209.sent",
"type": "sentence",
"text": [
"Because PIP2 was added in the form of micelles, the effects of actin and PIP2 on profilin binding to gephyrin cannot be compared in terms of affinities."
],
"offsets": [
[
0,
152
]
]
}
] | [
{
"id": "1.0alpha7.train.209.ent0_0",
"type": "protein",
"text": [
"gephyrin"
],
"offsets": [
[
101,
109
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "10243"
},
{
"db_name": "hgnc",
"db_id": "G... | [] | [
{
"id": "1.0alpha7.train.209.coref0",
"entity_ids": [
"1.0alpha7.train.209.ent0_0"
]
},
{
"id": "1.0alpha7.train.209.coref1",
"entity_ids": [
"1.0alpha7.train.209.ent1_0"
]
},
{
"id": "1.0alpha7.train.209.coref2",
"entity_ids": [
"1.0alpha7.train.209.ent2_0"... | [
{
"id": "1.0alpha7.train.209.rel0s1.0alpha7.train.209.ent0_0.o1.0alpha7.train.209.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.209.ent0_0",
"arg2_id": "1.0alpha7.train.209.ent1_0",
"normalized": []
}
] |
1.0alpha7.train.210 | 9126838 | [
{
"id": "1.0alpha7.train.210.sent",
"type": "sentence",
"text": [
"This situation is similar to that of pI cells, where overexpression of the GTP-bound form of Galphai, GalphaiQ205L, also influences the orientation of the spindle."
],
"offsets": [
[
0,
163
]
... | [
{
"id": "1.0alpha7.train.210.ent0_0",
"type": "chemical",
"text": [
"GTP"
],
"offsets": [
[
75,
78
]
],
"normalized": [
{
"db_name": "pubchem:compound",
"db_id": "135398633"
}
]
},
{
"id": "1.0alpha7.train.210.ent1... | [] | [
{
"id": "1.0alpha7.train.210.coref0",
"entity_ids": [
"1.0alpha7.train.210.ent0_0"
]
},
{
"id": "1.0alpha7.train.210.coref1",
"entity_ids": [
"1.0alpha7.train.210.ent1_0"
]
},
{
"id": "1.0alpha7.train.210.coref2",
"entity_ids": [
"1.0alpha7.train.210.ent2_0"... | [
{
"id": "1.0alpha7.train.210.rel0s1.0alpha7.train.210.ent0_0.o1.0alpha7.train.210.ent3_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.210.ent0_0",
"arg2_id": "1.0alpha7.train.210.ent3_0",
"normalized": []
}
] |
1.0alpha7.train.211 | 5293344 | [
{
"id": "1.0alpha7.train.211.sent",
"type": "sentence",
"text": [
"Therefore, we hypothesized that co-stimulatory molecules that preferentially bind CD28 or CTLA-4 would have dramatically altered biological properties."
],
"offsets": [
[
0,
151
]
]
}
] | [
{
"id": "1.0alpha7.train.211.ent0_0",
"type": "protein",
"text": [
"CD28"
],
"offsets": [
[
82,
86
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "940"
},
{
"db_name": "hgnc",
"db_id": "CD28"
... | [] | [
{
"id": "1.0alpha7.train.211.coref0",
"entity_ids": [
"1.0alpha7.train.211.ent0_0"
]
},
{
"id": "1.0alpha7.train.211.coref1",
"entity_ids": [
"1.0alpha7.train.211.ent1_0"
]
}
] | [] |
1.0alpha7.train.212 | 9255615 | [
{
"id": "1.0alpha7.train.212.sent",
"type": "sentence",
"text": [
"Using electrophoretic mobility shift assays (EMSA), we found that Dfd binds to this fragment ( S3/240bpwt; Figure 5D)."
],
"offsets": [
[
0,
118
]
]
}
] | [
{
"id": "1.0alpha7.train.212.ent0_0",
"type": "experimental-construct",
"text": [
"S3/240bpwt"
],
"offsets": [
[
95,
105
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.212.ent1_0",
"type": "protein",
"text": [
"Dfd"
],
"o... | [] | [
{
"id": "1.0alpha7.train.212.coref0",
"entity_ids": [
"1.0alpha7.train.212.ent0_0"
]
},
{
"id": "1.0alpha7.train.212.coref1",
"entity_ids": [
"1.0alpha7.train.212.ent1_0"
]
},
{
"id": "1.0alpha7.train.212.coref2",
"entity_ids": [
"1.0alpha7.train.212.ent2_0"... | [] |
1.0alpha7.train.213 | 1356396 | [
{
"id": "1.0alpha7.train.213.sent",
"type": "sentence",
"text": [
"The INK family has a specificity for the early G1 kinases Cdk4 and Cdk6 complexed with D-type cyclins, while the CIP family is partial to Cdk2 bound to either cyclin A or E."
],
"offsets": [
[
0,
173
... | [
{
"id": "1.0alpha7.train.213.ent0_0",
"type": "protein-family",
"text": [
"D-type cyclins"
],
"offsets": [
[
87,
101
]
],
"normalized": [
{
"db_name": "interpro",
"db_id": "IPR015451"
}
]
},
{
"id": "1.0alpha7.trai... | [] | [
{
"id": "1.0alpha7.train.213.coref0",
"entity_ids": [
"1.0alpha7.train.213.ent0_0"
]
},
{
"id": "1.0alpha7.train.213.coref1",
"entity_ids": [
"1.0alpha7.train.213.ent1_0"
]
},
{
"id": "1.0alpha7.train.213.coref2",
"entity_ids": [
"1.0alpha7.train.213.ent2_0"... | [
{
"id": "1.0alpha7.train.213.rel0s1.0alpha7.train.213.ent0_0.o1.0alpha7.train.213.ent5_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.213.ent0_0",
"arg2_id": "1.0alpha7.train.213.ent5_0",
"normalized": []
},
{
"id": "1.0alpha7.train.213.rel1s1.0alpha7.train.213.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.214 | 19530807 | [
{
"id": "1.0alpha7.train.214.sent",
"type": "sentence",
"text": [
"These results suggest that most of the synergistic coactivation by CRP2 requires efficient binding of SRF to multiple SREs."
],
"offsets": [
[
0,
123
]
]
}
] | [
{
"id": "1.0alpha7.train.214.ent0_0",
"type": "DNA",
"text": [
"SREs"
],
"offsets": [
[
118,
122
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.214.ent1_0",
"type": "protein",
"text": [
"SRF"
],
"offsets": [
[
... | [] | [
{
"id": "1.0alpha7.train.214.coref0",
"entity_ids": [
"1.0alpha7.train.214.ent0_0"
]
},
{
"id": "1.0alpha7.train.214.coref1",
"entity_ids": [
"1.0alpha7.train.214.ent1_0"
]
},
{
"id": "1.0alpha7.train.214.coref2",
"entity_ids": [
"1.0alpha7.train.214.ent2_0"... | [
{
"id": "1.0alpha7.train.214.rel0s1.0alpha7.train.214.ent0_0.o1.0alpha7.train.214.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.214.ent0_0",
"arg2_id": "1.0alpha7.train.214.ent1_0",
"normalized": []
}
] |
1.0alpha7.train.215 | 7548236 | [
{
"id": "1.0alpha7.train.215.sent",
"type": "sentence",
"text": [
"These membrane lipids bind to the actin-binding domains of AC ( Yonezawa et al 1991a, Kusano et al 1999) and are capable of inhibiting AC binding to actin in vitro."
],
"offsets": [
[
0,
164
]
... | [
{
"id": "1.0alpha7.train.215.ent0_0",
"type": "protein-family",
"text": [
"AC"
],
"offsets": [
[
59,
61
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.215.ent1_1",
"type": "protein-family",
"text": [
"AC"
],
"offsets": [
... | [] | [
{
"id": "1.0alpha7.train.215.coref0",
"entity_ids": [
"1.0alpha7.train.215.ent0_0",
"1.0alpha7.train.215.ent1_1"
]
},
{
"id": "1.0alpha7.train.215.coref1",
"entity_ids": [
"1.0alpha7.train.215.ent2_0",
"1.0alpha7.train.215.ent3_1"
]
},
{
"id": "1.0alpha7.t... | [
{
"id": "1.0alpha7.train.215.rel0s1.0alpha7.train.215.ent0_0.o1.0alpha7.train.215.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.215.ent0_0",
"arg2_id": "1.0alpha7.train.215.ent2_0",
"normalized": []
},
{
"id": "1.0alpha7.train.215.rel0s1.0alpha7.train.215.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.216 | 2066872 | [
{
"id": "1.0alpha7.train.216.sent",
"type": "sentence",
"text": [
"In addition, Redlitz et al. (10) showed that activated pro-plasma carboxypeptidase B and plasma carboxypeptidase N diminish the binding of plasminogen to U937 cells and that fibrinolysis occurs more rapidly in pro-plasma carboxypep... | [
{
"id": "1.0alpha7.train.216.ent0_0",
"type": "cell",
"text": [
"U937"
],
"offsets": [
[
154,
158
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.216.ent1_0",
"type": "protein",
"text": [
"carboxypeptidase B"
],
"offsets":... | [] | [
{
"id": "1.0alpha7.train.216.coref0",
"entity_ids": [
"1.0alpha7.train.216.ent0_0"
]
},
{
"id": "1.0alpha7.train.216.coref1",
"entity_ids": [
"1.0alpha7.train.216.ent1_0",
"1.0alpha7.train.216.ent2_1"
]
},
{
"id": "1.0alpha7.train.216.coref2",
"entity_ids": ... | [] |
1.0alpha7.train.217 | 206727 | [
{
"id": "1.0alpha7.train.217.sent",
"type": "sentence",
"text": [
"Tyrosine Phosphorylation of p190 Correlates with Enhanced p120 GAP Binding in Vivo; Because p120 protein preferentially binds phosphorylated p190 in vitro, we compared the levels of native p120•p190 complex formation in normal 3Y1 ... | [
{
"id": "1.0alpha7.train.217.ent0_0",
"type": "cell",
"text": [
"SR3Y1"
],
"offsets": [
[
280,
285
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.217.ent1_0",
"type": "cell",
"text": [
"v-Src-transformed 3Y1 cells"
],
"of... | [] | [
{
"id": "1.0alpha7.train.217.coref0",
"entity_ids": [
"1.0alpha7.train.217.ent0_0",
"1.0alpha7.train.217.ent1_0"
]
},
{
"id": "1.0alpha7.train.217.coref1",
"entity_ids": [
"1.0alpha7.train.217.ent2_0",
"1.0alpha7.train.217.ent3_1",
"1.0alpha7.train.217.ent4_2"
... | [
{
"id": "1.0alpha7.train.217.rel0s1.0alpha7.train.217.ent2_0.o1.0alpha7.train.217.ent6_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.217.ent2_0",
"arg2_id": "1.0alpha7.train.217.ent6_0",
"normalized": []
},
{
"id": "1.0alpha7.train.217.rel0s1.0alpha7.train.217.ent3_1.o1.0alpha7.train.2... |
1.0alpha7.train.218 | 3554320 | [
{
"id": "1.0alpha7.train.218.sent",
"type": "sentence",
"text": [
"Furthermore, we determined that this regionalized editing of the collagen substrate was orchestrated by the stimulated expression of collagenase-1, which was bound to the SMC plasma membrane."
],
"offsets": [
[
... | [
{
"id": "1.0alpha7.train.218.ent0_0",
"type": "protein-family",
"text": [
"collagen"
],
"offsets": [
[
65,
73
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.218.ent1_0",
"type": "cell",
"text": [
"SMC"
],
"offsets": [
... | [] | [
{
"id": "1.0alpha7.train.218.coref0",
"entity_ids": [
"1.0alpha7.train.218.ent0_0"
]
},
{
"id": "1.0alpha7.train.218.coref1",
"entity_ids": [
"1.0alpha7.train.218.ent1_0"
]
},
{
"id": "1.0alpha7.train.218.coref2",
"entity_ids": [
"1.0alpha7.train.218.ent2_0"... | [] |
1.0alpha7.train.219 | 15995413 | [
{
"id": "1.0alpha7.train.219.sent",
"type": "sentence",
"text": [
"After transfection of vectors expressing MUC1 and GSK3beta, 293 cells were subjected to immunoprecipitation with anti-MUC1 and the precipitates were analyzed for binding of MUC1 to beta-catenin."
],
"offsets": [
[
... | [
{
"id": "1.0alpha7.train.219.ent0_0",
"type": "protein",
"text": [
"beta-catenin"
],
"offsets": [
[
181,
193
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "1499"
},
{
"db_name": "hgnc",
"db_id":... | [] | [
{
"id": "1.0alpha7.train.219.coref0",
"entity_ids": [
"1.0alpha7.train.219.ent0_0"
]
},
{
"id": "1.0alpha7.train.219.coref1",
"entity_ids": [
"1.0alpha7.train.219.ent1_0",
"1.0alpha7.train.219.ent2_1",
"1.0alpha7.train.219.ent3_2"
]
},
{
"id": "1.0alpha7.t... | [] |
1.0alpha7.train.220 | 20571476 | [
{
"id": "1.0alpha7.train.220.sent",
"type": "sentence",
"text": [
"This orientation shows the actin-binding surface of profilin [14,15] , which is predominately composed of the C-terminal helix (H3) and the bottom three strands ( 4, 5 and 6) of the central sheet."
],
"offsets": [
[
... | [
{
"id": "1.0alpha7.train.220.ent0_0",
"type": "protein-family",
"text": [
"actin"
],
"offsets": [
[
27,
32
]
],
"normalized": [
{
"db_name": "pfam",
"db_id": "PF00022"
}
]
},
{
"id": "1.0alpha7.train.220.ent1_0",
... | [] | [
{
"id": "1.0alpha7.train.220.coref0",
"entity_ids": [
"1.0alpha7.train.220.ent0_0"
]
},
{
"id": "1.0alpha7.train.220.coref1",
"entity_ids": [
"1.0alpha7.train.220.ent1_0"
]
}
] | [
{
"id": "1.0alpha7.train.220.rel0s1.0alpha7.train.220.ent0_0.o1.0alpha7.train.220.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.220.ent0_0",
"arg2_id": "1.0alpha7.train.220.ent1_0",
"normalized": []
}
] |
1.0alpha7.train.221 | 19503598 | [
{
"id": "1.0alpha7.train.221.sent",
"type": "sentence",
"text": [
"Binding of Cdc20 and Cdh1 to the APC is differentially regulated."
],
"offsets": [
[
0,
65
]
]
}
] | [
{
"id": "1.0alpha7.train.221.ent0_0",
"type": "protein",
"text": [
"Cdh1"
],
"offsets": [
[
21,
25
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "999"
},
{
"db_name": "hgnc",
"db_id": "CDH1"
... | [] | [
{
"id": "1.0alpha7.train.221.coref0",
"entity_ids": [
"1.0alpha7.train.221.ent0_0"
]
},
{
"id": "1.0alpha7.train.221.coref1",
"entity_ids": [
"1.0alpha7.train.221.ent1_0"
]
},
{
"id": "1.0alpha7.train.221.coref2",
"entity_ids": [
"1.0alpha7.train.221.ent2_0"... | [
{
"id": "1.0alpha7.train.221.rel0s1.0alpha7.train.221.ent1_0.o1.0alpha7.train.221.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.221.ent1_0",
"arg2_id": "1.0alpha7.train.221.ent2_0",
"normalized": []
},
{
"id": "1.0alpha7.train.221.rel1s1.0alpha7.train.221.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.222 | 12684514 | [
{
"id": "1.0alpha7.train.222.sent",
"type": "sentence",
"text": [
"With the goal of learning more about the mechanisms responsible for insulating activity, we have identified and characterized SBP ( scs binding protein), a protein component of the scs nucleoprotein complex."
],
"offsets": ... | [
{
"id": "1.0alpha7.train.222.ent0_0",
"type": "protein",
"text": [
"SBP"
],
"offsets": [
[
126,
129
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.222.ent1_0",
"type": "protein",
"text": [
"scs binding protein"
],
"offset... | [] | [
{
"id": "1.0alpha7.train.222.coref0",
"entity_ids": [
"1.0alpha7.train.222.ent0_0",
"1.0alpha7.train.222.ent1_0"
]
},
{
"id": "1.0alpha7.train.222.coref1",
"entity_ids": [
"1.0alpha7.train.222.ent2_0",
"1.0alpha7.train.222.ent3_1"
]
}
] | [
{
"id": "1.0alpha7.train.222.rel0s1.0alpha7.train.222.ent0_0.o1.0alpha7.train.222.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.222.ent0_0",
"arg2_id": "1.0alpha7.train.222.ent2_0",
"normalized": []
},
{
"id": "1.0alpha7.train.222.rel0s1.0alpha7.train.222.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.223 | 4871993 | [
{
"id": "1.0alpha7.train.223.sent",
"type": "sentence",
"text": [
"Thus, the binding of Porc with Wg appears to be necessary for the stimulation of the N-glycosylation of Wg."
],
"offsets": [
[
0,
107
]
]
}
] | [
{
"id": "1.0alpha7.train.223.ent0_0",
"type": "protein",
"text": [
"Wg"
],
"offsets": [
[
31,
33
]
],
"normalized": [
{
"db_name": "uniprot",
"db_id": "P09615"
}
]
},
{
"id": "1.0alpha7.train.223.ent1_1",
"type... | [] | [
{
"id": "1.0alpha7.train.223.coref0",
"entity_ids": [
"1.0alpha7.train.223.ent0_0",
"1.0alpha7.train.223.ent1_1"
]
},
{
"id": "1.0alpha7.train.223.coref1",
"entity_ids": [
"1.0alpha7.train.223.ent2_0"
]
}
] | [
{
"id": "1.0alpha7.train.223.rel0s1.0alpha7.train.223.ent0_0.o1.0alpha7.train.223.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.223.ent0_0",
"arg2_id": "1.0alpha7.train.223.ent2_0",
"normalized": []
},
{
"id": "1.0alpha7.train.223.rel0s1.0alpha7.train.223.ent1_1.o1.0alpha7.train.2... |
1.0alpha7.train.224 | 19761788 | [
{
"id": "1.0alpha7.train.224.sent",
"type": "sentence",
"text": [
"Pals1 (or Sdt) binds to the Crb-PBM motif (CrbPBM) via its single PDZ domain."
],
"offsets": [
[
0,
77
]
]
}
] | [
{
"id": "1.0alpha7.train.224.ent0_0",
"type": "protein",
"text": [
"Sdt"
],
"offsets": [
[
10,
13
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "64398"
},
{
"db_name": "hgnc",
"db_id": "MPP5"
... | [] | [
{
"id": "1.0alpha7.train.224.coref0",
"entity_ids": [
"1.0alpha7.train.224.ent0_0",
"1.0alpha7.train.224.ent1_0"
]
},
{
"id": "1.0alpha7.train.224.coref1",
"entity_ids": [
"1.0alpha7.train.224.ent2_0",
"1.0alpha7.train.224.ent3_0"
]
},
{
"id": "1.0alpha7.t... | [] |
1.0alpha7.train.225 | 13846927 | [
{
"id": "1.0alpha7.train.225.sent",
"type": "sentence",
"text": [
"Under these conditions, Hbp binds heme in a 1:1 molar ratio (unpublished data)."
],
"offsets": [
[
0,
79
]
]
}
] | [
{
"id": "1.0alpha7.train.225.ent0_0",
"type": "protein",
"text": [
"Hbp"
],
"offsets": [
[
24,
27
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "566"
},
{
"db_name": "hgnc",
"db_id": "AZU1"
... | [] | [
{
"id": "1.0alpha7.train.225.coref0",
"entity_ids": [
"1.0alpha7.train.225.ent0_0"
]
},
{
"id": "1.0alpha7.train.225.coref1",
"entity_ids": [
"1.0alpha7.train.225.ent1_0"
]
}
] | [
{
"id": "1.0alpha7.train.225.rel0s1.0alpha7.train.225.ent0_0.o1.0alpha7.train.225.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.225.ent0_0",
"arg2_id": "1.0alpha7.train.225.ent1_0",
"normalized": []
}
] |
1.0alpha7.train.226 | 3506549 | [
{
"id": "1.0alpha7.train.226.sent",
"type": "sentence",
"text": [
"Both Axin and Axil bind not only to GSK-3beta but also to beta-catenin and APC ( 14-20) and promote GSK-3beta-dependent phosphorylation of beta-catenin and APC ( 14, 15, 19, 21, 22)."
],
"offsets": [
[
0,
... | [
{
"id": "1.0alpha7.train.226.ent0_0",
"type": "protein",
"text": [
"Axil"
],
"offsets": [
[
14,
18
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "8313"
},
{
"db_name": "hgnc",
"db_id": "AXIN2"
... | [] | [
{
"id": "1.0alpha7.train.226.coref0",
"entity_ids": [
"1.0alpha7.train.226.ent0_0"
]
},
{
"id": "1.0alpha7.train.226.coref1",
"entity_ids": [
"1.0alpha7.train.226.ent1_0",
"1.0alpha7.train.226.ent2_1"
]
},
{
"id": "1.0alpha7.train.226.coref2",
"entity_ids": ... | [
{
"id": "1.0alpha7.train.226.rel0s1.0alpha7.train.226.ent3_0.o1.0alpha7.train.226.ent4_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.226.ent3_0",
"arg2_id": "1.0alpha7.train.226.ent4_0",
"normalized": []
},
{
"id": "1.0alpha7.train.226.rel0s1.0alpha7.train.226.ent3_0.o1.0alpha7.train.2... |
1.0alpha7.train.227 | 11347599 | [
{
"id": "1.0alpha7.train.227.sent",
"type": "sentence",
"text": [
"Even though transportin can bind an M9 signal and the BIB domain simultaneously, it appears unlikely that transportin normally would import the two substrates at the same time: import of the trimeric M9-transportin-BIB complex is a... | [
{
"id": "1.0alpha7.train.227.ent0_0",
"type": "protein",
"text": [
"transportin"
],
"offsets": [
[
12,
23
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "3842"
},
{
"db_name": "hgnc",
"db_id": "T... | [] | [
{
"id": "1.0alpha7.train.227.coref0",
"entity_ids": [
"1.0alpha7.train.227.ent0_0",
"1.0alpha7.train.227.ent1_1",
"1.0alpha7.train.227.ent2_2",
"1.0alpha7.train.227.ent3_3"
]
},
{
"id": "1.0alpha7.train.227.coref1",
"entity_ids": [
"1.0alpha7.train.227.ent4_0"
... | [
{
"id": "1.0alpha7.train.227.rel0s1.0alpha7.train.227.ent0_0.o1.0alpha7.train.227.ent4_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.227.ent0_0",
"arg2_id": "1.0alpha7.train.227.ent4_0",
"normalized": []
},
{
"id": "1.0alpha7.train.227.rel0s1.0alpha7.train.227.ent1_1.o1.0alpha7.train.2... |
1.0alpha7.train.228 | 19530653 | [
{
"id": "1.0alpha7.train.228.sent",
"type": "sentence",
"text": [
"In vitro, HUA1 binds three tested AG RNA fragments from the second intron, one including the 5 splice site and the other two including the putative polyadenylation sites for the large AG RNAs."
],
"offsets": [
[
... | [
{
"id": "1.0alpha7.train.228.ent0_0",
"type": "RNA",
"text": [
"AG RNA"
],
"offsets": [
[
34,
40
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.228.ent1_0",
"type": "protein",
"text": [
"HUA1"
],
"offsets": [
[
... | [] | [
{
"id": "1.0alpha7.train.228.coref0",
"entity_ids": [
"1.0alpha7.train.228.ent0_0"
]
},
{
"id": "1.0alpha7.train.228.coref1",
"entity_ids": [
"1.0alpha7.train.228.ent1_0"
]
}
] | [
{
"id": "1.0alpha7.train.228.rel0s1.0alpha7.train.228.ent0_0.o1.0alpha7.train.228.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.228.ent0_0",
"arg2_id": "1.0alpha7.train.228.ent1_0",
"normalized": []
}
] |
1.0alpha7.train.229 | 11405650 | [
{
"id": "1.0alpha7.train.229.sent",
"type": "sentence",
"text": [
"Nature, 377, 246-248 [Medline] orlich, D. , Henklein, P. , Laskey, R.A. and Hartmann, E. (1996a) A 41 amino acid motif in importin alpha confers binding to importin beta and hence transit into the nucleus."
],
"offsets": [
... | [
{
"id": "1.0alpha7.train.229.ent0_0",
"type": "protein-family",
"text": [
"importin alpha"
],
"offsets": [
[
122,
136
]
],
"normalized": [
{
"db_name": "interpro",
"db_id": "IPR040122"
}
]
},
{
"id": "1.0alpha7.tra... | [] | [
{
"id": "1.0alpha7.train.229.coref0",
"entity_ids": [
"1.0alpha7.train.229.ent0_0"
]
},
{
"id": "1.0alpha7.train.229.coref1",
"entity_ids": [
"1.0alpha7.train.229.ent1_0"
]
}
] | [
{
"id": "1.0alpha7.train.229.rel0s1.0alpha7.train.229.ent0_0.o1.0alpha7.train.229.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.229.ent0_0",
"arg2_id": "1.0alpha7.train.229.ent1_0",
"normalized": []
}
] |
1.0alpha7.train.230 | 1570746 | [
{
"id": "1.0alpha7.train.230.sent",
"type": "sentence",
"text": [
"In addition, we show that the gelsolin S1 peptide PS1 does not hinder binding of cofilin or PS2 to F-actin; this also argues against the model proposed by Hatanaka et al. ( 24)."
],
"offsets": [
[
0,
1... | [
{
"id": "1.0alpha7.train.230.ent0_0",
"type": "experimental-construct",
"text": [
"gelsolin S1"
],
"offsets": [
[
30,
41
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.230.ent1_0",
"type": "protein",
"text": [
"F-actin"
],
... | [] | [
{
"id": "1.0alpha7.train.230.coref0",
"entity_ids": [
"1.0alpha7.train.230.ent0_0"
]
},
{
"id": "1.0alpha7.train.230.coref1",
"entity_ids": [
"1.0alpha7.train.230.ent1_0"
]
},
{
"id": "1.0alpha7.train.230.coref2",
"entity_ids": [
"1.0alpha7.train.230.ent2_0"... | [
{
"id": "1.0alpha7.train.230.rel0s1.0alpha7.train.230.ent1_0.o1.0alpha7.train.230.ent5_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.230.ent1_0",
"arg2_id": "1.0alpha7.train.230.ent5_0",
"normalized": []
}
] |
1.0alpha7.train.231 | 15937016 | [
{
"id": "1.0alpha7.train.231.sent",
"type": "sentence",
"text": [
"Furthermore, it has been shown that GSK-3beta phosphorylates APC and that the phosphorylation enhances the binding of APC to beta-catenin ( 37)."
],
"offsets": [
[
0,
144
]
]
}
] | [
{
"id": "1.0alpha7.train.231.ent0_0",
"type": "protein",
"text": [
"APC"
],
"offsets": [
[
61,
64
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "324"
},
{
"db_name": "hgnc",
"db_id": "APC"
... | [] | [
{
"id": "1.0alpha7.train.231.coref0",
"entity_ids": [
"1.0alpha7.train.231.ent0_0",
"1.0alpha7.train.231.ent1_1"
]
},
{
"id": "1.0alpha7.train.231.coref1",
"entity_ids": [
"1.0alpha7.train.231.ent2_0"
]
},
{
"id": "1.0alpha7.train.231.coref2",
"entity_ids": ... | [
{
"id": "1.0alpha7.train.231.rel0s1.0alpha7.train.231.ent0_0.o1.0alpha7.train.231.ent3_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.231.ent0_0",
"arg2_id": "1.0alpha7.train.231.ent3_0",
"normalized": []
},
{
"id": "1.0alpha7.train.231.rel0s1.0alpha7.train.231.ent1_1.o1.0alpha7.train.2... |
1.0alpha7.train.232 | 9049233 | [
{
"id": "1.0alpha7.train.232.sent",
"type": "sentence",
"text": [
"Binding of FasL to Fas or cross-linking Fas with agonistic antibodies (IgM class anti-Fas antibody, or IgG3 class anti-APO1 antibody) induces apoptosis in Fas-bearing cells (Trauth et al., 1989 ; Yonehara et al., 1989 ; Itoh et al.... | [
{
"id": "1.0alpha7.train.232.ent0_0",
"type": "protein",
"text": [
"FasL"
],
"offsets": [
[
11,
15
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "356"
},
{
"db_name": "hgnc",
"db_id": "FASLG"
... | [] | [
{
"id": "1.0alpha7.train.232.coref0",
"entity_ids": [
"1.0alpha7.train.232.ent0_0"
]
},
{
"id": "1.0alpha7.train.232.coref1",
"entity_ids": [
"1.0alpha7.train.232.ent1_0",
"1.0alpha7.train.232.ent2_1",
"1.0alpha7.train.232.ent3_2",
"1.0alpha7.train.232.ent4_3"
... | [
{
"id": "1.0alpha7.train.232.rel0s1.0alpha7.train.232.ent0_0.o1.0alpha7.train.232.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.232.ent0_0",
"arg2_id": "1.0alpha7.train.232.ent1_0",
"normalized": []
},
{
"id": "1.0alpha7.train.232.rel0s1.0alpha7.train.232.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.233 | 6238942 | [
{
"id": "1.0alpha7.train.233.sent",
"type": "sentence",
"text": [
"( B) ELISA demonstrating the reduced binding of the Ab to BDNF after modification with the caging group and its successful reactivation by UV light."
],
"offsets": [
[
0,
148
]
]
}
] | [
{
"id": "1.0alpha7.train.233.ent0_0",
"type": "protein",
"text": [
"BDNF"
],
"offsets": [
[
58,
62
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "627"
},
{
"db_name": "hgnc",
"db_id": "BDNF"
... | [] | [
{
"id": "1.0alpha7.train.233.coref0",
"entity_ids": [
"1.0alpha7.train.233.ent0_0"
]
},
{
"id": "1.0alpha7.train.233.coref1",
"entity_ids": [
"1.0alpha7.train.233.ent1_0"
]
},
{
"id": "1.0alpha7.train.233.coref2",
"entity_ids": [
"1.0alpha7.train.233.ent2_0"... | [] |
1.0alpha7.train.234 | 4397443 | [
{
"id": "1.0alpha7.train.234.sent",
"type": "sentence",
"text": [
"Immunoprecipitation of p53 was followed by Western blot analysis to determine the type and level of Mdm2 bound to p53 under each of these conditions."
],
"offsets": [
[
0,
149
]
]
}
] | [
{
"id": "1.0alpha7.train.234.ent0_0",
"type": "protein",
"text": [
"Mdm2"
],
"offsets": [
[
100,
104
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "4193"
},
{
"db_name": "hgnc",
"db_id": "MDM2"
... | [] | [
{
"id": "1.0alpha7.train.234.coref0",
"entity_ids": [
"1.0alpha7.train.234.ent0_0"
]
},
{
"id": "1.0alpha7.train.234.coref1",
"entity_ids": [
"1.0alpha7.train.234.ent1_0",
"1.0alpha7.train.234.ent2_1"
]
}
] | [
{
"id": "1.0alpha7.train.234.rel0s1.0alpha7.train.234.ent0_0.o1.0alpha7.train.234.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.234.ent0_0",
"arg2_id": "1.0alpha7.train.234.ent1_0",
"normalized": []
},
{
"id": "1.0alpha7.train.234.rel0s1.0alpha7.train.234.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.235 | 2477089 | [
{
"id": "1.0alpha7.train.235.sent",
"type": "sentence",
"text": [
"Binding of E1A to CBP amino acids 1805-1891 prevents binding of the histone acetyltransferase P/CAF, whereas E1A binding to CBP amino acids 2058-2163 prevents binding of the co-activator P/CIP ( 5, 12)."
],
"offsets": [
... | [
{
"id": "1.0alpha7.train.235.ent0_0",
"type": "protein",
"text": [
"E1A"
],
"offsets": [
[
11,
14
]
],
"normalized": [
{
"db_name": "uniprot",
"db_id": "P03255"
}
]
},
{
"id": "1.0alpha7.train.235.ent1_1",
"typ... | [] | [
{
"id": "1.0alpha7.train.235.coref0",
"entity_ids": [
"1.0alpha7.train.235.ent0_0",
"1.0alpha7.train.235.ent1_1"
]
},
{
"id": "1.0alpha7.train.235.coref1",
"entity_ids": [
"1.0alpha7.train.235.ent2_0",
"1.0alpha7.train.235.ent3_1"
]
},
{
"id": "1.0alpha7.t... | [
{
"id": "1.0alpha7.train.235.rel0s1.0alpha7.train.235.ent0_0.o1.0alpha7.train.235.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.235.ent0_0",
"arg2_id": "1.0alpha7.train.235.ent2_0",
"normalized": []
},
{
"id": "1.0alpha7.train.235.rel0s1.0alpha7.train.235.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.236 | 3115715 | [
{
"id": "1.0alpha7.train.236.sent",
"type": "sentence",
"text": [
"As expected, conversion of the TAGA element into a consensus TATA box increased f:TFIID binding to the LRP-2 promoter, leading to increased protection of the TATA box region and downstream promoter sequences (Fig. 4 B, comparelanes... | [
{
"id": "1.0alpha7.train.236.ent0_0",
"type": "DNA",
"text": [
"TATA box"
],
"offsets": [
[
61,
69
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.236.ent1_1",
"type": "DNA",
"text": [
"TATA box"
],
"offsets": [
[
... | [] | [
{
"id": "1.0alpha7.train.236.coref0",
"entity_ids": [
"1.0alpha7.train.236.ent0_0",
"1.0alpha7.train.236.ent1_1"
]
},
{
"id": "1.0alpha7.train.236.coref1",
"entity_ids": [
"1.0alpha7.train.236.ent2_0"
]
},
{
"id": "1.0alpha7.train.236.coref2",
"entity_ids": ... | [
{
"id": "1.0alpha7.train.236.rel0s1.0alpha7.train.236.ent2_0.o1.0alpha7.train.236.ent4_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.236.ent2_0",
"arg2_id": "1.0alpha7.train.236.ent4_0",
"normalized": []
}
] |
1.0alpha7.train.237 | 1544583 | [
{
"id": "1.0alpha7.train.237.sent",
"type": "sentence",
"text": [
"The mutation replacing Ser-39 with Ala eliminated the phosphorylation-dependent regulation of actin binding of fascin, indicating that phosphorylation at this site regulates the actin binding ability of fascin."
],
"offsets... | [
{
"id": "1.0alpha7.train.237.ent0_0",
"type": "protein",
"text": [
"fascin"
],
"offsets": [
[
111,
117
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "6624"
},
{
"db_name": "hgnc",
"db_id": "FSCN... | [] | [
{
"id": "1.0alpha7.train.237.coref0",
"entity_ids": [
"1.0alpha7.train.237.ent0_0",
"1.0alpha7.train.237.ent1_1"
]
},
{
"id": "1.0alpha7.train.237.coref1",
"entity_ids": [
"1.0alpha7.train.237.ent2_0",
"1.0alpha7.train.237.ent3_1"
]
}
] | [
{
"id": "1.0alpha7.train.237.rel0s1.0alpha7.train.237.ent0_0.o1.0alpha7.train.237.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.237.ent0_0",
"arg2_id": "1.0alpha7.train.237.ent2_0",
"normalized": []
},
{
"id": "1.0alpha7.train.237.rel0s1.0alpha7.train.237.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.238 | 9128447 | [
{
"id": "1.0alpha7.train.238.sent",
"type": "sentence",
"text": [
"Slit significantly increased the binding of srGAP1 to Robo1 ( Figure 4C, lane 2, compared to lane 1)."
],
"offsets": [
[
0,
101
]
]
}
] | [
{
"id": "1.0alpha7.train.238.ent0_0",
"type": "protein",
"text": [
"Robo1"
],
"offsets": [
[
54,
59
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "6091"
},
{
"db_name": "hgnc",
"db_id": "ROBO1"
... | [] | [
{
"id": "1.0alpha7.train.238.coref0",
"entity_ids": [
"1.0alpha7.train.238.ent0_0"
]
},
{
"id": "1.0alpha7.train.238.coref1",
"entity_ids": [
"1.0alpha7.train.238.ent1_0"
]
},
{
"id": "1.0alpha7.train.238.coref2",
"entity_ids": [
"1.0alpha7.train.238.ent2_0"... | [
{
"id": "1.0alpha7.train.238.rel0s1.0alpha7.train.238.ent0_0.o1.0alpha7.train.238.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.238.ent0_0",
"arg2_id": "1.0alpha7.train.238.ent2_0",
"normalized": []
}
] |
1.0alpha7.train.239 | 22183532 | [
{
"id": "1.0alpha7.train.239.sent",
"type": "sentence",
"text": [
"The heparin-binding property of apoE plays an important role in the sequestration step of the heparan sulfate proteoglycan (HSPG)/ LRP metabolic pathway as well as in the independent HSPG pathway [ 5."
],
"offsets": [
... | [
{
"id": "1.0alpha7.train.239.ent0_0",
"type": "chemical",
"text": [
"heparin"
],
"offsets": [
[
4,
11
]
],
"normalized": [
{
"db_name": "pubchem:compound",
"db_id": "772"
}
]
},
{
"id": "1.0alpha7.train.239.ent1_0"... | [] | [
{
"id": "1.0alpha7.train.239.coref0",
"entity_ids": [
"1.0alpha7.train.239.ent0_0"
]
},
{
"id": "1.0alpha7.train.239.coref1",
"entity_ids": [
"1.0alpha7.train.239.ent1_0",
"1.0alpha7.train.239.ent2_1",
"1.0alpha7.train.239.ent3_0"
]
},
{
"id": "1.0alpha7.t... | [
{
"id": "1.0alpha7.train.239.rel0s1.0alpha7.train.239.ent0_0.o1.0alpha7.train.239.ent4_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.239.ent0_0",
"arg2_id": "1.0alpha7.train.239.ent4_0",
"normalized": []
}
] |
1.0alpha7.train.240 | 992182 | [
{
"id": "1.0alpha7.train.240.sent",
"type": "sentence",
"text": [
"Full-length p21, which binds to both Cdk-cyclin and PCNA, effectively inhibits DNA replication (Fig. 7 A), whereas GST control protein is not inhibitory."
],
"offsets": [
[
0,
153
]
]
}
] | [
{
"id": "1.0alpha7.train.240.ent0_0",
"type": "protein",
"text": [
"PCNA"
],
"offsets": [
[
52,
56
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "5111"
},
{
"db_name": "hgnc",
"db_id": "PCNA"
... | [] | [
{
"id": "1.0alpha7.train.240.coref0",
"entity_ids": [
"1.0alpha7.train.240.ent0_0"
]
},
{
"id": "1.0alpha7.train.240.coref1",
"entity_ids": [
"1.0alpha7.train.240.ent1_0"
]
},
{
"id": "1.0alpha7.train.240.coref2",
"entity_ids": [
"1.0alpha7.train.240.ent2_0"... | [
{
"id": "1.0alpha7.train.240.rel0s1.0alpha7.train.240.ent2_0.o1.0alpha7.train.240.ent3_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.240.ent2_0",
"arg2_id": "1.0alpha7.train.240.ent3_0",
"normalized": []
},
{
"id": "1.0alpha7.train.240.rel1s1.0alpha7.train.240.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.241 | 23035520 | [
{
"id": "1.0alpha7.train.241.sent",
"type": "sentence",
"text": [
"Thus several different mutations that disrupt calcium binding and calcium-dependent syntaxin 1A binding to the C2A domain of synaptotagmin 1 do not reverse the inhibitory effect of microinjected C2A fragments on calcium-regulated s... | [
{
"id": "1.0alpha7.train.241.ent0_0",
"type": "protein",
"text": [
"syntaxin 1A"
],
"offsets": [
[
84,
95
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "6804"
},
{
"db_name": "hgnc",
"db_id": "S... | [] | [
{
"id": "1.0alpha7.train.241.coref0",
"entity_ids": [
"1.0alpha7.train.241.ent0_0"
]
},
{
"id": "1.0alpha7.train.241.coref1",
"entity_ids": [
"1.0alpha7.train.241.ent1_0"
]
},
{
"id": "1.0alpha7.train.241.coref2",
"entity_ids": [
"1.0alpha7.train.241.ent2_0"... | [
{
"id": "1.0alpha7.train.241.rel0s1.0alpha7.train.241.ent2_0.o1.0alpha7.train.241.ent3_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.241.ent2_0",
"arg2_id": "1.0alpha7.train.241.ent3_0",
"normalized": []
},
{
"id": "1.0alpha7.train.241.rel0s1.0alpha7.train.241.ent2_0.o1.0alpha7.train.2... |
1.0alpha7.train.242 | 16028298 | [
{
"id": "1.0alpha7.train.242.sent",
"type": "sentence",
"text": [
"The relative proportion of TBP bound to GST-TADIV of the total present in the crude extract (Fig. 2) was found to be about 1/10 of that of the TAFIIs as determined by densitometric analysis (data not shown)."
],
"offsets": ... | [
{
"id": "1.0alpha7.train.242.ent0_0",
"type": "protein-family",
"text": [
"TAFIIs"
],
"offsets": [
[
143,
149
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.242.ent1_0",
"type": "protein",
"text": [
"TBP"
],
"offsets": [
... | [] | [
{
"id": "1.0alpha7.train.242.coref0",
"entity_ids": [
"1.0alpha7.train.242.ent0_0"
]
},
{
"id": "1.0alpha7.train.242.coref1",
"entity_ids": [
"1.0alpha7.train.242.ent1_0"
]
},
{
"id": "1.0alpha7.train.242.coref2",
"entity_ids": [
"1.0alpha7.train.242.ent2_0"... | [
{
"id": "1.0alpha7.train.242.rel0s1.0alpha7.train.242.ent1_0.o1.0alpha7.train.242.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.242.ent1_0",
"arg2_id": "1.0alpha7.train.242.ent2_0",
"normalized": []
}
] |
1.0alpha7.train.243 | 888051 | [
{
"id": "1.0alpha7.train.243.sent",
"type": "sentence",
"text": [
"These findings suggest a complex reciprocal relationship between regulation of adducin function by calmodulin binding and phosphorylation by PKA and PKC."
],
"offsets": [
[
0,
153
]
]
}
] | [
{
"id": "1.0alpha7.train.243.ent0_0",
"type": "protein-family",
"text": [
"PKC"
],
"offsets": [
[
149,
152
]
],
"normalized": [
{
"db_name": "interpro",
"db_id": "IPR014376"
}
]
},
{
"id": "1.0alpha7.train.243.ent1... | [] | [
{
"id": "1.0alpha7.train.243.coref0",
"entity_ids": [
"1.0alpha7.train.243.ent0_0"
]
},
{
"id": "1.0alpha7.train.243.coref1",
"entity_ids": [
"1.0alpha7.train.243.ent1_0"
]
},
{
"id": "1.0alpha7.train.243.coref2",
"entity_ids": [
"1.0alpha7.train.243.ent2_0"... | [
{
"id": "1.0alpha7.train.243.rel0s1.0alpha7.train.243.ent2_0.o1.0alpha7.train.243.ent3_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.243.ent2_0",
"arg2_id": "1.0alpha7.train.243.ent3_0",
"normalized": []
}
] |
1.0alpha7.train.244 | 18055440 | [
{
"id": "1.0alpha7.train.244.sent",
"type": "sentence",
"text": [
"At present, we do not know whether Arp11 binds directly to Arp1 or actin."
],
"offsets": [
[
0,
73
]
]
}
] | [
{
"id": "1.0alpha7.train.244.ent0_0",
"type": "protein",
"text": [
"Arp1"
],
"offsets": [
[
59,
63
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "10121"
},
{
"db_name": "hgnc",
"db_id": "ACTR1A"... | [] | [
{
"id": "1.0alpha7.train.244.coref0",
"entity_ids": [
"1.0alpha7.train.244.ent0_0"
]
},
{
"id": "1.0alpha7.train.244.coref1",
"entity_ids": [
"1.0alpha7.train.244.ent1_0"
]
},
{
"id": "1.0alpha7.train.244.coref2",
"entity_ids": [
"1.0alpha7.train.244.ent2_0"... | [] |
1.0alpha7.train.245 | 19306498 | [
{
"id": "1.0alpha7.train.245.sent",
"type": "sentence",
"text": [
"In vivo binding of hAxin to APC, -catenin and GSK3 ."
],
"offsets": [
[
0,
52
]
]
}
] | [
{
"id": "1.0alpha7.train.245.ent0_0",
"type": "protein",
"text": [
"APC"
],
"offsets": [
[
28,
31
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "324"
},
{
"db_name": "hgnc",
"db_id": "APC"
... | [] | [
{
"id": "1.0alpha7.train.245.coref0",
"entity_ids": [
"1.0alpha7.train.245.ent0_0"
]
},
{
"id": "1.0alpha7.train.245.coref1",
"entity_ids": [
"1.0alpha7.train.245.ent1_0"
]
},
{
"id": "1.0alpha7.train.245.coref2",
"entity_ids": [
"1.0alpha7.train.245.ent2_0"... | [
{
"id": "1.0alpha7.train.245.rel0s1.0alpha7.train.245.ent0_0.o1.0alpha7.train.245.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.245.ent0_0",
"arg2_id": "1.0alpha7.train.245.ent1_0",
"normalized": []
},
{
"id": "1.0alpha7.train.245.rel1s1.0alpha7.train.245.ent1_0.o1.0alpha7.train.2... |
1.0alpha7.train.246 | 11440019 | [
{
"id": "1.0alpha7.train.246.sent",
"type": "sentence",
"text": [
"The ATP-bound form of Hsp70 binds and releases peptides rapidly, whereas the ADP-bound form binds and releases them slowly (Palleros et al., 1991 ; Schmid et al., 1994 ; Szabo et al., 1994 )."
],
"offsets": [
[
... | [
{
"id": "1.0alpha7.train.246.ent0_0",
"type": "protein",
"text": [
"Hsp70"
],
"offsets": [
[
22,
27
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "3308"
},
{
"db_name": "hgnc",
"db_id": "HSPA4"
... | [] | [
{
"id": "1.0alpha7.train.246.coref0",
"entity_ids": [
"1.0alpha7.train.246.ent0_0"
]
},
{
"id": "1.0alpha7.train.246.coref1",
"entity_ids": [
"1.0alpha7.train.246.ent1_0"
]
},
{
"id": "1.0alpha7.train.246.coref2",
"entity_ids": [
"1.0alpha7.train.246.ent2_0"... | [
{
"id": "1.0alpha7.train.246.rel0s1.0alpha7.train.246.ent0_0.o1.0alpha7.train.246.ent4_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.246.ent0_0",
"arg2_id": "1.0alpha7.train.246.ent4_0",
"normalized": []
},
{
"id": "1.0alpha7.train.246.rel1s1.0alpha7.train.246.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.247 | 15546592 | [
{
"id": "1.0alpha7.train.247.sent",
"type": "sentence",
"text": [
"To confirm the specificity for interaction between EID-1 and Rb in vivo, we tested the binding of endogenous Rb to wild-type EID-1 versus the C180G mutation in transfected mammalian cells."
],
"offsets": [
[
0... | [
{
"id": "1.0alpha7.train.247.ent0_0",
"type": "protein",
"text": [
"EID-1"
],
"offsets": [
[
51,
56
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "23741"
},
{
"db_name": "hgnc",
"db_id": "EID1"
... | [] | [
{
"id": "1.0alpha7.train.247.coref0",
"entity_ids": [
"1.0alpha7.train.247.ent0_0",
"1.0alpha7.train.247.ent1_1"
]
},
{
"id": "1.0alpha7.train.247.coref1",
"entity_ids": [
"1.0alpha7.train.247.ent2_0",
"1.0alpha7.train.247.ent3_1"
]
}
] | [
{
"id": "1.0alpha7.train.247.rel0s1.0alpha7.train.247.ent0_0.o1.0alpha7.train.247.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.247.ent0_0",
"arg2_id": "1.0alpha7.train.247.ent2_0",
"normalized": []
},
{
"id": "1.0alpha7.train.247.rel0s1.0alpha7.train.247.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.248 | 18222181 | [
{
"id": "1.0alpha7.train.248.sent",
"type": "sentence",
"text": [
"None of the mutations affected the binding of APC11 to APC2 (our unpublished data)."
],
"offsets": [
[
0,
83
]
]
}
] | [
{
"id": "1.0alpha7.train.248.ent0_0",
"type": "protein",
"text": [
"APC2"
],
"offsets": [
[
55,
59
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "10297"
},
{
"db_name": "hgnc",
"db_id": "APC2"
... | [] | [
{
"id": "1.0alpha7.train.248.coref0",
"entity_ids": [
"1.0alpha7.train.248.ent0_0"
]
},
{
"id": "1.0alpha7.train.248.coref1",
"entity_ids": [
"1.0alpha7.train.248.ent1_0"
]
}
] | [
{
"id": "1.0alpha7.train.248.rel0s1.0alpha7.train.248.ent0_0.o1.0alpha7.train.248.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.248.ent0_0",
"arg2_id": "1.0alpha7.train.248.ent1_0",
"normalized": []
}
] |
1.0alpha7.train.249 | 9490745 | [
{
"id": "1.0alpha7.train.249.sent",
"type": "sentence",
"text": [
"In parallel control experiments, all TRP tails failed to bind INAD from InaDP215 head extracts."
],
"offsets": [
[
0,
95
]
]
}
] | [
{
"id": "1.0alpha7.train.249.ent0_0",
"type": "protein-family",
"text": [
"TRP"
],
"offsets": [
[
37,
40
]
],
"normalized": [
{
"db_name": "interpro",
"db_id": "IPR010308"
}
]
},
{
"id": "1.0alpha7.train.249.ent1_0... | [] | [
{
"id": "1.0alpha7.train.249.coref0",
"entity_ids": [
"1.0alpha7.train.249.ent0_0"
]
},
{
"id": "1.0alpha7.train.249.coref1",
"entity_ids": [
"1.0alpha7.train.249.ent1_0"
]
},
{
"id": "1.0alpha7.train.249.coref2",
"entity_ids": [
"1.0alpha7.train.249.ent2_0"... | [
{
"id": "1.0alpha7.train.249.rel0s1.0alpha7.train.249.ent0_0.o1.0alpha7.train.249.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.249.ent0_0",
"arg2_id": "1.0alpha7.train.249.ent1_0",
"normalized": []
}
] |
1.0alpha7.train.250 | 15406395 | [
{
"id": "1.0alpha7.train.250.sent",
"type": "sentence",
"text": [
"Interestingly, we saw strong binding of Gal4 to the GC-rich region, even in the absence of galactose, which agrees with previous work by others, showing that the transcriptional activity of Gal4 is not regulated by its DNA-binding ... | [
{
"id": "1.0alpha7.train.250.ent0_0",
"type": "protein",
"text": [
"Gal4"
],
"offsets": [
[
40,
44
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "3960"
},
{
"db_name": "hgnc",
"db_id": "LGALS4"
... | [] | [
{
"id": "1.0alpha7.train.250.coref0",
"entity_ids": [
"1.0alpha7.train.250.ent0_0",
"1.0alpha7.train.250.ent1_1"
]
},
{
"id": "1.0alpha7.train.250.coref1",
"entity_ids": [
"1.0alpha7.train.250.ent2_0"
]
},
{
"id": "1.0alpha7.train.250.coref2",
"entity_ids": ... | [
{
"id": "1.0alpha7.train.250.rel0s1.0alpha7.train.250.ent0_0.o1.0alpha7.train.250.ent6_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.250.ent0_0",
"arg2_id": "1.0alpha7.train.250.ent6_0",
"normalized": []
},
{
"id": "1.0alpha7.train.250.rel0s1.0alpha7.train.250.ent1_1.o1.0alpha7.train.2... |
1.0alpha7.train.251 | 25223190 | [
{
"id": "1.0alpha7.train.251.sent",
"type": "sentence",
"text": [
"Blockade of either VASP binding to ActA ( Smith et al. 1996 ) or Profilin binding to VASP ( Kang et al. 1997 ) impairs Listeria motility, implying a role for Profilin in accelerating the actin-dependent motility."
],
"offse... | [
{
"id": "1.0alpha7.train.251.ent0_0",
"type": "protein",
"text": [
"ActA"
],
"offsets": [
[
35,
39
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "58"
},
{
"db_name": "hgnc",
"db_id": "ACTA1"
... | [] | [
{
"id": "1.0alpha7.train.251.coref0",
"entity_ids": [
"1.0alpha7.train.251.ent0_0"
]
},
{
"id": "1.0alpha7.train.251.coref1",
"entity_ids": [
"1.0alpha7.train.251.ent1_0",
"1.0alpha7.train.251.ent2_1"
]
},
{
"id": "1.0alpha7.train.251.coref2",
"entity_ids": ... | [
{
"id": "1.0alpha7.train.251.rel0s1.0alpha7.train.251.ent0_0.o1.0alpha7.train.251.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.251.ent0_0",
"arg2_id": "1.0alpha7.train.251.ent1_0",
"normalized": []
},
{
"id": "1.0alpha7.train.251.rel0s1.0alpha7.train.251.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.252 | 5301491 | [
{
"id": "1.0alpha7.train.252.sent",
"type": "sentence",
"text": [
"The presence of similar motifs to those found in all known GTPases suggests that menin could similarly exhibit GTP binding activity as well as GTP-hydrolyzing activity."
],
"offsets": [
[
0,
168
... | [
{
"id": "1.0alpha7.train.252.ent0_0",
"type": "protein",
"text": [
"menin"
],
"offsets": [
[
81,
86
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "4221"
},
{
"db_name": "hgnc",
"db_id": "MEN1"
... | [] | [
{
"id": "1.0alpha7.train.252.coref0",
"entity_ids": [
"1.0alpha7.train.252.ent0_0"
]
},
{
"id": "1.0alpha7.train.252.coref1",
"entity_ids": [
"1.0alpha7.train.252.ent1_0",
"1.0alpha7.train.252.ent2_1"
]
},
{
"id": "1.0alpha7.train.252.coref2",
"entity_ids": ... | [
{
"id": "1.0alpha7.train.252.rel0s1.0alpha7.train.252.ent0_0.o1.0alpha7.train.252.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.252.ent0_0",
"arg2_id": "1.0alpha7.train.252.ent1_0",
"normalized": []
},
{
"id": "1.0alpha7.train.252.rel0s1.0alpha7.train.252.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.254 | 3099102 | [
{
"id": "1.0alpha7.train.254.sent",
"type": "sentence",
"text": [
"The finding that SLB can bind to Lhx3 and Lhx4 suggests a possible role in modulating transcription."
],
"offsets": [
[
0,
100
]
]
}
] | [
{
"id": "1.0alpha7.train.254.ent0_0",
"type": "protein",
"text": [
"Lhx3"
],
"offsets": [
[
33,
37
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "8022"
},
{
"db_name": "hgnc",
"db_id": "LHX3"
... | [] | [
{
"id": "1.0alpha7.train.254.coref0",
"entity_ids": [
"1.0alpha7.train.254.ent0_0"
]
},
{
"id": "1.0alpha7.train.254.coref1",
"entity_ids": [
"1.0alpha7.train.254.ent1_0"
]
},
{
"id": "1.0alpha7.train.254.coref2",
"entity_ids": [
"1.0alpha7.train.254.ent2_0"... | [
{
"id": "1.0alpha7.train.254.rel0s1.0alpha7.train.254.ent0_0.o1.0alpha7.train.254.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.254.ent0_0",
"arg2_id": "1.0alpha7.train.254.ent2_0",
"normalized": []
},
{
"id": "1.0alpha7.train.254.rel1s1.0alpha7.train.254.ent1_0.o1.0alpha7.train.2... |
1.0alpha7.train.255 | 5161992 | [
{
"id": "1.0alpha7.train.255.sent",
"type": "sentence",
"text": [
"We show that Hsp70 binding is regulated by the phosphorylation state of the turn motif, one of the two conserved carboxyl-terminal phosphorylation sites, and that Hsp70 binds mature PKC that has become dephosphorylated, rather than... | [
{
"id": "1.0alpha7.train.255.ent0_0",
"type": "protein",
"text": [
"Hsp70"
],
"offsets": [
[
13,
18
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "3308"
},
{
"db_name": "hgnc",
"db_id": "HSPA4"
... | [] | [
{
"id": "1.0alpha7.train.255.coref0",
"entity_ids": [
"1.0alpha7.train.255.ent0_0",
"1.0alpha7.train.255.ent1_1"
]
},
{
"id": "1.0alpha7.train.255.coref1",
"entity_ids": [
"1.0alpha7.train.255.ent2_0",
"1.0alpha7.train.255.ent3_1"
]
}
] | [
{
"id": "1.0alpha7.train.255.rel0s1.0alpha7.train.255.ent0_0.o1.0alpha7.train.255.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.255.ent0_0",
"arg2_id": "1.0alpha7.train.255.ent2_0",
"normalized": []
},
{
"id": "1.0alpha7.train.255.rel0s1.0alpha7.train.255.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.256 | 3367575 | [
{
"id": "1.0alpha7.train.256.sent",
"type": "sentence",
"text": [
"However, affinity chromatography experiments showed that Tm bound to acidic TnT with a greater affinity than to basic TnT, consistent with the significantly higher maximal binding of acidic TnT to Tm in solid phase binding assays."... | [
{
"id": "1.0alpha7.train.256.ent0_0",
"type": "protein",
"text": [
"TnT"
],
"offsets": [
[
76,
79
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.256.ent1_1",
"type": "protein",
"text": [
"TnT"
],
"offsets": [
[
... | [] | [
{
"id": "1.0alpha7.train.256.coref0",
"entity_ids": [
"1.0alpha7.train.256.ent0_0",
"1.0alpha7.train.256.ent1_1",
"1.0alpha7.train.256.ent2_2"
]
},
{
"id": "1.0alpha7.train.256.coref1",
"entity_ids": [
"1.0alpha7.train.256.ent3_0"
]
},
{
"id": "1.0alpha7.t... | [
{
"id": "1.0alpha7.train.256.rel0s1.0alpha7.train.256.ent0_0.o1.0alpha7.train.256.ent4_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.256.ent0_0",
"arg2_id": "1.0alpha7.train.256.ent4_0",
"normalized": []
},
{
"id": "1.0alpha7.train.256.rel0s1.0alpha7.train.256.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.257 | 25166232 | [
{
"id": "1.0alpha7.train.257.sent",
"type": "sentence",
"text": [
"Ca2+-Dependent Binding of Syntaxin 1a to the C2A Domain Demonstrated by 1H-15N HSQC Spectroscopy"
],
"offsets": [
[
0,
96
]
]
}
] | [
{
"id": "1.0alpha7.train.257.ent0_0",
"type": "assay",
"text": [
"1H-15N HSQC Spectroscopy"
],
"offsets": [
[
72,
96
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.257.ent1_0",
"type": "chemical",
"text": [
"Ca2+"
],
"off... | [] | [
{
"id": "1.0alpha7.train.257.coref0",
"entity_ids": [
"1.0alpha7.train.257.ent0_0"
]
},
{
"id": "1.0alpha7.train.257.coref1",
"entity_ids": [
"1.0alpha7.train.257.ent1_0"
]
},
{
"id": "1.0alpha7.train.257.coref2",
"entity_ids": [
"1.0alpha7.train.257.ent2_0"... | [
{
"id": "1.0alpha7.train.257.rel0s1.0alpha7.train.257.ent1_0.o1.0alpha7.train.257.ent3_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.257.ent1_0",
"arg2_id": "1.0alpha7.train.257.ent3_0",
"normalized": []
}
] |
1.0alpha7.train.258 | 563208 | [
{
"id": "1.0alpha7.train.258.sent",
"type": "sentence",
"text": [
"Adducin is a membrane skeleton protein originally described in human erythrocytes that promotes the binding of spectrin to actin and also binds directly to actin and bundles actin filaments."
],
"offsets": [
[
... | [
{
"id": "1.0alpha7.train.258.ent0_0",
"type": "protein-complex",
"text": [
"spectrin"
],
"offsets": [
[
111,
119
]
],
"normalized": [
{
"db_name": "interpro",
"db_id": "IPR002017"
}
]
},
{
"id": "1.0alpha7.train.25... | [] | [
{
"id": "1.0alpha7.train.258.coref0",
"entity_ids": [
"1.0alpha7.train.258.ent0_0"
]
},
{
"id": "1.0alpha7.train.258.coref1",
"entity_ids": [
"1.0alpha7.train.258.ent1_0",
"1.0alpha7.train.258.ent2_1",
"1.0alpha7.train.258.ent3_2"
]
},
{
"id": "1.0alpha7.t... | [
{
"id": "1.0alpha7.train.258.rel0s1.0alpha7.train.258.ent1_0.o1.0alpha7.train.258.ent4_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.258.ent1_0",
"arg2_id": "1.0alpha7.train.258.ent4_0",
"normalized": []
},
{
"id": "1.0alpha7.train.258.rel0s1.0alpha7.train.258.ent2_1.o1.0alpha7.train.2... |
1.0alpha7.train.259 | 6233645 | [
{
"id": "1.0alpha7.train.259.sent",
"type": "sentence",
"text": [
"In conjunction with peptide-binding and genetic studies, atomic modeling of fimbrin binding to F-actin strongly suggests that the F-actin-binding residues in the CH domain are concentrated in its C-terminal portion ( 23)."
],
... | [
{
"id": "1.0alpha7.train.259.ent0_0",
"type": "protein",
"text": [
"fimbrin"
],
"offsets": [
[
76,
83
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "5357"
},
{
"db_name": "hgnc",
"db_id": "PLS1"... | [] | [
{
"id": "1.0alpha7.train.259.coref0",
"entity_ids": [
"1.0alpha7.train.259.ent0_0"
]
},
{
"id": "1.0alpha7.train.259.coref1",
"entity_ids": [
"1.0alpha7.train.259.ent1_0",
"1.0alpha7.train.259.ent2_1"
]
},
{
"id": "1.0alpha7.train.259.coref2",
"entity_ids": ... | [
{
"id": "1.0alpha7.train.259.rel0s1.0alpha7.train.259.ent0_0.o1.0alpha7.train.259.ent4_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.259.ent0_0",
"arg2_id": "1.0alpha7.train.259.ent4_0",
"normalized": []
},
{
"id": "1.0alpha7.train.259.rel0s1.0alpha7.train.259.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.260 | 5676496 | [
{
"id": "1.0alpha7.train.260.sent",
"type": "sentence",
"text": [
"Comparison of the Ral-binding surface of Sec5 with the region of GDI that interacts with Rho family G proteins shows that the contacts between Sec5-Ral and GDI-Cdc42 are significantly different."
],
"offsets": [
[
... | [
{
"id": "1.0alpha7.train.260.ent0_0",
"type": "protein",
"text": [
"GDI"
],
"offsets": [
[
65,
68
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.260.ent1_1",
"type": "protein",
"text": [
"GDI"
],
"offsets": [
[
... | [] | [
{
"id": "1.0alpha7.train.260.coref0",
"entity_ids": [
"1.0alpha7.train.260.ent0_0",
"1.0alpha7.train.260.ent1_1"
]
},
{
"id": "1.0alpha7.train.260.coref1",
"entity_ids": [
"1.0alpha7.train.260.ent2_0",
"1.0alpha7.train.260.ent3_1"
]
},
{
"id": "1.0alpha7.t... | [
{
"id": "1.0alpha7.train.260.rel0s1.0alpha7.train.260.ent2_0.o1.0alpha7.train.260.ent4_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.260.ent2_0",
"arg2_id": "1.0alpha7.train.260.ent4_0",
"normalized": []
},
{
"id": "1.0alpha7.train.260.rel0s1.0alpha7.train.260.ent2_0.o1.0alpha7.train.2... |
1.0alpha7.train.261 | 3506818 | [
{
"id": "1.0alpha7.train.261.sent",
"type": "sentence",
"text": [
"The binding sites for Armadillo and Groucho on Tcf do not overlap, but whether or not Armadillo and Groucho bind simultaneously to Tcf is not clear."
],
"offsets": [
[
0,
148
]
]
}
] | [
{
"id": "1.0alpha7.train.261.ent0_0",
"type": "protein-family",
"text": [
"Tcf"
],
"offsets": [
[
47,
50
]
],
"normalized": [
{
"db_name": "interpro",
"db_id": "IPR024940"
}
]
},
{
"id": "1.0alpha7.train.261.ent1_1... | [] | [
{
"id": "1.0alpha7.train.261.coref0",
"entity_ids": [
"1.0alpha7.train.261.ent0_0",
"1.0alpha7.train.261.ent1_1"
]
},
{
"id": "1.0alpha7.train.261.coref1",
"entity_ids": [
"1.0alpha7.train.261.ent2_0",
"1.0alpha7.train.261.ent3_1"
]
},
{
"id": "1.0alpha7.t... | [
{
"id": "1.0alpha7.train.261.rel0s1.0alpha7.train.261.ent0_0.o1.0alpha7.train.261.ent4_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.261.ent0_0",
"arg2_id": "1.0alpha7.train.261.ent4_0",
"normalized": []
},
{
"id": "1.0alpha7.train.261.rel0s1.0alpha7.train.261.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.262 | 4281828 | [
{
"id": "1.0alpha7.train.262.sent",
"type": "sentence",
"text": [
"Specific binding of Sp1 and Smad3 was inhibited with an excess of 100x unlabeled oligonucleotide ( Competitor)."
],
"offsets": [
[
0,
111
]
]
}
] | [
{
"id": "1.0alpha7.train.262.ent0_0",
"type": "protein",
"text": [
"Sp1"
],
"offsets": [
[
20,
23
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "6667"
},
{
"db_name": "hgnc",
"db_id": "SP1"
... | [] | [
{
"id": "1.0alpha7.train.262.coref0",
"entity_ids": [
"1.0alpha7.train.262.ent0_0"
]
},
{
"id": "1.0alpha7.train.262.coref1",
"entity_ids": [
"1.0alpha7.train.262.ent1_0"
]
}
] | [
{
"id": "1.0alpha7.train.262.rel0s1.0alpha7.train.262.ent0_0.o1.0alpha7.train.262.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.262.ent0_0",
"arg2_id": "1.0alpha7.train.262.ent1_0",
"normalized": []
}
] |
1.0alpha7.train.263 | 3533947 | [
{
"id": "1.0alpha7.train.263.sent",
"type": "sentence",
"text": [
"This indicates that the binding of GSK-3beta to Axin is essential for its activity to degrade beta-catenin, consistent with the observation that AxindeltaGSK-3beta does not enhance the phosphorylation of beta-catenin even in the pr... | [
{
"id": "1.0alpha7.train.263.ent0_0",
"type": "protein",
"text": [
"Axin"
],
"offsets": [
[
48,
52
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "8312"
},
{
"db_name": "hgnc",
"db_id": "AXIN1"
... | [] | [
{
"id": "1.0alpha7.train.263.coref0",
"entity_ids": [
"1.0alpha7.train.263.ent0_0"
]
},
{
"id": "1.0alpha7.train.263.coref1",
"entity_ids": [
"1.0alpha7.train.263.ent1_0"
]
},
{
"id": "1.0alpha7.train.263.coref2",
"entity_ids": [
"1.0alpha7.train.263.ent2_0"... | [
{
"id": "1.0alpha7.train.263.rel0s1.0alpha7.train.263.ent0_0.o1.0alpha7.train.263.ent6_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.263.ent0_0",
"arg2_id": "1.0alpha7.train.263.ent6_0",
"normalized": []
}
] |
1.0alpha7.train.264 | 25751449 | [
{
"id": "1.0alpha7.train.264.sent",
"type": "sentence",
"text": [
"N.N. Dewji and S.J. Singer, Specific transcellular binding between membrane proteins crucial to Alzheimer disease."
],
"offsets": [
[
0,
114
]
]
}
] | [] | [] | [] | [] |
1.0alpha7.train.265 | 16335607 | [
{
"id": "1.0alpha7.train.265.sent",
"type": "sentence",
"text": [
"We tested seven mAbs derived from an HIV-2-infected human for their ability to inhibit SIVmac239 gp120 binding to CCR5rh in HEK293 cells in the presence and absence of sCD4."
],
"offsets": [
[
0,
173
... | [
{
"id": "1.0alpha7.train.265.ent0_0",
"type": "reagent",
"text": [
"mAbs"
],
"offsets": [
[
16,
20
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.265.ent1_0",
"type": "protein",
"text": [
"CCR5rh"
],
"offsets": [
[
... | [] | [
{
"id": "1.0alpha7.train.265.coref0",
"entity_ids": [
"1.0alpha7.train.265.ent0_0"
]
},
{
"id": "1.0alpha7.train.265.coref1",
"entity_ids": [
"1.0alpha7.train.265.ent1_0"
]
},
{
"id": "1.0alpha7.train.265.coref2",
"entity_ids": [
"1.0alpha7.train.265.ent2_0"... | [
{
"id": "1.0alpha7.train.265.rel0s1.0alpha7.train.265.ent1_0.o1.0alpha7.train.265.ent3_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.265.ent1_0",
"arg2_id": "1.0alpha7.train.265.ent3_0",
"normalized": []
}
] |
1.0alpha7.train.266 | 3181409 | [
{
"id": "1.0alpha7.train.266.sent",
"type": "sentence",
"text": [
"After extensive washing, the amount of MyD118/Gadd45 protein bound to PCNA was assessed using either MyD118- or Gadd45-specific antibodies, which, in turn, were reacted with HRP-coupled secondary antibody."
],
"offsets": [
... | [
{
"id": "1.0alpha7.train.266.ent0_0",
"type": "protein",
"text": [
"PCNA"
],
"offsets": [
[
70,
74
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "5111"
},
{
"db_name": "hgnc",
"db_id": "PCNA"
... | [] | [
{
"id": "1.0alpha7.train.266.coref0",
"entity_ids": [
"1.0alpha7.train.266.ent0_0"
]
},
{
"id": "1.0alpha7.train.266.coref1",
"entity_ids": [
"1.0alpha7.train.266.ent1_0",
"1.0alpha7.train.266.ent2_1"
]
},
{
"id": "1.0alpha7.train.266.coref2",
"entity_ids": ... | [
{
"id": "1.0alpha7.train.266.rel0s1.0alpha7.train.266.ent0_0.o1.0alpha7.train.266.ent4_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.266.ent0_0",
"arg2_id": "1.0alpha7.train.266.ent4_0",
"normalized": []
},
{
"id": "1.0alpha7.train.266.rel0s1.0alpha7.train.266.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.267 | 15268425 | [
{
"id": "1.0alpha7.train.267.sent",
"type": "sentence",
"text": [
"Given the observation that CRT binds to SL structures with GC-rich stems (7, 16, 24, 27), we searched for the secondary structures with GC-rich stems within the C/EBPα mRNA and found two possible SL organizations containing GC-rich... | [
{
"id": "1.0alpha7.train.267.ent0_0",
"type": "DNA",
"text": [
"SL structures"
],
"offsets": [
[
40,
53
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.267.ent1_0",
"type": "DNA",
"text": [
"GC-rich stems"
],
"offsets": [
... | [] | [
{
"id": "1.0alpha7.train.267.coref0",
"entity_ids": [
"1.0alpha7.train.267.ent0_0"
]
},
{
"id": "1.0alpha7.train.267.coref1",
"entity_ids": [
"1.0alpha7.train.267.ent1_0",
"1.0alpha7.train.267.ent2_1"
]
},
{
"id": "1.0alpha7.train.267.coref2",
"entity_ids": ... | [] |
1.0alpha7.train.268 | 25166292 | [
{
"id": "1.0alpha7.train.268.sent",
"type": "sentence",
"text": [
"These observations strongly suggest that electrostatic interactions provide a main driving force for the Ca2+-dependent binding of the C2A domain to syntaxin."
],
"offsets": [
[
0,
158
]
]
... | [
{
"id": "1.0alpha7.train.268.ent0_0",
"type": "protein-family",
"text": [
"syntaxin"
],
"offsets": [
[
149,
157
]
],
"normalized": [
{
"db_name": "interpro",
"db_id": "IPR006011"
}
]
},
{
"id": "1.0alpha7.train.268... | [] | [
{
"id": "1.0alpha7.train.268.coref0",
"entity_ids": [
"1.0alpha7.train.268.ent0_0"
]
},
{
"id": "1.0alpha7.train.268.coref1",
"entity_ids": [
"1.0alpha7.train.268.ent1_0"
]
},
{
"id": "1.0alpha7.train.268.coref2",
"entity_ids": [
"1.0alpha7.train.268.ent2_0"... | [
{
"id": "1.0alpha7.train.268.rel0s1.0alpha7.train.268.ent0_0.o1.0alpha7.train.268.ent2_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.268.ent0_0",
"arg2_id": "1.0alpha7.train.268.ent2_0",
"normalized": []
}
] |
1.0alpha7.train.269 | 20479913 | [
{
"id": "1.0alpha7.train.269.sent",
"type": "sentence",
"text": [
"In this report, we show that AlF-C1 and AlF-C2 bind directly to Orc1, a subunit of ORC, and discuss that in mammalian cells, sequence-specific DNA-binding proteins might be involved in recruiting ORC to regulate replication initiat... | [
{
"id": "1.0alpha7.train.269.ent0_0",
"type": "protein",
"text": [
"AlF-C2"
],
"offsets": [
[
40,
46
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.269.ent1_0",
"type": "protein",
"text": [
"AlF-C1"
],
"offsets": [
... | [] | [
{
"id": "1.0alpha7.train.269.coref0",
"entity_ids": [
"1.0alpha7.train.269.ent0_0"
]
},
{
"id": "1.0alpha7.train.269.coref1",
"entity_ids": [
"1.0alpha7.train.269.ent1_0"
]
},
{
"id": "1.0alpha7.train.269.coref2",
"entity_ids": [
"1.0alpha7.train.269.ent2_0"... | [
{
"id": "1.0alpha7.train.269.rel0s1.0alpha7.train.269.ent1_0.o1.0alpha7.train.269.ent5_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.269.ent1_0",
"arg2_id": "1.0alpha7.train.269.ent5_0",
"normalized": []
},
{
"id": "1.0alpha7.train.269.rel1s1.0alpha7.train.269.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.270 | 15937374 | [
{
"id": "1.0alpha7.train.270.sent",
"type": "sentence",
"text": [
"It has been shown that APC makes a complex with beta-catenin and that the phosphorylation of APC by GSK-3beta increases the binding of APC to beta-catenin ( 37)."
],
"offsets": [
[
0,
161
]
]... | [
{
"id": "1.0alpha7.train.270.ent0_0",
"type": "protein",
"text": [
"APC"
],
"offsets": [
[
23,
26
]
],
"normalized": [
{
"db_name": "NCBI gene",
"db_id": "324"
},
{
"db_name": "hgnc",
"db_id": "APC"
... | [] | [
{
"id": "1.0alpha7.train.270.coref0",
"entity_ids": [
"1.0alpha7.train.270.ent0_0",
"1.0alpha7.train.270.ent1_1",
"1.0alpha7.train.270.ent2_2"
]
},
{
"id": "1.0alpha7.train.270.coref1",
"entity_ids": [
"1.0alpha7.train.270.ent3_0"
]
},
{
"id": "1.0alpha7.t... | [
{
"id": "1.0alpha7.train.270.rel0s1.0alpha7.train.270.ent0_0.o1.0alpha7.train.270.ent4_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.270.ent0_0",
"arg2_id": "1.0alpha7.train.270.ent4_0",
"normalized": []
},
{
"id": "1.0alpha7.train.270.rel0s1.0alpha7.train.270.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.271 | 3129207 | [
{
"id": "1.0alpha7.train.271.sent",
"type": "sentence",
"text": [
"Interestingly, dTAFII110 also bound GST-IIAτ more abundantly than it bound to GST-αβ (Fig.4 C, lane 4)."
],
"offsets": [
[
0,
103
]
]
}
] | [
{
"id": "1.0alpha7.train.271.ent0_0",
"type": "protein",
"text": [
"dTAFII110"
],
"offsets": [
[
15,
24
]
],
"normalized": [
{
"db_name": "uniprot",
"db_id": "B7Z060"
}
]
},
{
"id": "1.0alpha7.train.271.ent1_0",
... | [] | [
{
"id": "1.0alpha7.train.271.coref0",
"entity_ids": [
"1.0alpha7.train.271.ent0_0"
]
},
{
"id": "1.0alpha7.train.271.coref1",
"entity_ids": [
"1.0alpha7.train.271.ent1_0"
]
},
{
"id": "1.0alpha7.train.271.coref2",
"entity_ids": [
"1.0alpha7.train.271.ent2_0"... | [
{
"id": "1.0alpha7.train.271.rel0s1.0alpha7.train.271.ent0_0.o1.0alpha7.train.271.ent5_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.271.ent0_0",
"arg2_id": "1.0alpha7.train.271.ent5_0",
"normalized": []
},
{
"id": "1.0alpha7.train.271.rel1s1.0alpha7.train.271.ent0_0.o1.0alpha7.train.2... |
1.0alpha7.train.272 | 19640896 | [
{
"id": "1.0alpha7.train.272.sent",
"type": "sentence",
"text": [
"Hes6 binds to an Enhancer of Split E box and mediates transcriptional repression"
],
"offsets": [
[
0,
80
]
]
}
] | [
{
"id": "1.0alpha7.train.272.ent0_0",
"type": "DNA",
"text": [
"Split E box"
],
"offsets": [
[
29,
40
]
],
"normalized": []
},
{
"id": "1.0alpha7.train.272.ent1_0",
"type": "protein",
"text": [
"Hes6"
],
"offsets": [
[... | [] | [
{
"id": "1.0alpha7.train.272.coref0",
"entity_ids": [
"1.0alpha7.train.272.ent0_0"
]
},
{
"id": "1.0alpha7.train.272.coref1",
"entity_ids": [
"1.0alpha7.train.272.ent1_0"
]
}
] | [
{
"id": "1.0alpha7.train.272.rel0s1.0alpha7.train.272.ent0_0.o1.0alpha7.train.272.ent1_0",
"type": "bind",
"arg1_id": "1.0alpha7.train.272.ent0_0",
"arg2_id": "1.0alpha7.train.272.ent1_0",
"normalized": []
}
] |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.