Daily Papers

In this work, we propose and study a double Kondo lattice model which hosts robust superconductivity. The system consists of two identical Kondo lattice model, each with Kondo coupling J_K within each layer, while the localized spin moments are coupled together via an inter-layer on-site antiferromagnetic spin coupling J_perp. We consider the strong J_perp limit, wherein the local moments tend to form rung singlets and are thus gapped. However, the Kondo coupling J_K transmits the inter-layer entanglement between the local moments to the itinerant electrons. Consequently, the itinerant electrons experience a strong inter-layer antiferromangetic spin coupling and form strong inter-layer pairing, which is confirmed through numerical simulation in one dimensional system. Experimentally, the J_K rightarrow -infty limits of the model describes the recently found bilayer nickelate La_3Ni_2O_7, while the J_K>0 side can be realized in tetralayer optical lattice of cold atoms. Two extreme limits, J_K rightarrow -infty and J_K rightarrow +infty limit are shown to be simplified to a bilayer type II t-J model and a bilayer one-orbital t-J model, respectively. Thus, our double Kondo lattice model offers a unified framework for nickelate superconductor and tetralayer optical lattice quantum simulator upon changing the sign of J_K. We highlight both the qualitative similarity and the quantitative difference in the two sides of J_K. Finally, we discuss the possibility of a symmetric Kondo breakdown transition in the model with a symmetric pseudogap metal corresponding to the usual heavy Fermi liquid.

Despite widespread deployment of Large Language Models, systematic evaluation of instruction-following capabilities remains challenging. While comprehensive benchmarks exist, focused assessments that quickly diagnose specific instruction adherence patterns are valuable. As newer models may be trained on existing benchmarks, novel evaluation approaches are needed to assess genuine capabilities rather than memorized performance. This paper presents a streamlined evaluation framework using twenty carefully designed prompts to assess LLM instruction-following across diverse task categories. We demonstrate this framework through a large-scale empirical study conducted on October 14, 2025, testing 256 verified working models from 331 available via OpenRouter. To ensure methodological rigor and prevent selection bias, we first verified each model's basic functionality before inclusion. Unlike large-scale benchmarks requiring extensive computational resources, our approach offers a practical diagnostic tool researchers and practitioners can readily apply. Our methodology builds upon verifiable instructions while introducing a compact test suite balancing comprehensiveness with efficiency. Each prompt targets distinct aspects of instruction following, including format compliance, content constraints, logical sequencing, and multi-step task execution. We evaluate models from major providers (OpenAI, Anthropic, Google, Meta, Mistral) and emerging implementations (Qwen, DeepSeek, community models), providing comparative performance analysis. Our findings reveal consistent failure modes and identify specific instruction types posing particular challenges. This work contributes both a practical evaluation tool and one of the most comprehensive empirical analyses of instruction-following capabilities across the contemporary LLM landscape.

The inference demand for LLMs has skyrocketed in recent months, and serving models with low latencies remains challenging due to the quadratic input length complexity of the attention layers. In this work, we investigate the effect of dropping MLP and attention layers at inference time on the performance of Llama-v2 models. We find that dropping dreeper attention layers only marginally decreases performance but leads to the best speedups alongside dropping entire layers. For example, removing 33\% of attention layers in a 13B Llama2 model results in a 1.8\% drop in average performance over the OpenLLM benchmark. We also observe that skipping layers except the latter layers reduces performances for more layers skipped, except for skipping the attention layers.

Conflict scholars have used rule-based approaches to extract information about political violence from news reports and texts. Recent Natural Language Processing developments move beyond rigid rule-based approaches. We review our recent ConfliBERT language model (Hu et al. 2022) to process political and violence related texts. The model can be used to extract actor and action classifications from texts about political conflict. When fine-tuned, results show that ConfliBERT has superior performance in accuracy, precision and recall over other large language models (LLM) like Google's Gemma 2 (9B), Meta's Llama 3.1 (7B), and Alibaba's Qwen 2.5 (14B) within its relevant domains. It is also hundreds of times faster than these more generalist LLMs. These results are illustrated using texts from the BBC, re3d, and the Global Terrorism Dataset (GTD).

Reinforcement learning (RL) promises to expand the capabilities of language models, but it is unclear if current RL techniques promote the discovery of novel behaviors, or simply sharpen those already present in the base model. In this paper, we investigate the value of deliberate exploration -- explicitly incentivizing the model to discover novel and diverse behaviors -- and aim to understand how the knowledge in pre-trained models can guide this search. Our main finding is that exploration with a simple, principled, representation-based bonus derived from the pre-trained language model's hidden states significantly improves diversity and pass@k rates -- both for post-training, and in a novel inference-time scaling setting we introduce. For inference-time, exploration with representation-based diversity improves efficiency, consistently improving pass@k rates across a variety of models and reasoning tasks. For example, for Qwen-2.5-14b-Instruct we obtain over 50% improvement in verifier efficiency on almost all tasks. For post-training, we show that integrating this exploration strategy into an RL pipeline improves reasoning performance over that of the initial model and over standard RL post-training. For example, on AIME 2024, our post-trained Qwen-2.5-7b-Instruct's pass@80 matches the pass@256 of GRPO on the same model, demonstrating a 3x improvement in test-time sample efficiency. Overall, our findings suggest that deliberate exploration -- with the right notion of diversity -- is a practical path toward discovery of new behaviors beyond sharpening.

We use new cosmic microwave background (CMB) primary temperature and polarization anisotropy measurements from the Atacama Cosmology Telescope (ACT) Data Release 6 (DR6) to test foundational assumptions of the standard cosmological model and set constraints on extensions to it. We derive constraints from the ACT DR6 power spectra alone, as well as in combination with legacy data from Planck. To break geometric degeneracies, we include ACT and Planck CMB lensing data and baryon acoustic oscillation data from DESI Year-1, and further add supernovae measurements from Pantheon+ for models that affect the late-time expansion history. We verify the near-scale-invariance (running of the spectral index d n_s/dln k = 0.0062 pm 0.0052) and adiabaticity of the primordial perturbations. Neutrino properties are consistent with Standard Model predictions: we find no evidence for new light, relativistic species that are free-streaming (N_{rm eff} = 2.86 pm 0.13, which combined with external BBN data becomes N_{rm eff} = 2.89 pm 0.11), for non-zero neutrino masses (sum m_nu < 0.082 eV at 95% CL), or for neutrino self-interactions. We also find no evidence for self-interacting dark radiation (N_{rm idr} < 0.134), early-universe variation of fundamental constants, early dark energy, primordial magnetic fields, or modified recombination. Our data are consistent with standard BBN, the FIRAS-inferred CMB temperature, a dark matter component that is collisionless and with only a small fraction allowed as axion-like particles, a cosmological constant, and the late-time growth rate predicted by general relativity. We find no statistically significant preference for a departure from the baseline LambdaCDM model. In general, models introduced to increase the Hubble constant or to decrease the amplitude of density fluctuations inferred from the primary CMB are not favored by our data.

Recent work in language modeling has raised the possibility of self-improvement, where a language models evaluates and refines its own generations to achieve higher performance without external feedback. It is impossible for this self-improvement to create information that is not already in the model, so why should we expect that this will lead to improved capabilities? We offer a new perspective on the capabilities of self-improvement through a lens we refer to as sharpening. Motivated by the observation that language models are often better at verifying response quality than they are at generating correct responses, we formalize self-improvement as using the model itself as a verifier during post-training in order to ``sharpen'' the model to one placing large mass on high-quality sequences, thereby amortizing the expensive inference-time computation of generating good sequences. We begin by introducing a new statistical framework for sharpening in which the learner aims to sharpen a pre-trained base policy via sample access, and establish fundamental limits. Then we analyze two natural families of self-improvement algorithms based on SFT and RLHF. We find that (i) the SFT-based approach is minimax optimal whenever the initial model has sufficient coverage, but (ii) the RLHF-based approach can improve over SFT-based self-improvement by leveraging online exploration, bypassing the need for coverage. Finally, we empirically validate the sharpening mechanism via inference-time and amortization experiments. We view these findings as a starting point toward a foundational understanding that can guide the design and evaluation of self-improvement algorithms.

The magnetic phase diagram at zero external field of an ensemble of dipoles with uniaxial anisotropy on a FCC lattice is investigated from tempered Monte Carlo simulations. The uniaxial anisotropy is characterized by a random distribution of easy axes and its magnitude lambda_u is the driving force of disorder and consequently frustration. The phase diagram, separating the paramagnetic, ferromagnetic, quasi long range ordered ferromagnetic and spin-glass regions is thus considered in the temperature, lambda_u plane. This system is aimed at modeling the magnetic phase diagram of supracrystals of magnetic nanoparticles.

Machine-learned force fields have transformed the atomistic modelling of materials by enabling simulations of ab initio quality on unprecedented time and length scales. However, they are currently limited by: (i) the significant computational and human effort that must go into development and validation of potentials for each particular system of interest; and (ii) a general lack of transferability from one chemical system to the next. Here, using the state-of-the-art MACE architecture we introduce a single general-purpose ML model, trained on a public database of 150k inorganic crystals, that is capable of running stable molecular dynamics on molecules and materials. We demonstrate the power of the MACE-MP-0 model -- and its qualitative and at times quantitative accuracy -- on a diverse set problems in the physical sciences, including the properties of solids, liquids, gases, and chemical reactions. The model can be applied out of the box and as a starting or "foundation model" for any atomistic system of interest and is thus a step towards democratising the revolution of ML force fields by lowering the barriers to entry.

Background: Electronic Health Records hold detailed longitudinal information about each patient's health status and general clinical history, a large portion of which is stored within the unstructured text. Existing approaches focus mostly on structured data and a subset of single-domain outcomes. We explore how temporal modelling of patients from free text and structured data, using deep generative transformers can be used to forecast a wide range of future disorders, substances, procedures or findings. Methods: We present Foresight, a novel transformer-based pipeline that uses named entity recognition and linking tools to convert document text into structured, coded concepts, followed by providing probabilistic forecasts for future medical events such as disorders, substances, procedures and findings. We processed the entire free-text portion from three different hospital datasets totalling 811336 patients covering both physical and mental health. Findings: On tests in two UK hospitals (King's College Hospital, South London and Maudsley) and the US MIMIC-III dataset precision@10 0.68, 0.76 and 0.88 was achieved for forecasting the next disorder in a patient timeline, while precision@10 of 0.80, 0.81 and 0.91 was achieved for forecasting the next biomedical concept. Foresight was also validated on 34 synthetic patient timelines by five clinicians and achieved relevancy of 97% for the top forecasted candidate disorder. As a generative model, it can forecast follow-on biomedical concepts for as many steps as required. Interpretation: Foresight is a general-purpose model for biomedical concept modelling that can be used for real-world risk forecasting, virtual trials and clinical research to study the progression of disorders, simulate interventions and counterfactuals, and educational purposes.

Automated speaker identification (SID) is a crucial step for the personalization of a wide range of speech-enabled services. Typical SID systems use a symmetric enrollment-verification framework with a single model to derive embeddings both offline for voice profiles extracted from enrollment utterances, and online from runtime utterances. Due to the distinct circumstances of enrollment and runtime, such as different computation and latency constraints, several applications would benefit from an asymmetric enrollment-verification framework that uses different models for enrollment and runtime embedding generation. To support this asymmetric SID where each of the two models can be updated independently, we propose using a lightweight neural network to map the embeddings from the two independent models to a shared speaker embedding space. Our results show that this approach significantly outperforms cosine scoring in a shared speaker logit space for models that were trained with a contrastive loss on large datasets with many speaker identities. This proposed Neural Embedding Speaker Space Alignment (NESSA) combined with an asymmetric update of only one of the models delivers at least 60% of the performance gain achieved by updating both models in the standard symmetric SID approach.

We systematically study a wide variety of image-based generative models spanning semantically-diverse datasets to understand and improve the feature extractors and metrics used to evaluate them. Using best practices in psychophysics, we measure human perception of image realism for generated samples by conducting the largest experiment evaluating generative models to date, and find that no existing metric strongly correlates with human evaluations. Comparing to 16 modern metrics for evaluating the overall performance, fidelity, diversity, and memorization of generative models, we find that the state-of-the-art perceptual realism of diffusion models as judged by humans is not reflected in commonly reported metrics such as FID. This discrepancy is not explained by diversity in generated samples, though one cause is over-reliance on Inception-V3. We address these flaws through a study of alternative self-supervised feature extractors, find that the semantic information encoded by individual networks strongly depends on their training procedure, and show that DINOv2-ViT-L/14 allows for much richer evaluation of generative models. Next, we investigate data memorization, and find that generative models do memorize training examples on simple, smaller datasets like CIFAR10, but not necessarily on more complex datasets like ImageNet. However, our experiments show that current metrics do not properly detect memorization; none in the literature is able to separate memorization from other phenomena such as underfitting or mode shrinkage. To facilitate further development of generative models and their evaluation we release all generated image datasets, human evaluation data, and a modular library to compute 16 common metrics for 8 different encoders at https://github.com/layer6ai-labs/dgm-eval.

Language models demonstrate both quantitative improvement and new qualitative capabilities with increasing scale. Despite their potentially transformative impact, these new capabilities are as yet poorly characterized. In order to inform future research, prepare for disruptive new model capabilities, and ameliorate socially harmful effects, it is vital that we understand the present and near-future capabilities and limitations of language models. To address this challenge, we introduce the Beyond the Imitation Game benchmark (BIG-bench). BIG-bench currently consists of 204 tasks, contributed by 442 authors across 132 institutions. Task topics are diverse, drawing problems from linguistics, childhood development, math, common-sense reasoning, biology, physics, social bias, software development, and beyond. BIG-bench focuses on tasks that are believed to be beyond the capabilities of current language models. We evaluate the behavior of OpenAI's GPT models, Google-internal dense transformer architectures, and Switch-style sparse transformers on BIG-bench, across model sizes spanning millions to hundreds of billions of parameters. In addition, a team of human expert raters performed all tasks in order to provide a strong baseline. Findings include: model performance and calibration both improve with scale, but are poor in absolute terms (and when compared with rater performance); performance is remarkably similar across model classes, though with benefits from sparsity; tasks that improve gradually and predictably commonly involve a large knowledge or memorization component, whereas tasks that exhibit "breakthrough" behavior at a critical scale often involve multiple steps or components, or brittle metrics; social bias typically increases with scale in settings with ambiguous context, but this can be improved with prompting.

Modern astronomical surveys, such as the Euclid mission, produce high-dimensional, multi-modal data sets that include imaging and spectroscopic information for millions of galaxies. These data serve as an ideal benchmark for large, pre-trained multi-modal models, which can leverage vast amounts of unlabelled data. In this work, we present the first exploration of Euclid data with AstroPT, an autoregressive multi-modal foundation model trained on approximately 300 000 optical and infrared Euclid images and spectral energy distributions (SEDs) from the first Euclid Quick Data Release. We compare self-supervised pre-training with baseline fully supervised training across several tasks: galaxy morphology classification; redshift estimation; similarity searches; and outlier detection. Our results show that: (a) AstroPT embeddings are highly informative, correlating with morphology and effectively isolating outliers; (b) including infrared data helps to isolate stars, but degrades the identification of edge-on galaxies, which are better captured by optical images; (c) simple fine-tuning of these embeddings for photometric redshift and stellar mass estimation outperforms a fully supervised approach, even when using only 1% of the training labels; and (d) incorporating SED data into AstroPT via a straightforward multi-modal token-chaining method improves photo-z predictions, and allow us to identify potentially more interesting anomalies (such as ringed or interacting galaxies) compared to a model pre-trained solely on imaging data.

We introduce DeepSeek-V3.2, a model that harmonizes high computational efficiency with superior reasoning and agent performance. The key technical breakthroughs of DeepSeek-V3.2 are as follows: (1) DeepSeek Sparse Attention (DSA): We introduce DSA, an efficient attention mechanism that substantially reduces computational complexity while preserving model performance in long-context scenarios. (2) Scalable Reinforcement Learning Framework: By implementing a robust reinforcement learning protocol and scaling post-training compute, DeepSeek-V3.2 performs comparably to GPT-5. Notably, our high-compute variant, DeepSeek-V3.2-Speciale, surpasses GPT-5 and exhibits reasoning proficiency on par with Gemini-3.0-Pro, achieving gold-medal performance in both the 2025 International Mathematical Olympiad (IMO) and the International Olympiad in Informatics (IOI). (3) Large-Scale Agentic Task Synthesis Pipeline: To integrate reasoning into tool-use scenarios, we developed a novel synthesis pipeline that systematically generates training data at scale. This methodology facilitates scalable agentic post-training, yielding substantial improvements in generalization and instruction-following robustness within complex, interactive environments.

Retrieval-augmented generation (RAG) has gained traction as a powerful approach for enhancing language models by integrating external knowledge sources. However, RAG introduces challenges such as retrieval latency, potential errors in document selection, and increased system complexity. With the advent of large language models (LLMs) featuring significantly extended context windows, this paper proposes an alternative paradigm, cache-augmented generation (CAG) that bypasses real-time retrieval. Our method involves preloading all relevant resources, especially when the documents or knowledge for retrieval are of a limited and manageable size, into the LLM's extended context and caching its runtime parameters. During inference, the model utilizes these preloaded parameters to answer queries without additional retrieval steps. Comparative analyses reveal that CAG eliminates retrieval latency and minimizes retrieval errors while maintaining context relevance. Performance evaluations across multiple benchmarks highlight scenarios where long-context LLMs either outperform or complement traditional RAG pipelines. These findings suggest that, for certain applications, particularly those with a constrained knowledge base, CAG provide a streamlined and efficient alternative to RAG, achieving comparable or superior results with reduced complexity.

A dynamical model based on a phenomenological charm quark-nucleon(c-N) potential v_{cN} and the Pomeron-exchange mechanism is constructed to investigate the J/Psi photo-production on the nucleon from threshold to invariant mass W=300 GeV. The J/Psi-N potential,V_{J/Psi N}(r),is constructed by folding v_{cN} into the wavefunction Phi_{J/Psi}(cc) of J/Psi within a Constituent Quark Model(CQM) of Ref.[43]. A photo-production amplitude is also generated by v_{cN} by a cc-loop integration over the gammarightarrow cc vertex function and Phi_{J/Psi}(cc). No commonly used Vector Meson Dominance assumption is used to define this photo-production amplitude which is needed to describe the data near the threshold. The potential v_{cN}(r) is parameterized in a form such that the predicted V_{J/Psi N}(r) at large distances has the same Yukawa potential form extracted from a Lattice QCD(LQCD) calculation of Ref.[18]. The parameters of v_{cN} are determined by fitting the total cross section data of JLab by performing calculations that include J/Psi-N final state interactions(FSI). The resulting differential cross sections are found in good agreements with the data. It is shown that the FSI effects dominate the cross section in the very near threshold region, allowing for sensitive testing of the predicted J/Psi-N scattering amplitudes. By imposing the constraints of J/Psi-N potential extracted from the LQCD calculation, we have obtained three J/Psi-N potentials which fit the JLab data equally well. The resulting J/Psi-N scattering lengths are in the range of a=(-0.05 fm sim -0.25 fm). With the determined v_{cN}(r) and the wavefunctions generated from the same CQM, the constructed model is used to predict the cross sections of photo-production of eta_c(1S) and Psi(2S) mesons for future experimental tests.

Identifying how much a model {p}_{theta}(Y|X) knows about the stochastic real-world process p(Y|X) it was trained on is important to ensure it avoids producing incorrect or "hallucinated" answers or taking unsafe actions. But this is difficult for generative models because probabilistic predictions do not distinguish between per-response noise (aleatoric uncertainty) and lack of knowledge about the process (epistemic uncertainty), and existing epistemic uncertainty quantification techniques tend to be overconfident when the model underfits. We propose a general strategy for teaching a model to both approximate p(Y|X) and also estimate the remaining gaps between {p}_{theta}(Y|X) and p(Y|X): train it to predict pairs of independent responses drawn from the true conditional distribution, allow it to "cheat" by observing one response while predicting the other, then measure how much it cheats. Remarkably, we prove that being good at cheating (i.e. cheating whenever it improves your prediction) is equivalent to being second-order calibrated, a principled extension of ordinary calibration that allows us to construct provably-correct frequentist confidence intervals for p(Y|X) and detect incorrect responses with high probability. We demonstrate empirically that our approach accurately estimates how much models don't know across ambiguous image classification, (synthetic) language modeling, and partially-observable navigation tasks, outperforming existing techniques.

Reconstructing dynamic assets from video data is central to many in computer vision and graphics tasks. Existing 4D reconstruction approaches are limited by category-specific models or slow optimization-based methods. Inspired by the recent Large Reconstruction Model (LRM), we present the Large Interpolation Model (LIM), a transformer-based feed-forward solution, guided by a novel causal consistency loss, for interpolating implicit 3D representations across time. Given implicit 3D representations at times t_0 and t_1, LIM produces a deformed shape at any continuous time tin[t_0,t_1], delivering high-quality interpolated frames in seconds. Furthermore, LIM allows explicit mesh tracking across time, producing a consistently uv-textured mesh sequence ready for integration into existing production pipelines. We also use LIM, in conjunction with a diffusion-based multiview generator, to produce dynamic 4D reconstructions from monocular videos. We evaluate LIM on various dynamic datasets, benchmarking against image-space interpolation methods (e.g., FiLM) and direct triplane linear interpolation, and demonstrate clear advantages. In summary, LIM is the first feed-forward model capable of high-speed tracked 4D asset reconstruction across diverse categories.

We propose Diffusion Inference-Time T-Optimization (DITTO), a general-purpose frame-work for controlling pre-trained text-to-music diffusion models at inference-time via optimizing initial noise latents. Our method can be used to optimize through any differentiable feature matching loss to achieve a target (stylized) output and leverages gradient checkpointing for memory efficiency. We demonstrate a surprisingly wide-range of applications for music generation including inpainting, outpainting, and looping as well as intensity, melody, and musical structure control - all without ever fine-tuning the underlying model. When we compare our approach against related training, guidance, and optimization-based methods, we find DITTO achieves state-of-the-art performance on nearly all tasks, including outperforming comparable approaches on controllability, audio quality, and computational efficiency, thus opening the door for high-quality, flexible, training-free control of diffusion models. Sound examples can be found at https://DITTO-Music.github.io/web/.

In this work, we aim to estimate the stellar parameters of the primary (Aa) by performing asteroseismic analysis on its period-spacing pattern. We use the C-3PO neural network to perform asteroseismic modelling of the g-mode period-spacing pattern of Aa, discussing the interplay of this information with external constraints from spectroscopy (T_{rm eff} and log(g)) and eclipse modelling (R). To estimate the level of uncertainty due to different frequency extraction and pattern identification processes, we consider four different variations on the period-spacing patterns. To better understand the correlations between and the uncertainty structure of our parameter estimates, we also employed a classical, parameter-based MCMC grid search on four different stellar grids. The best-fitting, externally constrained model to the period-spacing pattern arrives at estimates of the stellar properties for Aa of: M=1.51 pm 0.05 M_odot, X_c =0.43 pm 0.04, R=1.66 pm 0.1 R_odot, f_{rm ov}=0.010, Omega_c=1.58 pm 0.01 d^{-1} with rigid rotation to within the measurement errors, log(T_{rm eff})=3.856 pm 0.008 dex, log(g)=4.18 pm 0.04 dex, and log(L)=0.809 pm 0.005 dex, which agree well with previous measurements from eclipse modelling, spectroscopy, and the Gaia DR3 luminosity. We find that the near-core properties of the best-fitting asteroseismic models are consistent with external constraints from eclipse modelling and spectroscopy. Aa appears to be a typical example of a gamma Dor star, fitting well within existing populations. We find that Aa is quasi-rigidly rotating to within the uncertainties, and note that the asteroseismic age estimate for Aa (1100 pm 100 Myr) is considerably older than the young (35 Myr) age implied by previous isochrone fits to the B binary in the literature. Our MCMC parameter-based grid-search agrees well with our pattern-modelling approach.

Objective: To determine if a realistic, but computationally efficient model of the electrocardiogram can be used to pre-train a deep neural network (DNN) with a wide range of morphologies and abnormalities specific to a given condition - T-wave Alternans (TWA) as a result of Post-Traumatic Stress Disorder, or PTSD - and significantly boost performance on a small database of rare individuals. Approach: Using a previously validated artificial ECG model, we generated 180,000 artificial ECGs with or without significant TWA, with varying heart rate, breathing rate, TWA amplitude, and ECG morphology. A DNN, trained on over 70,000 patients to classify 25 different rhythms, was modified the output layer to a binary class (TWA or no-TWA, or equivalently, PTSD or no-PTSD), and transfer learning was performed on the artificial ECG. In a final transfer learning step, the DNN was trained and cross-validated on ECG from 12 PTSD and 24 controls for all combinations of using the three databases. Main results: The best performing approach (AUROC = 0.77, Accuracy = 0.72, F1-score = 0.64) was found by performing both transfer learning steps, using the pre-trained arrhythmia DNN, the artificial data and the real PTSD-related ECG data. Removing the artificial data from training led to the largest drop in performance. Removing the arrhythmia data from training provided a modest, but significant, drop in performance. The final model showed no significant drop in performance on the artificial data, indicating no overfitting. Significance: In healthcare, it is common to only have a small collection of high-quality data and labels, or a larger database with much lower quality (and less relevant) labels. The paradigm presented here, involving model-based performance boosting, provides a solution through transfer learning on a large realistic artificial database, and a partially relevant real database.

Large Language Models (LLMs) have become indispensable in real-world applications. However, their widespread adoption raises significant safety concerns, particularly in responding to socially harmful questions. Despite substantial efforts to improve model safety through alignment, aligned models can still have their safety protections undermined by subsequent fine-tuning - even when the additional training data appears benign. In this paper, we empirically demonstrate that this vulnerability stems from the sensitivity of safety-critical low-rank subspaces in LLM parameters to fine-tuning. Building on this insight, we propose a novel training-free method, termed Low-Rank Extrapolation (LoX), to enhance safety robustness by extrapolating the safety subspace of an aligned LLM. Our experimental results confirm the effectiveness of LoX, demonstrating significant improvements in robustness against both benign and malicious fine-tuning attacks while preserving the model's adaptability to new tasks. For instance, LoX leads to 11% to 54% absolute reductions in attack success rates (ASR) facing benign or malicious fine-tuning attacks. By investigating the ASR landscape of parameters, we attribute the success of LoX to that the extrapolation moves LLM parameters to a flatter zone, thereby less sensitive to perturbations. The code is available at github.com/VITA-Group/LoX.

Vision-language models in pathology enable multimodal case retrieval and automated report generation. Many of the models developed so far, however, have been trained on pathology reports that include information which cannot be inferred from paired whole slide images (e.g., patient history), potentially leading to hallucinated sentences in generated reports. To this end, we investigate how the selection of information from pathology reports for vision-language modeling affects the quality of the multimodal representations and generated reports. More concretely, we compare a model trained on full reports against a model trained on preprocessed reports that only include sentences describing the cell and tissue appearances based on the H&E-stained slides. For the experiments, we built upon the BLIP-2 framework and used a cutaneous melanocytic lesion dataset of 42,433 H&E-stained whole slide images and 19,636 corresponding pathology reports. Model performance was assessed using image-to-text and text-to-image retrieval, as well as qualitative evaluation of the generated reports by an expert pathologist. Our results demonstrate that text preprocessing prevents hallucination in report generation. Despite the improvement in the quality of the generated reports, training the vision-language model on full reports showed better cross-modal retrieval performance.

Millions of melanocytic skin lesions are examined by pathologists each year, the majority of which concern common nevi (i.e., ordinary moles). While most of these lesions can be diagnosed in seconds, writing the corresponding pathology report is much more time-consuming. Automating part of the report writing could, therefore, alleviate the increasing workload of pathologists. In this work, we develop a vision-language model specifically for the pathology domain of cutaneous melanocytic lesions. The model follows the Contrastive Captioner framework and was trained and evaluated using a melanocytic lesion dataset of 42,512 H&E-stained whole slide images and 19,645 corresponding pathology reports. Our results show that the quality scores of model-generated reports were on par with pathologist-written reports for common nevi, assessed by an expert pathologist in a reader study. While report generation revealed to be more difficult for rare melanocytic lesion subtypes, the cross-modal retrieval performance for these cases was considerably better.

We investigate Josephson arrays consisting of a dice-lattice network of superconducting weak links surrounding rhombic plaquettes of proximitized semiconductor. Josephson coupling of the weak links and electron density in the plaquettes are independently controlled by separate electrostatic gates. Applied magnetic flux results in an intricate pattern of switching currents associated with frustration, f. For depleted plaquettes, the switching current is nearly periodic in f, expected for a phase-only description, while occupied plaquettes yield a decreasing envelope of switching currents with increasing f. A model of flux dependence based on ballistic small-area junctions and diffusive large-area plaquettes yields excellent agreement with experiment.

Accurately classifying chemical structures is essential for cheminformatics and bioinformatics, including tasks such as identifying bioactive compounds of interest, screening molecules for toxicity to humans, finding non-organic compounds with desirable material properties, or organizing large chemical libraries for drug discovery or environmental monitoring. However, manual classification is labor-intensive and difficult to scale to large chemical databases. Existing automated approaches either rely on manually constructed classification rules, or the use of deep learning methods that lack explainability. This work presents an approach that uses generative artificial intelligence to automatically write chemical classifier programs for classes in the Chemical Entities of Biological Interest (ChEBI) database. These programs can be used for efficient deterministic run-time classification of SMILES structures, with natural language explanations. The programs themselves constitute an explainable computable ontological model of chemical class nomenclature, which we call the ChEBI Chemical Class Program Ontology (C3PO). We validated our approach against the ChEBI database, and compared our results against state of the art deep learning models. We also demonstrate the use of C3PO to classify out-of-distribution examples taken from metabolomics repositories and natural product databases. We also demonstrate the potential use of our approach to find systematic classification errors in existing chemical databases, and show how an ensemble artificial intelligence approach combining generated ontologies, automated literature search, and multimodal vision models can be used to pinpoint potential errors requiring expert validation

We develop an econometric framework integrating heavy-tailed Student's t distributions with behavioral probability weighting while preserving infinite divisibility. Using 432{,}752 observations across 86 assets (2004--2024), we demonstrate Student's t specifications outperform Gaussian models in 88.4\% of cases. Bounded probability-weighting transformations preserve mathematical properties required for dynamic pricing. Gaussian models underestimate 99\% Value-at-Risk by 19.7\% versus 3.2\% for our specification. Joint estimation procedures identify tail and behavioral parameters with established asymptotic properties. Results provide robust inference for asset-pricing applications where heavy tails and behavioral distortions coexist.

Intelligent agents designed for interactive environments face significant challenges in text-based games, a domain that demands complex reasoning and adaptability. While agents based on large language models (LLMs) using self-reflection have shown promise, they struggle when initially successful and exhibit reduced effectiveness when using smaller LLMs. We introduce Sweet&Sour, a novel approach that addresses these limitations in existing reflection methods by incorporating positive experiences and managed memory to enrich the context available to the agent at decision time. Our comprehensive analysis spans both closed- and open-source LLMs and demonstrates the effectiveness of Sweet&Sour in improving agent performance, particularly in scenarios where previous approaches fall short.

We present photometric properties and distance measurements of 252 high redshift Type Ia supernovae (0.15 < z < 1.1) discovered during the first three years of the Supernova Legacy Survey (SNLS). These events were detected and their multi-colour light curves measured using the MegaPrime/MegaCam instrument at the Canada-France-Hawaii Telescope (CFHT), by repeatedly imaging four one-square degree fields in four bands. Follow-up spectroscopy was performed at the VLT, Gemini and Keck telescopes to confirm the nature of the supernovae and to measure their redshifts. Systematic uncertainties arising from light curve modeling are studied, making use of two techniques to derive the peak magnitude, shape and colour of the supernovae, and taking advantage of a precise calibration of the SNLS fields. A flat LambdaCDM cosmological fit to 231 SNLS high redshift Type Ia supernovae alone gives Omega_M = 0.211 +/- 0.034(stat) +/- 0.069(sys). The dominant systematic uncertainty comes from uncertainties in the photometric calibration. Systematic uncertainties from light curve fitters come next with a total contribution of +/- 0.026 on Omega_M. No clear evidence is found for a possible evolution of the slope (beta) of the colour-luminosity relation with redshift.

Dark matter makes up approximately 85% of total matter in our universe, yet it has never been directly observed in any laboratory on Earth. The origin of dark matter is one of the most important questions in contemporary physics, and a convincing detection of dark matter would be a Nobel-Prize-level breakthrough in fundamental science. The ABRACADABRA experiment was specifically designed to search for dark matter. Although it has not yet made a discovery, ABRACADABRA has produced several dark matter search results widely endorsed by the physics community. The experiment generates ultra-long time-series data at a rate of 10 million samples per second, where the dark matter signal would manifest itself as a sinusoidal oscillation mode within the ultra-long time series. In this paper, we present the TIDMAD -- a comprehensive data release from the ABRACADABRA experiment including three key components: an ultra-long time series dataset divided into training, validation, and science subsets; a carefully-designed denoising score for direct model benchmarking; and a complete analysis framework which produces a community-standard dark matter search result suitable for publication as a physics paper. This data release enables core AI algorithms to extract the signal and produce real physics results thereby advancing fundamental science. The data downloading and associated analysis scripts are available at https://github.com/jessicafry/TIDMAD

Semantic segmentation is crucial for various biomedical applications, yet its reliance on large annotated datasets presents a bottleneck due to the high cost and specialized expertise required for manual labeling. Active Learning (AL) aims to mitigate this challenge by querying only the most informative samples, thereby reducing annotation effort. However, in the domain of 3D biomedical imaging, there is no consensus on whether AL consistently outperforms Random sampling. Four evaluation pitfalls hinder the current methodological assessment. These are (1) restriction to too few datasets and annotation budgets, (2) using 2D models on 3D images without partial annotations, (3) Random baseline not being adapted to the task, and (4) measuring annotation cost only in voxels. In this work, we introduce nnActive, an open-source AL framework that overcomes these pitfalls by (1) means of a large scale study spanning four biomedical imaging datasets and three label regimes, (2) extending nnU-Net by using partial annotations for training with 3D patch-based query selection, (3) proposing Foreground Aware Random sampling strategies tackling the foreground-background class imbalance of medical images and (4) propose the foreground efficiency metric, which captures the low annotation cost of background-regions. We reveal the following findings: (A) while all AL methods outperform standard Random sampling, none reliably surpasses an improved Foreground Aware Random sampling; (B) benefits of AL depend on task specific parameters; (C) Predictive Entropy is overall the best performing AL method, but likely requires the most annotation effort; (D) AL performance can be improved with more compute intensive design choices. As a holistic, open-source framework, nnActive can serve as a catalyst for research and application of AL in 3D biomedical imaging. Code is at: https://github.com/MIC-DKFZ/nnActive

We present phi-4, a 14-billion parameter language model developed with a training recipe that is centrally focused on data quality. Unlike most language models, where pre-training is based primarily on organic data sources such as web content or code, phi-4 strategically incorporates synthetic data throughout the training process. While previous models in the Phi family largely distill the capabilities of a teacher model (specifically GPT-4), phi-4 substantially surpasses its teacher model on STEM-focused QA capabilities, giving evidence that our data-generation and post-training techniques go beyond distillation. Despite minimal changes to the phi-3 architecture, phi-4 achieves strong performance relative to its size -- especially on reasoning-focused benchmarks -- due to improved data, training curriculum, and innovations in the post-training scheme.

Evaluating anomaly detection algorithms in time series data is critical as inaccuracies can lead to flawed decision-making in various domains where real-time analytics and data-driven strategies are essential. Traditional performance metrics assume iid data and fail to capture the complex temporal dynamics and specific characteristics of time series anomalies, such as early and delayed detections. We introduce Proximity-Aware Time series anomaly Evaluation (PATE), a novel evaluation metric that incorporates the temporal relationship between prediction and anomaly intervals. PATE uses proximity-based weighting considering buffer zones around anomaly intervals, enabling a more detailed and informed assessment of a detection. Using these weights, PATE computes a weighted version of the area under the Precision and Recall curve. Our experiments with synthetic and real-world datasets show the superiority of PATE in providing more sensible and accurate evaluations than other evaluation metrics. We also tested several state-of-the-art anomaly detectors across various benchmark datasets using the PATE evaluation scheme. The results show that a common metric like Point-Adjusted F1 Score fails to characterize the detection performances well, and that PATE is able to provide a more fair model comparison. By introducing PATE, we redefine the understanding of model efficacy that steers future studies toward developing more effective and accurate detection models.

This work presents an unsupervised method for automatically constructing and expanding topic taxonomies by using instruction-based fine-tuned LLMs (Large Language Models). We apply topic modeling and keyword extraction techniques to create initial topic taxonomies and LLMs to post-process the resulting terms and create a hierarchy. To expand an existing taxonomy with new terms, we use zero-shot prompting to find out where to add new nodes, which, to our knowledge, is the first work to present such an approach to taxonomy tasks. We use the resulting taxonomies to assign tags that characterize merchants from a retail bank dataset. To evaluate our work, we asked 12 volunteers to answer a two-part form in which we first assessed the quality of the taxonomies created and then the tags assigned to merchants based on that taxonomy. The evaluation revealed a coherence rate exceeding 90% for the chosen taxonomies, while the average coherence for merchant tagging surpassed 80%.

We used machine learning and artificial intelligence: 1) to measure levels of peace in countries from news and social media and 2) to develop on-line tools that promote peace by helping users better understand their own media diet. For news media, we used neural networks to measure levels of peace from text embeddings of on-line news sources. The model, trained on one news media dataset also showed high accuracy when used to analyze a different news dataset. For social media, such as YouTube, we developed other models to measure levels of social dimensions important in peace using word level (GoEmotions) and context level (Large Language Model) methods. To promote peace, we note that 71% of people 20-40 years old daily view most of their news through short videos on social media. Content creators of these videos are biased towards creating videos with emotional activation, making you angry to engage you, to increase clicks. We developed and tested a Chrome extension, MirrorMirror, which provides real-time feedback to YouTube viewers about the peacefulness of the media they are watching. Our long term goal is for MirrorMirror to evolve into an open-source tool for content creators, journalists, researchers, platforms, and individual users to better understand the tone of their media creation and consumption and its effects on viewers. Moving beyond simple engagement metrics, we hope to encourage more respectful, nuanced, and informative communication.

We propose a machine learning-based extension of the classical binomial option pricing model that incorporates key market microstructure effects. Traditional models assume frictionless markets, overlooking empirical features such as bid-ask spreads, discrete price movements, and serial return correlations. Our framework augments the binomial tree with path-dependent transition probabilities estimated via Random Forest classifiers trained on high-frequency market data. This approach preserves no-arbitrage conditions while embedding real-world trading dynamics into the pricing model. Using 46,655 minute-level observations of SPY from January to June 2025, we achieve an AUC of 88.25% in forecasting one-step price movements. Order flow imbalance is identified as the most influential predictor, contributing 43.2% to feature importance. After resolving time-scaling inconsistencies in tree construction, our model yields option prices that deviate by 13.79% from Black-Scholes benchmarks, highlighting the impact of microstructure on fair value estimation. While computational limitations restrict the model to short-term derivatives, our results offer a robust, data-driven alternative to classical pricing methods grounded in empirical market behavior.

We study a discrete model for generalized exchange-driven growth in which the particle exchanged between two clusters is not limited to be of size one. This set of models include as special cases the usual exchange-driven growth system and the coagulation-fragmentation system with binary fragmentation. Under reasonable general condition on the rate coefficients we establish the existence of admissible solutions, meaning solutions that are obtained as appropriate limit of solutions to a finite-dimensional truncation of the infinite-dimensional ODE. For these solutions we prove that, in the class of models we call isolated both the total number of particles and the total mass are conserved, whereas in those models we can non-isolated only the mass is conserved. Additionally, under more restrictive growth conditions for the rate equations we obtain uniqueness of solutions to the initial value problems.

Selective Classification, wherein models can reject low-confidence predictions, promises reliable translation of machine-learning based classification systems to real-world scenarios such as clinical diagnostics. While current evaluation of these systems typically assumes fixed working points based on pre-defined rejection thresholds, methodological progress requires benchmarking the general performance of systems akin to the AUROC in standard classification. In this work, we define 5 requirements for multi-threshold metrics in selective classification regarding task alignment, interpretability, and flexibility, and show how current approaches fail to meet them. We propose the Area under the Generalized Risk Coverage curve (AUGRC), which meets all requirements and can be directly interpreted as the average risk of undetected failures. We empirically demonstrate the relevance of AUGRC on a comprehensive benchmark spanning 6 data sets and 13 confidence scoring functions. We find that the proposed metric substantially changes metric rankings on 5 out of the 6 data sets.

We present observations and timing analyses of 68 millisecond pulsars (MSPs) comprising the 15-year data set of the North American Nanohertz Observatory for Gravitational Waves (NANOGrav). NANOGrav is a pulsar timing array (PTA) experiment that is sensitive to low-frequency gravitational waves. This is NANOGrav's fifth public data release, including both "narrowband" and "wideband" time-of-arrival (TOA) measurements and corresponding pulsar timing models. We have added 21 MSPs and extended our timing baselines by three years, now spanning nearly 16 years for some of our sources. The data were collected using the Arecibo Observatory, the Green Bank Telescope, and the Very Large Array between frequencies of 327 MHz and 3 GHz, with most sources observed approximately monthly. A number of notable methodological and procedural changes were made compared to our previous data sets. These improve the overall quality of the TOA data set and are part of the transition to new pulsar timing and PTA analysis software packages. For the first time, our data products are accompanied by a full suite of software to reproduce data reduction, analysis, and results. Our timing models include a variety of newly detected astrometric and binary pulsar parameters, including several significant improvements to pulsar mass constraints. We find that the time series of 23 pulsars contain detectable levels of red noise, 10 of which are new measurements. In this data set, we find evidence for a stochastic gravitational-wave background.

Light emission from galaxies exhibit diverse brightness profiles, influenced by factors such as galaxy type, structural features and interactions with other galaxies. Elliptical galaxies feature more uniform light distributions, while spiral and irregular galaxies have complex, varied light profiles due to their structural heterogeneity and star-forming activity. In addition, galaxies with an active galactic nucleus (AGN) feature intense, concentrated emission from gas accretion around supermassive black holes, superimposed on regular galactic light, while quasi-stellar objects (QSO) are the extreme case of the AGN emission dominating the galaxy. The challenge of identifying AGN and QSO has been discussed many times in the literature, often requiring multi-wavelength observations. This paper introduces a novel approach to identify AGN and QSO from a single image. Diffusion models have been recently developed in the machine-learning literature to generate realistic-looking images of everyday objects. Utilising the spatial resolving power of the Euclid VIS images, we created a diffusion model trained on one million sources, without using any source pre-selection or labels. The model learns to reconstruct light distributions of normal galaxies, since the population is dominated by them. We condition the prediction of the central light distribution by masking the central few pixels of each source and reconstruct the light according to the diffusion model. We further use this prediction to identify sources that deviate from this profile by examining the reconstruction error of the few central pixels regenerated in each source's core. Our approach, solely using VIS imaging, features high completeness compared to traditional methods of AGN and QSO selection, including optical, near-infrared, mid-infrared, and X-rays.

This study developed a novel method for detecting hypernuclear events recorded in nuclear emulsion sheets using machine learning techniques. The artificial neural network-based object detection model was trained on surrogate images created through Monte Carlo simulations and image-style transformations using generative adversarial networks. The performance of the proposed model was evaluated using alpha-decay events obtained from the J-PARC E07 emulsion data. The model achieved approximately twice the detection efficiency of conventional image processing and reduced the time spent on manual visual inspection by approximately 1/17. The established method was successfully applied to the detection of hypernuclear events. This approach is a state-of-the-art tool for discovering rare events recorded in nuclear emulsion sheets without any real data for training.

Context. Cosmic voids are vast underdense regions in the cosmic web that encode crucial information about structure formation, the composition of the Universe, and its expansion history. Due to their lower density, these regions are less affected by non-linear gravitational dynamics, making them suitable candidates for analysis using semi-analytic methods. Aims. We assess the accuracy of the PINOCCHIO code, a fast tool for generating dark matter halo catalogs based on Lagrangian Perturbation Theory, in modeling the statistical properties of cosmic voids. We validate this approach by comparing the resulting void statistics measured from PINOCCHIO to those obtained from N-body simulations. Methods. We generate a set of simulations using PINOCCHIO and OpenGADGET3, assuming a fiducial cosmology and varying the resolution. For a given resolution, the simulations share the same initial conditions between the different simulation codes. Snapshots are saved at multiple redshifts for each simulation and post-processed using the watershed void finder VIDE to identify cosmic voids. For each simulation code, we measure the following statistics: void size function, void ellipticity function, core density function, and the void radial density profile. We use these statistics to quantify the accuracy of PINOCCHIO relative to OpenGADGET3 in the context of cosmic voids. Results. We find agreement for all void statistics at better than 2{\sigma} between PINOCCHIO and OpenGADGET3, with no systematic difference in redshift trends. This demonstrates that the PINOCCHIO code can reliably produce void statistics with high computational efficiency compared to full N-body simulations.

Creating knowledge bases and ontologies is a time consuming task that relies on a manual curation. AI/NLP approaches can assist expert curators in populating these knowledge bases, but current approaches rely on extensive training data, and are not able to populate arbitrary complex nested knowledge schemas. Here we present Structured Prompt Interrogation and Recursive Extraction of Semantics (SPIRES), a Knowledge Extraction approach that relies on the ability of Large Language Models (LLMs) to perform zero-shot learning (ZSL) and general-purpose query answering from flexible prompts and return information conforming to a specified schema. Given a detailed, user-defined knowledge schema and an input text, SPIRES recursively performs prompt interrogation against GPT-3+ to obtain a set of responses matching the provided schema. SPIRES uses existing ontologies and vocabularies to provide identifiers for all matched elements. We present examples of use of SPIRES in different domains, including extraction of food recipes, multi-species cellular signaling pathways, disease treatments, multi-step drug mechanisms, and chemical to disease causation graphs. Current SPIRES accuracy is comparable to the mid-range of existing Relation Extraction (RE) methods, but has the advantage of easy customization, flexibility, and, crucially, the ability to perform new tasks in the absence of any training data. This method supports a general strategy of leveraging the language interpreting capabilities of LLMs to assemble knowledge bases, assisting manual knowledge curation and acquisition while supporting validation with publicly-available databases and ontologies external to the LLM. SPIRES is available as part of the open source OntoGPT package: https://github.com/ monarch-initiative/ontogpt.

Data-driven scientific discovery requires iterative cycles of literature search, hypothesis generation, and data analysis. Substantial progress has been made towards AI agents that can automate scientific research, but all such agents remain limited in the number of actions they can take before losing coherence, thus limiting the depth of their findings. Here we present Kosmos, an AI scientist that automates data-driven discovery. Given an open-ended objective and a dataset, Kosmos runs for up to 12 hours performing cycles of parallel data analysis, literature search, and hypothesis generation before synthesizing discoveries into scientific reports. Unlike prior systems, Kosmos uses a structured world model to share information between a data analysis agent and a literature search agent. The world model enables Kosmos to coherently pursue the specified objective over 200 agent rollouts, collectively executing an average of 42,000 lines of code and reading 1,500 papers per run. Kosmos cites all statements in its reports with code or primary literature, ensuring its reasoning is traceable. Independent scientists found 79.4% of statements in Kosmos reports to be accurate, and collaborators reported that a single 20-cycle Kosmos run performed the equivalent of 6 months of their own research time on average. Furthermore, collaborators reported that the number of valuable scientific findings generated scales linearly with Kosmos cycles (tested up to 20 cycles). We highlight seven discoveries made by Kosmos that span metabolomics, materials science, neuroscience, and statistical genetics. Three discoveries independently reproduce findings from preprinted or unpublished manuscripts that were not accessed by Kosmos at runtime, while four make novel contributions to the scientific literature.

Ongoing and upcoming galaxy redshift surveys, such as the Dark Energy Spectroscopic Instrument (DESI) survey, will observe vast regions of sky and a wide range of redshifts. In order to model the observations and address various systematic uncertainties, N-body simulations are routinely adopted, however, the number of large simulations with sufficiently high mass resolution is usually limited by available computing time. Therefore, achieving a simulation volume with the effective statistical errors significantly smaller than those of the observations becomes prohibitively expensive. In this study, we apply the Convergence Acceleration by Regression and Pooling (CARPool) method to mitigate the sample variance of the DESI-like galaxy clustering in the AbacusSummit simulations, with the assistance of the quasi-N-body simulations FastPM. Based on the halo occupation distribution (HOD) models, we construct different FastPM galaxy catalogs, including the luminous red galaxies (LRGs), emission line galaxies (ELGs), and quasars, with their number densities and two-point clustering statistics well matched to those of AbacusSummit. We also employ the same initial conditions between AbacusSummit and FastPM to achieve high cross-correlation, as it is useful in effectively suppressing the variance. Our method of reducing noise in clustering is equivalent to performing a simulation with volume larger by a factor of 5 and 4 for LRGs and ELGs, respectively. We also mitigate the standard deviation of the LRG bispectrum with the triangular configurations k_2=2k_1=0.2 h/Mpc by a factor of 1.6. With smaller sample variance on galaxy clustering, we are able to constrain the baryon acoustic oscillations (BAO) scale parameters to higher precision. The CARPool method will be beneficial to better constrain the theoretical systematics of BAO, redshift space distortions (RSD) and primordial non-Gaussianity (NG).

It is essential to have a method to map an unknown terrain for various applications. For places where human access is not possible, a method should be proposed to identify the environment. Exploration, disaster relief, transportation and many other purposes would be convenient if a map of the environment is available. Replicating the human vision system using stereo cameras would be an optimum solution. In this work, we have used laser ranging based technique fused with stereo cameras to extract dimension of objects for mapping. The distortions were calibrated using mathematical model of the camera. By means of Semi Global Block Matching [1] disparity map was generated and reduces the noise using novel noise reduction method of disparity map by dilation. The Data from the Laser Range Finder (LRF) and noise reduced vision data has been used to identify the object parameters.

The star formation and metal enrichment histories of galaxies - at any epoch - constitute one of the key properties of galaxies, and their measurement is a core aim of observational extragalactic astronomy. The lack of deep rest-frame optical coverage at high-redshift has made robust constraints elusive, but this is now changing thanks to the James Webb Space Telescope (JWST). In preparation for the constraints provided by JWST we explore the star formation and metal enrichment histories of galaxies at z=5-13 using the First Light And Reionisation Epoch Simulations (FLARES) suite. Built on the EAGLE model, the unique strategy of FLARES allows us to simulate a wide range of stellar masses (and luminosities) and environments. While we predict significant redshift evolution of average ages and specific star formation rates our core result is a mostly flat relationship of age and specific star formation rate with stellar mass. We also find that galaxies in this epoch predominantly have strongly rising star formation histories, albeit with the magnitude dropping with redshift and stellar mass. In terms of chemical enrichment we predict a strong stellar mass - metallicity relation present at z=10 and beyond alongside significant alpha-enhancement. Finally, we find no environmental dependence of the relationship between age, specific star formation rate, or metallicity with stellar mass.

Galaxy clusters selected based on overdensities of galaxies in photometric surveys provide the largest cluster samples. Yet modeling the selection function of such samples is complicated by non-cluster members projected along the line of sight (projection effects) and the potential detection of unvirialized objects (contamination). We empirically constrain the magnitude of these effects by cross-matching galaxy clusters selected in the Dark Energy survey data with the \rdmpr, algorithm with significant detections in three South Pole Telescope surveys (SZ, pol-ECS, pol-500d). For matched clusters, we augment the \rdmpr,catalog by the SPT detection significance. For unmatched objects we use the SPT detection threshold as an upper limit on the SZe signature. Using a Bayesian population model applied to the collected multi-wavelength data, we explore various physically motivated models to describe the relationship between observed richness and halo mass. Our analysis reveals the limitations of a simple lognormal scatter model in describing the data. We rule out significant contamination by unvirialized objects at the high-richness end of the sample. While dedicated simulations offer a well-fitting calibration of projection effects, our findings suggest the presence of redshift-dependent trends that these simulations may not have captured. Our findings highlight that modeling the selection function of optically detected clusters remains a complicated challenge, requiring a combination of simulation and data-driven approaches.

This paper describes the 2018 Planck CMB likelihoods, following a hybrid approach similar to the 2015 one, with different approximations at low and high multipoles, and implementing several methodological and analysis refinements. With more realistic simulations, and better correction and modelling of systematics, we can now make full use of the High Frequency Instrument polarization data. The low-multipole 100x143 GHz EE cross-spectrum constrains the reionization optical-depth parameter tau to better than 15% (in combination with with the other low- and high-ell likelihoods). We also update the 2015 baseline low-ell joint TEB likelihood based on the Low Frequency Instrument data, which provides a weaker tau constraint. At high multipoles, a better model of the temperature-to-polarization leakage and corrections for the effective calibrations of the polarization channels (polarization efficiency or PE) allow us to fully use the polarization spectra, improving the constraints on the LambdaCDM parameters by 20 to 30% compared to TT-only constraints. Tests on the modelling of the polarization demonstrate good consistency, with some residual modelling uncertainties, the accuracy of the PE modelling being the main limitation. Using our various tests, simulations, and comparison between different high-ell implementations, we estimate the consistency of the results to be better than the 0.5sigma level. Minor curiosities already present before (differences between ell<800 and ell>800 parameters or the preference for more smoothing of the C_ell peaks) are shown to be driven by the TT power spectrum and are not significantly modified by the inclusion of polarization. Overall, the legacy Planck CMB likelihoods provide a robust tool for constraining the cosmological model and represent a reference for future CMB observations. (Abridged)

Through gravitational lensing, galaxy clusters can magnify supernovae (SNe) and create multiple images of the same SN. This enables measurements of cosmological parameters, which will be increasingly important in light of upcoming telescopic surveys. We study the prospects of detecting strongly lensed SNe in cluster fields with the Nancy Grace Roman Space Telescope (Roman)'s High Latitude Time Domain Survey (HLTDS) and the Vera C. Rubin Observatory's Legacy Survey of Space and Time (LSST). We employed two approaches: one focusing on known multiply imaged galaxies behind clusters, along with the SN rates specific to those galaxies, and another based on the expected number of lensed SNe exploding in a given volume behind a galaxy cluster. We collected all the clusters in the literature that feature a well-constrained lens model and multiply imaged galaxies behind clusters with high-quality data for the lensed galaxies. This allowed us to determine the SN rate for each galaxy. We provide predictions for 46 clusters visible to the Vera C. Rubin Observatory, as well as for 9 observable by Roman's HLTDS, depending on whether the clusters fall within the survey's observing field. We predict that the number of multiply imaged SNe discovered by LSST in its first three years is 3.95 pm 0.89 from the first approach or 4.94 pm 1.02 from the second. For the HLTDS, the expected number of multiply imaged SNe ranges from 0.38 pm 0.15 to 5.2 pm 2.2, depending on the specific cluster observed, however, the fields to be targeted remain a matter of discussion. We conclude that LSST offers great prospects for detecting multiply imaged SNe. Our predictions are effectively lower limits, as we only considered the most massive and well-studied clusters. We provide a recommendation for HLTDS observing field selection, namely: either MACS J0553.4-3342 or Abell 1758a should be observed by the survey.

We present LFM2, a family of Liquid Foundation Models designed for efficient on-device deployment and strong task capabilities. Using hardware-in-the-loop architecture search under edge latency and memory constraints, we obtain a compact hybrid backbone that combines gated short convolutions with a small number of grouped query attention blocks, delivering up to 2x faster prefill and decode on CPUs compared to similarly sized models. The LFM2 family covers 350M-8.3B parameters, including dense models (350M, 700M, 1.2B, 2.6B) and a mixture-of-experts variant (8.3B total, 1.5B active), all with 32K context length. LFM2's training pipeline includes a tempered, decoupled Top-K knowledge distillation objective that avoids support mismatch; curriculum learning with difficulty-ordered data; and a three-stage post-training recipe of supervised fine-tuning, length-normalized preference optimization, and model merging. Pre-trained on 10-12T tokens, LFM2 models achieve strong results across diverse benchmarks; for example, LFM2-2.6B reaches 79.56% on IFEval and 82.41% on GSM8K. We further build multimodal and retrieval variants: LFM2-VL for vision-language tasks, LFM2-Audio for speech, and LFM2-ColBERT for retrieval. LFM2-VL supports tunable accuracy-latency tradeoffs via token-efficient visual processing, while LFM2-Audio separates audio input and output pathways to enable real-time speech-to-speech interaction competitive with models 3x larger. LFM2-ColBERT provides a low-latency encoder for queries and documents, enabling high-performance retrieval across multiple languages. All models are released with open weights and deployment packages for ExecuTorch, llama.cpp, and vLLM, making LFM2 a practical base for edge applications that need fast, memory-efficient inference and strong task capabilities.

Enterprises grapple with the significant challenge of managing proprietary unstructured data, hindering efficient information retrieval. This has led to the emergence of AI-driven information retrieval solutions, designed to adeptly extract relevant insights to address employee inquiries. These solutions often leverage pre-trained embedding models and generative models as foundational components. While pre-trained embeddings may exhibit proximity or disparity based on their original training objectives, they might not fully align with the unique characteristics of enterprise-specific data, leading to suboptimal alignment with the retrieval goals of enterprise environments. In this paper, we propose a methodology to fine-tune pre-trained embedding models specifically for enterprise environments. By adapting the embeddings to better suit the retrieval tasks prevalent in enterprises, we aim to enhance the performance of information retrieval solutions. We discuss the process of fine-tuning, its effect on retrieval accuracy, and the potential benefits for enterprise information management. Our findings demonstrate the efficacy of fine-tuned embedding models in improving the precision and relevance of search results in enterprise settings.

Self-supervised learning (SSL) has achieved major advances in natural images and video understanding, but challenges remain in domains like echocardiography (heart ultrasound) due to subtle anatomical structures, complex temporal dynamics, and the current lack of domain-specific pre-trained models. Existing SSL approaches such as contrastive, masked modeling, and clustering-based methods struggle with high intersample similarity, sensitivity to low PSNR inputs common in ultrasound, or aggressive augmentations that distort clinically relevant features. We present DISCOVR (Distilled Image Supervision for Cross Modal Video Representation), a self-supervised dual branch framework for cardiac ultrasound video representation learning. DISCOVR combines a clustering-based video encoder that models temporal dynamics with an online image encoder that extracts fine-grained spatial semantics. These branches are connected through a semantic cluster distillation loss that transfers anatomical knowledge from the evolving image encoder to the video encoder, enabling temporally coherent representations enriched with fine-grained semantic understanding. Evaluated on six echocardiography datasets spanning fetal, pediatric, and adult populations, DISCOVR outperforms both specialized video anomaly detection methods and state-of-the-art video-SSL baselines in zero-shot and linear probing setups, and achieves superior segmentation transfer.

Understanding the galaxy-halo relationship is not only key for elucidating the interplay between baryonic and dark matter, it is essential for creating large mock galaxy catalogues from N-body simulations. High-resolution hydrodynamical simulations are limited to small volumes by their large computational demands, hindering their use for comparisons with wide-field observational surveys. We overcome this limitation by using the First Light and Reionisation Epoch Simulations (FLARES), a suite of high-resolution (M_gas = 1.8 x 10^6 M_Sun) zoom simulations drawn from a large, (3.2 cGpc)^3 box. We use an extremely randomised trees machine learning approach to model the relationship between galaxies and their subhaloes in a wide range of environments. This allows us to build mock catalogues with dynamic ranges that surpass those obtainable through periodic simulations. The low cost of the zoom simulations facilitates multiple runs of the same regions, differing only in the random number seed of the subgrid models; changing this seed introduces a butterfly effect, leading to random differences in the properties of matching galaxies. This randomness cannot be learnt by a deterministic machine learning model, but by sampling the noise and adding it post-facto to our predictions, we are able to recover the distributions of the galaxy properties we predict (stellar mass, star formation rate, metallicity, and size) remarkably well. We also explore the resolution-dependence of our models' performances and find minimal depreciation down to particle resolutions of order M_DM ~ 10^8 M_Sun, enabling the future application of our models to large dark matter-only boxes.

With its exquisite sensitivity, wavelength coverage, and spatial and spectral resolution, the James Webb Space Telescope is poised to revolutionise our view of the distant, high-redshift (z>5) Universe. While Webb's spectroscopic observations will be transformative for the field, photometric observations play a key role in identifying distant objects and providing more comprehensive samples than accessible to spectroscopy alone. In addition to identifying objects, photometric observations can also be used to infer physical properties and thus be used to constrain galaxy formation models. However, inferred physical properties from broadband photometric observations, particularly in the absence of spectroscopic redshifts, often have large uncertainties. With the development of new tools for forward modelling simulations it is now routinely possible to predict observational quantities, enabling a direct comparison with observations. With this in mind, in this work, we make predictions for the colour evolution of galaxies at z=5-15 using the FLARES: First Light And Reionisation Epoch Simulations cosmological hydrodynamical simulation suite. We predict a complex evolution, driven predominantly by strong nebular line emission passing through individual bands. These predictions are in good agreement with existing constraints from Hubble and Spitzer as well as some of the first results from Webb. We also contrast our predictions with other models in the literature: while the general trends are similar we find key differences, particularly in the strength of features associated with strong nebular line emission. This suggests photometric observations alone should provide useful discriminating power between different models.

We present griz light curves of 251 Type Ia Supernovae (SNe Ia) from the first 3 years of the Dark Energy Survey Supernova Program's (DES-SN) spectroscopically classified sample. The photometric pipeline described in this paper produces the calibrated fluxes and associated uncertainties used in the cosmological parameter analysis (Brout et al. 2018-SYS, DES Collaboration et al. 2018) by employing a scene modeling approach that simultaneously forward models a variable transient flux and temporally constant host galaxy. We inject artificial point sources onto DECam images to test the accuracy of our photometric method. Upon comparison of input and measured artificial supernova fluxes, we find flux biases peak at 3 mmag. We require corrections to our photometric uncertainties as a function of host galaxy surface brightness at the transient location, similar to that seen by the DES Difference Imaging Pipeline used to discover transients. The public release of the light curves can be found at https://des.ncsa.illinois.edu/releases/sn.

We present DeepSeek-V3, a strong Mixture-of-Experts (MoE) language model with 671B total parameters with 37B activated for each token. To achieve efficient inference and cost-effective training, DeepSeek-V3 adopts Multi-head Latent Attention (MLA) and DeepSeekMoE architectures, which were thoroughly validated in DeepSeek-V2. Furthermore, DeepSeek-V3 pioneers an auxiliary-loss-free strategy for load balancing and sets a multi-token prediction training objective for stronger performance. We pre-train DeepSeek-V3 on 14.8 trillion diverse and high-quality tokens, followed by Supervised Fine-Tuning and Reinforcement Learning stages to fully harness its capabilities. Comprehensive evaluations reveal that DeepSeek-V3 outperforms other open-source models and achieves performance comparable to leading closed-source models. Despite its excellent performance, DeepSeek-V3 requires only 2.788M H800 GPU hours for its full training. In addition, its training process is remarkably stable. Throughout the entire training process, we did not experience any irrecoverable loss spikes or perform any rollbacks. The model checkpoints are available at https://github.com/deepseek-ai/DeepSeek-V3.

We analyse the robustness of the DESI 2024 cosmological inference from fits to the full shape of the galaxy power spectrum to uncertainties in the Halo Occupation Distribution (HOD) model of the galaxy-halo connection and the choice of priors on nuisance parameters. We assess variations in the recovered cosmological parameters across a range of mocks populated with different HOD models and find that shifts are often greater than 20% of the expected statistical uncertainties from the DESI data. We encapsulate the effect of such shifts in terms of a systematic covariance term, C_{rm HOD}, and an additional diagonal contribution quantifying the impact of our choice of nuisance parameter priors on the ability of the effective field theory (EFT) model to correctly recover the cosmological parameters of the simulations. These two covariance contributions are designed to be added to the usual covariance term, C_{rm stat}, describing the statistical uncertainty in the power spectrum measurement, in order to fairly represent these sources of systematic uncertainty. This approach is more general and robust to choices of model free parameters or additional external datasets used in cosmological fits than the alternative approach of adding systematic uncertainties at the level of the recovered marginalised parameter posteriors. We compare the approaches within the context of a fixed LambdaCDM model and demonstrate that our method gives conservative estimates of the systematic uncertainty that nevertheless have little impact on the final posteriors obtained from DESI data.

We present the measurements and cosmological implications of the galaxy two-point clustering using over 4.7 million unique galaxy and quasar redshifts in the range 0.1<z<2.1 divided into six redshift bins over a sim 7,500 square degree footprint, from the first year of observations with the Dark Energy Spectroscopic Instrument (DESI Data Release 1). By fitting the full power spectrum, we extend previous DESI DR1 baryon acoustic oscillation (BAO) measurements to include redshift-space distortions and signals from the matter-radiation equality scale. For the first time, this Full-Shape analysis is blinded at the catalogue-level to avoid confirmation bias and the systematic errors are accounted for at the two-point clustering level, which automatically propagates them into any cosmological parameter. When analysing the data in terms of compressed model-agnostic variables, we obtain a combined precision of 4.7\% on the amplitude of the redshift space distortion signal reaching similar precision with just one year of DESI data than with 20 years of observation from previous generation surveys. We analyse the data to directly constrain the cosmological parameters within the LambdaCDM model using perturbation theory and combine this information with the reconstructed DESI DR1 galaxy BAO. Using a Big Bang Nucleosynthesis Gaussian prior on the baryon density parameter, and a Gaussian prior on the spectral index, we constrain the matter density is Omega_m=0.296pm 0.010 and the Hubble constant H_0=(68.63 pm 0.79)[{rm km, s^{-1}Mpc^{-1}}]. Additionally, we measure the amplitude of clustering sigma_8=0.841 pm 0.034. The DESI DR1 results are in agreement with the LambdaCDM model based on general relativity with parameters consistent with those from Planck. The cosmological interpretation of these results in combination with external datasets are presented in a companion paper.

The James Webb Space Telescope (JWST) is set to transform many areas of astronomy, one of the most exciting is the expansion of the redshift frontier to z>10. In its first year alone JWST should discover hundreds of galaxies, dwarfing the handful currently known. To prepare for these powerful observational constraints, we use the First Light And Reionisation Epoch (FLARES) simulations to predict the physical and observational properties of the z>10 population of galaxies accessible to JWST. This is the first time such predictions have been made using a hydrodynamical model validated at low redshift. Our predictions at z=10 are broadly in agreement with current observational constraints on the far-UV luminosity function and UV continuum slope beta, though the observational uncertainties are large. We note tension with recent constraints zsim 13 from Harikane et al. 2022 - compared to these constraints, FLARES predicts objects with the same space density should have an order of magnitude lower luminosity, though this is mitigated slightly if dust attenuation is negligible in these systems. Our predictions suggest that in JWST's first cycle alone, around 600 galaxies should be identified at z>10, with the first small samples available at z>13.

We present cosmological parameter results from the final full-mission Planck measurements of the CMB anisotropies. We find good consistency with the standard spatially-flat 6-parameter LambdaCDM cosmology having a power-law spectrum of adiabatic scalar perturbations (denoted "base LambdaCDM" in this paper), from polarization, temperature, and lensing, separately and in combination. A combined analysis gives dark matter density Omega_c h^2 = 0.120pm 0.001, baryon density Omega_b h^2 = 0.0224pm 0.0001, scalar spectral index n_s = 0.965pm 0.004, and optical depth tau = 0.054pm 0.007 (in this abstract we quote 68,% confidence regions on measured parameters and 95,% on upper limits). The angular acoustic scale is measured to 0.03,% precision, with 100theta_*=1.0411pm 0.0003. These results are only weakly dependent on the cosmological model and remain stable, with somewhat increased errors, in many commonly considered extensions. Assuming the base-LambdaCDM cosmology, the inferred late-Universe parameters are: Hubble constant H_0 = (67.4pm 0.5)km/s/Mpc; matter density parameter Omega_m = 0.315pm 0.007; and matter fluctuation amplitude sigma_8 = 0.811pm 0.006. We find no compelling evidence for extensions to the base-LambdaCDM model. Combining with BAO we constrain the effective extra relativistic degrees of freedom to be N_{rm eff} = 2.99pm 0.17, and the neutrino mass is tightly constrained to sum m_nu< 0.12eV. The CMB spectra continue to prefer higher lensing amplitudes than predicted in base -LambdaCDM at over 2,sigma, which pulls some parameters that affect the lensing amplitude away from the base-LambdaCDM model; however, this is not supported by the lensing reconstruction or (in models that also change the background geometry) BAO data. (Abridged)

African agriculture is undergoing rapid transformation. Annual maps of crop fields are key to understanding the nature of this transformation, but such maps are currently lacking and must be developed using advanced machine learning models trained on high resolution remote sensing imagery. To enable the development of such models, we delineated field boundaries in 33,746 Planet images captured between 2017 and 2023 across the continent using a custom labeling platform with built-in procedures for assessing and mitigating label error. We collected 42,403 labels, including 7,204 labels arising from tasks dedicated to assessing label quality (Class 1 labels), 32,167 from sites mapped once by a single labeller (Class 2) and 3,032 labels from sites where 3 or more labellers were tasked to map the same location (Class 4). Class 1 labels were used to calculate labeller-specific quality scores, while Class 1 and 4 sites mapped by at least 3 labellers were used to further evaluate label uncertainty using a Bayesian risk metric. Quality metrics showed that label quality was moderately high (0.75) for measures of total field extent, but low regarding the number of individual fields delineated (0.33), and the position of field edges (0.05). These values are expected when delineating small-scale fields in 3-5 m resolution imagery, which can be too coarse to reliably distinguish smaller fields, particularly in dense croplands, and therefore requires substantial labeller judgement. Nevertheless, previous work shows that such labels can train effective field mapping models. Furthermore, this large, probabilistic sample on its own provides valuable insight into regional agricultural characteristics, highlighting variations in the median field size and density. The imagery and vectorized labels along with quality information is available for download from two public repositories.

The wavelength-coverage and sensitivity of JWST now enables us to probe the rest-frame UV - optical spectral energy distributions (SEDs) of galaxies at high-redshift (z>4). From these SEDs it is, in principle, through SED fitting possible to infer key physical properties, including stellar masses, star formation rates, and dust attenuation. These in turn can be compared with the predictions of galaxy formation simulations allowing us to validate and refine the incorporated physics. However, the inference of physical properties, particularly from photometry alone, can lead to large uncertainties and potential biases. Instead, it is now possible, and common, for simulations to be forward-modelled to yield synthetic observations that can be compared directly to real observations. In this work, we measure the JWST broadband fluxes and colours of a robust sample of 5<z<10 galaxies using the Cosmic Evolution Early Release Science (CEERS) Survey. We then analyse predictions from a variety of models using the same methodology and compare the NIRCam/F277W magnitude distribution and NIRCam colours with observations. We find that the predicted and observed magnitude distributions are similar, at least at 5<z<8. At z>8 the distributions differ somewhat, though our observed sample size is small and thus susceptible to statistical fluctuations. Likewise, the predicted and observed colour evolution show broad agreement, at least at 5<z<8. There is however some disagreement between the observed and modelled strength of the strong line contribution. In particular all the models fails to reproduce the F410M-F444W colour at z>8, though, again, the sample size is small here.

We conduct an extended analysis of dark energy constraints, in support of the findings of the DESI DR2 cosmology key paper, including DESI data, Planck CMB observations, and three different supernova compilations. Using a broad range of parametric and non-parametric methods, we explore the dark energy phenomenology and find consistent trends across all approaches, in good agreement with the w_0w_aCDM key paper results. Even with the additional flexibility introduced by non-parametric approaches, such as binning and Gaussian Processes, we find that extending LambdaCDM to include a two-parameter w(z) is sufficient to capture the trends present in the data. Finally, we examine three dark energy classes with distinct dynamics, including quintessence scenarios satisfying w geq -1, to explore what underlying physics can explain such deviations. The current data indicate a clear preference for models that feature a phantom crossing; although alternatives lacking this feature are disfavored, they cannot yet be ruled out. Our analysis confirms that the evidence for dynamical dark energy, particularly at low redshift (z lesssim 0.3), is robust and stable under different modeling choices.

JWST has now made it possible to probe the rest-frame optical line emission of high-redshift galaxies extending to z~9, and potentially beyond. To aid in the interpretation of these emerging constraints, in this work we explore predictions for [OIII] emission in high-redshift galaxies using the First Light and Reionisation Epoch Simulations (FLARES). We produce predictions for the [OIII] luminosity function, its correlation with the UV luminosity, and the distribution of equivalent widths (EWs). We also explore how the [OIII] EW correlates with physical properties including specific star formation rate, metallicity, and dust attenuation. Our predictions are largely consistent with recent observational constraints on the luminosity function, average equivalent widths, and line ratios. However, they fail to reproduce the observed tail of high-EW sources and the number density of extreme line emitters. Possibilities to explain these discrepancies include an additional source of ionising photons and/or greater stochasticity in star formation in the model or photometric scatter and/or bias in the observations. With JWST now rapidly building larger samples and a wider range of emission lines the answer to this remaining discrepancy should be available imminently.

We introduce our first-generation reasoning models, DeepSeek-R1-Zero and DeepSeek-R1. DeepSeek-R1-Zero, a model trained via large-scale reinforcement learning (RL) without supervised fine-tuning (SFT) as a preliminary step, demonstrates remarkable reasoning capabilities. Through RL, DeepSeek-R1-Zero naturally emerges with numerous powerful and intriguing reasoning behaviors. However, it encounters challenges such as poor readability, and language mixing. To address these issues and further enhance reasoning performance, we introduce DeepSeek-R1, which incorporates multi-stage training and cold-start data before RL. DeepSeek-R1 achieves performance comparable to OpenAI-o1-1217 on reasoning tasks. To support the research community, we open-source DeepSeek-R1-Zero, DeepSeek-R1, and six dense models (1.5B, 7B, 8B, 14B, 32B, 70B) distilled from DeepSeek-R1 based on Qwen and Llama.

Gravitational lensing offers a powerful probe into the properties of dark matter and is crucial to infer cosmological parameters. The Legacy Survey of Space and Time (LSST) is predicted to find O(10^5) gravitational lenses over the next decade, demanding automated classifiers. In this work, we introduce GraViT, a PyTorch pipeline for gravitational lens detection that leverages extensive pretraining of state-of-the-art Vision Transformer (ViT) models and MLP-Mixer. We assess the impact of transfer learning on classification performance by examining data quality (source and sample size), model architecture (selection and fine-tuning), training strategies (augmentation, normalization, and optimization), and ensemble predictions. This study reproduces the experiments in a previous systematic comparison of neural networks and provides insights into the detectability of strong gravitational lenses on that common test sample. We fine-tune ten architectures using datasets from HOLISMOKES VI and SuGOHI X, and benchmark them against convolutional baselines, discussing complexity and inference-time analysis.

The upcoming space-based gravitational wave (GW) observatory, LISA, is expected to detect GW signals from supermassive black hole (SMBH) mergers occurring at high redshifts. However, understanding the origin and growth of SMBHs in the early Universe remains an open problem in astrophysics. In this work, we utilize the First Light And Reionization Epoch Simulations (FLARES), a suite of cosmological hydrodynamical zoom-in simulations, to study SMBH mergers at 5 lesssim z lesssim 10 across a wide range of environments. Most mergers in FLARES involve secondary SMBHs near the seed mass (m_{seed} approx 1.5 times 10^{5} M_{odot}) while primary SMBHs span up to 10^{9} M_{odot}, resulting in mass ratios from q sim 10^{-4} to 1, with a peak at q sim 1. The number of mergers increases rapidly towards lower redshifts, and the comoving total number density scales with overdensity as n_{merger} = 10^{-3.80} (1 + delta)^{4.56}. Denser regions host more massive mergers, with higher merger redshifts and lower mass ratios. Within the FLARES redshift range, LISA is expected to detect mergers with 10^{5} lesssim M_{tot} / M_{odot} lesssim 10^{8} and q gtrsim 10^{-2}, corresponding to a detection rate of 0.030 yr^{-1} for events with signal-to-noise ratio SNR geq 10. Our study demonstrates the sensitivity of GW predictions at high redshifts to SMBH seed models and merger time delays, highlighting the need for improved modeling in future cosmological simulations to maximize LISA's scientific return.

We present a detailed visual morphology catalogue for Euclid's Quick Release 1 (Q1). Our catalogue includes galaxy features such as bars, spiral arms, and ongoing mergers, for the 378000 bright (IE < 20.5) or extended (area geq 700,pixels) galaxies in Q1. The catalogue was created by finetuning the Zoobot galaxy foundation models on annotations from an intensive one month campaign by Galaxy Zoo volunteers. Our measurements are fully automated and hence fully scaleable. This catalogue is the first 0.4% of the approximately 100 million galaxies where Euclid will ultimately resolve detailed morphology.

Statistics that capture the directional dependence of the baryon distribution in the cosmic web enable unique tests of cosmology and astrophysical feedback. We use constrained oriented stacking of thermal Sunyaev-Zel'dovich (tSZ) maps to measure the anisotropic distribution of hot gas 2.5-40 Mpc away from galaxy clusters embedded in massive filaments and superclusters. The cluster selection and orientation (at a scale of sim15 Mpc) use Dark Energy Survey (DES) Year 3 data, while expanded tSZ maps from the Atacama Cosmology Telescope Data Release 6 enable a sim3times more significant measurement of the extended gas compared to the technique's proof-of-concept. Decomposing stacks into cosine multipoles of order m, we detect a dipole (m=1) and quadrupole (m=2) at 8-10sigma, as well as evidence for m=4 signal at up to 6sigma, indicating sensitivity to late-time non-Gaussianity. We compare to the Cardinal simulations with spherical gas models pasted onto dark matter halos. The fiducial tSZ data can discriminate between two models that deplete pressure differently in low-mass halos (mimicking astrophysical feedback), preferring higher average pressure in extended structures. However, uncertainty in the amount of cosmic infrared background contamination reduces the constraining power. Additionally, we apply the technique to DES galaxy density and weak lensing to study for the first time their oriented relationships with tSZ. In the tSZ-to-lensing relation, averaged on 7.5 Mpc (transverse) scales, we observe dependence on redshift but not shape or radial distance. Thus, on large scales, the superclustering of gas pressure, galaxies, and total matter is coherent in shape and extent.

In contrast to classical reinforcement learning, distributional reinforcement learning algorithms aim to learn the distribution of returns rather than their expected value. Since the nature of the return distribution is generally unknown a priori or arbitrarily complex, a common approach finds approximations within a set of representable, parametric distributions. Typically, this involves a projection of the unconstrained distribution onto the set of simplified distributions. We argue that this projection step entails a strong inductive bias when coupled with neural networks and gradient descent, thereby profoundly impacting the generalization behavior of learned models. In order to facilitate reliable uncertainty estimation through diversity, this work studies the combination of several different projections and representations in a distributional ensemble. We establish theoretical properties of such projection ensembles and derive an algorithm that uses ensemble disagreement, measured by the average 1-Wasserstein distance, as a bonus for deep exploration. We evaluate our algorithm on the behavior suite benchmark and find that diverse projection ensembles lead to significant performance improvements over existing methods on a wide variety of tasks with the most pronounced gains in directed exploration problems.

Space biology research aims to understand fundamental effects of spaceflight on organisms, develop foundational knowledge to support deep space exploration, and ultimately bioengineer spacecraft and habitats to stabilize the ecosystem of plants, crops, microbes, animals, and humans for sustained multi-planetary life. To advance these aims, the field leverages experiments, platforms, data, and model organisms from both spaceborne and ground-analog studies. As research is extended beyond low Earth orbit, experiments and platforms must be maximally autonomous, light, agile, and intelligent to expedite knowledge discovery. Here we present a summary of recommendations from a workshop organized by the National Aeronautics and Space Administration on artificial intelligence, machine learning, and modeling applications which offer key solutions toward these space biology challenges. In the next decade, the synthesis of artificial intelligence into the field of space biology will deepen the biological understanding of spaceflight effects, facilitate predictive modeling and analytics, support maximally autonomous and reproducible experiments, and efficiently manage spaceborne data and metadata, all with the goal to enable life to thrive in deep space.

Audio-driven human animation technology is widely used in human-computer interaction, and the emergence of diffusion models has further advanced its development. Currently, most methods rely on multi-stage generation and intermediate representations, resulting in long inference time and issues with generation quality in specific foreground regions and audio-motion consistency. These shortcomings are primarily due to the lack of localized fine-grained supervised guidance. To address above challenges, we propose Parts-aware Audio-driven Human Animation, PAHA, a unit enhancement and guidance framework for audio-driven upper-body animation. We introduce two key methods: Parts-Aware Re-weighting (PAR) and Parts Consistency Enhancement (PCE). PAR dynamically adjusts regional training loss weights based on pose confidence scores, effectively improving visual quality. PCE constructs and trains diffusion-based regional audio-visual classifiers to improve the consistency of motion and co-speech audio. Afterwards, we design two novel inference guidance methods for the foregoing classifiers, Sequential Guidance (SG) and Differential Guidance (DG), to balance efficiency and quality respectively. Additionally, we build CNAS, the first public Chinese News Anchor Speech dataset, to advance research and validation in this field. Extensive experimental results and user studies demonstrate that PAHA significantly outperforms existing methods in audio-motion alignment and video-related evaluations. The codes and CNAS dataset will be released upon acceptance.

The Euclid satellite is an ESA mission that was launched in July 2023. \Euclid is working in its regular observing mode with the target of observing an area of 14,000~deg^2 with two instruments, the Visible Camera (VIS) and the Near IR Spectrometer and Photometer (NISP) down to I_{rm E} = 24.5~mag (10, sigma) in the Euclid Wide Survey. Ground-based imaging data in the ugriz bands complement the \Euclid data to enable photo-z determination and VIS PSF modeling for week lensing analysis. Euclid investigates the distance-redshift relation and the evolution of cosmic structures by measuring shapes and redshifts of galaxies and clusters of galaxies out to zsim 2. Generating the multi-wavelength catalogues from \Euclid and ground-based data is an essential part of the \Euclid data processing system. In the framework of the \Euclid Science Ground Segment (SGS), the aim of the MER Processing Function (PF) pipeline is to detect objects in the \Euclid imaging data, measure their properties, and MERge them into a single multi-wavelength catalogue. The MER PF pipeline performs source detection on both visible (VIS) and near-infrared (NIR) images and offers four different photometric measurements: Kron total flux, aperture photometry on PSF-matched images, template fitting photometry, and S\'ersic fitting photometry. Furthermore, the MER PF pipeline measures a set of ancillary quantities, spanning from morphology to quality flags, to better characterise all detected sources. In this paper, we show how the MER PF pipeline is designed, detailing its main steps, and we show that the pipeline products meet the tight requirements that Euclid aims to achieve on photometric accuracy. We also present the other measurements (e.g. morphology) that are included in the OU-MER output catalogues and we list all output products coming out of the MER PF pipeline.

We present a search for the diffuse extremely-high-energy neutrino flux using 12.6 years of IceCube data. The non-observation of neutrinos with energies well above 10 , PeV constrains the all-flavor neutrino flux at 10^{18} , eV to a level of E^2 Phi_{nu_e + nu_mu + nu_tau} simeq 10^{-8} , GeV , cm^{-2} , s^{-1} , sr^{-1}, the most stringent limit to date. Using this data, we constrain the proton fraction of ultra-high-energy cosmic rays (UHECRs) above simeq 30 , EeV to be lesssim 70,% (at 90,% CL) if the cosmological evolution of the sources is comparable to or stronger than the star formation rate. This result complements direct air-shower measurements by being insensitive to uncertainties associated with hadronic interaction models. It is the first such result to disfavor the ``proton-only" hypothesis for UHECRs using neutrino data.

An amplitude analysis of B^-rightarrow D^- D^0 K_S^0 decays is performed using proton-proton collision data, corresponding to an integrated luminosity of 9,fb^{-1}, collected with the LHCb detector at center-of-mass energies of 7, 8, and 13,Tekern -0.1em V. A resonant structure of spin-parity 0^+ is observed in the D^0 K_S^0 invariant-mass spectrum with a significance of 5.3,sigma. The mass and width of the state, modeled with a Breit-Wigner lineshape, are determined to be 2883pm11pm6,Mekern -0.1em V!/c^2 and 87_{-47}^{+22}pm6,Mekern -0.1em V respectively, where the first uncertainties are statistical and the second systematic. These properties and the quark content are consistent with those of the open-charm tetraquark state T_{cs 0}^{*}(2870)^0 observed previously in the D^+ K^- final state of the B^-rightarrow D^- D^+ K^- decay. This result confirms the existence of the T_{cs 0}^{*}(2870)^0 state in a new decay mode. The T_{cs1}^{*}(2900)^0 state, reported in the B^-rightarrow D^- D^+ K^- decay, is also searched for in the D^0 K_S^0 invariant-mass spectrum of the B^- rightarrow D^- D^0 K_S^0 decay, without finding evidence for it.

Using the First Light And Reionisation Epoch Simulations ({rm F{small LARES}}), a suite of hydrodynamical simulations we explore the consequences of a realistic model for star--dust geometry on the observed properties of galaxies. We find that the UV attenuation declines rapidly from the central regions of galaxies, and bright galaxies have spatially extended star formation that suffers less obscuration than their fainter counterparts, demonstrating a non-linear relationship between the UV luminosity and the UV attenuation, giving a double power-law shape to the UVLF. Spatially distinct stellar populations within galaxies experience a wide range of dust attenuation due to variations in the dust optical depth along their line-of-sight; which can range from completely dust obscured to being fully unobscured. The overall attenuation curve of a galaxy is then a complex combination of various lines-of-sight within the galaxy. We explore the manifestation of this effect to study the reliability of line ratios to infer galaxy properties, in particular the Balmer decrement and the BPT diagram. We find the Balmer decrement predicted Balmer line attenuation to be higher (factor of 1 to gtrsim10) than expected from commonly used attenuation curves. The observed BPT line ratios deviate from their intrinsic values (median difference of 0.08 (0.02) and standard deviation of 0.2 (0.05) for log_{10}([N{small II}]lambda 6585/H_{alpha}) (log_{10}([O{small III}]lambda 5008/H_{beta})). Finally, we explore the variation in observed properties (UV attenuation, UV slope and Balmer decrement) with viewing angle, finding average differences of sim0.3 magnitudes in the UV attenuation.

Theano is a Python library that allows to define, optimize, and evaluate mathematical expressions involving multi-dimensional arrays efficiently. Since its introduction, it has been one of the most used CPU and GPU mathematical compilers - especially in the machine learning community - and has shown steady performance improvements. Theano is being actively and continuously developed since 2008, multiple frameworks have been built on top of it and it has been used to produce many state-of-the-art machine learning models. The present article is structured as follows. Section I provides an overview of the Theano software and its community. Section II presents the principal features of Theano and how to use them, and compares them with other similar projects. Section III focuses on recently-introduced functionalities and improvements. Section IV compares the performance of Theano against Torch7 and TensorFlow on several machine learning models. Section V discusses current limitations of Theano and potential ways of improving it.

We present a spectroscopic analysis of two star-forming galaxies at z~5 observed with JWST/NIRSpec as part of the Early eXtragalactic Continuum and Emission Line Science (EXCELS) survey. The detection of the C III]lambdalambda1906,09, [O II]lambdalambda3726,29, [O III]lambdalambda4363,5007, and [N II]lambda6584 nebular emission lines enables investigation of the C/O, N/O, and C/N abundance ratios using the temperature-sensitive method. The two galaxies have stellar masses of log(M_{star}/M_{odot} ) = 8.13pm0.09 and log(M_{star}/M_{odot} )=8.52pm0.13 and corresponding metallicities of Z~0.2Z_{odot} and Z~0.3Z_{odot}. These metallicities are somewhat higher than is typical for other z>5 galaxies with similar stellar mass and are in fact comparable to high-redshift analogue galaxies at z~0. Both galaxies display evidence for N/O enhancement with respect to the z~0 sample, with log(N/O)=-1.07pm0.17 and log(N/O)=-0.86pm0.15 respectively. In contrast, we find low C abundances, with log(C/O)=-0.82pm0.22 and log(C/O)=-1.02pm0.22, consistent with the predicted yields of core-collapse supernovae. Following the trend observed in other high-redshift sources, we find that the C/N ratios are lower at fixed O/H compared to the majority of local galaxies. In contrast to the top-heavy IMF invoked in some studies to explain low C/N ratios in metal-poor galaxies, we find, via comparison to chemical evolution models, that a standard or bottom-heavy IMF better explains the observed abundance ratios in more enriched systems due to an increase in N-enrichment from intermediate mass (4-7M_{odot}) stars. Our results demonstrate that robust measurements of CNO abundances with JWST can reveal unique enrichment pathways in galaxies as a function of both metallicity and redshift.

Benchmarks are important tools for tracking the rapid advancements in large language model (LLM) capabilities. However, benchmarks are not keeping pace in difficulty: LLMs now achieve over 90\% accuracy on popular benchmarks like MMLU, limiting informed measurement of state-of-the-art LLM capabilities. In response, we introduce Humanity's Last Exam (HLE), a multi-modal benchmark at the frontier of human knowledge, designed to be the final closed-ended academic benchmark of its kind with broad subject coverage. HLE consists of 3,000 questions across dozens of subjects, including mathematics, humanities, and the natural sciences. HLE is developed globally by subject-matter experts and consists of multiple-choice and short-answer questions suitable for automated grading. Each question has a known solution that is unambiguous and easily verifiable, but cannot be quickly answered via internet retrieval. State-of-the-art LLMs demonstrate low accuracy and calibration on HLE, highlighting a significant gap between current LLM capabilities and the expert human frontier on closed-ended academic questions. To inform research and policymaking upon a clear understanding of model capabilities, we publicly release HLE at https://lastexam.ai.

Data augmentation is an important component in the robustness evaluation of models in natural language processing (NLP) and in enhancing the diversity of the data they are trained on. In this paper, we present NL-Augmenter, a new participatory Python-based natural language augmentation framework which supports the creation of both transformations (modifications to the data) and filters (data splits according to specific features). We describe the framework and an initial set of 117 transformations and 23 filters for a variety of natural language tasks. We demonstrate the efficacy of NL-Augmenter by using several of its transformations to analyze the robustness of popular natural language models. The infrastructure, datacards and robustness analysis results are available publicly on the NL-Augmenter repository (https://github.com/GEM-benchmark/NL-Augmenter).

This article presents a review about the main CERN n\_TOF contributions to the field of neutron-capture experiments of interest for s-process nucleosynthesis studies over the last 25 years, with special focus on the measurement of radioactive isotopes. A few recent capture experiments on stable isotopes of astrophysical interest are also discussed. Results on s-process branching nuclei are appropriate to illustrate how advances in detection systems and upgrades in the facility have enabled increasingly challenging experiments and, as a consequence, have led to a better understanding and modeling of the s-process mechanism of nucleosynthesis. New endeavors combining radioactive-ion beams from ISOLDE for the production of radioisotopically pure samples for activation experiments at the new NEAR facility at n\_TOF are briefly discussed. On the basis of these new exciting results, also current limitations of state-of-the-art TOF and activation techniques will be depicted, thereby showing the pressing need for further upgrades and enhancements on both facilities and detection systems. A brief account of the potential technique based on inverse kinematics for direct neutron-capture measurements is also presented.

We present the findings of "The Alzheimer's Disease Prediction Of Longitudinal Evolution" (TADPOLE) Challenge, which compared the performance of 92 algorithms from 33 international teams at predicting the future trajectory of 219 individuals at risk of Alzheimer's disease. Challenge participants were required to make a prediction, for each month of a 5-year future time period, of three key outcomes: clinical diagnosis, Alzheimer's Disease Assessment Scale Cognitive Subdomain (ADAS-Cog13), and total volume of the ventricles. The methods used by challenge participants included multivariate linear regression, machine learning methods such as support vector machines and deep neural networks, as well as disease progression models. No single submission was best at predicting all three outcomes. For clinical diagnosis and ventricle volume prediction, the best algorithms strongly outperform simple baselines in predictive ability. However, for ADAS-Cog13 no single submitted prediction method was significantly better than random guesswork. Two ensemble methods based on taking the mean and median over all predictions, obtained top scores on almost all tasks. Better than average performance at diagnosis prediction was generally associated with the additional inclusion of features from cerebrospinal fluid (CSF) samples and diffusion tensor imaging (DTI). On the other hand, better performance at ventricle volume prediction was associated with inclusion of summary statistics, such as the slope or maxima/minima of biomarkers. TADPOLE's unique results suggest that current prediction algorithms provide sufficient accuracy to exploit biomarkers related to clinical diagnosis and ventricle volume, for cohort refinement in clinical trials for Alzheimer's disease. However, results call into question the usage of cognitive test scores for patient selection and as a primary endpoint in clinical trials.

As models grow more capable, human supervision breaks down: labels don't scale, outputs can be gamed, and training doesn't generalize. Scalable oversight requires steering methods that are internal, self-supervised, and transfer out-of-distribution; existing methods satisfy some but not all three. We introduce AntiPaSTO, which separates representations along an anti-parallel axis (α=pm1 produce opposite shifts), with coherence constraints preventing collapse. Human input is minimal: two contrasting words inserted into template sentences, no preference labels. Using 800 such pairs on Gemma-3-1B, AntiPaSTO beats prompting baselines by 6.9times on DailyDilemmas and maintains bidirectional control where prompting triggers refusal. Code is available at https://github.com/wassname/AntiPaSTO.

This study presents an automated lameness detection system that uses deep-learning image processing techniques to extract multiple locomotion traits associated with lameness. Using the T-LEAP pose estimation model, the motion of nine keypoints was extracted from videos of walking cows. The videos were recorded outdoors, with varying illumination conditions, and T-LEAP extracted 99.6% of correct keypoints. The trajectories of the keypoints were then used to compute six locomotion traits: back posture measurement, head bobbing, tracking distance, stride length, stance duration, and swing duration. The three most important traits were back posture measurement, head bobbing, and tracking distance. For the ground truth, we showed that a thoughtful merging of the scores of the observers could improve intra-observer reliability and agreement. We showed that including multiple locomotion traits improves the classification accuracy from 76.6% with only one trait to 79.9% with the three most important traits and to 80.1% with all six locomotion traits.

Vision Transformer (ViT) has emerged as a prominent backbone for computer vision. For more efficient ViTs, recent works lessen the quadratic cost of the self-attention layer by pruning or fusing the redundant tokens. However, these works faced the speed-accuracy trade-off caused by the loss of information. Here, we argue that token fusion needs to consider diverse relations between tokens to minimize information loss. In this paper, we propose a Multi-criteria Token Fusion (MCTF), that gradually fuses the tokens based on multi-criteria (e.g., similarity, informativeness, and size of fused tokens). Further, we utilize the one-step-ahead attention, which is the improved approach to capture the informativeness of the tokens. By training the model equipped with MCTF using a token reduction consistency, we achieve the best speed-accuracy trade-off in the image classification (ImageNet1K). Experimental results prove that MCTF consistently surpasses the previous reduction methods with and without training. Specifically, DeiT-T and DeiT-S with MCTF reduce FLOPs by about 44% while improving the performance (+0.5%, and +0.3%) over the base model, respectively. We also demonstrate the applicability of MCTF in various Vision Transformers (e.g., T2T-ViT, LV-ViT), achieving at least 31% speedup without performance degradation. Code is available at https://github.com/mlvlab/MCTF.

Vision-as-inverse-graphics, the concept of reconstructing an image as an editable graphics program is a long-standing goal of computer vision. Yet even strong VLMs aren't able to achieve this in one-shot as they lack fine-grained spatial and physical grounding capability. Our key insight is that closing this gap requires interleaved multimodal reasoning through iterative execution and verification. Stemming from this, we present VIGA (Vision-as-Inverse-Graphic Agent) that starts from an empty world and reconstructs or edits scenes through a closed-loop write-run-render-compare-revise procedure. To support long-horizon reasoning, VIGA combines (i) a skill library that alternates generator and verifier roles and (ii) an evolving context memory that contains plans, code diffs, and render history. VIGA is task-agnostic as it doesn't require auxiliary modules, covering a wide range of tasks such as 3D reconstruction, multi-step scene editing, 4D physical interaction, and 2D document editing, etc. Empirically, we found VIGA substantially improves one-shot baselines on BlenderGym (35.32%) and SlideBench (117.17%). Moreover, VIGA is also model-agnostic as it doesn't require finetuning, enabling a unified protocol to evaluate heterogeneous foundation VLMs. To better support this protocol, we introduce BlenderBench, a challenging benchmark that stress-tests interleaved multimodal reasoning with graphics engine, where VIGA improves by 124.70%.

We present the third data release of the European Space Agency's Gaia mission, GDR3. The GDR3 catalogue is the outcome of the processing of raw data collected with the Gaia instruments during the first 34 months of the mission by the Gaia Data Processing and Analysis Consortium. The GDR3 catalogue contains the same source list, celestial positions, proper motions, parallaxes, and broad band photometry in the G, G_{BP}, and G_{RP} pass-bands already present in the Early Third Data Release. GDR3 introduces an impressive wealth of new data products. More than 33 million objects in the ranges G_{rvs} < 14 and 3100 <T_{eff} <14500 , have new determinations of their mean radial velocities based on data collected by Gaia. We provide G_{rvs} magnitudes for most sources with radial velocities, and a line broadening parameter is listed for a subset of these. Mean Gaia spectra are made available to the community. The GDR3 catalogue includes about 1 million mean spectra from the radial velocity spectrometer, and about 220 million low-resolution blue and red prism photometer BPRP mean spectra. The results of the analysis of epoch photometry are provided for some 10 million sources across 24 variability types. GDR3 includes astrophysical parameters and source class probabilities for about 470 million and 1500 million sources, respectively, including stars, galaxies, and quasars. Orbital elements and trend parameters are provided for some 800,000 astrometric, spectroscopic and eclipsing binaries. More than 150,000 Solar System objects, including new discoveries, with preliminary orbital solutions and individual epoch observations are part of this release. Reflectance spectra derived from the epoch BPRP spectral data are published for about 60\,000 asteroids. Finally, an additional data set is provided, namely the Gaia Andromeda Photometric Survey (abridged)

We show, for the first time, radio measurements of the depth of shower maximum (X_max) of air showers induced by cosmic rays that are compared to measurements of the established fluorescence method at the same location. Using measurements at the Pierre Auger Observatory we show full compatibility between our radio and the previously published fluorescence data set, and between a subset of air showers observed simultaneously with both radio and fluorescence techniques, a measurement setup unique to the Pierre Auger Observatory. Furthermore, we show radio X_max resolution as a function of energy and demonstrate the ability to make competitive high-resolution X_max measurements with even a sparse radio array. With this, we show that the radio technique is capable of cosmic-ray mass composition studies, both at Auger and at other experiments.

This paper documents the seventeenth data release (DR17) from the Sloan Digital Sky Surveys; the fifth and final release from the fourth phase (SDSS-IV). DR17 contains the complete release of the Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey, which reached its goal of surveying over 10,000 nearby galaxies. The complete release of the MaNGA Stellar Library (MaStar) accompanies this data, providing observations of almost 30,000 stars through the MaNGA instrument during bright time. DR17 also contains the complete release of the Apache Point Observatory Galactic Evolution Experiment 2 (APOGEE-2) survey which publicly releases infra-red spectra of over 650,000 stars. The main sample from the Extended Baryon Oscillation Spectroscopic Survey (eBOSS), as well as the sub-survey Time Domain Spectroscopic Survey (TDSS) data were fully released in DR16. New single-fiber optical spectroscopy released in DR17 is from the SPectroscipic IDentification of ERosita Survey (SPIDERS) sub-survey and the eBOSS-RM program. Along with the primary data sets, DR17 includes 25 new or updated Value Added Catalogs (VACs). This paper concludes the release of SDSS-IV survey data. SDSS continues into its fifth phase with observations already underway for the Milky Way Mapper (MWM), Local Volume Mapper (LVM) and Black Hole Mapper (BHM) surveys.

The coldest Y spectral type brown dwarfs are similar in mass and temperature to cool and warm (sim200 -- 400 K) giant exoplanets. We can therefore use their atmospheres as proxies for planetary atmospheres, testing our understanding of physics and chemistry for these complex, cool worlds. At these cold temperatures, their atmospheres are cold enough for water clouds to form, and chemical timescales increase, increasing the likelihood of disequilibrium chemistry compared to warmer classes of planets. JWST observations are revolutionizing the characterization of these worlds with high signal-to-noise, moderate resolution near- and mid-infrared spectra. The spectra have been used to measure the abundances of prominent species like water, methane, and ammonia; species that trace chemical reactions like carbon monoxide; and even isotopologues of carbon monoxide and ammonia. Here, we present atmospheric retrieval results using both published fixed-slit (GTO program 1230) and new averaged time series observations (GO program 2327) of the coldest known Y dwarf, WISE 0855-0714 (using NIRSpec G395M spectra), which has an effective temperature of sim 264 K. We present a detection of deuterium in an atmosphere outside of the solar system via a relative measurement of deuterated methane (CH_{3}D) and standard methane. From this, we infer the D/H ratio of a substellar object outside the solar system for the first time. We also present a well-constrained part-per-billion abundance of phosphine (PH_{3}). We discuss our interpretation of these results and the implications for brown dwarf and giant exoplanet formation and evolution.

Computational measurement of human behavior from video has recently become feasible due to major advances in AI. These advances now enable granular and precise quantification of facial expression, head movement, body action, and other behavioral modalities and are increasingly used in psychology, psychiatry, neuroscience, and mental health research. However, mainstream adoption remains slow. Most existing methods and software are developed for engineering audiences, require specialized software stacks, and fail to provide behavioral measurements at a level directly useful for hypothesis-driven research. As a result, there is a large barrier to entry for researchers who wish to use modern, AI-based tools in their work. We introduce Bitbox, an open-source toolkit designed to remove this barrier and make advanced computational analysis directly usable by behavioral scientists and clinical researchers. Bitbox is guided by principles of reproducibility, modularity, and interpretability. It provides a standardized interface for extracting high-level behavioral measurements from video, leveraging multiple face, head, and body processors. The core modules have been tested and validated on clinical samples and are designed so that new measures can be added with minimal effort. Bitbox is intended to serve both sides of the translational gap. It gives behavioral researchers access to robust, high-level behavioral metrics without requiring engineering expertise, and it provides computer scientists a practical mechanism for disseminating methods to domains where their impact is most needed. We expect that Bitbox will accelerate integration of computational behavioral measurement into behavioral, clinical, and mental health research. Bitbox has been designed from the beginning as a community-driven effort that will evolve through contributions from both method developers and domain scientists.

Based on the established task of identifying boosted, hadronically decaying top quarks, we compare a wide range of modern machine learning approaches. Unlike most established methods they rely on low-level input, for instance calorimeter output. While their network architectures are vastly different, their performance is comparatively similar. In general, we find that these new approaches are extremely powerful and great fun.

The last decade has seen a marked shift in how the internal structure of hadrons is understood. Modern experimental facilities, new theoretical techniques for the continuum bound-state problem and progress with lattice-regularised QCD have provided strong indications that soft quark+quark (diquark) correlations play a crucial role in hadron physics. For example, theory indicates that the appearance of such correlations is a necessary consequence of dynamical chiral symmetry breaking, viz. a corollary of emergent hadronic mass that is responsible for almost all visible mass in the universe; experiment has uncovered signals for such correlations in the flavour-separation of the proton's electromagnetic form factors; and phenomenology suggests that diquark correlations might be critical to the formation of exotic tetra- and penta-quark hadrons. A broad spectrum of such information is evaluated herein, with a view to consolidating the facts and therefrom moving toward a coherent, unified picture of hadron structure and the role that diquark correlations might play.

We investigate the correlation between stellar mass (M*) and star formation rate (SFR) across the stellar mass range log10(M*/Msun)~6-11. We consider almost 50,000 star-forming galaxies at z~3-7, leveraging data from COSMOS/SMUVS, JADES/GOODS-SOUTH, and MIDIS/XDF. This is the first study spanning such a wide stellar mass range without relying on gravitational lensing effects. We locate our galaxies on the SFR-M* plane to assess how the location of galaxies in the star-formation main sequence (MS) and starburst (SB) region evolves with stellar mass and redshift. We find that the two star-forming modes tend to converge at log10(M*/Msun) < 7, with all galaxies found in the SB mode. However, deeper observations will be instrumental for reaching lower SFRs and Msun to further validate this scenario. By dissecting our galaxy sample in stellar mass and redshift, we show that the emergence of the star-formation MS is stellar-mass dependent: while in galaxies with log10(M*/Msun) > 9 the MS is already well in place at z = 5-7, for galaxies with log10(M*/Msun)~7-8 it only becomes significant at z<4. Overall, our results are in line with previous findings that the SB mode dominates amongst low stellar-mass galaxies. The earlier emergence of the MS for massive galaxies is consistent with galaxy downsizing.

The steady-state gamma-ray emission from the Sun is thought to consist of two emission components due to interactions with Galactic cosmic rays: (1) a hadronic component covering the solar disk, and (2) a leptonic component peaking at the solar edge and extending into the heliosphere. The flux of these components is expected to vary with the 11-year solar cycle, being highest during solar minimum and lowest during solar maximum, because it is correlated with the cosmic-ray flux. No study has yet analyzed the flux variation of the two components separately over solar cycles. In this work, we measure the temporal variations of the flux of each component over 15 years of Fermi Large Area Telescope observations and compare them with the sunspot number and Galactic cosmic-ray flux from AMS-02 near the Earth. We find that the flux variation of the disk anticorrelates with solar activity and correlates with cosmic-ray protons, confirming its emission mechanism. The flux variation of the extended component anticorrelates with solar activity only until mid 2012. After that, we no longer observe any correlation or anticorrelation, even with the CR electron flux. This most likely suggests that cosmic-ray transport and modulation in the inner heliosphere are unexpectedly complex and different for electrons and protons or, alternatively, the presence of an additional, unknown component of gamma rays or cosmic rays. These findings impact space weather research and emphasize the need for close monitoring of Cycle 25 and the ongoing polarity reversal.

At a fraction the total cost of an equivalent orbital mission, scientific balloon-borne platforms, operating above 99.7% of the Earth's atmosphere, offer attractive, competitive, and effective observational capabilities -- namely space-like resolution, transmission, and backgrounds -- that are well suited for modern astronomy and cosmology. SuperBIT is a diffraction-limited, wide-field, 0.5 m telescope capable of exploiting these observing conditions in order to provide exquisite imaging throughout the near-IR to near-UV. It utilizes a robust active stabilization system that has consistently demonstrated a 1 sigma sky-fixed pointing stability at 48 milliarcseconds over multiple 1 hour observations at float. This is achieved by actively tracking compound pendulations via a three-axis gimballed platform, which provides sky-fixed telescope stability at < 500 milliarcseconds and corrects for field rotation, while employing high-bandwidth tip/tilt optics to remove residual disturbances across the science imaging focal plane. SuperBIT's performance during the 2019 commissioning flight benefited from a customized high-fidelity science-capable telescope designed with exceptional thermo- and opto-mechanical stability as well as tightly constrained static and dynamic coupling between high-rate sensors and telescope optics. At the currently demonstrated level of flight performance, SuperBIT capabilities now surpass the science requirements for a wide variety of experiments in cosmology, astrophysics and stellar dynamics.

We present the requirements, design and evaluation of the cryogenic continuously rotating half-wave plate (CHWP) for the Simons Observatory (SO). SO is a cosmic microwave background (CMB) polarization experiment at Parque Astron\'{o}mico Atacama in northern Chile that covers a wide range of angular scales using both small (0.42 m) and large (6 m) aperture telescopes. In particular, the small aperture telescopes (SATs) focus on large angular scales for primordial B-mode polarization. To this end, the SATs employ a CHWP to modulate the polarization of the incident light at 8 Hz, suppressing atmospheric 1/f noise and mitigating systematic uncertainties that would otherwise arise due to the differential response of detectors sensitive to orthogonal polarizations. The CHWP consists of a 505 mm diameter achromatic sapphire HWP and a cryogenic rotation mechanism, both of which are cooled down to sim50 K to reduce detector thermal loading. Under normal operation the HWP is suspended by a superconducting magnetic bearing and rotates with a constant 2 Hz frequency, controlled by an electromagnetic synchronous motor. We find that the number of superconductors and magnets that make up the superconducting magnetic bearing are important design parameters, especially for the rotation mechanism's vibration performance. The rotation angle is detected through an angular encoder with a noise level of 0.07 muradmathrm{s}. During a cooldown, the rotor is held in place by a grip-and-release mechanism that serves as both an alignment device and a thermal path. In this paper we provide an overview of the SO SAT CHWP: its requirements, hardware design, and laboratory performance.

The Superpressure Balloon-borne Imaging Telescope (SuperBIT) is a diffraction-limited, wide-field, 0.5 m, near-infrared to near-ultraviolet observatory designed to exploit the stratosphere's space-like conditions. SuperBIT's 2023 science flight will deliver deep, blue imaging of galaxy clusters for gravitational lensing analysis. In preparation, we have developed a weak lensing measurement pipeline with modern algorithms for PSF characterization, shape measurement, and shear calibration. We validate our pipeline and forecast SuperBIT survey properties with simulated galaxy cluster observations in SuperBIT's near-UV and blue bandpasses. We predict imaging depth, galaxy number (source) density, and redshift distribution for observations in SuperBIT's three bluest filters; the effect of lensing sample selections is also considered. We find that in three hours of on-sky integration, SuperBIT can attain a depth of b = 26 mag and a total source density exceeding 40 galaxies per square arcminute. Even with the application of lensing-analysis catalog selections, we find b-band source densities between 25 and 30 galaxies per square arcminute with a median redshift of z = 1.1. Our analysis confirms SuperBIT's capability for weak gravitational lensing measurements in the blue.

Lack of rigorous reproducibility and validation are major hurdles for scientific development across many fields. Materials science in particular encompasses a variety of experimental and theoretical approaches that require careful benchmarking. Leaderboard efforts have been developed previously to mitigate these issues. However, a comprehensive comparison and benchmarking on an integrated platform with multiple data modalities with both perfect and defect materials data is still lacking. This work introduces JARVIS-Leaderboard, an open-source and community-driven platform that facilitates benchmarking and enhances reproducibility. The platform allows users to set up benchmarks with custom tasks and enables contributions in the form of dataset, code, and meta-data submissions. We cover the following materials design categories: Artificial Intelligence (AI), Electronic Structure (ES), Force-fields (FF), Quantum Computation (QC) and Experiments (EXP). For AI, we cover several types of input data, including atomic structures, atomistic images, spectra, and text. For ES, we consider multiple ES approaches, software packages, pseudopotentials, materials, and properties, comparing results to experiment. For FF, we compare multiple approaches for material property predictions. For QC, we benchmark Hamiltonian simulations using various quantum algorithms and circuits. Finally, for experiments, we use the inter-laboratory approach to establish benchmarks. There are 1281 contributions to 274 benchmarks using 152 methods with more than 8 million data-points, and the leaderboard is continuously expanding. The JARVIS-Leaderboard is available at the website: https://pages.nist.gov/jarvis_leaderboard

We identify seven new 192-periodic infinite families of elements in the 2-primary stable homotopy groups of spheres. Although their Hurewicz image is trivial for topological modular forms, they remain nontrivial after T(2)- as well as K(2)-localization. We also obtain new information about 2-torsion and 2-divisibility of some of the previously known 192-periodic infinite families in the stable stems.

We present a self-supervised, time-to-event (TTE) foundation model called MOTOR (Many Outcome Time Oriented Representations) which is pretrained on timestamped sequences of events in electronic health records (EHR) and health insurance claims. TTE models are used for estimating the probability distribution of the time until a specific event occurs, which is an important task in medical settings. TTE models provide many advantages over classification using fixed time horizons, including naturally handling censored observations, but are challenging to train with limited labeled data. MOTOR addresses this challenge by pretraining on up to 55M patient records (9B clinical events). We evaluate MOTOR's transfer learning performance on 19 tasks, across 3 patient databases (a private EHR system, MIMIC-IV, and Merative claims data). Task-specific models adapted from MOTOR improve time-dependent C statistics by 4.6% over state-of-the-art, improve label efficiency by up to 95% ,and are more robust to temporal distributional shifts. We further evaluate cross-site portability by adapting our MOTOR foundation model for six prediction tasks on the MIMIC-IV dataset, where it outperforms all baselines. MOTOR is the first foundation model for medical TTE predictions and we release a 143M parameter pretrained model for research use at [redacted URL].

Previous works on Treatment Effect Estimation (TEE) are not in widespread use because they are predominantly theoretical, where strong parametric assumptions are made but untractable for practical application. Recent work uses multilayer perceptron (MLP) for modeling casual relationships, however, MLPs lag far behind recent advances in ML methodology, which limits their applicability and generalizability. To extend beyond the single domain formulation and towards more realistic learning scenarios, we explore model design spaces beyond MLPs, i.e., transformer backbones, which provide flexibility where attention layers govern interactions among treatments and covariates to exploit structural similarities of potential outcomes for confounding control. Through careful model design, Transformers as Treatment Effect Estimators (TransTEE) is proposed. We show empirically that TransTEE can: (1) serve as a general purpose treatment effect estimator that significantly outperforms competitive baselines in a variety of challenging TEE problems (e.g., discrete, continuous, structured, or dosage-associated treatments) and is applicable to both when covariates are tabular and when they consist of structural data (e.g., texts, graphs); (2) yield multiple advantages: compatibility with propensity score modeling, parameter efficiency, robustness to continuous treatment value distribution shifts, explainable in covariate adjustment, and real-world utility in auditing pre-trained language models

The search for a general model that can operate seamlessly across multiple domains remains a key goal in machine learning research. The prevailing methodology in Reinforcement Learning (RL) typically limits models to a single task within a unimodal framework, a limitation that contrasts with the broader vision of a versatile, multi-domain model. In this paper, we present Jack of All Trades (JAT), a transformer-based model with a unique design optimized for handling sequential decision-making tasks and multimodal data types. The JAT model demonstrates its robust capabilities and versatility by achieving strong performance on very different RL benchmarks, along with promising results on Computer Vision (CV) and Natural Language Processing (NLP) tasks, all using a single set of weights. The JAT model marks a significant step towards more general, cross-domain AI model design, and notably, it is the first model of its kind to be fully open-sourced (see https://huggingface.co/jat-project/jat), including a pioneering general-purpose dataset.

This report introduces a new family of multimodal models, Gemini, that exhibit remarkable capabilities across image, audio, video, and text understanding. The Gemini family consists of Ultra, Pro, and Nano sizes, suitable for applications ranging from complex reasoning tasks to on-device memory-constrained use-cases. Evaluation on a broad range of benchmarks shows that our most-capable Gemini Ultra model advances the state of the art in 30 of 32 of these benchmarks - notably being the first model to achieve human-expert performance on the well-studied exam benchmark MMLU, and improving the state of the art in every one of the 20 multimodal benchmarks we examined. We believe that the new capabilities of Gemini models in cross-modal reasoning and language understanding will enable a wide variety of use cases and we discuss our approach toward deploying them responsibly to users.

The paper presents the performance results of Reactor Mk.1, ARCs flagship large language model, through a benchmarking process analysis. The model utilizes the Lychee AI engine and possesses less than 100 billion parameters, resulting in a combination of efficiency and potency. The Reactor Mk.1 outperformed models such as GPT-4o, Claude Opus, and Llama 3, with achieved scores of 92% on the MMLU dataset, 91% on HumanEval dataset, and 88% on BBH dataset. It excels in both managing difficult jobs and reasoning, establishing as a prominent AI solution in the present cutting-edge AI technology.

The one-dimensional J_1-J_2 q-state Potts model is solved exactly for arbitrary q, based on using OpenAI's latest reasoning model o3-mini-high to exactly solve the q=3 case. The exact results provide insights to outstanding physical problems such as the stacking of atomic or electronic orders in layered materials and the formation of a T_c-dome-shaped phase often seen in unconventional superconductors. The work is anticipated to fuel both the research in one-dimensional frustrated magnets for recently discovered finite-temperature application potentials and the fast moving topic area of AI for sciences.

This article motivates, describes, and presents the PBSCR dataset for studying composer recognition of classical piano music. Our goal was to design a dataset that facilitates large-scale research on composer recognition that is suitable for modern architectures and training practices. To achieve this goal, we utilize the abundance of sheet music images and rich metadata on IMSLP, use a previously proposed feature representation called a bootleg score to encode the location of noteheads relative to staff lines, and present the data in an extremely simple format (2D binary images) to encourage rapid exploration and iteration. The dataset itself contains 40,000 62x64 bootleg score images for a 9-class recognition task, 100,000 62x64 bootleg score images for a 100-class recognition task, and 29,310 unlabeled variable-length bootleg score images for pretraining. The labeled data is presented in a form that mirrors MNIST images, in order to make it extremely easy to visualize, manipulate, and train models in an efficient manner. We include relevant information to connect each bootleg score image with its underlying raw sheet music image, and we scrape, organize, and compile metadata from IMSLP on all piano works to facilitate multimodal research and allow for convenient linking to other datasets. We release baseline results in a supervised and low-shot setting for future works to compare against, and we discuss open research questions that the PBSCR data is especially well suited to facilitate research on.

The progress of AI is bottlenecked by the quality of evaluation, and powerful LLM-as-a-Judge models have proved to be a core solution. Improved judgment ability is enabled by stronger chain-of-thought reasoning, motivating the need to find the best recipes for training such models to think. In this work we introduce J1, a reinforcement learning approach to training such models. Our method converts both verifiable and non-verifiable prompts to judgment tasks with verifiable rewards that incentivize thinking and mitigate judgment bias. In particular, our approach outperforms all other existing 8B or 70B models when trained at those sizes, including models distilled from DeepSeek-R1. J1 also outperforms o1-mini, and even R1 on some benchmarks, despite training a smaller model. We provide analysis and ablations comparing Pairwise-J1 vs Pointwise-J1 models, offline vs online training recipes, reward strategies, seed prompts, and variations in thought length and content. We find that our models make better judgments by learning to outline evaluation criteria, comparing against self-generated reference answers, and re-evaluating the correctness of model responses.

Modeling the joint distribution of data samples and their properties allows to construct a single model for both data generation and property prediction, with synergistic benefits reaching beyond purely generative or predictive models. However, training joint models presents daunting architectural and optimization challenges. Here, we propose Hyformer, a transformer-based joint model that successfully blends the generative and predictive functionalities, using an alternating attention mechanism and a joint pre-training scheme. We show that Hyformer is simultaneously optimized for molecule generation and property prediction, while exhibiting synergistic benefits in conditional sampling, out-of-distribution property prediction and representation learning. Finally, we demonstrate the benefits of joint learning in a drug design use case of discovering novel antimicrobial~peptides.

The unsupervised task of Joint Alignment (JA) of images is beset by challenges such as high complexity, geometric distortions, and convergence to poor local or even global optima. Although Vision Transformers (ViT) have recently provided valuable features for JA, they fall short of fully addressing these issues. Consequently, researchers frequently depend on expensive models and numerous regularization terms, resulting in long training times and challenging hyperparameter tuning. We introduce the Spatial Joint Alignment Model (SpaceJAM), a novel approach that addresses the JA task with efficiency and simplicity. SpaceJAM leverages a compact architecture with only 16K trainable parameters and uniquely operates without the need for regularization or atlas maintenance. Evaluations on SPair-71K and CUB datasets demonstrate that SpaceJAM matches the alignment capabilities of existing methods while significantly reducing computational demands and achieving at least a 10x speedup. SpaceJAM sets a new standard for rapid and effective image alignment, making the process more accessible and efficient. Our code is available at: https://bgu-cs-vil.github.io/SpaceJAM/.

Training models with varying capacities can be advantageous for deploying them in different scenarios. While high-capacity models offer better performance, low-capacity models require fewer computing resources for training and inference. In this work, we propose a novel one-stop training framework to jointly train high-capacity and low-capactiy models. This framework consists of two composite model architectures and a joint training algorithm called Two-Stage Joint-Training (TSJT). Unlike knowledge distillation, where multiple capacity models are trained from scratch separately, our approach integrates supervisions from different capacity models simultaneously, leading to faster and more efficient convergence. Extensive experiments on the multilingual machine translation benchmark WMT10 show that our method outperforms low-capacity baseline models and achieves comparable or better performance on high-capacity models. Notably, the analysis demonstrates that our method significantly influences the initial training process, leading to more efficient convergence and superior solutions.

Temporal Point Processes (TPP) are probabilistic generative frameworks. They model discrete event sequences localized in continuous time. Generally, real-life events reveal descriptive information, known as marks. Marked TPPs model time and marks of the event together for practical relevance. Conditioned on past events, marked TPPs aim to learn the joint distribution of the time and the mark of the next event. For simplicity, conditionally independent TPP models assume time and marks are independent given event history. They factorize the conditional joint distribution of time and mark into the product of individual conditional distributions. This structural limitation in the design of TPP models hurt the predictive performance on entangled time and mark interactions. In this work, we model the conditional inter-dependence of time and mark to overcome the limitations of conditionally independent models. We construct a multivariate TPP conditioning the time distribution on the current event mark in addition to past events. Besides the conventional intensity-based models for conditional joint distribution, we also draw on flexible intensity-free TPP models from the literature. The proposed TPP models outperform conditionally independent and dependent models in standard prediction tasks. Our experimentation on various datasets with multiple evaluation metrics highlights the merit of the proposed approach.

Representation learning methods have revolutionized machine learning on networks by converting discrete network structures into continuous domains. However, dynamic networks that evolve over time pose new challenges. To address this, dynamic representation learning methods have gained attention, offering benefits like reduced learning time and improved accuracy by utilizing temporal information. T-batching is a valuable technique for training dynamic network models that reduces training time while preserving vital conditions for accurate modeling. However, we have identified a limitation in the training loss function used with t-batching. Through mathematical analysis, we propose two alternative loss functions that overcome these issues, resulting in enhanced training performance. We extensively evaluate the proposed loss functions on synthetic and real-world dynamic networks. The results consistently demonstrate superior performance compared to the original loss function. Notably, in a real-world network characterized by diverse user interaction histories, the proposed loss functions achieved more than 26.9% enhancement in Mean Reciprocal Rank (MRR) and more than 11.8% improvement in Recall@10. These findings underscore the efficacy of the proposed loss functions in dynamic network modeling.

We study sampling algorithms for β-ensembles with time complexity less than cubic in the cardinality of the ensemble. Following Dumitriu & Edelman (2002), we see the ensemble as the eigenvalues of a random tridiagonal matrix, namely a random Jacobi matrix. First, we provide a unifying and elementary treatment of the tridiagonal models associated to the three classical Hermite, Laguerre and Jacobi ensembles. For this purpose, we use simple changes of variables between successive reparametrizations of the coefficients defining the tridiagonal matrix. Second, we derive an approximate sampler for the simulation of β-ensembles, and illustrate how fast it can be for polynomial potentials. This method combines a Gibbs sampler on Jacobi matrices and the diagonalization of these matrices. In practice, even for large ensembles, only a few Gibbs passes suffice for the marginal distribution of the eigenvalues to fit the expected theoretical distribution. When the conditionals in the Gibbs sampler can be simulated exactly, the same fast empirical convergence is observed for the fluctuations of the largest eigenvalue. Our experimental results support a conjecture by Krishnapur et al. (2016), that the Gibbs chain on Jacobi matrices of size N mixes in O(log(N)).

Self-supervised learning has seen great success recently in unsupervised representation learning, enabling breakthroughs in natural language and image processing. However, these methods often rely on autoregressive and masked modeling, which aim to reproduce masked information in the input, which can be vulnerable to the presence of noise or confounding variables. To address this problem, Joint-Embedding Predictive Architectures (JEPA) has been introduced with the aim to perform self-supervised learning in the latent space. To leverage these advancements in the domain of time series, we introduce Time Series JEPA (TS-JEPA), an architecture specifically adapted for time series representation learning. We validate TS-JEPA on both classification and forecasting, showing that it can match or surpass current state-of-the-art baselines on different standard datasets. Notably, our approach demonstrates a strong performance balance across diverse tasks, indicating its potential as a robust foundation for learning general representations. Thus, this work lays the groundwork for developing future time series foundation models based on Joint Embedding.

De novo drug design requires simultaneously generating novel molecules outside of training data and predicting their target properties, making it a hard task for generative models. To address this, we propose Joint Transformer that combines a Transformer decoder, Transformer encoder, and a predictor in a joint generative model with shared weights. We formulate a probabilistic black-box optimization algorithm that employs Joint Transformer to generate novel molecules with improved target properties and outperforms other SMILES-based optimization methods in de novo drug design.

Markov jump processes are continuous-time stochastic processes which describe dynamical systems evolving in discrete state spaces. These processes find wide application in the natural sciences and machine learning, but their inference is known to be far from trivial. In this work we introduce a methodology for zero-shot inference of Markov jump processes (MJPs), on bounded state spaces, from noisy and sparse observations, which consists of two components. First, a broad probability distribution over families of MJPs, as well as over possible observation times and noise mechanisms, with which we simulate a synthetic dataset of hidden MJPs and their noisy observation process. Second, a neural network model that processes subsets of the simulated observations, and that is trained to output the initial condition and rate matrix of the target MJP in a supervised way. We empirically demonstrate that one and the same (pretrained) model can infer, in a zero-shot fashion, hidden MJPs evolving in state spaces of different dimensionalities. Specifically, we infer MJPs which describe (i) discrete flashing ratchet systems, which are a type of Brownian motors, and the conformational dynamics in (ii) molecular simulations, (iii) experimental ion channel data and (iv) simple protein folding models. What is more, we show that our model performs on par with state-of-the-art models which are finetuned to the target datasets.

We study in detail a one-dimensional lattice model of a continuum, conserved field (mass) that is transferred deterministically between neighbouring random sites. The model falls in a wider class of lattice models capturing the joint effect of random advection and diffusion and encompassing as specific cases, some models studied in the literature, like the Kang-Redner, Kipnis-Marchioro-Presutti, Takayasu-Taguchi, etc. The motivation for our setup comes from a straightforward interpretation as advection of particles in one-dimensional turbulence, but it is also related to a problem of synchronization of dynamical systems driven by common noise. For finite lattices, we study both the coalescence of an initially spread field (interpreted as roughening), and the statistical steady-state properties. We distinguish two main size-dependent regimes, depending on the strength of the diffusion term and on the lattice size. Using numerical simulations and mean-field approach, we study the statistics of the field. For weak diffusion, we unveil a characteristic hierarchical structure of the field. We also connect the model and the iterated function systems concept.