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Hormone Therapy and Ipilimumab in Treating Patients With Advanced Prostate Cancer Study Overview ================= Brief Summary ----------------- RATIONALE: Androgens can cause the growth of prostate cancer cells. Antihormone therapy, such as leuprolide acetate, goserelin, flutamide, or bicalutamide may lessen the am...
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Cancer, Physical Activity and Quality of Life- a Longterm Follow up Study Overview ================= Brief Summary ----------------- This project is a 6-8-years follow-up of a randomized controlled trial testing a stepped care stress management program. The main goal is to examining differences in long-term effects on...
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Weight-Adjusted Dosing of 3-OHB in Patients With Chronic Heart Failure Study Overview ================= Brief Summary ----------------- We aim to investigate the hemodynamic effects of weight-adjusted dosing of ketone monoester en patients with chronic heart failure. Official Title ----------------- Weight-Adjusted D...
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Safety and Efficacy of Using HDH Device and Method - a Novel Sutureless Vascular Anastomosis Study Overview ================= Brief Summary ----------------- The HDH device is intended for creating sutureless vascular anastomosis in various blood vessels. The HDH device consists of four parts: an elastic tube (graft),...
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Reducing Adverse Drug Events in the Nursing Home Study Overview ================= Brief Summary ----------------- Medications are the single most common form of treatment in the long-term care setting, and often represent the most efficacious (and cost-effective) therapeutic modality used in this clinical setting. How...
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Tea and Forearm Blood Flow Study Overview ================= Brief Summary ----------------- The study will explore the benefit of tea for microcirculation. Subjects will consume tea ar a placebo matched for taste and appearance in a blinded cross over design. Detailed Description ----------------- Epidemiological stu...
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Clinical Features of Smoker Patients With Chronic Obstructive Pulmonary Disease Study Overview ================= Brief Summary ----------------- Smoking is the most important factor in the etiology of COPD. Some of the patients with COPD continue to smoke despite knowing this situation or they cannot quit even if they...
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A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD Study Overview ================= Brief Summary ----------------- The purpose of this study is to evaluate the efficacy and safety of ensifentrine in patients with moderate to severe Chronic Obstructive Pulmonary Disease ...
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A Clinical Trial of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Relapsed or Refractory Breast, Colorectal and Non-Small Cell Lung Cancer (0683-011)(TERMINATED) Study Overview ================= Brief Summary ----------------- This is an investigational study to determine the response rate of relapsed/r...
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Acute Exposure of Simulated Hypoxia on Pulmonary Artery Pressure and Right Heart Function (Echo) Study Overview ================= Brief Summary ----------------- Randomized crossover trial in patients with Pulmonary Hypertension (PAH, CTEPH) to assess the acute response to simulated altitude (FiO2:15.1, equivalent to ...
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EDWARDS INTUITY Valve System CADENCE Study Study Overview ================= Brief Summary ----------------- The study purpose is to compare the EDWARDS INTUITY valve system with commercially available stented aortic bioprostheses, in patients requiring aortic valve replacement surgery with coronary artery bypass. Det...
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Study to Investigate an Immunomodulatory Therapy in Adult Patients With Perennial Allergic Rhinoconjunctivitis Study Overview ================= Brief Summary ----------------- The purpose of the study is to test the efficacy of a vaccine against house dust mite and/or cat allergy compared to placebo in adult patients....
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A Phase IV Study to Assess the Safety of EupentaTM Inj Study Overview ================= Brief Summary ----------------- A prospective, open-label, interventional phase IV study to assess the safety of EupentaTM Inj.{fully liquid pentavalent vaccine, Adsorbed Diphtheria-Tetanus-whole-cell Pertussis-Hepatitis B (rDNA [r...
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Eastern Caribbean Health Outcomes Research Network (ECHORN) Study Overview ================= Brief Summary ----------------- The Eastern Caribbean Health Outcomes Research Network (ECHORN) is a collaborative research study that examines the lifestyles, eating habits, and health behaviors associated with cancer, diabet...
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Investigating the Gut Microbiota Modulation Effects of Allicin for Cardiovascular Disease Protection and Establishing Microbiota Directed Personalized Nutrition Guidance With Novel Humanized Gnotobiotic Mice Model, Microbial Culturomics and Metabolomic Technique Study Overview ================= Brief Summary ---------...
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Platelet-Rich Plasma in the Treatment of Patients With Idiopathic Carpal Tunnel Syndrome Study Overview ================= Brief Summary ----------------- This is a randomized controlled trial in a cohort of Egyptian patients suffered from mild to moderate idiopathic carpal tunnel. They were randomly divided into two g...
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Efficacy and Safety of Sofosbuvir/Velpatasvir ± Ribavirin for 12 Weeks in Adults With Chronic HCV Infection and Decompensated Cirrhosis Study Overview ================= Brief Summary ----------------- The primary objectives of this study are to evaluate the antiviral efficacy, safety, and tolerability of sofosbuvir/ve...
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Strategies to Continue Gynae-oncology Services in the Era of COVID-19 Outbreak: Concerns and Challenges in a Referral Centre in Malaysia Study Overview ================= Brief Summary ----------------- A short survey involving 100 participants was conducted online to explore the understanding of Covid 19 pandemic impa...
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Study of ME-401 in Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma Study Overview ================= Brief Summary ----------------- The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of ME-401 in the treatment of Japanese participants with Relapsed or Re...
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Evaluation of the Interaction Between Low Dose Sulfamethoxazole-Trimethoprim and Zidovudine Study Overview ================= Brief Summary ----------------- To determine if the pharmacokinetics of low doses of zidovudine (AZT) (that is, how fast AZT reaches the blood, what concentration of AZT is attained in the blood...
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Muscle Relaxation for Short Procedures Study Overview ================= Brief Summary ----------------- Succinylcholine is commonly used for neuromuscular relaxation for short procedures such as rigid bronchoscopy. A more modern alternative is the application of low-dose rocuronium, reversed by low-dose sugammadex. Th...
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Balneotherapy and Anxiety During SARS-CoV-2 Pandemic Study Overview ================= Brief Summary ----------------- Investigators will measure the level of anxiety and fear of Covid during the balneological treatment in patients. They are interested in the effect of general trust and resilience on the level of anxie...
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Accessory Pathway Antegrade Effective Refractory Period Among WPW Patients: the Risk in Relation to the Location Study Overview ================= Brief Summary ----------------- To correlate the antegrade effective refractory period of the accessory pathway with its anatomical location in the heart. To investigate whe...
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Assessing the Analgesic Efficacy of Naproxen Sodium in Postsurgical Dental Pain. Study Overview ================= Brief Summary ----------------- To evaluate the analgesic efficacy of a single, oral dose of a naproxen sodium extended-release tablet, compared to placebo in postsurgical dental pain. Official Title ----...
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The Effect of Telerehabilitation on Symptoms in Fibromyalgia Patients Study Overview ================= Brief Summary ----------------- The aim of this study is to evaluate the effect of telerehabilitation-based high-intensity interval upper extremity exercise training on biochemistry parameters and disease symptoms in...
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The Risk of Exacerbation of Chronic Hepatitis B After Percutaneous Radiofrequency Ablation of Hepatocellular Carcinoma Study Overview ================= Brief Summary ----------------- This study aim to find out the risk of exacerbation of chronic hepatitis B after percutaneous radiofrequency ablation (RFA) or hepatect...
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A Study in Healthy Men to Test How BI 456906 is Processed in the Body Study Overview ================= Brief Summary ----------------- This trial is intended to examine the basic pharmacokinetics of BI 456906 and total [14C]-radioactivity, including mass balance, excretion pathways and metabolism following a single su...
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Determining Optimal Dose and Duration of Diuretic Treatment in People With Acute Heart Failure (The DOSE-AHF Study) Study Overview ================= Brief Summary ----------------- Heart failure is a disorder in which the heart does not pump blood adequately. This can lead to several serious problems, including reduce...
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Surgical Therapy and Survival in HCC/ C.F. Zhang et al. Study Overview ================= Brief Summary ----------------- This study utilizes a new method to explore compare the overall survival (OS) and cancer-specific survival (CSS) in patients aged 18-45 years with stage I-II HCC who underwent different types of sur...
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Montelukast in Perennial Allergic Rhinitis - 2001-2002 Study (0476-246) Study Overview ================= Brief Summary ----------------- This study will assess the ability of montelukast to improve the signs and symptoms of perennial allergic rhinitis compared to placebo. Cetirizine is included in the study as an acti...
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Behavioral Pharmacology Associated With Cigar Smoking Study Overview ================= Brief Summary ----------------- Lovelace Scientific Resources is conducting clinical research study for cigar smokers. This study will be evaluating the behaviors of cigar smokers and the short term effects of cigar smoking. A cigar...
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[Trial of device that is not approved or cleared by the U.S. FDA] Study Overview ================= Official Title ----------------- [Trial of device that is not approved or cleared by the U.S. FDA] Participation Criteria ================= Ages Eligible for Study ----------------- Minimum Age: Maximum Age: Study...
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A Trial of Everolimus-eluting Stents and Paclitaxel-eluting Stents for Coronary Revascularization in Daily Practice: The COMPARE Trial Study Overview ================= Brief Summary ----------------- Instead of treating in-stent restenosis, the best strategy for patients is preventing in-stent restenosis. Recent advan...
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The Effect of Nefecon® in Patients With Primary IgA Nephropathy at Risk of Developing End-stage Renal Disease Study Overview ================= Brief Summary ----------------- The objective of the study is to evaluate efficacy and safety of two different doses of NEFECON in the treatment of patients with primary IgA ne...
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Lornoxicam vs. Paracetamol After Lower Abdominal Surgery Study Overview ================= Brief Summary ----------------- Background: The aim of this prospective, randomized, double-blind study is to determine the most effective supplemental analgesic, paracetamol or lornoxicam for postoperative pain relief after lowe...
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Bezafibrate Plus Berberine in Mixed Dyslipidemia Study Overview ================= Brief Summary ----------------- Dyslipidemia, is a cardiovascular risk factor of great importance whose prevalence has increased over the last decade. Part of the components of metabolic syndrome and consensus so far contemplated to incr...
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Open Label Non-comparative Clinical Trial of Tigecycline in Patients With Catheter Infection Study Overview ================= Brief Summary ----------------- Tigecycline is being developed as an agent that overcomes tetracycline-resistance mechanisms and provides activity against emerging multi-drug resistant pathogen...
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ALX-0171 Safety Study in Adults With Hyperresponsive Airways Study Overview ================= Brief Summary ----------------- This is a Phase I, single-centre, open label study to evaluate the occurrence and subsequent reversibility and prevention, of bronchoconstriction following single and repeated oral inhalations ...
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Concurrent Chemoradiotherapy Combination With Anlotinib for Unresectable Stage III NSCLC Patients Study Overview ================= Brief Summary ----------------- The purpose of this study is to determine whether concurrent chemoradiotherapy combination with Anlotinib is safe, effective in the treatment of unresectabl...
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Effectiveness of a Team-based Follow-up Program in General Practice Among People With Chronic Conditions Study Overview ================= Brief Summary ----------------- The study will develop and evaluate the effectiveness of a team-based follow-up program in general practice (GP) among people with chronic conditions...
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Application of Standardized Green Channel Treatment System for Ischemic Stroke in Xi 'an Study Overview ================= Brief Summary ----------------- Objective: To observe the practical application of the standardized green channel treatment system for stroke in Xi 'an in the real world. Methods: Clinical data and...
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Ranibizumab Versus Aflibercept for CRVO in Young Patients. Study Overview ================= Brief Summary ----------------- this study will compare the efficacy and safety of use either Ranibizumab and Aflibercept in treatment of macular edema resulting from non ischemic central retinal vein occlusion in patients youn...
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Study of the Efficacy and Safety of NPC-15 for Sleep Disorders of Children With Neurodevelopmental Disorders Study Overview ================= Brief Summary ----------------- The purpose of this study is to evaluate the efficacy on sleep latency with electronic sleep diaries and the safety of NPC-15. Detailed Descript...
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SuperNO2VA™ and General Anesthesia Postoperative Care Study Overview ================= Brief Summary ----------------- The purpose of the study is to randomly and prospectively evaluate the differences in outcomes between the control group (closed full facemask immediate post-extubation with standard oxygenating devic...
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Effects of Strength Training on Freestyle Swimming Performance and Core Muscles Strength in Swimmers Study Overview ================= Brief Summary ----------------- To compare the effectiveness performance and core muscles of Strength Training . strength in swimmers on freestyle swimming Detailed Description -------...
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Intense Monitoring Study on Tyvyt Study Overview ================= Brief Summary ----------------- The study is a multi-center, prospective, non-interventional and observational study, and will collect data on the safety and efficacy of Tyvyt® in the treatment of Chinese patients with relapsed or refractory classical ...
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Resolution of Comorbidities, Safety and Efficacy of Greater Curvature Plication in Obese Patients. Study Overview ================= Brief Summary ----------------- Various gastric restrictive procedures have evolved over the years but abandoned due to poor long term weight loss, food intolerance or severe gastroesopha...
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Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma Study Overview ================= Brief Summary ----------------- This pilot phase II trial studies how well selumetinib works in treating patients with neurofibromatosis type 1 and cutaneous neurofibromas. Selumetinib may stop th...
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L-arginine and Asymmetric Dimethylarginine (ADMA) and Lifestyle Protocols Study Overview ================= Brief Summary ----------------- Low serum L-arginine (Arg) and high asymmetric dimethylarginine (ADMA) can predict microvascular complications in type 2 diabetes (T2DM). The investigators examined whether or not ...
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National Acute Promyelocytic Leukemia (APL) Observational Study NAPOLEON-Registry of the German AML Intergroup Study Overview ================= Brief Summary ----------------- The registry aims to document epidemiologic data, treatment and long-term outcome as well as quality of life of patients with APL. Additionally...
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Microcurrent Stimulation Therapy for Nonexudative Age-related Macular Degeneration (i-SIGHT) Study Overview ================= Brief Summary ----------------- Evaluate the safety and efficacy of transpalpebral microcurrent stimulation (MCS) therapy for patients with nonexudative (dry) age-related macular degeneration (...
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Prevention of Invasive Fungal Infections (IFIs) in Subjects Receiving Chemotherapy for Acute Lymphoblastic Leukemia Study Overview ================= Brief Summary ----------------- The study aims to investigate whether prophylaxis with liposomal amphotericin B (AmBisome®) can reduce the incidence of invasive fungal in...
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Cost-Effectiveness of Routine Follow-up Visits in Patients With a Pacemaker: The Followpace Study Study Overview ================= Brief Summary ----------------- The overall objective of the study is to quantify the true prognostic value and cost-effectiveness of routine follow-up visits in patients who receive an ap...
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Neurological Outcome in Surgical and Non-surgical Septic Patients Study Overview ================= Brief Summary ----------------- Systemic inflammation and sepsis cause multi organ failure including severe neurologic impairment in the course of disease. Neurologic failure typically presents as critical-illness-polyne...
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Excimer Light Treatment for Idiopathic Guttate Hypomelanosis: A Pilot Study Study Overview ================= Brief Summary ----------------- This pilot study will consist of 10 adult subjects with symmetric idiopathic guttate hypomelanosis on the lower legs. Subjects will be randomized to which extremity (right or lef...
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Oral Health Related Quality of Life of Patients With Rare Diseases: a Qualitative Approach Study Overview ================= Brief Summary ----------------- The main objective of the study is to assess the oral health-related quality of life of patients with rare diseases and followed in the rare disease centers of exp...
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Physiologic Ocular Changes During Pregnancy in Women With High Myopia. Study Overview ================= Brief Summary ----------------- The prevalence of myopia is seemingly increasing, and it is one of the major causes of blindness. High myopia is defined as a refractive error with spherical equivalent exceeding -6 d...
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Efficacy of Sodium Thiosulfate in Shoulder Pain in Calcific Tendinitis of the Rotator Cuff Study Overview ================= Brief Summary ----------------- Calcific tendinitis of the rotator cuff is one of the most common causes of shoulder pain. Ultrasound guided percutaneous lavage (UGPL or barbotage or irrigation) o...
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Gait Analysis Following Total Ankle Replacement and Subtalar Fusion Study Overview ================= Brief Summary ----------------- Subtalar fusion is commonly performed in post-traumatic subtalar osteoarthritis, rheumatoid arthritis, posterior tibial tendon dysfunction, tarsal coalition and primary subtalar osteoart...
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Prevention of Recurrent Hepatitis B After Liver Transplantation Study Overview ================= Brief Summary ----------------- Hepatitis B accounts for approximately 5000 deaths per year in the United States. Liver transplantation offers the only hope for patients who develop end-stage liver disease. Early results o...
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Pilot and Feasibility Study of a MAWDS (Medications, Activity, Weight, Diet and Symptoms) Heart Failure Mobile Platform Study Overview ================= Brief Summary ----------------- The purpose of this study is to create a smartphone app that delivers the educational content of the current Intermountain MAWDS* prog...
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T-ABA Group Based Early Intervention For Parents of Children With ASD Study Overview ================= Brief Summary ----------------- This study is a 10-week, randomized, parallel groups design which will evaluate the efficacy of T-ABA with combined parent training and individual child sessions versus T-ABA with indi...
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An Integrated Community-based Intervention Package in Improving Maternal and Neonatal Health Outcomes Study Overview ================= Brief Summary ----------------- This study aims to improve maternal, neonatal and infant health outcomes through an integrated community-based intervention package in Jimma Zone, South...
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Diagnosis of EIB in Young Elite Athletes (13-18 y) Study Overview ================= Brief Summary ----------------- The investigators recently observed airway inflammation and increased damage-associated molecular pattern (DAMP) level in sputum of children (age 11-12y) and adolescents (18-23y) from elite sport program...
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Molecular Genetics of Suicidal Behavior Study Overview ================= Brief Summary ----------------- Suicide is a major health problem that causes annually a million death worldwide. In the stress-vulnerability model, suicidal behavior (SB) results from the interaction between an individual's predisposition and st...
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Assessing the Role of the NLRP3 Inflammasome in Intercritical Gout Study Overview ================= Brief Summary ----------------- Gout is an autoinflammatory disease characterized by flares of painful joint inflammation. This inflammation occurs in response to uric acid that crystallizes. After a gout attack, patien...
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Pharmacist Intervention to Decrease Medication Errors in Heart Disease Patients (The PILL-CVD Study) Study Overview ================= Brief Summary ----------------- Many people who have recently left the hospital have difficulties managing their medications, and medication errors are common. Patients with low health ...
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Effect of TAP Block on Ventilatory Function Following Abdominal Surgery Study Overview ================= Brief Summary ----------------- Abdominal surgery impairs ventilation. Postoperative pain accounts for this impairment. Regional analgesia is known to reduce pain, thus to limit ventilatory impairment. The investig...
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GOS Prebiotic Effect in Children Constipation Study Overview ================= Brief Summary ----------------- Some prebiotics are useful for improving symptoms related to constipation, but clinical trials including infants and older children are scarce. A double-blind, placebo-controlled, crossover clinical trial was...
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A Study to Test Efficacy and Safety of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis Study Overview ================= Brief Summary ----------------- The purpose of the MycarinGstudy is to demonstrate the clinical efficacy and to assess safety and tolerability of rozanolixizumab in patients with...
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Modulation of Intestinal and Pulmonary Inflammation by Lactobacillus Diet Supplementation in Pediatric Cystic Fibrosis Study Overview ================= Brief Summary ----------------- Pulmonary inflammation is an independent risk factor for disease progression in cystic fibrosis patients (CF). Yet, no effective treatm...
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The Effect of Sodium Zirconium Cyclosilicate on Albuminuria in Patients With Type 2 Diabetes and Hyperkalemia Study Overview ================= Brief Summary ----------------- To investigate whether concomitant treatment with Lokelma can improve the efficacy of standard blockade of the renin-angiotensin system in patie...
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Networked-Based Recovery With User Involvement Study Overview ================= Brief Summary ----------------- Introduction Over the past 20 years there has been an overall deterioration in the mental health of young people. An increasing number of young people are diagnosed with emotional disorders such as anxiety a...
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Testing the Addition of M3814 (Peposertib) to Radiation Therapy for Patients With Advanced Head and Neck Cancer Who Cannot Take Cisplatin Study Overview ================= Brief Summary ----------------- This phase I trial investigates the side effects and best dose of peposertib when given together with radiation ther...
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Role of Hyoid Suspension With Barbed Reposition Pharyngoplasty in Management of Lateral Pharyngeal Wall Collapse in Obstructive Sleep Apnea Patients Study Overview ================= Brief Summary ----------------- Aim of the study To determine the exact role of hyoid bone suspension surgery in splinting lateral pharyn...
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Efficacy of a Brief Intervention to Improve Sexual and Gender Minorities' Mental Health: Randomized Controlled Trial. Study Overview ================= Brief Summary ----------------- Experiences of violence, from micro to physical aggressions, have a deleterious impact on mental health. According to the Minority Stres...
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Evaluation of Two Boost Radiation Schedules in Post Lumpectomy Early Stage Carcinoma Breast Study Overview ================= Brief Summary ----------------- In a general radiation oncology practice, breast cancer typically comprises approximately 25% of the total patient caseload.1 Surgery is the primary modality of t...
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Efficacy and Safety of YKP3089 in Subjects With Treatment Resistant Partial Onset Seizures Study Overview ================= Brief Summary ----------------- This study is to evaluate the efficacy of YKP3089 in reducing seizure frequency when compared to baseline in subjects with partial onset seizures not fully control...
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Safety, Tolerability, and Pharmacokinetics of RSV Monoclonal Antibody RSM01 in Healthy Adults Study Overview ================= Brief Summary ----------------- Gates MRI-RSM01-101 is a Phase 1, randomized, double-blind, placebo-controlled, dose-escalation study to evaluate the safety and tolerability, pharmacokinetics,...
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Thalidomide in Treating Patients With Thyroid Cancer Study Overview ================= Brief Summary ----------------- RATIONALE: Thalidomide may stop the growth of thyroid cancer by stopping blood flow to the tumor. PURPOSE: Phase II trial to study the effectiveness thalidomide in treating patients who have thyroid ca...
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Retrospective Evaluation of Risk Factors for Lower Outcomes After Vitrectomy With ILM Flap Technique Study Overview ================= Brief Summary ----------------- A retrospective review of medical charts of patients having undergone vitrectomy with ILM Peeling and ILM flap technique for macular hole repair. Detail...
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A Study to Determine Safety of Durvalumab After Sequential Chemo Radiation in Patients With Unresectable Stage III Non-Small Cell Lung Cancer Study Overview ================= Brief Summary ----------------- This is a Phase II, open-label, multi-centre study to determine the safety of a fixed dose of Durvalumab (MEDI47...
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Kyrgyz Asthma Rehabilitation at High Altitude Study Overview ================= Brief Summary ----------------- prospective controlled interventional trial evaluating the efficacy of a 3-weeks asthma rehabilitation program at high altitude (3200m) and low altitude (760m) on lung function and asthma control. Detailed D...
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The Effect of Melatonin Administration on Sedation Level as Adjuvant to Propofol Study Overview ================= Brief Summary ----------------- This study assess the effect of administration of exogenous melatonin as adjuvant to propofol on the level of sedation and consequently the rate of propofol infusion. Detai...
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Epidemiology of Human Papillomavirus Infection Among Women Living on the Maroni and the Oyapock Rivers Study Overview ================= Brief Summary ----------------- Cervical cancer is the second most frequent cancer of women in French Guiana. Studies have shown that populations living in remote villages in the inte...
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Microbiome and Immune Profiling in Infant With Cow's Milk Allergy Study Overview ================= Brief Summary ----------------- Non-IgE-mediated cow's milk allergy (CMPA) is associated to gastrointestinal symptoms, and its cause remains poorly understood, limiting the identification of specific markers to help with...
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Developing and Testing a Low Cost Opportunistic Glaucoma Screening Model by Non-physician Graders in Vietnam Study Overview ================= Brief Summary ----------------- This study aims to develop a training course for screening glaucoma using fundus images obtained during diabetic retinopathy screening by non-phy...
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Preventive Effect of Enoxaparin, Pentoxifylline and Ursodeoxycholic Acid to Radiation Induced Liver Toxicity Study Overview ================= Brief Summary ----------------- To evaluate whether a combination regimen of pentoxifylline, ursodeoxycholic acid and enoxaparin provides a protective effect on the liver parenc...
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A Trial of AK117 (Anti-CD47 Antibody) in Patients With Acute Myeloid Leukemia Study Overview ================= Brief Summary ----------------- This is a open label, phase Ib/II study. All patients are diagnosed with AML, Eastern Cooperative Oncology Group (ECOG) performance status 0-3. The purpose of this study is to ...
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Effect of Recombinant Human EPO on the Postoperative Neurologic Outcome in Pediatric Moyamoya Patients Study Overview ================= Brief Summary ----------------- This study evaluates the effect of recombinant human erythropoietin (rHuEPO) on the neovascularization of pediatric moyamoya disease patients. rHuEPO w...
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Functional Imaging of Tumor and Normal Tissue Study Overview ================= Brief Summary ----------------- Dynamic contrast-enhanced (DCE) - magnetic resonance imaging (MRI), diffusion-weighted (DW)-MRI, and fludeoxyglucose - positron emission tomography - computed tomography (FDG-PET-CT) are three modalities that...
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CORonary Diet Intervention With Olive Oil and Cardiovascular PREVention Study Overview ================= Brief Summary ----------------- The purpose of this study is to compare the effects of the consumption of two different dietary patterns (low fat versus Mediterranean Diet) on the incidence of cardiovascular events...
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Inositol Treatment in Different Type of PCOS Phenotype Study Overview ================= Brief Summary ----------------- Evaluation of the efficacy of inositol treatment in women with PCOS in relation to the phenotype (according to the Rotterdam Criteria) Official Title ----------------- The Effect of Inositol Treatme...
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Effect of Coffee and Tea Consumption on Adolescent Weight Control Study Overview ================= Brief Summary ----------------- Introduction: The influence of tea or coffee supplementation on body weight in adolescents has never been tested. The aim of the present study was to investigate the effect of tea and coff...
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Validation of Neurokeeper's Algorithm on Patients Undergoing Carotid Endarterectomy Study Overview ================= Brief Summary ----------------- The primary objective of the study is to validate an EEG base algorithm system to detect and monitor changes in cerebral electrophysiological parameters as compared to cl...
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Impact of a Minimally Invasive Approach to Laparoscopic Hysterectomy on Postoperative Recovery Study Overview ================= Brief Summary ----------------- Background Managing perioperative stress, including endocrino-metabolic changes and, inflammatory and pain responses, is a major challenge to improve patient's...
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Day Case Colectomy: Optimizing Short Stay-surgery. Study Overview ================= Brief Summary ----------------- HRV measurement of patients recovering from laparoscopic colorectal resection for any pathology. Detailed Description ----------------- Patients scheduled for colorectal surgery are recruited to the stu...
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Platelet Rich Plasma for the Management of Post-Viral Olfactory Dysfunction. Study Overview ================= Brief Summary ----------------- SARS COV-19 has resulted in prolonged olfactory dysfunction in many patients. The investigators aim to compare the effect of topical platelet-rich plasma (test) vs saline (place...
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Conventional Antibiotic Prophylaxis Versus Add-On 5 Days Levofloxacin Before Percutaneous Nephrolithotomy Study Overview ================= Brief Summary ----------------- To evaluate whether 5 days of levofloxacin before percutaneous nephrolithotomy (PCNL) in reducing upper urinary tract infection and urosepsis after ...
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Prospective Evaluation of Stent Patency in Patients With Benign Biliary Obstruction of the Wing Biliary Stent (Viaduct™) Study Overview ================= Brief Summary ----------------- Endoscopic retrograde cholangiopancreatography (ERCP) with plastic stent placement for resolution of biliary obstruction has been the...
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