Daily Papers

Large Multimodal Models (LMMs) have achieved remarkable progress across various capabilities; however, complex video reasoning in the scientific domain remains a significant and challenging frontier. Current video benchmarks predominantly target general scenarios where perception/recognition is heavily relied on, while with relatively simple reasoning tasks, leading to saturation and thus failing to effectively evaluate advanced multimodal cognitive skills. To address this critical gap, we introduce SciVideoBench, a rigorous benchmark specifically designed to assess advanced video reasoning in scientific contexts. SciVideoBench consists of 1,000 carefully crafted multiple-choice questions derived from cutting-edge scientific experimental videos spanning over 25 specialized academic subjects and verified by a semi-automatic system. Each question demands sophisticated domain-specific knowledge, precise spatiotemporal perception, and intricate logical reasoning, effectively challenging models' higher-order cognitive abilities. Our evaluation highlights significant performance deficits in state-of-the-art proprietary and open-source LMMs, including Gemini 2.5 Pro and Qwen2.5-VL, indicating substantial room for advancement in video reasoning capabilities. Detailed analyses of critical factors such as reasoning complexity and visual grounding provide valuable insights and clear direction for future developments in LMMs, driving the evolution of truly capable multimodal AI co-scientists. We hope SciVideoBench could fit the interests of the community and help to push the boundary of cutting-edge AI for border science.

Building a working mental model of a protein typically requires weeks of reading, cross-referencing crystal and predicted structures, and inspecting ligand complexes, an effort that is slow, unevenly accessible, and often requires specialized computational skills. We introduce Speak to a Protein, a new capability that turns protein analysis into an interactive, multimodal dialogue with an expert co-scientist. The AI system retrieves and synthesizes relevant literature, structures, and ligand data; grounds answers in a live 3D scene; and can highlight, annotate, manipulate and see the visualization. It also generates and runs code when needed, explaining results in both text and graphics. We demonstrate these capabilities on relevant proteins, posing questions about binding pockets, conformational changes, or structure-activity relationships to test ideas in real-time. Speak to a Protein reduces the time from question to evidence, lowers the barrier to advanced structural analysis, and enables hypothesis generation by tightly coupling language, code, and 3D structures. Speak to a Protein is freely accessible at https://open.playmolecule.org.

The rapid development of Artificial Intelligence (AI) has revolutionized numerous fields, with large language models (LLMs) and computer vision (CV) systems driving advancements in natural language understanding and visual processing, respectively. The convergence of these technologies has catalyzed the rise of multimodal AI, enabling richer, cross-modal understanding that spans text, vision, audio, and video modalities. Multimodal large language models (MLLMs), in particular, have emerged as a powerful framework, demonstrating impressive capabilities in tasks like image-text generation, visual question answering, and cross-modal retrieval. Despite these advancements, the complexity and scale of MLLMs introduce significant challenges in interpretability and explainability, essential for establishing transparency, trustworthiness, and reliability in high-stakes applications. This paper provides a comprehensive survey on the interpretability and explainability of MLLMs, proposing a novel framework that categorizes existing research across three perspectives: (I) Data, (II) Model, (III) Training \& Inference. We systematically analyze interpretability from token-level to embedding-level representations, assess approaches related to both architecture analysis and design, and explore training and inference strategies that enhance transparency. By comparing various methodologies, we identify their strengths and limitations and propose future research directions to address unresolved challenges in multimodal explainability. This survey offers a foundational resource for advancing interpretability and transparency in MLLMs, guiding researchers and practitioners toward developing more accountable and robust multimodal AI systems.

Multimodal scientific problems (MSPs) involve complex issues that require the integration of multiple modalities, such as text and diagrams, presenting a significant challenge in artificial intelligence. While progress has been made in addressing traditional scientific problems, MSPs still face two primary issues: the challenge of multi-modal comprehensive reasoning in scientific problem-solving and the lack of reflective and rethinking capabilities. To address these issues, we introduce a Multi-Agent framework based on the Big Seven Personality and Socratic guidance (MAPS). This framework employs seven distinct agents that leverage feedback mechanisms and the Socratic method to guide the resolution of MSPs. To tackle the first issue, we propose a progressive four-agent solving strategy, where each agent focuses on a specific stage of the problem-solving process. For the second issue, we introduce a Critic agent, inspired by Socratic questioning, which prompts critical thinking and stimulates autonomous learning. We conduct extensive experiments on the EMMA, Olympiad, and MathVista datasets, achieving promising results that outperform the current SOTA model by 15.84% across all tasks. Meanwhile, the additional analytical experiments also verify the model's progress as well as generalization ability.

In the rapidly evolving landscape of AI research and application, Multimodal Large Language Models (MLLMs) have emerged as a transformative force, adept at interpreting and integrating information from diverse modalities such as text, images, and Graphical User Interfaces (GUIs). Despite these advancements, the nuanced interaction and understanding of GUIs pose a significant challenge, limiting the potential of existing models to enhance automation levels. To bridge this gap, this paper presents V-Zen, an innovative Multimodal Large Language Model (MLLM) meticulously crafted to revolutionise the domain of GUI understanding and grounding. Equipped with dual-resolution image encoders, V-Zen establishes new benchmarks in efficient grounding and next-action prediction, thereby laying the groundwork for self-operating computer systems. Complementing V-Zen is the GUIDE dataset, an extensive collection of real-world GUI elements and task-based sequences, serving as a catalyst for specialised fine-tuning. The successful integration of V-Zen and GUIDE marks the dawn of a new era in multimodal AI research, opening the door to intelligent, autonomous computing experiences. This paper extends an invitation to the research community to join this exciting journey, shaping the future of GUI automation. In the spirit of open science, our code, data, and model will be made publicly available, paving the way for multimodal dialogue scenarios with intricate and precise interactions.

Recent advancements in artificial intelligence have sparked interest in scientific assistants that could support researchers across the full spectrum of scientific workflows, from literature review to experimental design and data analysis. A key capability for such systems is the ability to process and reason about scientific information in both visual and textual forms - from interpreting spectroscopic data to understanding laboratory setups. Here, we introduce MaCBench, a comprehensive benchmark for evaluating how vision-language models handle real-world chemistry and materials science tasks across three core aspects: data extraction, experimental understanding, and results interpretation. Through a systematic evaluation of leading models, we find that while these systems show promising capabilities in basic perception tasks - achieving near-perfect performance in equipment identification and standardized data extraction - they exhibit fundamental limitations in spatial reasoning, cross-modal information synthesis, and multi-step logical inference. Our insights have important implications beyond chemistry and materials science, suggesting that developing reliable multimodal AI scientific assistants may require advances in curating suitable training data and approaches to training those models.

Scientific user facilities, such as synchrotron beamlines, are equipped with a wide array of hardware and software tools that require a codebase for human-computer-interaction. This often necessitates developers to be involved to establish connection between users/researchers and the complex instrumentation. The advent of generative AI presents an opportunity to bridge this knowledge gap, enabling seamless communication and efficient experimental workflows. Here we present a modular architecture for the Virtual Scientific Companion (VISION) by assembling multiple AI-enabled cognitive blocks that each scaffolds large language models (LLMs) for a specialized task. With VISION, we performed LLM-based operation on the beamline workstation with low latency and demonstrated the first voice-controlled experiment at an X-ray scattering beamline. The modular and scalable architecture allows for easy adaptation to new instrument and capabilities. Development on natural language-based scientific experimentation is a building block for an impending future where a science exocortex -- a synthetic extension to the cognition of scientists -- may radically transform scientific practice and discovery.

Scientific reasoning, the process through which humans apply logic, evidence, and critical thinking to explore and interpret scientific phenomena, is essential in advancing knowledge reasoning across diverse fields. However, despite significant progress, current scientific reasoning models still struggle with generalization across domains and often fall short of multimodal perception. Multimodal Large Language Models (MLLMs), which integrate text, images, and other modalities, present an exciting opportunity to overcome these limitations and enhance scientific reasoning. Therefore, this position paper argues that MLLMs can significantly advance scientific reasoning across disciplines such as mathematics, physics, chemistry, and biology. First, we propose a four-stage research roadmap of scientific reasoning capabilities, and highlight the current state of MLLM applications in scientific reasoning, noting their ability to integrate and reason over diverse data types. Second, we summarize the key challenges that remain obstacles to achieving MLLM's full potential. To address these challenges, we propose actionable insights and suggestions for the future. Overall, our work offers a novel perspective on MLLM integration with scientific reasoning, providing the LLM community with a valuable vision for achieving Artificial General Intelligence (AGI).

Scientific discovery is a complex cognitive process that has driven human knowledge and technological progress for centuries. While artificial intelligence (AI) has made significant advances in automating aspects of scientific reasoning, simulation, and experimentation, we still lack integrated AI systems capable of performing autonomous long-term scientific research and discovery. This paper examines the current state of AI for scientific discovery, highlighting recent progress in large language models and other AI techniques applied to scientific tasks. We then outline key challenges and promising research directions toward developing more comprehensive AI systems for scientific discovery, including the need for science-focused AI agents, improved benchmarks and evaluation metrics, multimodal scientific representations, and unified frameworks combining reasoning, theorem proving, and data-driven modeling. Addressing these challenges could lead to transformative AI tools to accelerate progress across disciplines towards scientific discovery.

A multimodal AI agent is characterized by its ability to process and learn from various types of data, including natural language, visual, and audio inputs, to inform its actions. Despite advancements in large language models that incorporate visual data, such as GPT-4V, effectively translating image-based data into actionable outcomes for AI agents continues to be challenging. In this paper, we introduce a multimodal model that incorporates the concept of functional token specifically designed for AI agent applications. To ensure compatibility with edge devices, our model is optimized to a compact size of less than 1B parameters. Like GPT-4, our model can process both English and Chinese. We demonstrate that this model is capable of operating efficiently on a wide range of edge devices, including as constrained as a Raspberry Pi.

Scientific discoveries increasingly rely on complex multimodal reasoning based on information-intensive scientific data and domain-specific expertise. Empowered by expert-level scientific benchmarks, scientific Multimodal Large Language Models (MLLMs) hold the potential to significantly enhance this discovery process in realistic workflows. However, current scientific benchmarks mostly focus on evaluating the knowledge understanding capabilities of MLLMs, leading to an inadequate assessment of their perception and reasoning abilities. To address this gap, we present the Scientists' First Exam (SFE) benchmark, designed to evaluate the scientific cognitive capacities of MLLMs through three interconnected levels: scientific signal perception, scientific attribute understanding, scientific comparative reasoning. Specifically, SFE comprises 830 expert-verified VQA pairs across three question types, spanning 66 multimodal tasks across five high-value disciplines. Extensive experiments reveal that current state-of-the-art GPT-o3 and InternVL-3 achieve only 34.08% and 26.52% on SFE, highlighting significant room for MLLMs to improve in scientific realms. We hope the insights obtained in SFE will facilitate further developments in AI-enhanced scientific discoveries.

Multimodal learning, a rapidly evolving field in artificial intelligence, seeks to construct more versatile and robust systems by integrating and analyzing diverse types of data, including text, images, audio, and video. Inspired by the human ability to assimilate information through many senses, this method enables applications such as text-to-video conversion, visual question answering, and image captioning. Recent developments in datasets that support multimodal language models (MLLMs) are highlighted in this overview. Large-scale multimodal datasets are essential because they allow for thorough testing and training of these models. With an emphasis on their contributions to the discipline, the study examines a variety of datasets, including those for training, domain-specific tasks, and real-world applications. It also emphasizes how crucial benchmark datasets are for assessing models' performance in a range of scenarios, scalability, and applicability. Since multimodal learning is always changing, overcoming these obstacles will help AI research and applications reach new heights.

Multimodal learning has revolutionized general domain tasks, yet its application in scientific discovery is hindered by the profound semantic gap between complex scientific imagery and sparse textual descriptions. We present S1-MMAlign, a large-scale, multi-disciplinary multimodal dataset comprising over 15.5 million high-quality image-text pairs derived from 2.5 million open-access scientific papers. Spanning disciplines from physics and biology to engineering, the dataset captures diverse visual modalities including experimental setups, heatmaps, and microscopic imagery. To address the pervasive issue of weak alignment in raw scientific captions, we introduce an AI-ready semantic enhancement pipeline that utilizes the Qwen-VL multimodal large model series to recaption images by synthesizing context from paper abstracts and citation contexts. Technical validation demonstrates that this enhancement significantly improves data quality: SciBERT-based pseudo-perplexity metrics show reduced semantic ambiguity, while CLIP scores indicate an 18.21% improvement in image-text alignment. S1-MMAlign provides a foundational resource for advancing scientific reasoning and cross-modal understanding in the era of AI for Science. The dataset is publicly available at https://huggingface.co/datasets/ScienceOne-AI/S1-MMAlign.

Large Language Models (LLMs) are playing an expanding role in physics research by enhancing reasoning, symbolic manipulation, and numerical computation. However, ensuring the reliability and interpretability of their outputs remains a significant challenge. In our framework, we conceptualize the collaboration between AI and human scientists as a dynamic interplay among three modules: the reasoning module, the interpretation module, and the AI-scientist interaction module. Recognizing that effective physics reasoning demands rigorous logical consistency, quantitative precision, and deep integration with established theoretical models, we introduce the interpretation module to improve the understanding of AI-generated outputs, which is not previously explored in the literature. This module comprises multiple specialized agents, including summarizers, model builders, UI builders, and testers, which collaboratively structure LLM outputs within a physically grounded framework, by constructing a more interpretable science model. A case study demonstrates that our approach enhances transparency, facilitates validation, and strengthens AI-augmented reasoning in scientific discovery.

This comprehensive survey explored the evolving landscape of generative Artificial Intelligence (AI), with a specific focus on the transformative impacts of Mixture of Experts (MoE), multimodal learning, and the speculated advancements towards Artificial General Intelligence (AGI). It critically examined the current state and future trajectory of generative Artificial Intelligence (AI), exploring how innovations like Google's Gemini and the anticipated OpenAI Q* project are reshaping research priorities and applications across various domains, including an impact analysis on the generative AI research taxonomy. It assessed the computational challenges, scalability, and real-world implications of these technologies while highlighting their potential in driving significant progress in fields like healthcare, finance, and education. It also addressed the emerging academic challenges posed by the proliferation of both AI-themed and AI-generated preprints, examining their impact on the peer-review process and scholarly communication. The study highlighted the importance of incorporating ethical and human-centric methods in AI development, ensuring alignment with societal norms and welfare, and outlined a strategy for future AI research that focuses on a balanced and conscientious use of MoE, multimodality, and AGI in generative AI.

AI is increasingly playing a pivotal role in transforming how scientific discoveries are made. We introduce The AI Scientist-v2, an end-to-end agentic system capable of producing the first entirely AI generated peer-review-accepted workshop paper. This system iteratively formulates scientific hypotheses, designs and executes experiments, analyzes and visualizes data, and autonomously authors scientific manuscripts. Compared to its predecessor (v1, Lu et al., 2024 arXiv:2408.06292), The AI Scientist-v2 eliminates the reliance on human-authored code templates, generalizes effectively across diverse machine learning domains, and leverages a novel progressive agentic tree-search methodology managed by a dedicated experiment manager agent. Additionally, we enhance the AI reviewer component by integrating a Vision-Language Model (VLM) feedback loop for iterative refinement of content and aesthetics of the figures. We evaluated The AI Scientist-v2 by submitting three fully autonomous manuscripts to a peer-reviewed ICLR workshop. Notably, one manuscript achieved high enough scores to exceed the average human acceptance threshold, marking the first instance of a fully AI-generated paper successfully navigating a peer review. This accomplishment highlights the growing capability of AI in conducting all aspects of scientific research. We anticipate that further advancements in autonomous scientific discovery technologies will profoundly impact human knowledge generation, enabling unprecedented scalability in research productivity and significantly accelerating scientific breakthroughs, greatly benefiting society at large. We have open-sourced the code at https://github.com/SakanaAI/AI-Scientist-v2 to foster the future development of this transformative technology. We also discuss the role of AI in science, including AI safety.

In recent years, large language models (LLMs) have driven major advances in language understanding, marking a significant step toward artificial general intelligence (AGI). With increasing demands for higher-level semantics and cross-modal fusion, multimodal large language models (MLLMs) have emerged, integrating diverse information sources (e.g., text, vision, and audio) to enhance modeling and reasoning in complex scenarios. In AI for Science, multimodal emotion recognition and reasoning has become a rapidly growing frontier. While LLMs and MLLMs have achieved notable progress in this area, the field still lacks a systematic review that consolidates recent developments. To address this gap, this paper provides a comprehensive survey of LLMs and MLLMs for emotion recognition and reasoning, covering model architectures, datasets, and performance benchmarks. We further highlight key challenges and outline future research directions, aiming to offer researchers both an authoritative reference and practical insights for advancing this domain. To the best of our knowledge, this paper is the first attempt to comprehensively survey the intersection of MLLMs with multimodal emotion recognition and reasoning. The summary of existing methods mentioned is in our Github: https://github.com/yuntaoshou/Awesome-Emotion-Reasoning{https://github.com/yuntaoshou/Awesome-Emotion-Reasoning}.

With the rapid development of Large Language Models (LLMs), AI agents have demonstrated increasing proficiency in scientific tasks, ranging from hypothesis generation and experimental design to manuscript writing. Such agent systems are commonly referred to as "AI Scientists." However, existing AI Scientists predominantly formulate scientific discovery as a standalone search or optimization problem, overlooking the fact that scientific research is inherently a social and collaborative endeavor. Real-world science relies on a complex scientific infrastructure composed of collaborative mechanisms, contribution attribution, peer review, and structured scientific knowledge networks. Due to the lack of modeling for these critical dimensions, current systems struggle to establish a genuine research ecosystem or interact deeply with the human scientific community. To bridge this gap, we introduce OmniScientist, a framework that explicitly encodes the underlying mechanisms of human research into the AI scientific workflow. OmniScientist not only achieves end-to-end automation across data foundation, literature review, research ideation, experiment automation, scientific writing, and peer review, but also provides comprehensive infrastructural support by simulating the human scientific system, comprising: (1) a structured knowledge system built upon citation networks and conceptual correlations; (2) a collaborative research protocol (OSP), which enables seamless multi-agent collaboration and human researcher participation; and (3) an open evaluation platform (ScienceArena) based on blind pairwise user voting and Elo rankings. This infrastructure empowers agents to not only comprehend and leverage human knowledge systems but also to collaborate and co-evolve, fostering a sustainable and scalable innovation ecosystem.

The rapid advancement of scientific progress requires innovative tools that can accelerate discovery. While recent AI methods, particularly large language models (LLMs), have shown promise in tasks such as hypothesis generation and experimental design, they fall short in replicating the collaborative nature of real-world scientific practices, where diverse teams of experts work together to tackle complex problems. To address the limitation, we propose an LLM-based multi-agent system, i.e., Virtual Scientists (VirSci), designed to mimic the teamwork inherent in scientific research. VirSci organizes a team of agents to collaboratively generate, evaluate, and refine research ideas. Through comprehensive experiments, we demonstrate that this multi-agent approach outperforms the state-of-the-art method in producing novel and impactful scientific ideas, showing potential in aligning with key insights in the Science of Science field. Our findings suggest that integrating collaborative agents can lead to more innovative scientific outputs, offering a robust system for autonomous scientific discovery.

Multimodal research is an emerging field of artificial intelligence, and one of the main research problems in this field is multimodal fusion. The fusion of multimodal data is the process of integrating multiple unimodal representations into one compact multimodal representation. Previous research in this field has exploited the expressiveness of tensors for multimodal representation. However, these methods often suffer from exponential increase in dimensions and in computational complexity introduced by transformation of input into tensor. In this paper, we propose the Low-rank Multimodal Fusion method, which performs multimodal fusion using low-rank tensors to improve efficiency. We evaluate our model on three different tasks: multimodal sentiment analysis, speaker trait analysis, and emotion recognition. Our model achieves competitive results on all these tasks while drastically reducing computational complexity. Additional experiments also show that our model can perform robustly for a wide range of low-rank settings, and is indeed much more efficient in both training and inference compared to other methods that utilize tensor representations.

Multi-modal AI systems will likely become a ubiquitous presence in our everyday lives. A promising approach to making these systems more interactive is to embody them as agents within physical and virtual environments. At present, systems leverage existing foundation models as the basic building blocks for the creation of embodied agents. Embedding agents within such environments facilitates the ability of models to process and interpret visual and contextual data, which is critical for the creation of more sophisticated and context-aware AI systems. For example, a system that can perceive user actions, human behavior, environmental objects, audio expressions, and the collective sentiment of a scene can be used to inform and direct agent responses within the given environment. To accelerate research on agent-based multimodal intelligence, we define "Agent AI" as a class of interactive systems that can perceive visual stimuli, language inputs, and other environmentally-grounded data, and can produce meaningful embodied action with infinite agent. In particular, we explore systems that aim to improve agents based on next-embodied action prediction by incorporating external knowledge, multi-sensory inputs, and human feedback. We argue that by developing agentic AI systems in grounded environments, one can also mitigate the hallucinations of large foundation models and their tendency to generate environmentally incorrect outputs. The emerging field of Agent AI subsumes the broader embodied and agentic aspects of multimodal interactions. Beyond agents acting and interacting in the physical world, we envision a future where people can easily create any virtual reality or simulated scene and interact with agents embodied within the virtual environment.

Recent advances in large language models (LLMs) have fueled the vision of automated scientific discovery, often called AI Co-Scientists. To date, prior work casts these systems as generative co-authors responsible for crafting hypotheses, synthesizing code, or drafting manuscripts. In this work, we explore a complementary application: using LLMs as verifiers to automate the academic verification of scientific manuscripts. To that end, we introduce SPOT, a dataset of 83 published papers paired with 91 errors significant enough to prompt errata or retraction, cross-validated with actual authors and human annotators. Evaluating state-of-the-art LLMs on SPOT, we find that none surpasses 21.1\% recall or 6.1\% precision (o3 achieves the best scores, with all others near zero). Furthermore, confidence estimates are uniformly low, and across eight independent runs, models rarely rediscover the same errors, undermining their reliability. Finally, qualitative analysis with domain experts reveals that even the strongest models make mistakes resembling student-level misconceptions derived from misunderstandings. These findings highlight the substantial gap between current LLM capabilities and the requirements for dependable AI-assisted academic verification.

Our experience of the world is multimodal - we see objects, hear sounds, feel texture, smell odors, and taste flavors. Modality refers to the way in which something happens or is experienced and a research problem is characterized as multimodal when it includes multiple such modalities. In order for Artificial Intelligence to make progress in understanding the world around us, it needs to be able to interpret such multimodal signals together. Multimodal machine learning aims to build models that can process and relate information from multiple modalities. It is a vibrant multi-disciplinary field of increasing importance and with extraordinary potential. Instead of focusing on specific multimodal applications, this paper surveys the recent advances in multimodal machine learning itself and presents them in a common taxonomy. We go beyond the typical early and late fusion categorization and identify broader challenges that are faced by multimodal machine learning, namely: representation, translation, alignment, fusion, and co-learning. This new taxonomy will enable researchers to better understand the state of the field and identify directions for future research.

AI co-scientists are emerging as a tool to assist human researchers in achieving their research goals. A crucial feature of these AI co-scientists is the ability to generate a research plan given a set of aims and constraints. The plan may be used by researchers for brainstorming, or may even be implemented after further refinement. However, language models currently struggle to generate research plans that follow all constraints and implicit requirements. In this work, we study how to leverage the vast corpus of existing research papers to train language models that generate better research plans. We build a scalable, diverse training corpus by automatically extracting research goals and goal-specific grading rubrics from papers across several domains. We then train models for research plan generation via reinforcement learning with self-grading. A frozen copy of the initial policy acts as the grader during training, with the rubrics creating a generator-verifier gap that enables improvements without external human supervision. To validate this approach, we conduct a study with human experts for machine learning research goals, spanning 225 hours. The experts prefer plans generated by our finetuned Qwen3-30B-A3B model over the initial model for 70% of research goals, and approve 84% of the automatically extracted goal-specific grading rubrics. To assess generality, we also extend our approach to research goals from medical papers, and new arXiv preprints, evaluating with a jury of frontier models. Our finetuning yields 12-22% relative improvements and significant cross-domain generalization, proving effective even in problem settings like medical research where execution feedback is infeasible. Together, these findings demonstrate the potential of a scalable, automated training recipe as a step towards improving general AI co-scientists.

As information exists in various modalities in real world, effective interaction and fusion among multimodal information plays a key role for the creation and perception of multimodal data in computer vision and deep learning research. With superb power in modeling the interaction among multimodal information, multimodal image synthesis and editing has become a hot research topic in recent years. Instead of providing explicit guidance for network training, multimodal guidance offers intuitive and flexible means for image synthesis and editing. On the other hand, this field is also facing several challenges in alignment of multimodal features, synthesis of high-resolution images, faithful evaluation metrics, etc. In this survey, we comprehensively contextualize the advance of the recent multimodal image synthesis and editing and formulate taxonomies according to data modalities and model types. We start with an introduction to different guidance modalities in image synthesis and editing, and then describe multimodal image synthesis and editing approaches extensively according to their model types. After that, we describe benchmark datasets and evaluation metrics as well as corresponding experimental results. Finally, we provide insights about the current research challenges and possible directions for future research. A project associated with this survey is available at https://github.com/fnzhan/Generative-AI.

While conversational generative AI has shown considerable potential in enhancing decision-making for agricultural professionals, its exploration has predominantly been anchored in text-based interactions. The evolution of multimodal conversational AI, leveraging vast amounts of image-text data from diverse sources, marks a significant stride forward. However, the application of such advanced vision-language models in the agricultural domain, particularly for crop disease diagnosis, remains underexplored. In this work, we present the crop disease domain multimodal (CDDM) dataset, a pioneering resource designed to advance the field of agricultural research through the application of multimodal learning techniques. The dataset comprises 137,000 images of various crop diseases, accompanied by 1 million question-answer pairs that span a broad spectrum of agricultural knowledge, from disease identification to management practices. By integrating visual and textual data, CDDM facilitates the development of sophisticated question-answering systems capable of providing precise, useful advice to farmers and agricultural professionals. We demonstrate the utility of the dataset by finetuning state-of-the-art multimodal models, showcasing significant improvements in crop disease diagnosis. Specifically, we employed a novel finetuning strategy that utilizes low-rank adaptation (LoRA) to finetune the visual encoder, adapter and language model simultaneously. Our contributions include not only the dataset but also a finetuning strategy and a benchmark to stimulate further research in agricultural technology, aiming to bridge the gap between advanced AI techniques and practical agricultural applications. The dataset is available at https: //github.com/UnicomAI/UnicomBenchmark/tree/main/CDDMBench.

This survey and application guide to multimodal large language models(MLLMs) explores the rapidly developing field of MLLMs, examining their architectures, applications, and impact on AI and Generative Models. Starting with foundational concepts, we delve into how MLLMs integrate various data types, including text, images, video and audio, to enable complex AI systems for cross-modal understanding and generation. It covers essential topics such as training methods, architectural components, and practical applications in various fields, from visual storytelling to enhanced accessibility. Through detailed case studies and technical analysis, the text examines prominent MLLM implementations while addressing key challenges in scalability, robustness, and cross-modal learning. Concluding with a discussion of ethical considerations, responsible AI development, and future directions, this authoritative resource provides both theoretical frameworks and practical insights. It offers a balanced perspective on the opportunities and challenges in the development and deployment of MLLMs, and is highly valuable for researchers, practitioners, and students interested in the intersection of natural language processing and computer vision.

Large Language Models (LLMs) struggle with hallucinations and outdated knowledge due to their reliance on static training data. Retrieval-Augmented Generation (RAG) mitigates these issues by integrating external dynamic information enhancing factual and updated grounding. Recent advances in multimodal learning have led to the development of Multimodal RAG, incorporating multiple modalities such as text, images, audio, and video to enhance the generated outputs. However, cross-modal alignment and reasoning introduce unique challenges to Multimodal RAG, distinguishing it from traditional unimodal RAG. This survey offers a structured and comprehensive analysis of Multimodal RAG systems, covering datasets, metrics, benchmarks, evaluation, methodologies, and innovations in retrieval, fusion, augmentation, and generation. We precisely review training strategies, robustness enhancements, and loss functions, while also exploring the diverse Multimodal RAG scenarios. Furthermore, we discuss open challenges and future research directions to support advancements in this evolving field. This survey lays the foundation for developing more capable and reliable AI systems that effectively leverage multimodal dynamic external knowledge bases. Resources are available at https://github.com/llm-lab-org/Multimodal-RAG-Survey.

Recent advancements in Multimodal Large Language Models (MLLMs) underscore the significance of scalable models and data to boost performance, yet this often incurs substantial computational costs. Although the Mixture of Experts (MoE) architecture has been employed to efficiently scale large language and image-text models, these efforts typically involve fewer experts and limited modalities. To address this, our work presents the pioneering attempt to develop a unified MLLM with the MoE architecture, named Uni-MoE that can handle a wide array of modalities. Specifically, it features modality-specific encoders with connectors for a unified multimodal representation. We also implement a sparse MoE architecture within the LLMs to enable efficient training and inference through modality-level data parallelism and expert-level model parallelism. To enhance the multi-expert collaboration and generalization, we present a progressive training strategy: 1) Cross-modality alignment using various connectors with different cross-modality data, 2) Training modality-specific experts with cross-modality instruction data to activate experts' preferences, and 3) Tuning the Uni-MoE framework utilizing Low-Rank Adaptation (LoRA) on mixed multimodal instruction data. We evaluate the instruction-tuned Uni-MoE on a comprehensive set of multimodal datasets. The extensive experimental results demonstrate Uni-MoE's principal advantage of significantly reducing performance bias in handling mixed multimodal datasets, alongside improved multi-expert collaboration and generalization. Our findings highlight the substantial potential of MoE frameworks in advancing MLLMs and the code is available at https://github.com/HITsz-TMG/UMOE-Scaling-Unified-Multimodal-LLMs.

Large Multimodal Models (LMMs) have ushered in a new era in artificial intelligence, merging capabilities in both language and vision to form highly capable Visual Foundation Agents. These agents are postulated to excel across a myriad of tasks, potentially approaching general artificial intelligence. However, existing benchmarks fail to sufficiently challenge or showcase the full potential of LMMs in complex, real-world environments. To address this gap, we introduce VisualAgentBench (VAB), a comprehensive and pioneering benchmark specifically designed to train and evaluate LMMs as visual foundation agents across diverse scenarios, including Embodied, Graphical User Interface, and Visual Design, with tasks formulated to probe the depth of LMMs' understanding and interaction capabilities. Through rigorous testing across nine proprietary LMM APIs and eight open models, we demonstrate the considerable yet still developing agent capabilities of these models. Additionally, VAB constructs a trajectory training set constructed through hybrid methods including Program-based Solvers, LMM Agent Bootstrapping, and Human Demonstrations, promoting substantial performance improvements in LMMs through behavior cloning. Our work not only aims to benchmark existing models but also provides a solid foundation for future development into visual foundation agents. Code, train \& test data, and part of fine-tuned open LMMs are available at https://github.com/THUDM/VisualAgentBench.

Automating the generation of scientific videos is a crucial yet challenging task for effective knowledge dissemination. However, existing works on document automation primarily focus on static media such as posters and slides, lacking mechanisms for personalized dynamic orchestration and multimodal content synchronization. To address these challenges, we introduce VideoAgent, a novel multi-agent framework that synthesizes personalized scientific videos through a conversational interface. VideoAgent parses a source paper into a fine-grained asset library and, guided by user requirements, orchestrates a narrative flow that synthesizes both static slides and dynamic animations to explain complex concepts. To enable rigorous evaluation, we also propose SciVidEval, the first comprehensive suite for this task, which combines automated metrics for multimodal content quality and synchronization with a Video-Quiz-based human evaluation to measure knowledge transfer. Extensive experiments demonstrate that our method significantly outperforms existing commercial scientific video generation services and approaches human-level quality in scientific communication.

Artificial General Intelligence (AGI) requires comprehensive understanding and generation capabilities for a variety of tasks spanning different modalities and functionalities. Integrative AI is one important direction to approach AGI, through combining multiple models to tackle complex multimodal tasks. However, there is a lack of a flexible and composable platform to facilitate efficient and effective model composition and coordination. In this paper, we propose the i-Code Studio, a configurable and composable framework for Integrative AI. The i-Code Studio orchestrates multiple pre-trained models in a finetuning-free fashion to conduct complex multimodal tasks. Instead of simple model composition, the i-Code Studio provides an integrative, flexible, and composable setting for developers to quickly and easily compose cutting-edge services and technologies tailored to their specific requirements. The i-Code Studio achieves impressive results on a variety of zero-shot multimodal tasks, such as video-to-text retrieval, speech-to-speech translation, and visual question answering. We also demonstrate how to quickly build a multimodal agent based on the i-Code Studio that can communicate and personalize for users.

Large Multimodal Models (LMMs) are increasingly applied to scientific research, yet it remains unclear whether they can reliably understand and reason over the multimodal complexity of papers. A central challenge lies in detecting and resolving inconsistencies across text, figures, tables, and equations, issues that are often subtle, domain-specific, and ultimately undermine clarity, reproducibility, and trust. Existing benchmarks overlook this issue, either isolating single modalities or relying on synthetic errors that fail to capture real-world complexity. We introduce PRISMM-Bench (Peer-Review-sourced Inconsistency Set for Multimodal Models), the first benchmark grounded in real reviewer-flagged inconsistencies in scientific papers. Through a multi-stage pipeline of review mining, LLM-assisted filtering and human verification, we curate 262 inconsistencies from 242 papers. Based on this set, we design three tasks, namely inconsistency identification, remedy and pair matching, which assess a model's capacity to detect, correct, and reason over inconsistencies across different modalities. Furthermore, to address the notorious problem of choice-only shortcuts in multiple-choice evaluation, where models exploit answer patterns without truly understanding the question, we further introduce structured JSON-based answer representations that minimize linguistic biases by reducing reliance on superficial stylistic cues. We benchmark 21 leading LMMs, including large open-weight models (GLM-4.5V 106B, InternVL3 78B) and proprietary models (Gemini 2.5 Pro, GPT-5 with high reasoning). Results reveal strikingly low performance (26.1-54.2%), underscoring the challenge of multimodal scientific reasoning and motivating progress towards trustworthy scientific assistants.

Recent advancements in multimodal large language models (MLLMs) and video agent systems have significantly improved general video understanding. However, when applied to scientific video understanding and educating, a domain that demands external professional knowledge integration and rigorous step-wise reasoning, existing approaches often struggle. To bridge this gap, we propose SciEducator, the first iterative self-evolving multi-agent system for scientific video comprehension and education. Rooted in the classical Deming Cycle from management science, our design reformulates its Plan-Do-Study-Act philosophy into a self-evolving reasoning and feedback mechanism, which facilitates the interpretation of intricate scientific activities in videos. Moreover, SciEducator can produce multimodal educational content tailored to specific scientific processes, including textual instructions, visual guides, audio narrations, and interactive references. To support evaluation, we construct SciVBench, a benchmark consisting of 500 expert-verified and literature-grounded science QA pairs across five categories, covering physical, chemical, and everyday phenomena. Extensive experiments demonstrate that SciEducator substantially outperforms leading closed-source MLLMs (e.g., Gemini, GPT-4o) and state-of-the-art video agents on the benchmark, establishing a new paradigm for the community.

Connecting text and visual modalities plays an essential role in generative intelligence. For this reason, inspired by the success of large language models, significant research efforts are being devoted to the development of Multimodal Large Language Models (MLLMs). These models can seamlessly integrate visual and textual modalities, both as input and output, while providing a dialogue-based interface and instruction-following capabilities. In this paper, we provide a comprehensive review of recent visual-based MLLMs, analyzing their architectural choices, multimodal alignment strategies, and training techniques. We also conduct a detailed analysis of these models across a wide range of tasks, including visual grounding, image generation and editing, visual understanding, and domain-specific applications. Additionally, we compile and describe training datasets and evaluation benchmarks, conducting comparisons among existing models in terms of performance and computational requirements. Overall, this survey offers a comprehensive overview of the current state of the art, laying the groundwork for future MLLMs.

Visualizations play a crucial part in effective communication of concepts and information. Recent advances in reasoning and retrieval augmented generation have enabled Large Language Models (LLMs) to perform deep research and generate comprehensive reports. Despite its progress, existing deep research frameworks primarily focus on generating text-only content, leaving the automated generation of interleaved texts and visualizations underexplored. This novel task poses key challenges in designing informative visualizations and effectively integrating them with text reports. To address these challenges, we propose Formal Description of Visualization (FDV), a structured textual representation of charts that enables LLMs to learn from and generate diverse, high-quality visualizations. Building on this representation, we introduce Multimodal DeepResearcher, an agentic framework that decomposes the task into four stages: (1) researching, (2) exemplar report textualization, (3) planning, and (4) multimodal report generation. For the evaluation of generated multimodal reports, we develop MultimodalReportBench, which contains 100 diverse topics served as inputs along with 5 dedicated metrics. Extensive experiments across models and evaluation methods demonstrate the effectiveness of Multimodal DeepResearcher. Notably, utilizing the same Claude 3.7 Sonnet model, Multimodal DeepResearcher achieves an 82\% overall win rate over the baseline method.

Multimodal reasoning, which integrates language and visual cues into problem solving and decision making, is a fundamental aspect of human intelligence and a crucial step toward artificial general intelligence. However, the evaluation of multimodal reasoning capabilities in Multimodal Large Language Models (MLLMs) remains inadequate. Most existing reasoning benchmarks are constrained by limited data size, narrow domain coverage, and unstructured knowledge distribution. To close these gaps, we introduce MDK12-Bench, a multi-disciplinary benchmark assessing the reasoning capabilities of MLLMs via real-world K-12 examinations. Spanning six disciplines (math, physics, chemistry, biology, geography, and information science), our benchmark comprises 140K reasoning instances across diverse difficulty levels from primary school to 12th grade. It features 6,827 instance-level knowledge point annotations based on a well-organized knowledge structure, detailed answer explanations, difficulty labels and cross-year partitions, providing a robust platform for comprehensive evaluation. Additionally, we present a novel dynamic evaluation framework to mitigate data contamination issues by bootstrapping question forms, question types, and image styles during evaluation. Extensive experiment on MDK12-Bench reveals the significant limitation of current MLLMs in multimodal reasoning. The findings on our benchmark provide insights into the development of the next-generation models. Our data and codes are available at https://github.com/LanceZPF/MDK12.

A big convergence of language, multimodal perception, action, and world modeling is a key step toward artificial general intelligence. In this work, we introduce Kosmos-1, a Multimodal Large Language Model (MLLM) that can perceive general modalities, learn in context (i.e., few-shot), and follow instructions (i.e., zero-shot). Specifically, we train Kosmos-1 from scratch on web-scale multimodal corpora, including arbitrarily interleaved text and images, image-caption pairs, and text data. We evaluate various settings, including zero-shot, few-shot, and multimodal chain-of-thought prompting, on a wide range of tasks without any gradient updates or finetuning. Experimental results show that Kosmos-1 achieves impressive performance on (i) language understanding, generation, and even OCR-free NLP (directly fed with document images), (ii) perception-language tasks, including multimodal dialogue, image captioning, visual question answering, and (iii) vision tasks, such as image recognition with descriptions (specifying classification via text instructions). We also show that MLLMs can benefit from cross-modal transfer, i.e., transfer knowledge from language to multimodal, and from multimodal to language. In addition, we introduce a dataset of Raven IQ test, which diagnoses the nonverbal reasoning capability of MLLMs.

With the advent of large multimodal language models, science is now at a threshold of an AI-based technological transformation. Recently, a plethora of new AI models and tools has been proposed, promising to empower researchers and academics worldwide to conduct their research more effectively and efficiently. This includes all aspects of the research cycle, especially (1) searching for relevant literature; (2) generating research ideas and conducting experimentation; generating (3) text-based and (4) multimodal content (e.g., scientific figures and diagrams); and (5) AI-based automatic peer review. In this survey, we provide an in-depth overview over these exciting recent developments, which promise to fundamentally alter the scientific research process for good. Our survey covers the five aspects outlined above, indicating relevant datasets, methods and results (including evaluation) as well as limitations and scope for future research. Ethical concerns regarding shortcomings of these tools and potential for misuse (fake science, plagiarism, harms to research integrity) take a particularly prominent place in our discussion. We hope that our survey will not only become a reference guide for newcomers to the field but also a catalyst for new AI-based initiatives in the area of "AI4Science".

Different Multimodal Large Language Models (MLLMs) cannot be integrated into a unified multimodal input-output system directly. In previous work, training has been considered as an inevitable component due to challenges in modal alignment, Text-to-Speech efficiency and other integration issues. In this paper, we introduce Multimodal Large Language Model Orchestration, an effective approach for creating interactive multimodal AI systems without additional training. MLLM Orchestration leverages the inherent reasoning capabilities of large language models to coordinate specialized models through explicit workflows, enabling natural multimodal interactions while maintaining modularity, improving interpretability, and significantly enhancing computational efficiency. Our orchestration framework is built upon three key innovations: (1) a central controller LLM that analyzes user inputs and dynamically routes tasks to appropriate specialized models through carefully designed agents; (2) a parallel Text-to-Speech architecture that enables true full-duplex interaction with seamless interruption handling and natural conversational flow; and (3) a cross-modal memory integration system that maintains coherent context across modalities through intelligent information synthesis and retrieval, selectively avoiding unnecessary modality calls in certain scenarios to improve response speed. Extensive evaluations demonstrate that MLLM Orchestration achieves comprehensive multimodal capabilities without additional training, performance improvements of up to 7.8% over traditional jointly-trained approaches on standard benchmarks, reduced latency by 10.3%, and significantly enhanced interpretability through explicit orchestration processes.

Publishing open-source academic video recordings is an emergent and prevalent approach to sharing knowledge online. Such videos carry rich multimodal information including speech, the facial and body movements of the speakers, as well as the texts and pictures in the slides and possibly even the papers. Although multiple academic video datasets have been constructed and released, few of them support both multimodal content recognition and understanding tasks, which is partially due to the lack of high-quality human annotations. In this paper, we propose a novel multimodal, multigenre, and multipurpose audio-visual academic lecture dataset (M^3AV), which has almost 367 hours of videos from five sources covering computer science, mathematics, and medical and biology topics. With high-quality human annotations of the spoken and written words, in particular high-valued name entities, the dataset can be used for multiple audio-visual recognition and understanding tasks. Evaluations performed on contextual speech recognition, speech synthesis, and slide and script generation tasks demonstrate that the diversity of M^3AV makes it a challenging dataset.

Lecture slide presentations, a sequence of pages that contain text and figures accompanied by speech, are constructed and presented carefully in order to optimally transfer knowledge to students. Previous studies in multimedia and psychology attribute the effectiveness of lecture presentations to their multimodal nature. As a step toward developing AI to aid in student learning as intelligent teacher assistants, we introduce the Multimodal Lecture Presentations dataset as a large-scale benchmark testing the capabilities of machine learning models in multimodal understanding of educational content. Our dataset contains aligned slides and spoken language, for 180+ hours of video and 9000+ slides, with 10 lecturers from various subjects (e.g., computer science, dentistry, biology). We introduce two research tasks which are designed as stepping stones towards AI agents that can explain (automatically captioning a lecture presentation) and illustrate (synthesizing visual figures to accompany spoken explanations) educational content. We provide manual annotations to help implement these two research tasks and evaluate state-of-the-art models on them. Comparing baselines and human student performances, we find that current models struggle in (1) weak crossmodal alignment between slides and spoken text, (2) learning novel visual mediums, (3) technical language, and (4) long-range sequences. Towards addressing this issue, we also introduce PolyViLT, a multimodal transformer trained with a multi-instance learning loss that is more effective than current approaches. We conclude by shedding light on the challenges and opportunities in multimodal understanding of educational presentations.

We present Cephalo, a series of multimodal vision large language models (V-LLMs) designed for materials science applications, integrating visual and linguistic data for enhanced understanding and interaction within human-AI and multi-agent AI frameworks. A key innovation of Cephalo is its advanced dataset generation method, which employs a sophisticated algorithm to accurately detect and separate images and their corresponding textual descriptions from PDF documents, such as scientific papers. The method includes a careful refinement of image-text pairs through integrated vision and language processing, ensuring high-quality, contextually relevant, and well reasoned training data. Cephalo is trained on integrated image and text data extracted from thousands of scientific papers and science-focused Wikipedia pages demonstrates can interpret complex visual scenes, generate precise language descriptions, and answer queries about images effectively. The combination of a vision encoder with an autoregressive transformer supports complex natural language understanding in an integrated model, which can be coupled with other generative methods to create an image-to-text-to-image or image-to-text-to-3D pipeline. To explore the development of larger models from smaller ones, we merge sets of layers that originate from different pre-trained source models. This hybrid approach allows us to leverage the domain-specific expertise and general conversational capabilities to harness the strengths of multiple models. We examine the models in diverse use cases that incorporate biological materials, fracture and engineering analysis, protein biophysics, and bio-inspired design based on insect behavior. Generative applications include bio-inspired designs, including pollen-inspired architected materials, as well as the synthesis of bio-inspired material microstructures from a photograph of a solar eclipse.

Modern Artificial Intelligence (AI) increasingly relies on multi-agent architectures that blend visual and language understanding. Yet, a pressing challenge remains: How can we trust these agents especially in zero-shot settings with no fine-tuning? We introduce a novel modular Agentic AI visual classification framework that integrates generalist multimodal agents with a non-visual reasoning orchestrator and a Retrieval-Augmented Generation (RAG) module. Applied to apple leaf disease diagnosis, we benchmark three configurations: (I) zero-shot with confidence-based orchestration, (II) fine-tuned agents with improved performance, and (III) trust-calibrated orchestration enhanced by CLIP-based image retrieval and re-evaluation loops. Using confidence calibration metrics (ECE, OCR, CCC), the orchestrator modulates trust across agents. Our results demonstrate a 77.94\% accuracy improvement in the zero-shot setting using trust-aware orchestration and RAG, achieving 85.63\% overall. GPT-4o showed better calibration, while Qwen-2.5-VL displayed overconfidence. Furthermore, image-RAG grounded predictions with visually similar cases, enabling correction of agent overconfidence via iterative re-evaluation. The proposed system separates perception (vision agents) from meta-reasoning (orchestrator), enabling scalable and interpretable multi-agent AI. This blueprint is extensible to diagnostics, biology, and other trust-critical domains. All models, prompts, results, and system components including the complete software source code are openly released to support reproducibility, transparency, and community benchmarking at Github: https://github.com/Applied-AI-Research-Lab/Orchestrator-Agent-Trust

The rapid advancement of Large Language Models (LLMs) and Large Multimodal Models (LMMs) has heightened the demand for AI-based scientific assistants capable of understanding scientific articles and figures. Despite progress, there remains a significant gap in evaluating models' comprehension of professional, graduate-level, and even PhD-level scientific content. Current datasets and benchmarks primarily focus on relatively simple scientific tasks and figures, lacking comprehensive assessments across diverse advanced scientific disciplines. To bridge this gap, we collected a multimodal, multidisciplinary dataset from open-access scientific articles published in Nature Communications journals. This dataset spans 72 scientific disciplines, ensuring both diversity and quality. We created benchmarks with various tasks and settings to comprehensively evaluate LMMs' capabilities in understanding scientific figures and content. Our evaluation revealed that these tasks are highly challenging: many open-source models struggled significantly, and even GPT-4V and GPT-4o faced difficulties. We also explored using our dataset as training resources by constructing visual instruction-following data, enabling the 7B LLaVA model to achieve performance comparable to GPT-4V/o on our benchmark. Additionally, we investigated the use of our interleaved article texts and figure images for pre-training LMMs, resulting in improvements on the material generation task. The source dataset, including articles, figures, constructed benchmarks, and visual instruction-following data, is open-sourced.

As chatbots continue to evolve toward human-like, real-world, interactions, multimodality remains an active area of research and exploration. So far, efforts to integrate multimodality into chatbots have primarily focused on image-centric tasks, such as visual dialogue and image-based instructions, placing emphasis on the "eyes" of human perception while neglecting the "ears", namely auditory aspects. Moreover, these studies often center around static interactions that focus on discussing the modality rather than naturally incorporating it into the conversation, which limits the richness of simultaneous, dynamic engagement. Furthermore, while multimodality has been explored in multi-party and multi-session conversations, task-specific constraints have hindered its seamless integration into dynamic, natural conversations. To address these challenges, this study aims to equip chatbots with "eyes and ears" capable of more immersive interactions with humans. As part of this effort, we introduce a new multimodal conversation dataset, Multimodal Multi-Session Multi-Party Conversation (M^3C), and propose a novel multimodal conversation model featuring multimodal memory retrieval. Our model, trained on the M^3C, demonstrates the ability to seamlessly engage in long-term conversations with multiple speakers in complex, real-world-like settings, effectively processing visual and auditory inputs to understand and respond appropriately. Human evaluations highlight the model's strong performance in maintaining coherent and dynamic interactions, demonstrating its potential for advanced multimodal conversational agents.

Scientific research demands sophisticated reasoning over multimodal data, a challenge especially prevalent in biology. Despite recent advances in multimodal large language models (MLLMs) for AI-assisted research, existing multimodal reasoning benchmarks only target up to college-level difficulty, while research-level benchmarks emphasize lower-level perception, falling short of the complex multimodal reasoning needed for scientific discovery. To bridge this gap, we introduce MicroVQA, a visual-question answering (VQA) benchmark designed to assess three reasoning capabilities vital in research workflows: expert image understanding, hypothesis generation, and experiment proposal. MicroVQA consists of 1,042 multiple-choice questions (MCQs) curated by biology experts across diverse microscopy modalities, ensuring VQA samples represent real scientific practice. In constructing the benchmark, we find that standard MCQ generation methods induce language shortcuts, motivating a new two-stage pipeline: an optimized LLM prompt structures question-answer pairs into MCQs; then, an agent-based `RefineBot' updates them to remove shortcuts. Benchmarking on state-of-the-art MLLMs reveal a peak performance of 53\%; models with smaller LLMs only slightly underperform top models, suggesting that language-based reasoning is less challenging than multimodal reasoning; and tuning with scientific articles enhances performance. Expert analysis of chain-of-thought responses shows that perception errors are the most frequent, followed by knowledge errors and then overgeneralization errors. These insights highlight the challenges in multimodal scientific reasoning, showing MicroVQA is a valuable resource advancing AI-driven biomedical research. MicroVQA is available at https://huggingface.co/datasets/jmhb/microvqa, and project page at https://jmhb0.github.io/microvqa.

Large Language Models (LLMs) have demonstrated remarkable capabilities in challenging, knowledge-intensive reasoning tasks. However, extending LLMs to perceive and reason over a new modality (e.g., vision), often requires costly development of large-scale vision language models (VLMs) with LLMs as backbones. Smaller VLMs are more efficient and adaptable but often lack the broad knowledge and reasoning capabilities of frontier LLMs. In this work, we propose BeMyEyes, a modular, multi-agent framework for extending LLMs to multimodal reasoning by orchestrating collaboration between efficient, adaptable VLMs as perceivers and powerful LLMs as reasoners through conversations. We then introduce a data synthesis and supervised fine-tuning pipeline to train the perceiver agent to effectively collaborate with the reasoner agent. By combining the complementary strengths of perception and reasoning agents, BeMyEyes avoids the need for training large-scale multimodal models, preserves the generalization and reasoning capabilities of LLMs, and allows flexible extension to new domains and modalities. Experiments show that our framework unlocks the multimodal reasoning capabilities for LLMs, enabling a lightweight and fully open-source solution, i.e. equipping text-only DeepSeek-R1 with Qwen2.5-VL-7B perceiver, to outperform large-scale proprietary VLMs such as GPT-4o on a wide range of knowledge-intensive multimodal tasks. These results demonstrate the effectiveness, modularity, and scalability of our multi-agent approach for building future multimodal reasoning systems.

Artificial intelligence (AI) is reshaping scientific discovery, evolving from specialized computational tools into autonomous research partners. We position Agentic Science as a pivotal stage within the broader AI for Science paradigm, where AI systems progress from partial assistance to full scientific agency. Enabled by large language models (LLMs), multimodal systems, and integrated research platforms, agentic AI shows capabilities in hypothesis generation, experimental design, execution, analysis, and iterative refinement -- behaviors once regarded as uniquely human. This survey provides a domain-oriented review of autonomous scientific discovery across life sciences, chemistry, materials science, and physics. We unify three previously fragmented perspectives -- process-oriented, autonomy-oriented, and mechanism-oriented -- through a comprehensive framework that connects foundational capabilities, core processes, and domain-specific realizations. Building on this framework, we (i) trace the evolution of AI for Science, (ii) identify five core capabilities underpinning scientific agency, (iii) model discovery as a dynamic four-stage workflow, (iv) review applications across the above domains, and (v) synthesize key challenges and future opportunities. This work establishes a domain-oriented synthesis of autonomous scientific discovery and positions Agentic Science as a structured paradigm for advancing AI-driven research.

Recently, there is an increasing interest in using artificial intelligence (AI) to automate aspects of the research process, or even autonomously conduct the full research cycle from idea generation, over data analysis, to composing and evaluation of scientific manuscripts. Examples of working AI scientist systems have been demonstrated for computer science tasks and running molecular biology labs. While some approaches aim for full autonomy of the scientific AI, others rather aim for leveraging human-AI teaming. Here, we address how to adapt such approaches for boosting Brain-Computer Interface (BCI) development, as well as brain research resp. neuroscience at large. We argue that at this time, a strong emphasis on human-AI teaming, in contrast to fully autonomous AI BCI researcher will be the most promising way forward. We introduce the collaborative workspaces concept for human-AI teaming based on a set of Janusian design principles, looking both ways, to the human as well as to the AI side. Based on these principles, we present ChatBCI, a Python-based toolbox for enabling human-AI collaboration based on interaction with Large Language Models (LLMs), designed for BCI research and development projects. We show how ChatBCI was successfully used in a concrete BCI project on advancing motor imagery decoding from EEG signals. Our approach can be straightforwardly extended to broad neurotechnological and neuroscientific topics, and may by design facilitate human expert knowledge transfer to scientific AI systems in general.

Predicting multiple real-world tasks in a single model often requires a particularly diverse feature space. Multimodal (MM) models aim to extract the synergistic predictive potential of multiple data types to create a shared feature space with aligned semantic meaning across inputs of drastically varying sizes (i.e. images, text, sound). Most current MM architectures fuse these representations in parallel, which not only limits their interpretability but also creates a dependency on modality availability. We present MultiModN, a multimodal, modular network that fuses latent representations in a sequence of any number, combination, or type of modality while providing granular real-time predictive feedback on any number or combination of predictive tasks. MultiModN's composable pipeline is interpretable-by-design, as well as innately multi-task and robust to the fundamental issue of biased missingness. We perform four experiments on several benchmark MM datasets across 10 real-world tasks (predicting medical diagnoses, academic performance, and weather), and show that MultiModN's sequential MM fusion does not compromise performance compared with a baseline of parallel fusion. By simulating the challenging bias of missing not-at-random (MNAR), this work shows that, contrary to MultiModN, parallel fusion baselines erroneously learn MNAR and suffer catastrophic failure when faced with different patterns of MNAR at inference. To the best of our knowledge, this is the first inherently MNAR-resistant approach to MM modeling. In conclusion, MultiModN provides granular insights, robustness, and flexibility without compromising performance.

As multimodal large models (MLLMs) continue to advance across challenging tasks, a key question emerges: What essential capabilities are still missing? A critical aspect of human learning is continuous interaction with the environment -- not limited to language, but also involving multimodal understanding and generation. To move closer to human-level intelligence, models must similarly support multi-turn, multimodal interaction. In particular, they should comprehend interleaved multimodal contexts and respond coherently in ongoing exchanges. In this work, we present an initial exploration through the InterMT -- the first preference dataset for multi-turn multimodal interaction, grounded in real human feedback. In this exploration, we particularly emphasize the importance of human oversight, introducing expert annotations to guide the process, motivated by the fact that current MLLMs lack such complex interactive capabilities. InterMT captures human preferences at both global and local levels into nine sub-dimensions, consists of 15.6k prompts, 52.6k multi-turn dialogue instances, and 32.4k human-labeled preference pairs. To compensate for the lack of capability for multi-modal understanding and generation, we introduce an agentic workflow that leverages tool-augmented MLLMs to construct multi-turn QA instances. To further this goal, we introduce InterMT-Bench to assess the ability of MLLMs in assisting judges with multi-turn, multimodal tasks. We demonstrate the utility of \InterMT through applications such as judge moderation and further reveal the multi-turn scaling law of judge model. We hope the open-source of our data can help facilitate further research on aligning current MLLMs to the next step. Our project website can be found at https://pku-intermt.github.io .

While recently Multimodal Large Language Models (MM-LLMs) have made exciting strides, they mostly fall prey to the limitation of only input-side multimodal understanding, without the ability to produce content in multiple modalities. As we humans always perceive the world and communicate with people through various modalities, developing any-to-any MM-LLMs capable of accepting and delivering content in any modality becomes essential to human-level AI. To fill the gap, we present an end-to-end general-purpose any-to-any MM-LLM system, NExT-GPT. We connect an LLM with multimodal adaptors and different diffusion decoders, enabling NExT-GPT to perceive inputs and generate outputs in arbitrary combinations of text, images, videos, and audio. By leveraging the existing well-trained highly-performing encoders and decoders, NExT-GPT is tuned with only a small amount of parameter (1%) of certain projection layers, which not only benefits low-cost training and also facilitates convenient expansion to more potential modalities. Moreover, we introduce a modality-switching instruction tuning (MosIT) and manually curate a high-quality dataset for MosIT, based on which NExT-GPT is empowered with complex cross-modal semantic understanding and content generation. Overall, our research showcases the promising possibility of building an AI agent capable of modeling universal modalities, paving the way for more human-like AI research in the community.

Learning holistic computational representations in physical, chemical or biological systems requires the ability to process information from different distributions and modalities within the same model. Thus, the demand for multimodal machine learning models has sharply risen for modalities that go beyond vision and language, such as sequences, graphs, time series, or tabular data. While there are many available multimodal fusion and alignment approaches, most of them require end-to-end training, scale quadratically with the number of modalities, cannot handle cases of high modality imbalance in the training set, or are highly topology-specific, making them too restrictive for many biomedical learning tasks. This paper presents Multimodal Lego (MM-Lego), a modular and general-purpose fusion and model merging framework to turn any set of encoders into a competitive multimodal model with no or minimal fine-tuning. We achieve this by introducing a wrapper for unimodal encoders that enforces lightweight dimensionality assumptions between modalities and harmonises their representations by learning features in the frequency domain to enable model merging with little signal interference. We show that MM-Lego 1) can be used as a model merging method which achieves competitive performance with end-to-end fusion models without any fine-tuning, 2) can operate on any unimodal encoder, and 3) is a model fusion method that, with minimal fine-tuning, achieves state-of-the-art results on six benchmarked multimodal biomedical tasks.

Scientific discovery relies on scientists generating novel hypotheses that undergo rigorous experimental validation. To augment this process, we introduce an AI co-scientist, a multi-agent system built on Gemini 2.0. The AI co-scientist is intended to help uncover new, original knowledge and to formulate demonstrably novel research hypotheses and proposals, building upon prior evidence and aligned to scientist-provided research objectives and guidance. The system's design incorporates a generate, debate, and evolve approach to hypothesis generation, inspired by the scientific method and accelerated by scaling test-time compute. Key contributions include: (1) a multi-agent architecture with an asynchronous task execution framework for flexible compute scaling; (2) a tournament evolution process for self-improving hypotheses generation. Automated evaluations show continued benefits of test-time compute, improving hypothesis quality. While general purpose, we focus development and validation in three biomedical areas: drug repurposing, novel target discovery, and explaining mechanisms of bacterial evolution and anti-microbial resistance. For drug repurposing, the system proposes candidates with promising validation findings, including candidates for acute myeloid leukemia that show tumor inhibition in vitro at clinically applicable concentrations. For novel target discovery, the AI co-scientist proposed new epigenetic targets for liver fibrosis, validated by anti-fibrotic activity and liver cell regeneration in human hepatic organoids. Finally, the AI co-scientist recapitulated unpublished experimental results via a parallel in silico discovery of a novel gene transfer mechanism in bacterial evolution. These results, detailed in separate, co-timed reports, demonstrate the potential to augment biomedical and scientific discovery and usher an era of AI empowered scientists.

The explainability of a robot's actions is crucial to its acceptance in social spaces. Explaining why a robot fails to complete a given task is particularly important for non-expert users to be aware of the robot's capabilities and limitations. So far, research on explaining robot failures has only considered generating textual explanations, even though several studies have shown the benefits of multimodal ones. However, a simple combination of multiple modalities may lead to semantic incoherence between the information across different modalities - a problem that is not well-studied. An incoherent multimodal explanation can be difficult to understand, and it may even become inconsistent with what the robot and the human observe and how they perform reasoning with the observations. Such inconsistencies may lead to wrong conclusions about the robot's capabilities. In this paper, we introduce an approach to generate coherent multimodal explanations by checking the logical coherence of explanations from different modalities, followed by refinements as required. We propose a classification approach for coherence assessment, where we evaluate if an explanation logically follows another. Our experiments suggest that fine-tuning a neural network that was pre-trained to recognize textual entailment, performs well for coherence assessment of multimodal explanations. Code & data: https://pradippramanick.github.io/coherent-explain/.

As large language models (LLMs) advance, the ultimate vision for their role in science is emerging: we could build an AI collaborator to effectively assist human beings throughout the entire scientific research process. We refer to this envisioned system as ResearchGPT. Given that scientific research progresses through multiple interdependent phases, achieving this vision requires rigorous benchmarks that evaluate the end-to-end workflow rather than isolated sub-tasks. To this end, we contribute CS-54k, a high-quality corpus of scientific Q&A pairs in computer science, built from 14k CC-licensed papers. It is constructed through a scalable, paper-grounded pipeline that combines retrieval-augmented generation (RAG) with multi-stage quality control to ensure factual grounding. From this unified corpus, we derive two complementary subsets: CS-4k, a carefully curated benchmark for evaluating AI's ability to assist scientific research, and CS-50k, a large-scale training dataset. Extensive experiments demonstrate that CS-4k stratifies state-of-the-art LLMs into distinct capability tiers. Open models trained on CS-50k with supervised training and reinforcement learning demonstrate substantial improvements. Even 7B-scale models, when properly trained, outperform many larger proprietary systems, such as GPT-4.1, GPT-4o, and Gemini 2.5 Pro. This indicates that making AI models better research assistants relies more on domain-aligned training with high-quality data than on pretraining scale or general benchmark performance. We release CS-4k and CS-50k in the hope of fostering AI systems as reliable collaborators in CS research.

This paper presents a comprehensive survey of the taxonomy and evolution of multimodal foundation models that demonstrate vision and vision-language capabilities, focusing on the transition from specialist models to general-purpose assistants. The research landscape encompasses five core topics, categorized into two classes. (i) We start with a survey of well-established research areas: multimodal foundation models pre-trained for specific purposes, including two topics -- methods of learning vision backbones for visual understanding and text-to-image generation. (ii) Then, we present recent advances in exploratory, open research areas: multimodal foundation models that aim to play the role of general-purpose assistants, including three topics -- unified vision models inspired by large language models (LLMs), end-to-end training of multimodal LLMs, and chaining multimodal tools with LLMs. The target audiences of the paper are researchers, graduate students, and professionals in computer vision and vision-language multimodal communities who are eager to learn the basics and recent advances in multimodal foundation models.

Advances in AI-assisted research have introduced powerful tools for literature retrieval, hypothesis generation, experimentation, and manuscript preparation. However, systems remain fragmented and lack human-centred workflows. To address these gaps, we introduce AIssistant, an agentic, open-source Human-AI collaborative framework designed to simplify the end-to-end creation of scientific workflows. Since our development is still in an early stage, we present here the first experiments with AIssistant for perspective and review research papers in machine learning. Our system integrates modular tools and agents for literature synthesis, section-wise experimentation, citation management, and automatic LaTeX paper text generation, while maintaining human oversight at every stage to ensure accuracy, coherence, and scholarly rigour. We conducted a comprehensive evaluation across three layers: (1) Independent Human Review, following NeurIPS double-blind standards; (2) Automated LLM Review, using GPT-5 as a scalable human review proxy; and (3) Program Chair Oversight, where the chair monitors the entire review process and makes final validation and acceptance decisions. The results demonstrate that AIssistant improves drafting efficiency and thematic consistency. Nonetheless, Human-AI collaboration remains essential for maintaining factual correctness, methodological soundness, and ethical compliance. Despite its effectiveness, we identify key limitations, including hallucinated citations, difficulty adapting to dynamic paper structures, and incomplete integration of multimodal content.

The recent advancements in generative AI models, which can create realistic and human-like content, are significantly transforming how people communicate, create, and work. While the appropriate use of generative AI models can benefit the society, their misuse poses significant threats to data reliability and authentication. However, due to a lack of aligned multimodal datasets, effective and robust methods for detecting machine-generated content are still in the early stages of development. In this paper, we introduce RU-AI, a new large-scale multimodal dataset designed for the robust and efficient detection of machine-generated content in text, image, and voice. Our dataset is constructed from three large publicly available datasets: Flickr8K, COCO, and Places205, by combining the original datasets and their corresponding machine-generated pairs. Additionally, experimental results show that our proposed unified model, which incorporates a multimodal embedding module with a multilayer perceptron network, can effectively determine the origin of the data (i.e., original data samples or machine-generated ones) from RU-AI. However, future work is still required to address the remaining challenges posed by RU-AI. The source code and dataset are available at https://github.com/ZhihaoZhang97/RU-AI.

The multifaceted nature of human perception and comprehension indicates that, when we think, our body can naturally take any combination of senses, a.k.a., modalities and form a beautiful picture in our brain. For example, when we see a cattery and simultaneously perceive the cat's purring sound, our brain can construct a picture of a cat in the cattery. Intuitively, generative AI models should hold the versatility of humans and be capable of generating images from any combination of modalities efficiently and collaboratively. This paper presents ImgAny, a novel end-to-end multi-modal generative model that can mimic human reasoning and generate high-quality images. Our method serves as the first attempt in its capacity of efficiently and flexibly taking any combination of seven modalities, ranging from language, audio to vision modalities, including image, point cloud, thermal, depth, and event data. Our key idea is inspired by human-level cognitive processes and involves the integration and harmonization of multiple input modalities at both the entity and attribute levels without specific tuning across modalities. Accordingly, our method brings two novel training-free technical branches: 1) Entity Fusion Branch ensures the coherence between inputs and outputs. It extracts entity features from the multi-modal representations powered by our specially constructed entity knowledge graph; 2) Attribute Fusion Branch adeptly preserves and processes the attributes. It efficiently amalgamates distinct attributes from diverse input modalities via our proposed attribute knowledge graph. Lastly, the entity and attribute features are adaptively fused as the conditional inputs to the pre-trained Stable Diffusion model for image generation. Extensive experiments under diverse modality combinations demonstrate its exceptional capability for visual content creation.

Recent advancements in multimodal large language models (MLLMs) have achieved significant multimodal generation capabilities, akin to GPT-4. These models predominantly map visual information into language representation space, leveraging the vast knowledge and powerful text generation abilities of LLMs to produce multimodal instruction-following responses. We could term this method as LLMs for Vision because of its employing LLMs for visual-language understanding, yet observe that these MLLMs neglect the potential of harnessing visual knowledge to enhance overall capabilities of LLMs, which could be regraded as Vision Enhancing LLMs. In this paper, we propose an approach called MKS2, aimed at enhancing LLMs through empowering Multimodal Knowledge Storage and Sharing in LLMs. Specifically, we introduce the Modular Visual Memory, a component integrated into the internal blocks of LLMs, designed to store open-world visual information efficiently. Additionally, we present a soft Mixtures-of-Multimodal Experts architecture in LLMs to invoke multimodal knowledge collaboration during generation. Our comprehensive experiments demonstrate that MKS2 substantially augments the reasoning capabilities of LLMs in contexts necessitating physical or commonsense knowledge. It also delivers competitive results on multimodal benchmarks.

Incorporating visual knowledge into text-only dialogue systems has become a potential direction to imitate the way humans think, imagine, and communicate. However, existing multimodal dialogue systems are either confined by the scale and quality of available datasets or the coarse concept of visual knowledge. To address these issues, we provide a new paradigm of constructing multimodal dialogues as well as two datasets extended from text-only dialogues under such paradigm (ReSee-WoW, ReSee-DD). We propose to explicitly split the visual knowledge into finer granularity (``turn-level'' and ``entity-level''). To further boost the accuracy and diversity of augmented visual information, we retrieve them from the Internet or a large image dataset. To demonstrate the superiority and universality of the provided visual knowledge, we propose a simple but effective framework ReSee to add visual representation into vanilla dialogue models by modality concatenations. We also conduct extensive experiments and ablations w.r.t. different model configurations and visual knowledge settings. Empirical, encouraging results not only demonstrate the effectiveness of introducing visual knowledge at both entity and turn level but also verify the proposed model ReSee outperforms several state-of-the-art methods on automatic and human evaluations. By leveraging text and vision knowledge, ReSee can produce informative responses with real-world visual concepts. Our code is available at https://github.com/ImKeTT/ReSee.

Multi-modal co-learning is emerging as an effective paradigm in machine learning, enabling models to collaboratively learn from different modalities to enhance single-modality predictions. Earth Observation (EO) represents a quintessential domain for multi-modal data analysis, wherein diverse remote sensors collect data to sense our planet. This unprecedented volume of data introduces novel challenges. Specifically, the access to the same sensor modalities at both training and inference stages becomes increasingly complex based on real-world constraints affecting remote sensing platforms. In this context, multi-modal co-learning presents a promising strategy to leverage the vast amount of sensor-derived data available at the training stage to improve single-modality models for inference-time deployment. Most current research efforts focus on designing customized solutions for either particular downstream tasks or specific modalities available at the inference stage. To address this, we propose a novel multi-modal co-learning framework capable of generalizing across various tasks without targeting a specific modality for inference. Our approach combines contrastive and modality discriminative learning together to guide single-modality models to structure the internal model manifold into modality-shared and modality-specific information. We evaluate our framework on four EO benchmarks spanning classification and regression tasks across different sensor modalities, where only one of the modalities available during training is accessible at inference time. Our results demonstrate consistent predictive improvements over state-of-the-art approaches from the recent machine learning and computer vision literature, as well as EO-specific methods. The obtained findings validate our framework in the single-modality inference scenarios across a diverse range of EO applications.

Accessibility remains a critical concern in today's society, as many technologies are not developed to support the full range of user needs. Existing multi-agent systems (MAS) often cannot provide comprehensive assistance for users in need due to the lack of customization stemming from closed-source designs. Consequently, individuals with disabilities frequently encounter significant barriers when attempting to interact with digital environments. We introduce MATE, a multimodal accessibility MAS, which performs the modality conversions based on the user's needs. The system is useful for assisting people with disabilities by ensuring that data will be converted to an understandable format. For instance, if the user cannot see well and receives an image, the system converts this image to its audio description. MATE can be applied to a wide range of domains, industries, and areas, such as healthcare, and can become a useful assistant for various groups of users. The system supports multiple types of models, ranging from LLM API calling to using custom machine learning (ML) classifiers. This flexibility ensures that the system can be adapted to various needs and is compatible with a wide variety of hardware. Since the system is expected to run locally, it ensures the privacy and security of sensitive information. In addition, the framework can be effectively integrated with institutional technologies (e.g., digital healthcare service) for real-time user assistance. Furthermore, we introduce ModCon-Task-Identifier, a model that is capable of extracting the precise modality conversion task from the user input. Numerous experiments show that ModCon-Task-Identifier consistently outperforms other LLMs and statistical models on our custom data. Our code and data are publicly available at https://github.com/AlgazinovAleksandr/Multi-Agent-MATE.

Building general-purpose models that can perceive diverse real-world modalities and solve various tasks is an appealing target in artificial intelligence. In this paper, we present ChatBridge, a novel multimodal language model that leverages the expressive capabilities of language as the catalyst to bridge the gap between various modalities. We show that only language-paired two-modality data is sufficient to connect all modalities. ChatBridge leverages recent large language models (LLM) and extends their zero-shot capabilities to incorporate diverse multimodal inputs. ChatBridge undergoes a two-stage training. The first stage aligns each modality with language, which brings emergent multimodal correlation and collaboration abilities. The second stage instruction-finetunes ChatBridge to align it with user intent with our newly proposed multimodal instruction tuning dataset, named MULTIS, which covers a wide range of 16 multimodal tasks of text, image, video, and audio modalities. We show strong quantitative and qualitative results on zero-shot multimodal tasks covering text, image, video, and audio modalities. All codes, data, and models of ChatBridge will be open-sourced.

Multimodal Large Language Models (MLLMs) are experiencing rapid growth, yielding a plethora of noteworthy contributions in recent months. The prevailing trend involves adopting data-driven methodologies, wherein diverse instruction-following datasets are collected. However, a prevailing challenge persists in these approaches, specifically in relation to the limited visual perception ability, as CLIP-like encoders employed for extracting visual information from inputs. Though these encoders are pre-trained on billions of image-text pairs, they still grapple with the information loss dilemma, given that textual captions only partially capture the contents depicted in images. To address this limitation, this paper proposes to improve the visual perception ability of MLLMs through a mixture-of-experts knowledge enhancement mechanism. Specifically, we introduce a novel method that incorporates multi-task encoders and visual tools into the existing MLLMs training and inference pipeline, aiming to provide a more comprehensive and accurate summarization of visual inputs. Extensive experiments have evaluated its effectiveness of advancing MLLMs, showcasing improved visual perception achieved through the integration of visual experts.

Multimodal AI has the potential to significantly enhance document-understanding tasks, such as processing receipts, understanding workflows, extracting data from documents, and summarizing reports. Code generation tasks that require long-structured outputs can also be enhanced by multimodality. Despite this, their use in commercial applications is often limited due to limited access to training data and restrictive licensing, which hinders open access. To address these limitations, we introduce BigDocs-7.5M, a high-quality, open-access dataset comprising 7.5 million multimodal documents across 30 tasks. We use an efficient data curation process to ensure our data is high-quality and license-permissive. Our process emphasizes accountability, responsibility, and transparency through filtering rules, traceable metadata, and careful content analysis. Additionally, we introduce BigDocs-Bench, a benchmark suite with 10 novel tasks where we create datasets that reflect real-world use cases involving reasoning over Graphical User Interfaces (GUI) and code generation from images. Our experiments show that training with BigDocs-Bench improves average performance up to 25.8% over closed-source GPT-4o in document reasoning and structured output tasks such as Screenshot2HTML or Image2Latex generation. Finally, human evaluations showed a preference for outputs from models trained on BigDocs over GPT-4o. This suggests that BigDocs can help both academics and the open-source community utilize and improve AI tools to enhance multimodal capabilities and document reasoning. The project is hosted at https://bigdocs.github.io .

Current multimodal models aim to transcend the limitations of single-modality representations by unifying understanding and generation, often using text-to-image (T2I) tasks to calibrate semantic consistency. However, their reliance on static, single-image generation in training and evaluation leads to overfitting to static pattern matching and semantic fusion, while fundamentally hindering their ability to model dynamic processes that unfold over time. To address these constraints, we propose Envision-a causal event progression benchmark for chained text-to-multi-image generation. Grounded in world knowledge and structured by spatiotemporal causality, it reorganizes existing evaluation dimensions and includes 1,000 four-stage prompts spanning six scientific and humanities domains. To transition evaluation from single images to sequential frames and assess whether models truly internalize world knowledge while adhering to causal-temporal constraints, we introduce Envision-Score, a holistic metric integrating multi-dimensional consistency, physicality, and aesthetics. Comprehensive evaluation of 15 models (10 specialized T2I models, 5 unified models) uncovers: specialized T2I models demonstrate proficiency in aesthetic rendering yet lack intrinsic world knowledge. Unified multimodal models bridge this gap, consistently outperforming specialized counterparts in causal narrative coherence. However, even these unified architectures remain subordinate to closed-source models and struggle to overcome the core challenge of spatiotemporal consistency. This demonstrates that a focus on causally-isolated single images impedes multi-frame reasoning and generation, promoting static pattern matching over dynamic world modeling-ultimately limiting world knowledge internalization, generation.

Multimodal large language models (MLLMs) that integrate visual and textual reasoning leverage chain-of-thought (CoT) prompting to tackle complex visual tasks, yet continue to exhibit visual hallucinations and an over-reliance on textual priors. We present a systematic diagnosis of state-of-the-art vision-language models using a three-stage evaluation framework, uncovering key failure modes. To address these, we propose an agent-based architecture that combines LLM reasoning with lightweight visual modules, enabling fine-grained analysis and iterative refinement of reasoning chains. Our results highlight future visual reasoning models should focus on integrating a broader set of specialized tools for analyzing visual content. Our system achieves significant gains (+10.3 on MMMU, +6.0 on MathVista over a 7B baseline), matching or surpassing much larger models. We will release our framework and evaluation suite to facilitate future research.

This study explores the capabilities of multimodal large language models (LLMs) in handling challenging multistep tasks that integrate language and vision, focusing on model steerability, composability, and the application of long-term memory and context understanding. The problem addressed is the LLM's ability (Nov 2023 GPT-4 Vision Preview) to manage tasks that require synthesizing visual and textual information, especially where stepwise instructions and sequential logic are paramount. The research presents a series of 14 creatively and constructively diverse tasks, ranging from AI Lego Designing to AI Satellite Image Analysis, designed to test the limits of current LLMs in contexts that previously proved difficult without extensive memory and contextual understanding. Key findings from evaluating 800 guided dialogs include notable disparities in task completion difficulty. For instance, 'Image to Ingredient AI Bartender' (Low difficulty) contrasted sharply with 'AI Game Self-Player' (High difficulty), highlighting the LLM's varying proficiency in processing complex visual data and generating coherent instructions. Tasks such as 'AI Genetic Programmer' and 'AI Negotiator' showed high completion difficulty, emphasizing challenges in maintaining context over multiple steps. The results underscore the importance of developing LLMs that combine long-term memory and contextual awareness to mimic human-like thought processes in complex problem-solving scenarios.

Strong Artificial Intelligence (Strong AI) or Artificial General Intelligence (AGI) with abstract reasoning ability is the goal of next-generation AI. Recent advancements in Large Language Models (LLMs), along with the emerging field of Multimodal Large Language Models (MLLMs), have demonstrated impressive capabilities across a wide range of multimodal tasks and applications. Particularly, various MLLMs, each with distinct model architectures, training data, and training stages, have been evaluated across a broad range of MLLM benchmarks. These studies have, to varying degrees, revealed different aspects of the current capabilities of MLLMs. However, the reasoning abilities of MLLMs have not been systematically investigated. In this survey, we comprehensively review the existing evaluation protocols of multimodal reasoning, categorize and illustrate the frontiers of MLLMs, introduce recent trends in applications of MLLMs on reasoning-intensive tasks, and finally discuss current practices and future directions. We believe our survey establishes a solid base and sheds light on this important topic, multimodal reasoning.

Conversational generative AI has demonstrated remarkable promise for empowering biomedical practitioners, but current investigations focus on unimodal text. Multimodal conversational AI has seen rapid progress by leveraging billions of image-text pairs from the public web, but such general-domain vision-language models still lack sophistication in understanding and conversing about biomedical images. In this paper, we propose a cost-efficient approach for training a vision-language conversational assistant that can answer open-ended research questions of biomedical images. The key idea is to leverage a large-scale, broad-coverage biomedical figure-caption dataset extracted from PubMed Central, use GPT-4 to self-instruct open-ended instruction-following data from the captions, and then fine-tune a large general-domain vision-language model using a novel curriculum learning method. Specifically, the model first learns to align biomedical vocabulary using the figure-caption pairs as is, then learns to master open-ended conversational semantics using GPT-4 generated instruction-following data, broadly mimicking how a layperson gradually acquires biomedical knowledge. This enables us to train a Large Language and Vision Assistant for BioMedicine (LLaVA-Med) in less than 15 hours (with eight A100s). LLaVA-Med exhibits excellent multimodal conversational capability and can follow open-ended instruction to assist with inquiries about a biomedical image. On three standard biomedical visual question answering datasets, LLaVA-Med outperforms previous supervised state-of-the-art on certain metrics. To facilitate biomedical multimodal research, we will release our instruction-following data and the LLaVA-Med model.

The rapid progress of Large Multimodal Models (LMMs) and cloud-based AI agents is transforming human-AI collaboration into bidirectional, multimodal interaction. However, existing codecs remain optimized for unimodal, one-way communication, resulting in repeated degradation under conventional compress-transmit-reconstruct pipelines. To address this limitation, we propose UniMIC, a Unified token-based Multimodal Interactive Coding framework that bridges edge devices and cloud AI agents. Instead of transmitting raw pixels or plain text, UniMIC employs compact tokenized representations as the communication medium, enabling efficient low-bitrate transmission while maintaining compatibility with LMMs. To further enhance compression, lightweight Transformer-based entropy models with scenario-specific designs-generic, masked, and text-conditioned-effectively minimize inter-token redundancy. Extensive experiments on text-to-image generation, text-guided inpainting, outpainting, and visual question answering show that UniMIC achieves substantial bitrate savings and remains robust even at ultra-low bitrates (<0.05bpp), without compromising downstream task performance. These results establish UniMIC as a practical and forward-looking paradigm for next-generation multimodal interactive communication.

The automation of scientific discovery represents a critical milestone in Artificial Intelligence (AI) research. However, existing agentic systems for science suffer from two fundamental limitations: rigid, pre-programmed workflows that cannot adapt to intermediate findings, and inadequate context management that hinders long-horizon research. We present freephdlabor, an open-source multiagent framework featuring fully dynamic workflows determined by real-time agent reasoning and a \textit{modular architecture} enabling seamless customization -- users can modify, add, or remove agents to address domain-specific requirements. The framework provides comprehensive infrastructure including automatic context compaction, workspace-based communication to prevent information degradation, memory persistence across sessions, and non-blocking human intervention mechanisms. These features collectively transform automated research from isolated, single-run attempts into continual research programs that build systematically on prior explorations and incorporate human feedback. By providing both the architectural principles and practical implementation for building customizable co-scientist systems, this work aims to facilitate broader adoption of automated research across scientific domains, enabling practitioners to deploy interactive multiagent systems that autonomously conduct end-to-end research -- from ideation through experimentation to publication-ready manuscripts.

Current multimodal and multitask foundation models like 4M or UnifiedIO show promising results, but in practice their out-of-the-box abilities to accept diverse inputs and perform diverse tasks are limited by the (usually rather small) number of modalities and tasks they are trained on. In this paper, we expand upon the capabilities of them by training a single model on tens of highly diverse modalities and by performing co-training on large-scale multimodal datasets and text corpora. This includes training on several semantic and geometric modalities, feature maps from recent state of the art models like DINOv2 and ImageBind, pseudo labels of specialist models like SAM and 4DHumans, and a range of new modalities that allow for novel ways to interact with the model and steer the generation, for example image metadata or color palettes. A crucial step in this process is performing discrete tokenization on various modalities, whether they are image-like, neural network feature maps, vectors, structured data like instance segmentation or human poses, or data that can be represented as text. Through this, we expand on the out-of-the-box capabilities of multimodal models and specifically show the possibility of training one model to solve at least 3x more tasks/modalities than existing ones and doing so without a loss in performance. This enables more fine-grained and controllable multimodal generation capabilities and allows us to study the distillation of models trained on diverse data and objectives into a unified model. We successfully scale the training to a three billion parameter model using tens of modalities and different datasets. The resulting models and training code are open sourced at 4m.epfl.ch.

Multimodal AI models are increasingly used in fields like healthcare, finance, and autonomous driving, where information is drawn from multiple sources or modalities such as images, texts, audios, videos. However, effectively managing uncertainty - arising from noise, insufficient evidence, or conflicts between modalities - is crucial for reliable decision-making. Current uncertainty-aware machine learning methods leveraging, for example, evidence averaging, or evidence accumulation underestimate uncertainties in high-conflict scenarios. Moreover, the state-of-the-art evidence averaging strategy is not order invariant and fails to scale to multiple modalities. To address these challenges, we propose a novel multimodal learning method with order-invariant evidence fusion and introduce a conflict-based discounting mechanism that reallocates uncertain mass when unreliable modalities are detected. We provide both theoretical analysis and experimental validation, demonstrating that unlike the previous work, the proposed approach effectively distinguishes between conflicting and non-conflicting samples based on the provided uncertainty estimates, and outperforms the previous models in uncertainty-based conflict detection.

Reasoning lies at the heart of intelligence, shaping the ability to make decisions, draw conclusions, and generalize across domains. In artificial intelligence, as systems increasingly operate in open, uncertain, and multimodal environments, reasoning becomes essential for enabling robust and adaptive behavior. Large Multimodal Reasoning Models (LMRMs) have emerged as a promising paradigm, integrating modalities such as text, images, audio, and video to support complex reasoning capabilities and aiming to achieve comprehensive perception, precise understanding, and deep reasoning. As research advances, multimodal reasoning has rapidly evolved from modular, perception-driven pipelines to unified, language-centric frameworks that offer more coherent cross-modal understanding. While instruction tuning and reinforcement learning have improved model reasoning, significant challenges remain in omni-modal generalization, reasoning depth, and agentic behavior. To address these issues, we present a comprehensive and structured survey of multimodal reasoning research, organized around a four-stage developmental roadmap that reflects the field's shifting design philosophies and emerging capabilities. First, we review early efforts based on task-specific modules, where reasoning was implicitly embedded across stages of representation, alignment, and fusion. Next, we examine recent approaches that unify reasoning into multimodal LLMs, with advances such as Multimodal Chain-of-Thought (MCoT) and multimodal reinforcement learning enabling richer and more structured reasoning chains. Finally, drawing on empirical insights from challenging benchmarks and experimental cases of OpenAI O3 and O4-mini, we discuss the conceptual direction of native large multimodal reasoning models (N-LMRMs), which aim to support scalable, agentic, and adaptive reasoning and planning in complex, real-world environments.

Rapid development of artificial intelligence has drastically accelerated the development of scientific discovery. Trained with large-scale observation data, deep neural networks extract the underlying patterns in an end-to-end manner and assist human researchers with highly-precised predictions in unseen scenarios. The recent rise of Large Language Models (LLMs) and the empowered autonomous agents enable scientists to gain help through interaction in different stages of their research, including but not limited to literature review, research ideation, idea implementation, and academic writing. However, AI researchers instantiated by foundation model empowered agents with full-process autonomy are still in their infancy. In this paper, we study AI-Generated Science (AIGS), where agents independently and autonomously complete the entire research process and discover scientific laws. By revisiting the definition of scientific research, we argue that falsification is the essence of both human research process and the design of an AIGS system. Through the lens of falsification, prior systems attempting towards AI-Generated Science either lack the part in their design, or rely heavily on existing verification engines that narrow the use in specialized domains. In this work, we propose Baby-AIGS as a baby-step demonstration of a full-process AIGS system, which is a multi-agent system with agents in roles representing key research process. By introducing FalsificationAgent, which identify and then verify possible scientific discoveries, we empower the system with explicit falsification. Experiments on three tasks preliminarily show that Baby-AIGS could produce meaningful scientific discoveries, though not on par with experienced human researchers. Finally, we discuss on the limitations of current Baby-AIGS, actionable insights, and related ethical issues in detail.

Information comes in diverse modalities. Multimodal native AI models are essential to integrate real-world information and deliver comprehensive understanding. While proprietary multimodal native models exist, their lack of openness imposes obstacles for adoptions, let alone adaptations. To fill this gap, we introduce Aria, an open multimodal native model with best-in-class performance across a wide range of multimodal, language, and coding tasks. Aria is a mixture-of-expert model with 3.9B and 3.5B activated parameters per visual token and text token, respectively. It outperforms Pixtral-12B and Llama3.2-11B, and is competitive against the best proprietary models on various multimodal tasks. We pre-train Aria from scratch following a 4-stage pipeline, which progressively equips the model with strong capabilities in language understanding, multimodal understanding, long context window, and instruction following. We open-source the model weights along with a codebase that facilitates easy adoptions and adaptations of Aria in real-world applications.

Recent advancements in AI have led to the development of large multimodal models (LMMs) capable of processing complex tasks involving joint reasoning over text and visual content in the image (e.g., navigating maps in public places). This paper introduces ConTextual, a novel benchmark comprising instructions designed explicitly to evaluate LMMs' ability to perform context-sensitive text-rich visual reasoning. ConTextual emphasizes diverse real-world scenarios (e.g., time-reading, navigation, shopping and more) demanding a deeper understanding of the interactions between textual and visual elements. Our findings reveal a significant performance gap of 30.8% between the best-performing LMM, GPT-4V(ision), and human capabilities using human evaluation indicating substantial room for improvement in context-sensitive text-rich visual reasoning. Notably, while GPT-4V excelled in abstract categories like meme and quote interpretation, its overall performance still lagged behind humans. In addition to human evaluations, we also employed automatic evaluation metrics using GPT-4, uncovering similar trends in performance disparities. We also perform a fine-grained evaluation across diverse visual contexts and provide qualitative analysis which provides a robust framework for future advancements in the LMM design. https://con-textual.github.io/

Multimodal reasoning remains a fundamental challenge in artificial intelligence. Despite substantial advances in text-based reasoning, even state-of-the-art models such as GPT-o3 struggle to maintain strong performance in multimodal scenarios. To address this gap, we introduce a caption-assisted reasoning framework that effectively bridges visual and textual modalities. Our approach achieved 1st place in the ICML 2025 AI for Math Workshop \& Challenge 2: SeePhys, highlighting its effectiveness and robustness. Furthermore, we validate its generalization on the MathVerse benchmark for geometric reasoning, demonstrating the versatility of our method. Our code is publicly available at https://github.com/OpenDCAI/SciReasoner.

Language models have recently advanced into the realm of reasoning, yet it is through multimodal reasoning that we can fully unlock the potential to achieve more comprehensive, human-like cognitive capabilities. This survey provides a systematic overview of the recent multimodal reasoning approaches, categorizing them into two levels: language-centric multimodal reasoning and collaborative multimodal reasoning. The former encompasses one-pass visual perception and active visual perception, where vision primarily serves a supporting role in language reasoning. The latter involves action generation and state update within reasoning process, enabling a more dynamic interaction between modalities. Furthermore, we analyze the technical evolution of these methods, discuss their inherent challenges, and introduce key benchmark tasks and evaluation metrics for assessing multimodal reasoning performance. Finally, we provide insights into future research directions from the following two perspectives: (i) from visual-language reasoning to omnimodal reasoning and (ii) from multimodal reasoning to multimodal agents. This survey aims to provide a structured overview that will inspire further advancements in multimodal reasoning research.

Multimodal learning is a rapidly growing research field that has revolutionized multitasking and generative modeling in AI. While much of the research has focused on dealing with unstructured data (e.g., language, images, audio, or video), structured data (e.g., tabular data, time series, or signals) has received less attention. However, many industry-relevant use cases involve or can be benefited from both types of data. In this work, we propose a modular, end-to-end multimodal learning method called MAGNUM, which can natively handle both structured and unstructured data. MAGNUM is flexible enough to employ any specialized unimodal module to extract, compress, and fuse information from all available modalities.

Despite rapid advances in vision-language models (VLMs), current benchmarks for multimodal reasoning fall short in three key dimensions. First, they overwhelmingly rely on static images, failing to capture the temporal complexity of real-world environments. Second, they narrowly focus on mathematical problem-solving, neglecting the broader spectrum of reasoning skills -- including abstract, physical, planning, spatial, and temporal capabilities -- required for robust multimodal intelligence. Third, many benchmarks quickly saturate, offering limited headroom for diagnosing failure modes or measuring continued progress. We introduce MORSE-500 (Multimodal Reasoning Stress-test Environment), a video benchmark composed of 500 fully scripted clips with embedded questions spanning six complementary reasoning categories. Each instance is programmatically generated using deterministic Python scripts (via Manim, Matplotlib, MoviePy), generative video models, and curated real footage. This script-driven design allows fine-grained control over visual complexity, distractor density, and temporal dynamics -- enabling difficulty to be scaled systematically as models improve. Unlike static benchmarks that become obsolete once saturated, MORSE-500 is built to evolve: its controllable generation pipeline supports the creation of arbitrarily challenging new instances, making it ideally suited for stress-testing next-generation models. Initial experiments with state-of-the-art systems -- including various Gemini 2.5 Pro and OpenAI o3 which represent the strongest available at the time, alongside strong open-source models -- reveal substantial performance gaps across all categories, with particularly large deficits in abstract and planning tasks. We release the full dataset, generation scripts, and evaluation harness to support transparent, reproducible, and forward-looking multimodal reasoning research.

Vision-Language Models (VLMs) based on Mixture-of-Experts (MoE) architectures have emerged as a pivotal paradigm in multimodal understanding, offering a powerful framework for integrating visual and linguistic information. However, the increasing complexity and diversity of tasks present significant challenges in coordinating load balancing across heterogeneous visual experts, where optimizing one specialist's performance often compromises others' capabilities. To address task heterogeneity and expert load imbalance, we propose Astrea, a novel multi-expert collaborative VLM architecture based on progressive pre-alignment. Astrea introduces three key innovations: 1) A heterogeneous expert coordination mechanism that integrates four specialized models (detection, segmentation, classification, captioning) into a comprehensive expert matrix covering essential visual comprehension elements; 2) A dynamic knowledge fusion strategy featuring progressive pre-alignment to harmonize experts within the VLM latent space through contrastive learning, complemented by probabilistically activated stochastic residual connections to preserve knowledge continuity; 3) An enhanced optimization framework utilizing momentum contrastive learning for long-range dependency modeling and adaptive weight allocators for real-time expert contribution calibration. Extensive evaluations across 12 benchmark tasks spanning VQA, image captioning, and cross-modal retrieval demonstrate Astrea's superiority over state-of-the-art models, achieving an average performance gain of +4.7\%. This study provides the first empirical demonstration that progressive pre-alignment strategies enable VLMs to overcome task heterogeneity limitations, establishing new methodological foundations for developing general-purpose multimodal agents.

Web agents such as Deep Research have demonstrated superhuman cognitive abilities, capable of solving highly challenging information-seeking problems. However, most research remains primarily text-centric, overlooking visual information in the real world. This makes multimodal Deep Research highly challenging, as such agents require much stronger reasoning abilities in perception, logic, knowledge, and the use of more sophisticated tools compared to text-based agents. To address this limitation, we introduce WebWatcher, a multi-modal Agent for Deep Research equipped with enhanced visual-language reasoning capabilities. It leverages high-quality synthetic multimodal trajectories for efficient cold start training, utilizes various tools for deep reasoning, and further enhances generalization through reinforcement learning. To better evaluate the capabilities of multimodal agents, we propose BrowseComp-VL, a benchmark with BrowseComp-style that requires complex information retrieval involving both visual and textual information. Experimental results show that WebWatcher significantly outperforms proprietary baseline, RAG workflow and open-source agents in four challenging VQA benchmarks, which paves the way for solving complex multimodal information-seeking tasks.

Artificial intelligence (AI) has achieved astonishing successes in many domains, especially with the recent breakthroughs in the development of foundational large models. These large models, leveraging their extensive training data, provide versatile solutions for a wide range of downstream tasks. However, as modern datasets become increasingly diverse and complex, the development of large AI models faces two major challenges: (1) the enormous consumption of computational resources and deployment difficulties, and (2) the difficulty in fitting heterogeneous and complex data, which limits the usability of the models. Mixture of Experts (MoE) models has recently attracted much attention in addressing these challenges, by dynamically selecting and activating the most relevant sub-models to process input data. It has been shown that MoEs can significantly improve model performance and efficiency with fewer resources, particularly excelling in handling large-scale, multimodal data. Given the tremendous potential MoE has demonstrated across various domains, it is urgent to provide a comprehensive summary of recent advancements of MoEs in many important fields. Existing surveys on MoE have their limitations, e.g., being outdated or lacking discussion on certain key areas, and we aim to address these gaps. In this paper, we first introduce the basic design of MoE, including gating functions, expert networks, routing mechanisms, training strategies, and system design. We then explore the algorithm design of MoE in important machine learning paradigms such as continual learning, meta-learning, multi-task learning, and reinforcement learning. Additionally, we summarize theoretical studies aimed at understanding MoE and review its applications in computer vision and natural language processing. Finally, we discuss promising future research directions.

This survey examines the rapidly evolving field of Deep Research systems -- AI-powered applications that automate complex research workflows through the integration of large language models, advanced information retrieval, and autonomous reasoning capabilities. We analyze more than 80 commercial and non-commercial implementations that have emerged since 2023, including OpenAI/Deep Research, Gemini/Deep Research, Perplexity/Deep Research, and numerous open-source alternatives. Through comprehensive examination, we propose a novel hierarchical taxonomy that categorizes systems according to four fundamental technical dimensions: foundation models and reasoning engines, tool utilization and environmental interaction, task planning and execution control, and knowledge synthesis and output generation. We explore the architectural patterns, implementation approaches, and domain-specific adaptations that characterize these systems across academic, scientific, business, and educational applications. Our analysis reveals both the significant capabilities of current implementations and the technical and ethical challenges they present regarding information accuracy, privacy, intellectual property, and accessibility. The survey concludes by identifying promising research directions in advanced reasoning architectures, multimodal integration, domain specialization, human-AI collaboration, and ecosystem standardization that will likely shape the future evolution of this transformative technology. By providing a comprehensive framework for understanding Deep Research systems, this survey contributes to both the theoretical understanding of AI-augmented knowledge work and the practical development of more capable, responsible, and accessible research technologies. The paper resources can be viewed at https://github.com/scienceaix/deepresearch.

In many machine learning systems that jointly learn from multiple modalities, a core research question is to understand the nature of multimodal interactions: the emergence of new task-relevant information during learning from both modalities that was not present in either alone. We study this challenge of interaction quantification in a semi-supervised setting with only labeled unimodal data and naturally co-occurring multimodal data (e.g., unlabeled images and captions, video and corresponding audio) but when labeling them is time-consuming. Using a precise information-theoretic definition of interactions, our key contributions are the derivations of lower and upper bounds to quantify the amount of multimodal interactions in this semi-supervised setting. We propose two lower bounds based on the amount of shared information between modalities and the disagreement between separately trained unimodal classifiers, and derive an upper bound through connections to approximate algorithms for min-entropy couplings. We validate these estimated bounds and show how they accurately track true interactions. Finally, two semi-supervised multimodal applications are explored based on these theoretical results: (1) analyzing the relationship between multimodal performance and estimated interactions, and (2) self-supervised learning that embraces disagreement between modalities beyond agreement as is typically done.

Despite a surge collection of XAI methods, users still struggle to obtain required AI explanations. Previous research suggests chatbots as dynamic solutions, but the effective design of conversational XAI agents for practical human needs remains under-explored. This paper focuses on Conversational XAI for AI-assisted scientific writing tasks. Drawing from human linguistic theories and formative studies, we identify four design rationales: "multifaceted", "controllability", "mix-initiative", "context-aware drill-down". We incorporate them into an interactive prototype, ConvXAI, which facilitates heterogeneous AI explanations for scientific writing through dialogue. In two studies with 21 users, ConvXAI outperforms a GUI-based baseline on improving human-perceived understanding and writing improvement. The paper further discusses the practical human usage patterns in interacting with ConvXAI for scientific co-writing.

The evolution of Artificial Intelligence (AI) has been significantly accelerated by advancements in Large Language Models (LLMs) and Large Multimodal Models (LMMs), gradually showcasing potential cognitive reasoning abilities in problem-solving and scientific discovery (i.e., AI4Science) once exclusive to human intellect. To comprehensively evaluate current models' performance in cognitive reasoning abilities, we introduce OlympicArena, which includes 11,163 bilingual problems across both text-only and interleaved text-image modalities. These challenges encompass a wide range of disciplines spanning seven fields and 62 international Olympic competitions, rigorously examined for data leakage. We argue that the challenges in Olympic competition problems are ideal for evaluating AI's cognitive reasoning due to their complexity and interdisciplinary nature, which are essential for tackling complex scientific challenges and facilitating discoveries. Beyond evaluating performance across various disciplines using answer-only criteria, we conduct detailed experiments and analyses from multiple perspectives. We delve into the models' cognitive reasoning abilities, their performance across different modalities, and their outcomes in process-level evaluations, which are vital for tasks requiring complex reasoning with lengthy solutions. Our extensive evaluations reveal that even advanced models like GPT-4o only achieve a 39.97% overall accuracy, illustrating current AI limitations in complex reasoning and multimodal integration. Through the OlympicArena, we aim to advance AI towards superintelligence, equipping it to address more complex challenges in science and beyond. We also provide a comprehensive set of resources to support AI research, including a benchmark dataset, an open-source annotation platform, a detailed evaluation tool, and a leaderboard with automatic submission features.

Over the past decade, wearable computing devices (``smart glasses'') have undergone remarkable advancements in sensor technology, design, and processing power, ushering in a new era of opportunity for high-density human behavior data. Equipped with wearable cameras, these glasses offer a unique opportunity to analyze non-verbal behavior in natural settings as individuals interact. Our focus lies in predicting engagement in dyadic interactions by scrutinizing verbal and non-verbal cues, aiming to detect signs of disinterest or confusion. Leveraging such analyses may revolutionize our understanding of human communication, foster more effective collaboration in professional environments, provide better mental health support through empathetic virtual interactions, and enhance accessibility for those with communication barriers. In this work, we collect a dataset featuring 34 participants engaged in casual dyadic conversations, each providing self-reported engagement ratings at the end of each conversation. We introduce a novel fusion strategy using Large Language Models (LLMs) to integrate multiple behavior modalities into a ``multimodal transcript'' that can be processed by an LLM for behavioral reasoning tasks. Remarkably, this method achieves performance comparable to established fusion techniques even in its preliminary implementation, indicating strong potential for further research and optimization. This fusion method is one of the first to approach ``reasoning'' about real-world human behavior through a language model. Smart glasses provide us the ability to unobtrusively gather high-density multimodal data on human behavior, paving the way for new approaches to understanding and improving human communication with the potential for important societal benefits. The features and data collected during the studies will be made publicly available to promote further research.

This paper reviews the MARS2 2025 Challenge on Multimodal Reasoning. We aim to bring together different approaches in multimodal machine learning and LLMs via a large benchmark. We hope it better allows researchers to follow the state-of-the-art in this very dynamic area. Meanwhile, a growing number of testbeds have boosted the evolution of general-purpose large language models. Thus, this year's MARS2 focuses on real-world and specialized scenarios to broaden the multimodal reasoning applications of MLLMs. Our organizing team released two tailored datasets Lens and AdsQA as test sets, which support general reasoning in 12 daily scenarios and domain-specific reasoning in advertisement videos, respectively. We evaluated 40+ baselines that include both generalist MLLMs and task-specific models, and opened up three competition tracks, i.e., Visual Grounding in Real-world Scenarios (VG-RS), Visual Question Answering with Spatial Awareness (VQA-SA), and Visual Reasoning in Creative Advertisement Videos (VR-Ads). Finally, 76 teams from the renowned academic and industrial institutions have registered and 40+ valid submissions (out of 1200+) have been included in our ranking lists. Our datasets, code sets (40+ baselines and 15+ participants' methods), and rankings are publicly available on the MARS2 workshop website and our GitHub organization page https://github.com/mars2workshop/, where our updates and announcements of upcoming events will be continuously provided.

Multimodal learning enhances the perceptual capabilities of cognitive systems by integrating information from different sensory modalities. However, existing multimodal fusion research typically assumes static integration, not fully incorporating key dynamic mechanisms found in the brain. Specifically, the brain exhibits an inverse effectiveness phenomenon, wherein weaker unimodal cues yield stronger multisensory integration benefits; conversely, when individual modal cues are stronger, the effect of fusion is diminished. This mechanism enables biological systems to achieve robust cognition even with scarce or noisy perceptual cues. Inspired by this biological mechanism, we explore the relationship between multimodal output and information from individual modalities, proposing an inverse effectiveness driven multimodal fusion (IEMF) strategy. By incorporating this strategy into neural networks, we achieve more efficient integration with improved model performance and computational efficiency, demonstrating up to 50% reduction in computational cost across diverse fusion methods. We conduct experiments on audio-visual classification, continual learning, and question answering tasks to validate our method. Results consistently demonstrate that our method performs excellently in these tasks. To verify universality and generalization, we also conduct experiments on Artificial Neural Networks (ANN) and Spiking Neural Networks (SNN), with results showing good adaptability to both network types. Our research emphasizes the potential of incorporating biologically inspired mechanisms into multimodal networks and provides promising directions for the future development of multimodal artificial intelligence. The code is available at https://github.com/Brain-Cog-Lab/IEMF.

Multimodal Large Language Models (MLLMs) excel in solving text-based mathematical problems, but they struggle with mathematical diagrams since they are primarily trained on natural scene images. For humans, visual aids generally enhance problem-solving, but MLLMs perform worse as information shifts from textual to visual modality. This decline is mainly due to their shortcomings in aligning images and text. To tackle aforementioned challenges, we propose Math-PUMA, a methodology focused on Progressive Upward Multimodal Alignment. This approach is designed to improve the mathematical reasoning skills of MLLMs through a three-stage training process, with the second stage being the critical alignment stage. We first enhance the language model's mathematical reasoning capabilities with extensive set of textual mathematical problems. We then construct a multimodal dataset with varying degrees of textual and visual information, creating data pairs by presenting each problem in at least two forms. By leveraging the Kullback-Leibler (KL) divergence of next-token prediction distributions to align visual and textual modalities, consistent problem-solving abilities are ensured. Finally, we utilize multimodal instruction tuning for MLLMs with high-quality multimodal data. Experimental results on multiple mathematical reasoning benchmarks demonstrate that the MLLMs trained with Math-PUMA surpass most open-source MLLMs. Our approach effectively narrows the performance gap for problems presented in different modalities. The code and data are available at: https://github.com/wwzhuang01/Math-PUMA.

Combining pre-trained expert models offers substantial potential for scalable multimodal reasoning, but building a unified framework remains challenging due to the increasing diversity of input modalities and task complexity. For instance, medical diagnosis requires precise reasoning over structured clinical tables, while financial forecasting depends on interpreting plot-based data to make informed predictions. To tackle this challenge, we introduce MEXA, a training-free framework that performs modality- and task-aware aggregation of multiple expert models to enable effective multimodal reasoning across diverse and distinct domains. MEXA dynamically selects expert models based on the input modality and the task-specific reasoning demands (i.e., skills). Each expert model, specialized in a modality task pair, generates interpretable textual reasoning outputs. MEXA then aggregates and reasons over these outputs using a Large Reasoning Model (LRM) to produce the final answer. This modular design allows flexible and transparent multimodal reasoning across diverse domains without additional training overhead. We extensively evaluate our approach on diverse multimodal benchmarks, including Video Reasoning, Audio Reasoning, 3D Understanding, and Medical QA. MEXA consistently delivers performance improvements over strong multimodal baselines, highlighting the effectiveness and broad applicability of our expert-driven selection and aggregation in diverse multimodal reasoning tasks.

Cross-modal reasoning (CMR), the intricate process of synthesizing and drawing inferences across divergent sensory modalities, is increasingly recognized as a crucial capability in the progression toward more sophisticated and anthropomorphic artificial intelligence systems. Large Language Models (LLMs) represent a class of AI algorithms specifically engineered to parse, produce, and engage with human language on an extensive scale. The recent trend of deploying LLMs to tackle CMR tasks has marked a new mainstream of approaches for enhancing their effectiveness. This survey offers a nuanced exposition of current methodologies applied in CMR using LLMs, classifying these into a detailed three-tiered taxonomy. Moreover, the survey delves into the principal design strategies and operational techniques of prototypical models within this domain. Additionally, it articulates the prevailing challenges associated with the integration of LLMs in CMR and identifies prospective research directions. To sum up, this survey endeavors to expedite progress within this burgeoning field by endowing scholars with a holistic and detailed vista, showcasing the vanguard of current research whilst pinpointing potential avenues for advancement. An associated GitHub repository that collects the relevant papers can be found at https://github.com/ZuyiZhou/Awesome-Cross-modal-Reasoning-with-LLMs

Multimodal models have gained significant success in recent years. Standard multimodal approaches often assume unchanged modalities from training stage to inference stage. In practice, however, many scenarios fail to satisfy such assumptions with missing modalities during inference, leading to limitations on where multimodal models can be applied. While existing methods mitigate the problem through reconstructing the missing modalities, it increases unnecessary computational cost, which could be just as critical, especially for large, deployed systems. To solve the problem from both sides, we propose a novel guidance network that promotes knowledge sharing during training, taking advantage of the multimodal representations to train better single-modality models for inference. Real-life experiment in violence detection shows that our proposed framework trains single-modality models that significantly outperform its traditionally trained counterparts while maintaining the same inference cost.

One of the grand challenges of artificial general intelligence is developing agents capable of conducting scientific research and discovering new knowledge. While frontier models have already been used as aids to human scientists, e.g. for brainstorming ideas, writing code, or prediction tasks, they still conduct only a small part of the scientific process. This paper presents the first comprehensive framework for fully automatic scientific discovery, enabling frontier large language models to perform research independently and communicate their findings. We introduce The AI Scientist, which generates novel research ideas, writes code, executes experiments, visualizes results, describes its findings by writing a full scientific paper, and then runs a simulated review process for evaluation. In principle, this process can be repeated to iteratively develop ideas in an open-ended fashion, acting like the human scientific community. We demonstrate its versatility by applying it to three distinct subfields of machine learning: diffusion modeling, transformer-based language modeling, and learning dynamics. Each idea is implemented and developed into a full paper at a cost of less than $15 per paper. To evaluate the generated papers, we design and validate an automated reviewer, which we show achieves near-human performance in evaluating paper scores. The AI Scientist can produce papers that exceed the acceptance threshold at a top machine learning conference as judged by our automated reviewer. This approach signifies the beginning of a new era in scientific discovery in machine learning: bringing the transformative benefits of AI agents to the entire research process of AI itself, and taking us closer to a world where endless affordable creativity and innovation can be unleashed on the world's most challenging problems. Our code is open-sourced at https://github.com/SakanaAI/AI-Scientist

Understanding the current capabilities and risks of AI Scientist systems is essential for ensuring trustworthy and sustainable AI-driven scientific progress while preserving the integrity of the academic ecosystem. To this end, we develop Jr. AI Scientist, a state-of-the-art autonomous AI scientist system that mimics the core research workflow of a novice student researcher: Given the baseline paper from the human mentor, it analyzes its limitations, formulates novel hypotheses for improvement, validates them through rigorous experimentation, and writes a paper with the results. Unlike previous approaches that assume full automation or operate on small-scale code, Jr. AI Scientist follows a well-defined research workflow and leverages modern coding agents to handle complex, multi-file implementations, leading to scientifically valuable contributions. For evaluation, we conducted automated assessments using AI Reviewers, author-led evaluations, and submissions to Agents4Science, a venue dedicated to AI-driven scientific contributions. The findings demonstrate that Jr. AI Scientist generates papers receiving higher review scores than existing fully automated systems. Nevertheless, we identify important limitations from both the author evaluation and the Agents4Science reviews, indicating the potential risks of directly applying current AI Scientist systems and key challenges for future research. Finally, we comprehensively report various risks identified during development. We hope these insights will deepen understanding of current progress and risks in AI Scientist development.

The emergence of small vision-language models (sVLMs) marks a critical advancement in multimodal AI, enabling efficient processing of visual and textual data in resource-constrained environments. This survey offers a comprehensive exploration of sVLM development, presenting a taxonomy of architectures - transformer-based, mamba-based, and hybrid - that highlight innovations in compact design and computational efficiency. Techniques such as knowledge distillation, lightweight attention mechanisms, and modality pre-fusion are discussed as enablers of high performance with reduced resource requirements. Through an in-depth analysis of models like TinyGPT-V, MiniGPT-4, and VL-Mamba, we identify trade-offs between accuracy, efficiency, and scalability. Persistent challenges, including data biases and generalization to complex tasks, are critically examined, with proposed pathways for addressing them. By consolidating advancements in sVLMs, this work underscores their transformative potential for accessible AI, setting a foundation for future research into efficient multimodal systems.

By integrating the perception capabilities of multimodal encoders with the generative power of Large Language Models (LLMs), Multimodal Large Language Models (MLLMs), exemplified by GPT-4V, have achieved great success in various multimodal tasks, pointing toward a promising pathway to artificial general intelligence. Despite this progress, the limited quality of multimodal data, poor performance on many complex downstream tasks, and inadequate evaluation protocols continue to hinder the reliability and broader applicability of MLLMs across diverse domains. Inspired by the human ability to leverage external tools for enhanced reasoning and problem-solving, augmenting MLLMs with external tools (e.g., APIs, expert models, and knowledge bases) offers a promising strategy to overcome these challenges. In this paper, we present a comprehensive survey on leveraging external tools to enhance MLLM performance. Our discussion is structured along four key dimensions about external tools: (1) how they can facilitate the acquisition and annotation of high-quality multimodal data; (2) how they can assist in improving MLLM performance on challenging downstream tasks; (3) how they enable comprehensive and accurate evaluation of MLLMs; (4) the current limitations and future directions of tool-augmented MLLMs. Through this survey, we aim to underscore the transformative potential of external tools in advancing MLLM capabilities, offering a forward-looking perspective on their development and applications. The project page of this paper is publicly available athttps://github.com/Lackel/Awesome-Tools-for-MLLMs.

The ability to organically reason over and with both text and images is a pillar of human intelligence, yet the ability of Multimodal Large Language Models (MLLMs) to perform such multimodal reasoning remains under-explored. Existing benchmarks often emphasize text-dominant reasoning or rely on shallow visual cues, failing to adequately assess integrated visual and textual reasoning. We introduce EMMA (Enhanced MultiModal reAsoning), a benchmark targeting organic multimodal reasoning across mathematics, physics, chemistry, and coding. EMMA tasks demand advanced cross-modal reasoning that cannot be addressed by reasoning independently in each modality, offering an enhanced test suite for MLLMs' reasoning capabilities. Our evaluation of state-of-the-art MLLMs on EMMA reveals significant limitations in handling complex multimodal and multi-step reasoning tasks, even with advanced techniques like Chain-of-Thought prompting and test-time compute scaling underperforming. These findings underscore the need for improved multimodal architectures and training paradigms to close the gap between human and model reasoning in multimodality.

As multimodal large language models (MLLMs) grow increasingly capable, fixed benchmarks are gradually losing their effectiveness in evaluating high-level scientific understanding. In this paper, we introduce the Multimodal Academic Cover benchmark (MAC), a live benchmark that could continuously evolve with scientific advancement and model progress. MAC leverages over 25,000 image-text pairs sourced from issues of top-tier scientific journals such as Nature, Science, and Cell, challenging MLLMs to reason across abstract visual and textual scientific content. Experiments on our most recent yearly snapshot, MAC-2025, reveal that while MLLMs demonstrate strong perceptual abilities, their cross-modal scientific reasoning remains limited. To bridge this gap, we propose DAD, a lightweight inference-time approach that enhances MLLMs by extending MLLM visual features with language space reasoning, achieving performance improvements of up to 11%. Finally, we highlight the live nature of MAC through experiments on updating journal covers and models for curation, illustrating its potential to remain aligned with the frontier of human knowledge. We release our benchmark at https://github.com/mhjiang0408/MAC_Bench.

Rapid progress in multimodal large language models (MLLMs) highlights the need to introduce challenging yet realistic benchmarks to the academic community, while existing benchmarks primarily focus on understanding simple natural images and short context. In this paper, we present MULTI as a cutting-edge benchmark for evaluating MLLMs on understanding complex tables and images, and reasoning with long context. MULTI provides multimodal inputs and requires responses that are either precise or open-ended, reflecting real-life examination styles. MULTI includes over 18,000 questions and challenges MLLMs with a variety of tasks, ranging from formula derivation to image detail analysis and cross-modality reasoning. We also introduce MULTI-Elite, a 500-question selected hard subset, and MULTI-Extend, with more than 4,500 external knowledge context pieces. Our evaluation indicates significant potential for MLLM advancement, with GPT-4V achieving a 63.7% accuracy rate on MULTI, in contrast to other MLLMs scoring between 28.5% and 55.3%. MULTI serves not only as a robust evaluation platform but also paves the way for the development of expert-level AI.

The advent of Large Language Models (LLMs) has significantly reshaped the trajectory of the AI revolution. Nevertheless, these LLMs exhibit a notable limitation, as they are primarily adept at processing textual information. To address this constraint, researchers have endeavored to integrate visual capabilities with LLMs, resulting in the emergence of Vision-Language Models (VLMs). These advanced models are instrumental in tackling more intricate tasks such as image captioning and visual question answering. In our comprehensive survey paper, we delve into the key advancements within the realm of VLMs. Our classification organizes VLMs into three distinct categories: models dedicated to vision-language understanding, models that process multimodal inputs to generate unimodal (textual) outputs and models that both accept and produce multimodal inputs and outputs.This classification is based on their respective capabilities and functionalities in processing and generating various modalities of data.We meticulously dissect each model, offering an extensive analysis of its foundational architecture, training data sources, as well as its strengths and limitations wherever possible, providing readers with a comprehensive understanding of its essential components. We also analyzed the performance of VLMs in various benchmark datasets. By doing so, we aim to offer a nuanced understanding of the diverse landscape of VLMs. Additionally, we underscore potential avenues for future research in this dynamic domain, anticipating further breakthroughs and advancements.

Agentic multimodal models should not only comprehend text and images, but also actively invoke external tools, such as code execution environments and web search, and integrate these operations into reasoning. In this work, we introduce DeepEyesV2 and explore how to build an agentic multimodal model from the perspectives of data construction, training methods, and model evaluation. We observe that direct reinforcement learning alone fails to induce robust tool-use behavior. This phenomenon motivates a two-stage training pipeline: a cold-start stage to establish tool-use patterns, and reinforcement learning stage to further refine tool invocation. We curate a diverse, moderately challenging training dataset, specifically including examples where tool use is beneficial. We further introduce RealX-Bench, a comprehensive benchmark designed to evaluate real-world multimodal reasoning, which inherently requires the integration of multiple capabilities, including perception, search, and reasoning. We evaluate DeepEyesV2 on RealX-Bench and other representative benchmarks, demonstrating its effectiveness across real-world understanding, mathematical reasoning, and search-intensive tasks. Moreover, DeepEyesV2 exhibits task-adaptive tool invocation, tending to use image operations for perception tasks and numerical computations for reasoning tasks. Reinforcement learning further enables complex tool combinations and allows model to selectively invoke tools based on context. We hope our study can provide guidance for community in developing agentic multimodal models.

We propose MM-REACT, a system paradigm that integrates ChatGPT with a pool of vision experts to achieve multimodal reasoning and action. In this paper, we define and explore a comprehensive list of advanced vision tasks that are intriguing to solve, but may exceed the capabilities of existing vision and vision-language models. To achieve such advanced visual intelligence, MM-REACT introduces a textual prompt design that can represent text descriptions, textualized spatial coordinates, and aligned file names for dense visual signals such as images and videos. MM-REACT's prompt design allows language models to accept, associate, and process multimodal information, thereby facilitating the synergetic combination of ChatGPT and various vision experts. Zero-shot experiments demonstrate MM-REACT's effectiveness in addressing the specified capabilities of interests and its wide application in different scenarios that require advanced visual understanding. Furthermore, we discuss and compare MM-REACT's system paradigm with an alternative approach that extends language models for multimodal scenarios through joint finetuning. Code, demo, video, and visualization are available at https://multimodal-react.github.io/

Scientific Large Language Models (Sci-LLMs) are transforming how knowledge is represented, integrated, and applied in scientific research, yet their progress is shaped by the complex nature of scientific data. This survey presents a comprehensive, data-centric synthesis that reframes the development of Sci-LLMs as a co-evolution between models and their underlying data substrate. We formulate a unified taxonomy of scientific data and a hierarchical model of scientific knowledge, emphasizing the multimodal, cross-scale, and domain-specific challenges that differentiate scientific corpora from general natural language processing datasets. We systematically review recent Sci-LLMs, from general-purpose foundations to specialized models across diverse scientific disciplines, alongside an extensive analysis of over 270 pre-/post-training datasets, showing why Sci-LLMs pose distinct demands -- heterogeneous, multi-scale, uncertainty-laden corpora that require representations preserving domain invariance and enabling cross-modal reasoning. On evaluation, we examine over 190 benchmark datasets and trace a shift from static exams toward process- and discovery-oriented assessments with advanced evaluation protocols. These data-centric analyses highlight persistent issues in scientific data development and discuss emerging solutions involving semi-automated annotation pipelines and expert validation. Finally, we outline a paradigm shift toward closed-loop systems where autonomous agents based on Sci-LLMs actively experiment, validate, and contribute to a living, evolving knowledge base. Collectively, this work provides a roadmap for building trustworthy, continually evolving artificial intelligence (AI) systems that function as a true partner in accelerating scientific discovery.

In an era defined by the explosive growth of data and rapid technological advancements, Multimodal Large Language Models (MLLMs) stand at the forefront of artificial intelligence (AI) systems. Designed to seamlessly integrate diverse data types-including text, images, videos, audio, and physiological sequences-MLLMs address the complexities of real-world applications far beyond the capabilities of single-modality systems. In this paper, we systematically sort out the applications of MLLM in multimodal tasks such as natural language, vision, and audio. We also provide a comparative analysis of the focus of different MLLMs in the tasks, and provide insights into the shortcomings of current MLLMs, and suggest potential directions for future research. Through these discussions, this paper hopes to provide valuable insights for the further development and application of MLLM.

We introduce MoMa, a novel modality-aware mixture-of-experts (MoE) architecture designed for pre-training mixed-modal, early-fusion language models. MoMa processes images and text in arbitrary sequences by dividing expert modules into modality-specific groups. These groups exclusively process designated tokens while employing learned routing within each group to maintain semantically informed adaptivity. Our empirical results reveal substantial pre-training efficiency gains through this modality-specific parameter allocation. Under a 1-trillion-token training budget, the MoMa 1.4B model, featuring 4 text experts and 4 image experts, achieves impressive FLOPs savings: 3.7x overall, with 2.6x for text and 5.2x for image processing compared to a compute-equivalent dense baseline, measured by pre-training loss. This outperforms the standard expert-choice MoE with 8 mixed-modal experts, which achieves 3x overall FLOPs savings (3x for text, 2.8x for image). Combining MoMa with mixture-of-depths (MoD) further improves pre-training FLOPs savings to 4.2x overall (text: 3.4x, image: 5.3x), although this combination hurts performance in causal inference due to increased sensitivity to router accuracy. These results demonstrate MoMa's potential to significantly advance the efficiency of mixed-modal, early-fusion language model pre-training, paving the way for more resource-efficient and capable multimodal AI systems.

In the quest for artificial general intelligence, Multi-modal Large Language Models (MLLMs) have emerged as a focal point in recent advancements. However, the predominant focus remains on developing their capabilities in static image understanding. The potential of MLLMs in processing sequential visual data is still insufficiently explored, highlighting the absence of a comprehensive, high-quality assessment of their performance. In this paper, we introduce Video-MME, the first-ever full-spectrum, Multi-Modal Evaluation benchmark of MLLMs in Video analysis. Our work distinguishes from existing benchmarks through four key features: 1) Diversity in video types, spanning 6 primary visual domains with 30 subfields to ensure broad scenario generalizability; 2) Duration in temporal dimension, encompassing both short-, medium-, and long-term videos, ranging from 11 seconds to 1 hour, for robust contextual dynamics; 3) Breadth in data modalities, integrating multi-modal inputs besides video frames, including subtitles and audios, to unveil the all-round capabilities of MLLMs; 4) Quality in annotations, utilizing rigorous manual labeling by expert annotators to facilitate precise and reliable model assessment. 900 videos with a total of 256 hours are manually selected and annotated by repeatedly viewing all the video content, resulting in 2,700 question-answer pairs. With Video-MME, we extensively evaluate various state-of-the-art MLLMs, including GPT-4 series and Gemini 1.5 Pro, as well as open-source image models like InternVL-Chat-V1.5 and video models like LLaVA-NeXT-Video. Our experiments reveal that Gemini 1.5 Pro is the best-performing commercial model, significantly outperforming the open-source models. Our dataset along with these findings underscores the need for further improvements in handling longer sequences and multi-modal data. Project Page: https://video-mme.github.io

Recent advancements in artificial intelligence (AI), particularly in large language models (LLMs) such as OpenAI-o1 and DeepSeek-R1, have demonstrated remarkable capabilities in complex domains such as logical reasoning and experimental coding. Motivated by these advancements, numerous studies have explored the application of AI in the innovation process, particularly in the context of scientific research. These AI technologies primarily aim to develop systems that can autonomously conduct research processes across a wide range of scientific disciplines. Despite these significant strides, a comprehensive survey on AI for Research (AI4Research) remains absent, which hampers our understanding and impedes further development in this field. To address this gap, we present a comprehensive survey and offer a unified perspective on AI4Research. Specifically, the main contributions of our work are as follows: (1) Systematic taxonomy: We first introduce a systematic taxonomy to classify five mainstream tasks in AI4Research. (2) New frontiers: Then, we identify key research gaps and highlight promising future directions, focusing on the rigor and scalability of automated experiments, as well as the societal impact. (3) Abundant applications and resources: Finally, we compile a wealth of resources, including relevant multidisciplinary applications, data corpora, and tools. We hope our work will provide the research community with quick access to these resources and stimulate innovative breakthroughs in AI4Research.

Human beings perceive the real world through a spectrum of sensory modalities, encompassing auditory, visual, and linguistic faculties. The journey towards achieving Artificial General Intelligence (AGI) necessitates the development of models that can emulate these multifaceted perceptual capabilities and comprehensively understand these diversified data. To this end, we introduce Nexus-O, an industry-level omni-perceptive and -interactive model capable of efficiently processing Audio, Image, Video, and Text data in any combination and output audio/text in an end-to-end way. We systematically investigate Nexus-O by addressing three key research questions: First, how can models be efficiently designed and trained to achieve tri-modal alignment, understanding and reasoning capabilities across multiple modalities? Second, what approaches can be implemented to evaluate tri-modal model robustness, ensuring reliable performance and applicability in real-world scenarios? Third, what strategies can be employed to curate and obtain high-quality, real-life scenario speech datasets? For the first question, we design and pre-train Nexus-O based on the vision-language model, rather than the language model. By pre-training the model over high-quality synthetic audio data, our model is capable of tri-modal perception and interaction. For the second question, we introduce a new audio testbed, Nexus-O-audio, comprising diverse Automatic Speech Recognition (ASR) samples, spanning various real-world scenarios, such as corporate meetings and live stream. For the third question, we design the speech data synthesis pipeline to obtain high-quality speech training datasets, covering various real-world scenarios. Comprehensive experimentation and an in-depth analysis of tri-modal alignment over latent space demonstrate the advantages of our model on downstream tasks.

AI scientists are emerging computational systems that serve as collaborative partners in discovery. These systems remain difficult to build because they are bespoke, tied to rigid workflows, and lack shared environments that unify tools, data, and analyses into a common ecosystem. In omics, unified ecosystems have transformed research by enabling interoperability, reuse, and community-driven development; AI scientists require comparable infrastructure. We present ToolUniverse, an ecosystem for building AI scientists from any language or reasoning model, whether open or closed. TOOLUNIVERSE standardizes how AI scientists identify and call tools, integrating more than 600 machine learning models, datasets, APIs, and scientific packages for data analysis, knowledge retrieval, and experimental design. It automatically refines tool interfaces for correct use by AI scientists, creates new tools from natural language descriptions, iteratively optimizes tool specifications, and composes tools into agentic workflows. In a case study of hypercholesterolemia, ToolUniverse was used to create an AI scientist to identify a potent analog of a drug with favorable predicted properties. The open-source ToolUniverse is available at https://aiscientist.tools.

Despite recent progress in multimodal agentic systems, existing approaches often treat image manipulation and web search as disjoint capabilities, rely heavily on costly reinforcement learning, and lack planning grounded in real tool-execution traces. To address these limitations, we present Skywork-R1V4, a 30B (A3B) parameter multimodal agentic model that unifies multimodal planning, active image manipulation ("thinking with images"), deep multimodal search, and, most critically, interleaved reasoning that dynamically alternates between visual operations and external knowledge retrieval. Trained solely via supervised fine-tuning on fewer than 30,000 high-quality, planning-execution-consistent trajectories and validated through stepwise consistency filtering, Skywork-R1V4 achieves state-of-the-art results across perception and multimodal search benchmarks: it scores 66.1 on MMSearch and 67.2 on FVQA, surpassing Gemini 2.5 Flash on all 11 metrics. Skywork-R1V4 exhibits emergent long-horizon reasoning at inference time, successfully orchestrating more than 10 tool calls to solve complex, multi-step tasks. Our results demonstrate that sophisticated agentic multimodal intelligence can be achieved through carefully curated supervised learning alone, without any reliance on reinforcement learning.

Large Multimodal Models (LMMs) exhibit impressive performance across various multimodal tasks. However, their effectiveness in cross-cultural contexts remains limited due to the predominantly Western-centric nature of most data and models. Conversely, multi-agent models have shown significant capability in solving complex tasks. Our study evaluates the collective performance of LMMs in a multi-agent interaction setting for the novel task of cultural image captioning. Our contributions are as follows: (1) We introduce MosAIC, a Multi-Agent framework to enhance cross-cultural Image Captioning using LMMs with distinct cultural personas; (2) We provide a dataset of culturally enriched image captions in English for images from China, India, and Romania across three datasets: GeoDE, GD-VCR, CVQA; (3) We propose a culture-adaptable metric for evaluating cultural information within image captions; and (4) We show that the multi-agent interaction outperforms single-agent models across different metrics, and offer valuable insights for future research. Our dataset and models can be accessed at https://github.com/MichiganNLP/MosAIC.

Recent advancements in large foundation models have remarkably enhanced our understanding of sensory information in open-world environments. In leveraging the power of foundation models, it is crucial for AI research to pivot away from excessive reductionism and toward an emphasis on systems that function as cohesive wholes. Specifically, we emphasize developing Agent AI -- an embodied system that integrates large foundation models into agent actions. The emerging field of Agent AI spans a wide range of existing embodied and agent-based multimodal interactions, including robotics, gaming, and healthcare systems, etc. In this paper, we propose a novel large action model to achieve embodied intelligent behavior, the Agent Foundation Model. On top of this idea, we discuss how agent AI exhibits remarkable capabilities across a variety of domains and tasks, challenging our understanding of learning and cognition. Furthermore, we discuss the potential of Agent AI from an interdisciplinary perspective, underscoring AI cognition and consciousness within scientific discourse. We believe that those discussions serve as a basis for future research directions and encourage broader societal engagement.

Although Large Language Models (LLMs) and Large Multimodal Models (LMMs) exhibit impressive skills in various domains, their ability for mathematical reasoning within visual contexts has not been formally examined. Equipping LLMs and LMMs with this capability is vital for general-purpose AI assistants and showcases promising potential in education, data analysis, and scientific discovery. To bridge this gap, we present MathVista, a benchmark designed to amalgamate challenges from diverse mathematical and visual tasks. We first taxonomize the key task types, reasoning skills, and visual contexts from the literature to guide our selection from 28 existing math-focused and visual question answering datasets. Then, we construct three new datasets, IQTest, FunctionQA, and PaperQA, to accommodate for missing types of visual contexts. The problems featured often require deep visual understanding beyond OCR or image captioning, and compositional reasoning with rich domain-specific tools, thus posing a notable challenge to existing models. We conduct a comprehensive evaluation of 11 prominent open-source and proprietary foundation models (LLMs, LLMs augmented with tools, and LMMs), and early experiments with GPT-4V. The best-performing model, Multimodal Bard, achieves only 58% of human performance (34.8% vs 60.3%), indicating ample room for further improvement. Given this significant gap, MathVista fuels future research in the development of general-purpose AI agents capable of tackling mathematically intensive and visually rich real-world tasks. Preliminary tests show that MathVista also presents challenges to GPT-4V, underscoring the benchmark's importance. The project is available at https://mathvista.github.io/.